Research Topics
| Svante OstlingSummaryCountry: Sweden Publications
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Publications
The incidence of first-onset psychotic symptoms and paranoid ideation in a representative population sample followed from age 70-90 years. Relation to mortality and later development of dementiaS Ostling
The Sahlgrenska Academy at Goteborg University, Institute of Clinical Neuroscience and Physiology, Psychiatry Section, Unit of Epidemiology, Sahlgrenska University Hospital, Goteborg, Sweden
Int J Geriatr Psychiatry 22:520-8. 2007..Limited data are available on the incidence of psychotic symptoms in the elderly...
Psychotic and behavioural symptoms in a population-based sample of the very elderly subjectsS Ostling
Sahlgrenska Academy, University of Gothenburg, Goteborg, Sweden
Acta Psychiatr Scand 120:147-52. 2009..The aim was to elucidate the relationship between psychotic and behavioural symptoms in the elderly...
Psychotic symptoms and paranoid ideation in a nondemented population-based sample of the very oldSvante Ostling
Goteborg University, Institute of Clinical Neuroscience, Psychiatry Section, Sahlgrenska University Hospital S, SE 413 45 Goteborg, Sweden
Arch Gen Psychiatry 59:53-9. 2002..Psychotic symptoms are reported to be uncommon in the elderly, and may be underrated in traditional epidemiological studies...
Psychotic symptoms in a population-based sample of 85-year-old individuals with dementiaSvante Ostling
The Sahlgrenska Academy at Gothenburg University, Institute of Clinical Neuroscience and Physiology, Sahlgrenska University Hospital, Sweden
J Geriatr Psychiatry Neurol 24:3-8. 2011..This finding of a high proportion of psychotic symptoms also in individuals with mild severity of VaD should alert health professionals to evaluate dementia in very old patients who present with hallucinations or delusions...
Basal ganglia calcification and psychotic symptoms in the very oldSvante Ostling
The Sahlgrenska Academy at Goteborg University, Institute of Clinical Neuroscience, Psychiatry Section, Unit for Neuropsychiatric Epidemiology, Sahlgrenska University Hospital, Goteborg, Sweden
Int J Geriatr Psychiatry 18:983-7. 2003..Basal ganglia calcification (BGC) is associated with psychotic symptoms in young and middle-aged patient samples...
Cognitive test performance in relation to psychotic symptoms and paranoid ideation in non-demented 85-year-oldsS Ostling
Sahlgrenska Academy at Goteborg University, Institute of Clinical Neuroscience, Sweden
Psychol Med 34:443-50. 2004..However, it is not clear whether this finding would be observed in general population samples of non-demented elderly, particularly after adjustment for potential confounding factors...
Psychotic symptoms and paranoid ideation in a population-based sample of 95-year-oldsSvante Ostling
Sahlgrenska Academy at Goteborg University, Institute of Neuroscience and Physiology, Psychiatry, and Neurochemistry Section, Sahlgrenska University Hospital, Goteborg, Sweden
Am J Geriatr Psychiatry 15:999-1004. 2007..To examine the 1-year prevalence of psychotic symptoms and schizophrenia in nondemented 95-year-olds, and to examine the relation between psychotic symptoms and other psychiatric symptoms, sensory impairments, and cognitive functioning...
Nonlinear blood pressure effects on cognition in old age: separating between-person and within-person associationsValgeir Thorvaldsson
Department of Psychology, University of Gothenburg, Gothenburg, Sweden
Psychol Aging 27:375-83. 2012..Notably, between-person and within-person estimates did not reveal similar associations, suggesting the need to separate the two effects in the analysis of associations between BP and cognition in old age...
Midlife homocysteine and late-life dementia in women. A prospective population studyDimitri E Zylberstein
Sahlgrenska School of Public Health and Community Medicine, University of Gothenburg, Sweden
Neurobiol Aging 32:380-6. 2011..Kaplan-Meier plots showed divergence with respect to dementia after 22 years of follow-up. In conclusion, high homocysteine in midlife is an independent risk factor for the development of late-life Alzheimer dementia in women...
The prevalence of psychotic symptoms and paranoid ideation in non-demented population samples aged 70-82 yearsRobert Sigström
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at University of Gothenburg, Sweden
Int J Geriatr Psychiatry 24:1413-9. 2009..Psychotic symptoms may be less prevalent among younger elderly. We examined the prevalence of psychotic symptoms in a population-based sample of non-demented elderly aged 70-82 years...
The 1-month prevalence of generalized anxiety disorder according to DSM-IV, DSM-V, and ICD-10 among nondemented 75-year-olds in Gothenburg, SwedenJohan Nilsson
Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Am J Geriatr Psychiatry 20:963-72. 2012..We also aimed to examine comorbidity between GAD and other psychiatric diagnoses, such as depression...
Leptin and dementia over 32 years-The Prospective Population Study of WomenDeborah R Gustafson
Section for Psychiatry and Neurochemistry, Neuropsychiatric Epidemiology Unit at the Sahlgrenska Academy, University of Gothenburg, Sweden
Alzheimers Dement 8:272-7. 2012..We explored the relationship between serum leptin in mid-life and dementia, which is a late-life outcome...
Blood pressure trajectories from midlife to late life in relation to dementia in women followed for 37 yearsErik Joas
Department of Neurochemistry and Psychiatry, Neuropsychiatric Epidemiology Unit, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Hypertension 59:796-801. 2012..Whether the trajectory of blood pressure is a risk factor or part of the clinical course of dementia needs to be elucidated...
A population-based study on phobic fears and DSM-IV specific phobia in 70-year oldsRobert Sigström
Department of Psychiatry and Neurochemistry, Neuropsychiatric Epidemiology Unit, Institute of Neuroscience and Physiology, University of Gothenburg, Molndal, Sweden
J Anxiety Disord 25:148-53. 2011..SP was related to lower global functioning. We conclude that specific phobia in the elderly should receive attention from health professionals as it is common and associated with a decrease in global functioning...
Attempted suicide in the elderly: characteristics of suicide attempters 70 years and older and a general population comparison groupStefan Wiktorsson
Department of Psychiatry and Neurochemistry, Neuropshychiatric Epidemiology Unit, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Stockholm, Sweden
Am J Geriatr Psychiatry 18:57-67. 2010..To identify factors associated with attempted suicide in the elderly...
The pattern of cognitive symptoms predicts time to dementia onsetSimona Sacuiu
Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Molndal, Sweden
Alzheimers Dement 5:199-206. 2009..Our objective was to investigate whether different patterns of cognitive symptoms at ages 70, 75, and 79 years predict short-term (< or =5 years) and long-term (>5 years) dementia onset...
Onset and rate of cognitive change before dementia diagnosis: findings from two Swedish population-based longitudinal studiesValgeir Thorvaldsson
Department of Psychology, University of Gothenburg, Gothenburg, Sweden
J Int Neuropsychol Soc 17:154-62. 2011..Onset occurred later and acceleration was greater in crystallized abilities, suggesting that those markers may provide more valid identification of cases in later stages of the prodromal phase...
Prevalence of social phobia in non-demented elderly from a swedish population studyBjörn Karlsson
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden
Am J Geriatr Psychiatry 17:127-35. 2009....
Midlife respiratory function and Incidence of Alzheimer's disease: a 29-year longitudinal study in womenXinxin Guo
Neuropsychiatric Epidemiology Unit, Institute of Clinical Neurosciences, Sahlgrenska Academy at Goteborg University, SE 413 45 Goteborg, Sweden
Neurobiol Aging 28:343-50. 2007..94), 0.71 (0.54-0.95) and 0.74 (0.56-0.98), respectively, after adjustment for potential confounders. These data reinforce the advantages of maintaining good respiratory function in midlife, even though causation cannot be established...
One-month prevalence of mental disorders in a population sample of 95-year oldsAnne Börjesson-Hanson
Department of Psychiatry and Neurochemistry, Neuropsychiatry Epidemiology Unit, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Am J Geriatr Psychiatry 19:284-91. 2011..To determine the 1-month prevalence of mental disorders among 95-year olds...
37 years of body mass index and dementia: observations from the prospective population study of women in Gothenburg, SwedenDeborah R Gustafson
Department of Neurochemistry and Psychiatry, Neuropsychiatric Epidemiology Unit, at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
J Alzheimers Dis 28:163-71. 2012..BMI may be a potential marker of dementia-related neuropathologies in the brain. Dementia is related to a common risk factor, BMI, from mid-to late-life...
Depression in Swedish women: relationship to factors at birthPia Gudmundsson
Institute of Neuroscience and Physiology, Section for Psychiatry and Neurochemistry, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Eur J Epidemiol 26:55-60. 2011..Lower than median birth weights and shorter gestational time were related to lifetime depression in women. Both neurodevelopmental and environmental contributions to lifetime depression may be considered...
Midlife psychological stress and risk of dementia: a 35-year longitudinal population studyLena Johansson
Department of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, 43141 Mölndal, Sweden
Brain 133:2217-24. 2010..More studies are needed to confirm our findings and to study potential neurobiological mechanisms of these associations...
Secular changes in cognitive predictors of dementia and mortality in 70-year-oldsS Sacuiu
Department of Psychiatry and Neurochemistry, Unit of Psychiatric Epidemiology, University of Gothenburg and Sahlgrenska University Hospital, Institute of Neuroscience and Physiology, Wallinsgatan 6, 431 41 Mölndal, Sweden
Neurology 75:779-85. 2010..Successive elderly birth cohorts improved in cognitive performance during the 20th century. It is not clear whether this influences cognitive predictors of dementia and mortality...
Adiposity indicators and dementia over 32 years in SwedenD R Gustafson
Section for Psychiatry and Neurochemistry, Neuropsychiatric Epidemiology Unit, Sahlgrenska Academy, University of Gothenburg, Sweden
Neurology 73:1559-66. 2009..Late-life decrease in body mass index (BMI) or body weight within several years of a dementia diagnosis has also been reported. Differences in study designs and analyses may provide different pictures of this relationship...
Temporal lobe atrophy and white matter lesions are related to major depression over 5 years in the elderlyPernille J Olesen
Neuropsychiatric Epidemiology Unit, Section for Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Molndal, Sweden
Neuropsychopharmacology 35:2638-45. 2010..This may have implications for prevention, as both neurodegeneration and cerebrovascular disease have been related to preventable factors...
The prognosis and incidence of social phobia in an elderly population. A 5-year follow-upB Karlsson
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden
Acta Psychiatr Scand 122:4-10. 2010..To examine the prognosis and incidence of social fears and phobia in an elderly population sample followed for 5 years...
Paranoid symptoms and hallucinations among the older people in Western EuropeSvante Ostling
Institute of Neuroscience and Physiology, Psychiatry Section, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Int J Geriatr Psychiatry 28:573-9. 2013..It is not clear whether the prevalence of psychosis increases with age. We studied the age-specific prevalence of psychotic symptoms in older people in Western Europe...
Biological correlates of clinical subgroups of Alzheimer's diseaseMagnus Sjogren
Institute of Clinical Neuroscience, Goteborg University, Goteborg, Sweden
Dement Geriatr Cogn Disord 14:191-7. 2002..For instance, a decreased CSF level of HVA (p < 0.001) was specific to AD type I and decreased rCBF (p < 0.05 to <0.001) in three particular regions was specific to AD type II...
Alcoholic beverages and incidence of dementia: 34-year follow-up of the prospective population study of women in GoteborgK Mehlig
Department of Public Health and Community Medicine Primary Health Care, Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
Am J Epidemiol 167:684-91. 2008..Because a protective effect was not seen for the other beverages, at least part of the association for wine may be explained by components other than ethanol...
The incidence of first-onset depression in a population followed from the age of 70 to 85S P Pálsson
Institute of Clinical Neuroscience, Department of Psychiatry, Sahlgrenska University Hospital, Goteborg University, Sweden
Psychol Med 31:1159-68. 2001..Due to the limited data available, it is not clear whether the incidence of first-onset depression varies with age in the elderly...
Suicidal feelings in a population sample of nondemented 85-year-oldsI Skoog
Department of Psychiatry, Sahlgrenska Hospital, Goteborg University, Sweden
Am J Psychiatry 153:1015-20. 1996..The authors studied the 1-month frequency of suicidal feelings among very old people...
Diagnostic criteria influence dementia prevalenceJohannes Wancata
Medical University of Vienna, Department of Psychiatry, Vienna, Austria
Am J Geriatr Psychiatry 15:1034-45. 2007....
