Alexander Panossian

Summary

Country: Sweden

Publications

  1. doi request reprint Pharmacology of Schisandra chinensis Bail.: an overview of Russian research and uses in medicine
    Alexander Panossian
    Swedish Herbal Institute Research and Development, Spårvägen 2, SE 432 96 Askloster, Sweden
    J Ethnopharmacol 118:183-212. 2008
  2. doi request reprint Pharmacokinetic and pharmacodynamic study of interaction of Rhodiola rosea SHR-5 extract with warfarin and theophylline in rats
    Alexander Panossian
    Swedish Herbal Institute Research and Development, Askloster, Sweden
    Phytother Res 23:351-7. 2009
  3. doi request reprint Adaptogens exert a stress-protective effect by modulation of expression of molecular chaperones
    Alexander Panossian
    SHI Research and Development, Spårvägen 2, SE 432 96 Askloster, Sweden
    Phytomedicine 16:617-22. 2009
  4. ncbi request reprint Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity
    Alexander Panossian
    Swedish Herbal Institute Research and Development, Spårvägen 2, SE 43296 Askloster, Sweden
    Curr Clin Pharmacol 4:198-219. 2009
  5. doi request reprint Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy
    A Panossian
    Swedish Herbal Institute Research and Development, Askloster, Sweden
    Phytomedicine 17:481-93. 2010
  6. pmc The Adaptogens Rhodiola and Schizandra Modify the Response to Immobilization Stress in Rabbits by Suppressing the Increase of Phosphorylated Stress-activated Protein Kinase, Nitric Oxide and Cortisol
    Alexander Panossian
    Swedish Herbal Institute Research and Development, Spårvägen 2, Åsklöster 43296, Sweden
    Drug Target Insights 2:39-54. 2007
  7. pmc Adaptogens stimulate neuropeptide y and hsp72 expression and release in neuroglia cells
    Alexander Panossian
    Department of Research and Development, Swedish Herbal Institute Research and Development Åskloster, Sweden
    Front Neurosci 6:6. 2012
  8. pmc Synergy and Antagonism of Active Constituents of ADAPT-232 on Transcriptional Level of Metabolic Regulation of Isolated Neuroglial Cells
    Alexander Panossian
    Swedish Herbal Institute Research and Development Göteborg, Sweden
    Front Neurosci 7:16. 2013

Detail Information

Publications8

  1. doi request reprint Pharmacology of Schisandra chinensis Bail.: an overview of Russian research and uses in medicine
    Alexander Panossian
    Swedish Herbal Institute Research and Development, Spårvägen 2, SE 432 96 Askloster, Sweden
    J Ethnopharmacol 118:183-212. 2008
    ....
  2. doi request reprint Pharmacokinetic and pharmacodynamic study of interaction of Rhodiola rosea SHR-5 extract with warfarin and theophylline in rats
    Alexander Panossian
    Swedish Herbal Institute Research and Development, Askloster, Sweden
    Phytother Res 23:351-7. 2009
    ..It is concluded that SHR-5 might be of value in the treatment of patients with mild or moderate depression, and that its interaction with co-administered drugs is likely to be negligible...
  3. doi request reprint Adaptogens exert a stress-protective effect by modulation of expression of molecular chaperones
    Alexander Panossian
    SHI Research and Development, Spårvägen 2, SE 432 96 Askloster, Sweden
    Phytomedicine 16:617-22. 2009
    ..Our studies suggest that this could be one of the mechanisms of action of plant adaptogens...
  4. ncbi request reprint Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity
    Alexander Panossian
    Swedish Herbal Institute Research and Development, Spårvägen 2, SE 43296 Askloster, Sweden
    Curr Clin Pharmacol 4:198-219. 2009
    ..Adaptogen-induced up-regulation of Hsp70 triggers stress-induced JNK-1 and DAF-16-mediated pathways regulating the resistance to stress and resulting in enhanced mental and physical performance and, possibly, increased longevity...
  5. doi request reprint Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy
    A Panossian
    Swedish Herbal Institute Research and Development, Askloster, Sweden
    Phytomedicine 17:481-93. 2010
    ..In conclusion, Rhodiola rosea has robust traditional and pharmacological evidence of use in fatigue, and emerging evidence supporting cognition and mood...
  6. pmc The Adaptogens Rhodiola and Schizandra Modify the Response to Immobilization Stress in Rabbits by Suppressing the Increase of Phosphorylated Stress-activated Protein Kinase, Nitric Oxide and Cortisol
    Alexander Panossian
    Swedish Herbal Institute Research and Development, Spårvägen 2, Åsklöster 43296, Sweden
    Drug Target Insights 2:39-54. 2007
    ..It is suggested that the inhibitory effects of R. rosea and S. chinensis on p-SAPK/p-JNK activation may be associated with their antidepressant activity as well as their positive effects on mental performance under stress...
  7. pmc Adaptogens stimulate neuropeptide y and hsp72 expression and release in neuroglia cells
    Alexander Panossian
    Department of Research and Development, Swedish Herbal Institute Research and Development Åskloster, Sweden
    Front Neurosci 6:6. 2012
    ....
  8. pmc Synergy and Antagonism of Active Constituents of ADAPT-232 on Transcriptional Level of Metabolic Regulation of Isolated Neuroglial Cells
    Alexander Panossian
    Swedish Herbal Institute Research and Development Göteborg, Sweden
    Front Neurosci 7:16. 2013
    ..Presumably, this phenomenon could be used to eliminate undesirable effects (e.g., toxic effects) and increase the selectivity of pharmacological intervention...