Erik Fransen

Summary

Affiliation: Royal Institute of Technology
Country: Sweden

Publications

  1. ncbi Ionic mechanisms in the generation of subthreshold oscillations and action potential clustering in entorhinal layer II stellate neurons
    Erik Fransen
    Department of Numerical Analysis and Computer Science, Royal Institute of Technology, Stockholm, Sweden
    Hippocampus 14:368-84. 2004
  2. ncbi Functional role of entorhinal cortex in working memory processing
    Erik Fransen
    Department of Numerical Analysis and Computer Science, Royal Institute of Technology, SE 10044 Stockholm, Sweden
    Neural Netw 18:1141-9. 2005
  3. ncbi Mechanism of graded persistent cellular activity of entorhinal cortex layer v neurons
    Erik Fransen
    School of Computer Science and Communication, Royal Institute of Technology, SE 100 44 Stockholm, Sweden
    Neuron 49:735-46. 2006
  4. ncbi Simulations of the role of the muscarinic-activated calcium-sensitive nonspecific cation current INCM in entorhinal neuronal activity during delayed matching tasks
    Erik Fransen
    Department of Numerical Analysis and Computer Science, Royal Institute of Technology, S-100 44 Stockholm, Sweden
    J Neurosci 22:1081-97. 2002
  5. ncbi Reversing nerve cell pathology by optimizing modulatory action on target ion channels
    Jenny Tigerholm
    Department of Computational Biology, School of Computer Science and Communication, Royal Institute of Technology, Stockholm, Sweden
    Biophys J 101:1871-9. 2011
  6. ncbi Role of A-type potassium currents in excitability, network synchronicity, and epilepsy
    Erik Fransen
    Department of Computational Biology, School of Computer Science and Communication, Royal Institute of Technology, AlbaNova University Center, Stockholm, Sweden
    Hippocampus 20:877-87. 2010
  7. ncbi Integration of synchronous synaptic input in CA1 pyramidal neuron depends on spatial and temporal distributions of the input
    Jenny Tigerholm
    Department of Computational Biology, School of Computer Science and Communication, KTH Royal Institute of Technology, SE 106 91 Stockholm, Sweden
    Hippocampus 23:87-99. 2013
  8. ncbi Dampening of hyperexcitability in CA1 pyramidal neurons by polyunsaturated fatty acids acting on voltage-gated ion channels
    Jenny Tigerholm
    Department of Computational Biology, School of Computer Science and Communication, KTH Royal Institute of Technology, Stockholm, Sweden
    PLoS ONE 7:e44388. 2012

Collaborators

Detail Information

Publications8

  1. ncbi Ionic mechanisms in the generation of subthreshold oscillations and action potential clustering in entorhinal layer II stellate neurons
    Erik Fransen
    Department of Numerical Analysis and Computer Science, Royal Institute of Technology, Stockholm, Sweden
    Hippocampus 14:368-84. 2004
    ..The model also predicts that the fast component of Ih is responsible for the involvement in the generation of subthreshold oscillations, and the slow component dominates in the generation of spike clusters...
  2. ncbi Functional role of entorhinal cortex in working memory processing
    Erik Fransen
    Department of Numerical Analysis and Computer Science, Royal Institute of Technology, SE 10044 Stockholm, Sweden
    Neural Netw 18:1141-9. 2005
    ..In both cases, we discuss how cationic currents might be involved and relate their kinetics and pharmacology to behavioral and cellular experimental results...
  3. ncbi Mechanism of graded persistent cellular activity of entorhinal cortex layer v neurons
    Erik Fransen
    School of Computer Science and Communication, Royal Institute of Technology, SE 100 44 Stockholm, Sweden
    Neuron 49:735-46. 2006
    ..The model is consistent with detailed experimental observations and provides a mechanism for maintenance of memory-related activity in individual neurons...
  4. ncbi Simulations of the role of the muscarinic-activated calcium-sensitive nonspecific cation current INCM in entorhinal neuronal activity during delayed matching tasks
    Erik Fransen
    Department of Numerical Analysis and Computer Science, Royal Institute of Technology, S-100 44 Stockholm, Sweden
    J Neurosci 22:1081-97. 2002
    ....
  5. ncbi Reversing nerve cell pathology by optimizing modulatory action on target ion channels
    Jenny Tigerholm
    Department of Computational Biology, School of Computer Science and Communication, Royal Institute of Technology, Stockholm, Sweden
    Biophys J 101:1871-9. 2011
    ..We suggest that the optimization procedure can be used not only for neurons, but also for other organs with excitable cells, such as the heart and pancreas where channelopathies are found...
  6. ncbi Role of A-type potassium currents in excitability, network synchronicity, and epilepsy
    Erik Fransen
    Department of Computational Biology, School of Computer Science and Communication, Royal Institute of Technology, AlbaNova University Center, Stockholm, Sweden
    Hippocampus 20:877-87. 2010
    ..Wealso suggest that compounds changing K(A)-kinetics may be used to pharmacologically improve epileptic status...
  7. ncbi Integration of synchronous synaptic input in CA1 pyramidal neuron depends on spatial and temporal distributions of the input
    Jenny Tigerholm
    Department of Computational Biology, School of Computer Science and Communication, KTH Royal Institute of Technology, SE 106 91 Stockholm, Sweden
    Hippocampus 23:87-99. 2013
    ..We suggest that dendritic conductances and their modulatory systems may be part of the regulation of processing of information, in particular for how network synchronicity affects learning and memory...
  8. ncbi Dampening of hyperexcitability in CA1 pyramidal neurons by polyunsaturated fatty acids acting on voltage-gated ion channels
    Jenny Tigerholm
    Department of Computational Biology, School of Computer Science and Communication, KTH Royal Institute of Technology, Stockholm, Sweden
    PLoS ONE 7:e44388. 2012
    ....