Research Topics
Genomes and Genes | J MelkeSummaryCountry: Sweden Publications
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Publications
Monoamine related functional gene variants and relationships to monoamine metabolite concentrations in CSF of healthy volunteersErik G Jonsson
Department of Clinical Neuroscience, Psychiatry Section, HUBIN project, Karolinska Institutet, Stockholm, Sweden
BMC Psychiatry 4:4. 2004..CSF monoamine metabolite concentrations are partly determined by genetic influences...
Mutation screening of melatonin-related genes in patients with autism spectrum disordersLina Jonsson
Institute of Neuroscience and Physiology, Department of Pharmacology, Gothenburg University, Sweden
BMC Med Genomics 3:10. 2010....
Serotonin transporter gene polymorphisms are associated with anxiety-related personality traits in womenJ Melke
Department of Pharmacology, Goteborg University, Goteborg, Sweden
Am J Med Genet 105:458-63. 2001..In addition, an association was found between the intron 2 polymorphism and one anxiety-related personality trait (somatic anxiety)...
Serotonin transporter gene polymorphisms and platelet [3H] paroxetine binding in premenstrual dysphoriaJ Melke
Department of Pharmacology, Goteborg University, Sweden
Psychoneuroendocrinology 28:446-58. 2003....
A polymorphism in the serotonin receptor 3A (HTR3A) gene and its association with harm avoidance in womenJonas Melke
Departments of Pharmacology, Goteborg University, Goteborg, Sweden
Arch Gen Psychiatry 60:1017-23. 2003..A polymorphism (C178T) in the 5' region of the HTR3A gene has recently been identified and suggested to be of functional importance...
Cytochrome P450 2E1 gene polymorphisms/haplotypes and Parkinson's disease in a Swedish populationH Niazi Shahabi
Department of Pharmacology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
J Neural Transm 116:567-73. 2009..In conclusion, our results display an association between the rs2070676 polymorphism and PD. Additional investigations are needed to elucidate the importance of this polymorphism for the activity of CYP2E1 and PD susceptibility...
Association between a dinucleotide repeat polymorphism of the estrogen receptor alpha gene and personality traits in womenL Westberg
Department of Pharmacology, Goteborg University, Sweden
Mol Psychiatry 8:118-22. 2003..The results suggest that the studied dinucleotide repeat polymorphism of the ER alpha gene may contribute to specific components of personality...
The serotonin reuptake inhibitor fluoxetine reduces sex steroid-related aggression in female rats: an animal model of premenstrual irritability?H P Ho
Department of Pharmacology, Goteborg University, Goteborg, Sweden
Neuropsychopharmacology 24:502-10. 2001..It is suggested that the aggressive behavior displayed by the female Wistar rat in the resident intruder paradigm may serve as an animal model of premenstrual dysphoria...
Association between the estrogen receptor beta gene and age of onset of Parkinson's diseaseL Westberg
Department of Pharmacology, Goteborg University, Goteborg, Sweden
Psychoneuroendocrinology 29:993-8. 2004..2 for having an early onset of PD compared to non-carriers. In conclusion, our results indicate that genetic variation in the estrogen receptor beta gene may influence the age of onset of PD...
Lack of association between the BDNF Val66Met polymorphism and Parkinson's disease in a Swedish populationAnna Håkansson
Ann Neurol 53:823. 2003
Association between a functional polymorphism in the progesterone receptor gene and panic disorder in womenHoi Por Ho
Department of Pharmacology, Goteborg University, P O B 431, SE 405 30 Goteborg, Sweden
Psychoneuroendocrinology 29:1138-41. 2004..5. No differences between groups were observed for the PROGINS polymorphism. In conclusion, these data suggest that the G331A polymorphism in the progesterone receptor gene may influence the risk for panic disorder in women...
Polymorphisms in oestrogen and progesterone receptor genes: possible influence on prolactin levels in womenLars Westberg
Department of Pharmacology, Goteborg University, Goteborg, Sweden
Clin Endocrinol (Oxf) 61:216-23. 2004....
Expression and genetic variability of PCDH11Y, a gene specific to Homo sapiens and candidate for susceptibility to psychiatric disordersChristelle M Durand
Human Genetics and Cognitive Functions, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
Am J Med Genet B Neuropsychiatr Genet 141:67-70. 2006..These findings do not support the role of PCDH11Y, or more generally of a frequent specific Y chromosome, in the susceptibility to these neuropsychiatric disorders...
Serotonin transporter gene polymorphisms: effect on serotonin transporter availability in the brain of suicide attemptersJessica Bah
Department of Pharmacology, Institute of Neuroscience and Physiology, Sahlgrenska Academy at Goteborg University, Sweden
Psychiatry Res 162:221-9. 2008..Data suggest that polymorphisms in SLC6A4 may influence the expression of the brain serotonin transporter in suicide attempters...
Association between a polymorphism of the 5-HT2C receptor and weight loss in teenage girlsLars Westberg
Department of Pharmacology, Goteborg University, Goteborg, Sweden
Neuropsychopharmacology 26:789-93. 2002..The results support the notion that the studied gene may be involved in the regulation of food intake in young women...
Angiotensin-related genes in patients with panic disorderMarie Olsson
Department of Pharmacology, Goteborg University, Gothenburg, Sweden
Am J Med Genet B Neuropsychiatr Genet 127:81-4. 2004..005), but not female, panic disorder patients than in controls. The results of this investigation provide preliminary evidence for the suggestion that angiotensin-related genes may be associated with panic disorder in men...
