Christofer Lendel

Summary

Affiliation: Royal Institute of Technology
Country: Sweden

Publications

  1. pmc Biophysical characterization of Z(SPA-1)--a phage-display selected binder to protein A
    Christofer Lendel
    KTH Biotechnology, Royal Institute of Technology KTH, SE 106 91 Stockholm, Sweden
    Protein Sci 13:2078-88. 2004
  2. doi request reprint Detergent-like interaction of Congo red with the amyloid beta peptide
    Christofer Lendel
    Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK
    Biochemistry 49:1358-60. 2010
  3. doi request reprint Hydrophobicity and conformational change as mechanistic determinants for nonspecific modulators of amyloid β self-assembly
    Axel Abelein
    Department of Biochemistry and Biophysics, Stockholm University, Svante Arrhenius v 16, SE 106 91 Stockholm, Sweden
    Biochemistry 51:126-37. 2012
  4. ncbi request reprint Thermodynamics of folding and binding in an affibody:affibody complex
    Jakob Dogan
    School of Biotechnology, Royal Institute of Technology KTH, Stockholm, Sweden
    J Mol Biol 359:1305-15. 2006
  5. ncbi request reprint Structural basis for molecular recognition in an affibody:affibody complex
    Christofer Lendel
    School of Biotechnology, Royal Institute of Technology KTH, Stockholm, Sweden
    J Mol Biol 359:1293-304. 2006
  6. doi request reprint On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of alpha-synuclein with Congo red and lacmoid
    Christofer Lendel
    Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK
    Biochemistry 48:8322-34. 2009
  7. doi request reprint 3D J-resolved NMR spectroscopy for unstructured polypeptides: fast measurement of 3J HNH alpha coupling constants with outstanding spectral resolution
    Christofer Lendel
    Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK
    J Biomol NMR 44:35-42. 2009
  8. doi request reprint Transient small molecule interactions kinetically modulate amyloid β peptide self-assembly
    Axel Abelein
    Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden
    FEBS Lett 586:3991-5. 2012

Collaborators

Detail Information

Publications8

  1. pmc Biophysical characterization of Z(SPA-1)--a phage-display selected binder to protein A
    Christofer Lendel
    KTH Biotechnology, Royal Institute of Technology KTH, SE 106 91 Stockholm, Sweden
    Protein Sci 13:2078-88. 2004
    ..This stabilization is better correlated to changes in helix propensity than to an expected increase in polar versus nonpolar surface area of the fully folded state...
  2. doi request reprint Detergent-like interaction of Congo red with the amyloid beta peptide
    Christofer Lendel
    Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK
    Biochemistry 49:1358-60. 2010
    ..Although CR promotes beta sheet formation and peptide aggregation, it may also solubilize toxic protein species, making them less harmful to critical cellular components and thereby reducing amyloid toxicity...
  3. doi request reprint Hydrophobicity and conformational change as mechanistic determinants for nonspecific modulators of amyloid β self-assembly
    Axel Abelein
    Department of Biochemistry and Biophysics, Stockholm University, Svante Arrhenius v 16, SE 106 91 Stockholm, Sweden
    Biochemistry 51:126-37. 2012
    ....
  4. ncbi request reprint Thermodynamics of folding and binding in an affibody:affibody complex
    Jakob Dogan
    School of Biotechnology, Royal Institute of Technology KTH, Stockholm, Sweden
    J Mol Biol 359:1305-15. 2006
    ..The combined structure and thermodynamics data suggest that protein properties are not likely to be a serious limitation for the development of engineered binding proteins based on the Z domain...
  5. ncbi request reprint Structural basis for molecular recognition in an affibody:affibody complex
    Christofer Lendel
    School of Biotechnology, Royal Institute of Technology KTH, Stockholm, Sweden
    J Mol Biol 359:1293-304. 2006
    ..A thermodynamic characterization of Z(Taq) and anti-Z(Taq) is presented in an accompanying paper...
  6. doi request reprint On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of alpha-synuclein with Congo red and lacmoid
    Christofer Lendel
    Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK
    Biochemistry 48:8322-34. 2009
    ....
  7. doi request reprint 3D J-resolved NMR spectroscopy for unstructured polypeptides: fast measurement of 3J HNH alpha coupling constants with outstanding spectral resolution
    Christofer Lendel
    Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK
    J Biomol NMR 44:35-42. 2009
    ..The experiment is demonstrated for the intrinsically unstructured 14 kDa protein alpha-synuclein...
  8. doi request reprint Transient small molecule interactions kinetically modulate amyloid β peptide self-assembly
    Axel Abelein
    Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden
    FEBS Lett 586:3991-5. 2012
    ..These findings suggest that even such weak binders might be effective as therapeutics against pathogenic protein aggregation...