M Ridderstrale

Summary

Country: Sweden

Publications

  1. ncbi Differential phosphorylation of Janus kinase 2, Stat5A and Stat5B in response to growth hormone in primary rat adipocytes
    M Ridderstrale
    Department of Endocrinology, Lund University, Wallenberglaboratory, University Hospital Malmo, S 205 02 Malmo, Sweden
    Mol Cell Endocrinol 183:49-54. 2001
  2. ncbi [A case report. Rosiglitazone treatment was highly effective yet had to be terminated]
    Martin Ridderstrale
    Endokrinologiska kliniken, Universitetssjukhuset MAS, Malmo
    Lakartidningen 99:407-10. 2002
  3. ncbi FOXC2 mRNA Expression and a 5' untranslated region polymorphism of the gene are associated with insulin resistance
    Martin Ridderstrale
    Department of Endocrinology, Lund University, Wallenberg Laboratory, University Hospital Malmo, S 205 02 Malmo, Sweden
    Diabetes 51:3554-60. 2002
  4. ncbi Calpain 10 and type 2 diabetes: are we getting closer to an explanation?
    Martin Ridderstrale
    Department of Clinical Sciences, Lund University, Wallenberg Laboratory, University Hospital MAS, S 205 02 Malmo, Sweden
    Curr Opin Clin Nutr Metab Care 8:361-6. 2005
  5. ncbi SOCS-3 is involved in the downregulation of the acute insulin-like effects of growth hormone in rat adipocytes by inhibition of Jak2/IRS-1 signaling
    M Ridderstrale
    Department of Endocrinology, Lund University, Wallenberg Laboratory, University Hospital Malmo, Malmo, Sweden
    Horm Metab Res 35:169-77. 2003
  6. ncbi Signaling mechanism for the insulin-like effects of growth hormone--another example of a classical hormonal negative feedback loop
    Martin Ridderstrale
    Department of Endocrinology, Lund University, University Hospital MAS, S 205 02 Malmo, Sweden
    Curr Drug Targets Immune Endocr Metabol Disord 5:79-92. 2005
  7. ncbi Role of the FOXC2 -512C>T polymorphism in type 2 diabetes: possible association with the dysmetabolic syndrome
    E Carlsson
    Department of Endocrinology, Lund University, University Hospital MAS, Malmo, Sweden
    Int J Obes (Lond) 29:268-74. 2005
  8. ncbi The hormone-sensitive lipase C-60G promoter polymorphism is associated with increased waist circumference in normal-weight subjects
    E Carlsson
    Department of Clinical Sciences, Diabetes and Endocrinology, Malmo University Hospital, Lund University, Sweden
    Int J Obes (Lond) 30:1442-8. 2006
  9. ncbi A polymorphism in the adiponectin gene influences adiponectin expression levels in visceral fat in obese subjects
    J Fredriksson
    Department of Clinical Sciences Diabetes and Endocrinology, Malmo University Hospital, Lund University, Wallenberg Laboratory, Malmo, Sweden
    Int J Obes (Lond) 30:226-32. 2006
  10. ncbi Characterization of the human skeletal muscle glycogen synthase gene (GYS1) promoter
    J Fredriksson
    Malmo University Hospital, Malmo, Sweden
    Eur J Clin Invest 34:113-21. 2004

Detail Information

Publications13

  1. ncbi Differential phosphorylation of Janus kinase 2, Stat5A and Stat5B in response to growth hormone in primary rat adipocytes
    M Ridderstrale
    Department of Endocrinology, Lund University, Wallenberglaboratory, University Hospital Malmo, S 205 02 Malmo, Sweden
    Mol Cell Endocrinol 183:49-54. 2001
    ..We conclude that Stat5A is important for the diabetogenic actions of GH and that Jak2 still is the most probable candidate kinase for Stat5A in primary adipocytes...
  2. ncbi [A case report. Rosiglitazone treatment was highly effective yet had to be terminated]
    Martin Ridderstrale
    Endokrinologiska kliniken, Universitetssjukhuset MAS, Malmo
    Lakartidningen 99:407-10. 2002
    ..4 to 5.3%. In spite of this dramatic effect on glucose homeostasis administration of the drug had to be discontinued due to critical congestive heart failure...
  3. ncbi FOXC2 mRNA Expression and a 5' untranslated region polymorphism of the gene are associated with insulin resistance
    Martin Ridderstrale
    Department of Endocrinology, Lund University, Wallenberg Laboratory, University Hospital Malmo, S 205 02 Malmo, Sweden
    Diabetes 51:3554-60. 2002
    ..03 vs. P = 0.7). Our data suggest that increased FOXC2 expression may protect against insulin resistance in human subjects and that genetic variability in the gene may influence features associated with the metabolic syndrome...
  4. ncbi Calpain 10 and type 2 diabetes: are we getting closer to an explanation?
    Martin Ridderstrale
    Department of Clinical Sciences, Lund University, Wallenberg Laboratory, University Hospital MAS, S 205 02 Malmo, Sweden
    Curr Opin Clin Nutr Metab Care 8:361-6. 2005
    ..In this paper we give a general background on the genetic studies performed on CAPN10 to date, and review the most recent studies on the functional role of calpain 10...
  5. ncbi SOCS-3 is involved in the downregulation of the acute insulin-like effects of growth hormone in rat adipocytes by inhibition of Jak2/IRS-1 signaling
    M Ridderstrale
    Department of Endocrinology, Lund University, Wallenberg Laboratory, University Hospital Malmo, Malmo, Sweden
    Horm Metab Res 35:169-77. 2003
    ....
  6. ncbi Signaling mechanism for the insulin-like effects of growth hormone--another example of a classical hormonal negative feedback loop
    Martin Ridderstrale
    Department of Endocrinology, Lund University, University Hospital MAS, S 205 02 Malmo, Sweden
    Curr Drug Targets Immune Endocr Metabol Disord 5:79-92. 2005
    ....
  7. ncbi Role of the FOXC2 -512C>T polymorphism in type 2 diabetes: possible association with the dysmetabolic syndrome
    E Carlsson
    Department of Endocrinology, Lund University, University Hospital MAS, Malmo, Sweden
    Int J Obes (Lond) 29:268-74. 2005
    ..Here, we addressed the potential role for FOXC2 as a candidate gene for type 2 diabetes and associated phenotypes...
  8. ncbi The hormone-sensitive lipase C-60G promoter polymorphism is associated with increased waist circumference in normal-weight subjects
    E Carlsson
    Department of Clinical Sciences, Diabetes and Endocrinology, Malmo University Hospital, Lund University, Sweden
    Int J Obes (Lond) 30:1442-8. 2006
    ..The aim of the present study was to investigate the role of the HSL gene promoter variant C-60G, a polymorphism which previously has been associated with reduced promoter activity in vitro, in obesity and type 2 diabetes...
  9. ncbi A polymorphism in the adiponectin gene influences adiponectin expression levels in visceral fat in obese subjects
    J Fredriksson
    Department of Clinical Sciences Diabetes and Endocrinology, Malmo University Hospital, Lund University, Wallenberg Laboratory, Malmo, Sweden
    Int J Obes (Lond) 30:226-32. 2006
    ..Reduced serum adiponectin levels have been found in obesity and type 2 diabetes and variations in the adiponectin gene (APM1) have been associated with type 2 diabetes and features of the metabolic syndrome in different populations...
  10. ncbi Characterization of the human skeletal muscle glycogen synthase gene (GYS1) promoter
    J Fredriksson
    Malmo University Hospital, Malmo, Sweden
    Eur J Clin Invest 34:113-21. 2004
    ..Therefore we studied transcriptional regulation of the human skeletal muscle glycogen synthase gene (GYS1) and evaluated the effects of insulin and forskolin on the promoter activity...
  11. ncbi Obesity and cardiovascular risk factors in type 2 diabetes: results from the Swedish National Diabetes Register
    M Ridderstrale
    Department of Clinical Sciences, Clinical Obesity, Lund University, Wallenberg Laboratory, University Hospital, Malmo, Sweden
    J Intern Med 259:314-22. 2006
    ..To compare obese with normal and overweight type 2 diabetic patients regarding body mass index (BMI) and cardiovascular risk factors, and to analyse changes in weight versus risk factors...
  12. ncbi Characterization of a naturally occurring mutation (L107I) in the HNF1 alpha (MODY3) gene
    C Cervin
    Department of Endocrinology, Wallenberg Laboratory, Malmo University Hospital, Sweden
    Diabetologia 45:1703-8. 2002
    ..In this study we have examined the in vivo and in vitro effects of a mutation (L107I) outside the DNA binding and dimerization domains in the N terminal part of the HNF1 alpha gene...
  13. ncbi Increased risk of obesity associated with the variant allele of the PPARGC1A Gly482Ser polymorphism in physically inactive elderly men
    M Ridderstrale
    Department of Clinical Sciences Clinical Obesity, Malmo University Hospital, Lund University, S 205 02 Malmo, Sweden
    Diabetologia 49:496-500. 2006
    ..Previous studies indicate that these risks depend on sex and environmental triggers such as age. The aim of the present study was to investigate the possible interactions between genotype and age and physical activity on risk of obesity...