G Olivecrona

Summary

Country: Sweden

Publications

  1. ncbi request reprint Apolipoprotein CII from chicken (Gallus domesticus). The amino-terminal domain is different from corresponding domains in mammals
    Y Andersson
    Department of Medical Biochemistry and Biophysics, Umea University, S 901 87 Umea, Sweden
    J Biol Chem 271:33060-6. 1996
  2. ncbi request reprint Lipid binding of apolipoprotein CII is required for stimulation of lipoprotein lipase activity against apolipoprotein CII-deficient chylomicrons
    G Olivecrona
    Department of Medical Biochemistry and Biophysics, Umea University, Sweden
    Arterioscler Thromb Vasc Biol 17:1545-9. 1997
  3. ncbi request reprint Clearance of artificial triacylglycerol particles
    G Olivecrona
    Department of Medical Biochemistry and Biophysics, University of Umea, Sweden
    Curr Opin Clin Nutr Metab Care 1:143-51. 1998
  4. ncbi request reprint Protease inhibitors, the responsible components for the serum-dependent enhancement of Actinobacillus actinomycetemcomitans leukotoxicity
    A Johansson
    Department of Odontology, Umea University, Sweden
    Eur J Oral Sci 109:335-41. 2001
  5. ncbi request reprint Lipoprotein lipase during continuous heparin infusion: tissue stores become partially depleted
    B Nasstrom
    Division of Nephrology, Department of Internal Medicine, Umea University, Sweden
    J Lab Clin Med 138:206-13. 2001
  6. ncbi request reprint Global structure and dynamics of human apolipoprotein CII in complex with micelles: evidence for increased mobility of the helix involved in the activation of lipoprotein lipase
    J Zdunek
    Department of Medical Biochemistry and Biophysics and Medical Biosciences, Physiological Chemistry, Umea University, SE 901 87 Umea, Sweden
    Biochemistry 42:1872-89. 2003
  7. ncbi request reprint Apolipoprotein CII from rainbow trout (Oncorhynchus mykiss) is functionally active but structurally very different from mammalian apolipoprotein CII
    Y Shen
    Department of Medical Biosciences, Medical Biochemistry, Umea University, Umea, Sweden
    Gene 254:189-98. 2000
  8. ncbi request reprint Effects of the heparin-mimicking compound RG-13577 on lipoprotein lipase and on lipase mediated binding of LDL to cells
    L Neuger
    Department of Medical Biosciences, Umea University, SE 901 87 Umea, Sweden
    Atherosclerosis 157:13-21. 2001
  9. ncbi request reprint Interactions of lipoprotein lipase with the active-site inhibitor tetrahydrolipstatin (Orlistat)
    A Lookene
    Department of Medical Biochemistry and Biophysics, University of Umea, Sweden
    Eur J Biochem 222:395-403. 1994
  10. ncbi request reprint Lipoprotein lipase activity/mass ratio is higher in omental than in subcutaneous adipose tissue
    T Ruge
    Department of Public Health, Umea University, Umea, Sweden
    Eur J Clin Invest 36:16-21. 2006

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Apolipoprotein CII from chicken (Gallus domesticus). The amino-terminal domain is different from corresponding domains in mammals
    Y Andersson
    Department of Medical Biochemistry and Biophysics, Umea University, S 901 87 Umea, Sweden
    J Biol Chem 271:33060-6. 1996
    ..Secondary structure prediction showed that the amino-terminal domain could form two amphipathic alpha-helices in almost similar areas of the sequence as was previously predicted for human apoCII...
  2. ncbi request reprint Lipid binding of apolipoprotein CII is required for stimulation of lipoprotein lipase activity against apolipoprotein CII-deficient chylomicrons
    G Olivecrona
    Department of Medical Biochemistry and Biophysics, Umea University, Sweden
    Arterioscler Thromb Vasc Biol 17:1545-9. 1997
    ..This idea is in accord with previous studies with lipid monolayers, which showed that the lipid-binding part is necessary for activation of the enzyme at high surface pressures...
  3. ncbi request reprint Clearance of artificial triacylglycerol particles
    G Olivecrona
    Department of Medical Biochemistry and Biophysics, University of Umea, Sweden
    Curr Opin Clin Nutr Metab Care 1:143-51. 1998
    ..In contrast, many of the larger particles are removed by other, less well defined, mechanisms...
  4. ncbi request reprint Protease inhibitors, the responsible components for the serum-dependent enhancement of Actinobacillus actinomycetemcomitans leukotoxicity
    A Johansson
    Department of Odontology, Umea University, Sweden
    Eur J Oral Sci 109:335-41. 2001
    ..The degradation is caused by enzymes from degranulated PMNL triggered by leukotoxin...
  5. ncbi request reprint Lipoprotein lipase during continuous heparin infusion: tissue stores become partially depleted
    B Nasstrom
    Division of Nephrology, Department of Internal Medicine, Umea University, Sweden
    J Lab Clin Med 138:206-13. 2001
    ..After less than 1 hour, the stores of LPL have been exhausted, and recruitment of lipase into plasma depends on a slow but stable delivery of newly synthesized molecules...
  6. ncbi request reprint Global structure and dynamics of human apolipoprotein CII in complex with micelles: evidence for increased mobility of the helix involved in the activation of lipoprotein lipase
    J Zdunek
    Department of Medical Biochemistry and Biophysics and Medical Biosciences, Physiological Chemistry, Umea University, SE 901 87 Umea, Sweden
    Biochemistry 42:1872-89. 2003
    ..The overall structure and the internal dynamics, combined with previous mutation data, give important clues toward a possible mechanism for the activation of LPL by apoCII...
  7. ncbi request reprint Apolipoprotein CII from rainbow trout (Oncorhynchus mykiss) is functionally active but structurally very different from mammalian apolipoprotein CII
    Y Shen
    Department of Medical Biosciences, Medical Biochemistry, Umea University, Umea, Sweden
    Gene 254:189-98. 2000
    ..We conclude that apoCII from rainbow trout is in most parts structurally different from apoCII from other species, and that it is adapted to function at low temperature...
  8. ncbi request reprint Effects of the heparin-mimicking compound RG-13577 on lipoprotein lipase and on lipase mediated binding of LDL to cells
    L Neuger
    Department of Medical Biosciences, Umea University, SE 901 87 Umea, Sweden
    Atherosclerosis 157:13-21. 2001
    ..Lipase-mediated binding and uptake of human LDL in these cells was also prevented by RG-13577. Thus, in the test systems RG-13577 had the same effects as heparin, but on a molar basis RG-13577 was in all cases less effective...
  9. ncbi request reprint Interactions of lipoprotein lipase with the active-site inhibitor tetrahydrolipstatin (Orlistat)
    A Lookene
    Department of Medical Biochemistry and Biophysics, University of Umea, Sweden
    Eur J Biochem 222:395-403. 1994
    ..It is suggested that THL induces local conformational changes in LPL, which may involve opening of the putative surface lid structure which covers the active-site...
  10. ncbi request reprint Lipoprotein lipase activity/mass ratio is higher in omental than in subcutaneous adipose tissue
    T Ruge
    Department of Public Health, Umea University, Umea, Sweden
    Eur J Clin Invest 36:16-21. 2006
    ..Animal experiments indicate that short-term regulation of LPL is mainly post-translational. Different processing of LPL in different AT depots may play a role in the distribution of lipids in the body...
  11. ncbi request reprint Tissue-specific regulation of lipoprotein lipase in humans: effects of fasting
    T Ruge
    Department of Public Health and Clinical Medicine, Umea University, SE 901 87 Umea, Sweden
    Eur J Clin Invest 35:194-200. 2005
    ..This is in contrast to laboratory animals, where the strong down-regulation of LPL in their adipose tissue on fasting is reflected in decreased levels of LPL activity in postheparin plasma...
  12. ncbi request reprint Lipoprotein lipase during heparin infusion: lower activity in hemodialysis patients
    B Nasstrom
    Division of Nephrology, Department of Internal Medicine, Umea University, Sweden
    Scand J Clin Lab Invest 63:45-53. 2003
    ..A contributing factor may be a derangement of the lipoprotein lipase (LPL) system. During dialysis, with heparin as anticoagulant, the enzyme is released into the circulating blood...
  13. ncbi request reprint Apolipoprotein CIII from guinea pig (Cavia porcellus) is shorter and less homologous than apolipoprotein CIII from other mammals
    Y Yin
    Department of Medical Biochemistry and Biophysics, Umea University, Sweden
    Comp Biochem Physiol B Biochem Mol Biol 124:157-61. 1999
    ..Our present study could be helpful for the future elucidation of the structure-function relationships and evolution of apo CIII...
  14. ncbi request reprint Lack of lipoprotein-dependent effects on the cytotoxic interactions of Actinobacillus actinomycetemcomitans leukotoxin with human neutrophils
    A Johansson
    Division of Periodontology, Department of Odontology, Faculty of Medicine and Odontology, Umea University, Umea, Sweden
    APMIS 110:857-62. 2002
    ..The results indicate that the cytotoxic interactions of A. actinomycetemcomitans leukotoxin against human PMNL are not influenced by the presence of serum lipoproteins...