Richard Lundmark

Summary

Country: Sweden

Publications

  1. pmc Arf family GTP loading is activated by, and generates, positive membrane curvature
    Richard Lundmark
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH, UK
    Biochem J 414:189-94. 2008
  2. doi request reprint Driving membrane curvature in clathrin-dependent and clathrin-independent endocytosis
    Richard Lundmark
    Department of Medical Biochemistry and Biophysics, Umea University, 901 87 Umea, Sweden
    Semin Cell Dev Biol 21:363-70. 2010
  3. doi request reprint GRAF1-dependent endocytosis
    Gary J Doherty
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK
    Biochem Soc Trans 37:1061-5. 2009
  4. pmc The GTPase-activating protein GRAF1 regulates the CLIC/GEEC endocytic pathway
    Richard Lundmark
    Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH, UK
    Curr Biol 18:1802-8. 2008
  5. ncbi request reprint Regulated membrane recruitment of dynamin-2 mediated by sorting nexin 9
    Richard Lundmark
    Department of Medical Biochemistry and Biophysics, Umea University, S 901 87 Umea, Sweden
    J Biol Chem 279:42694-702. 2004
  6. pmc The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading
    Gary J Doherty
    MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom
    Mol Biol Cell 22:4380-9. 2011
  7. pmc EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization
    Björn Morén
    Medical Biochemistry and Biophysics, Laboratory for Molecular Infection Medicine, Sweden, Umea University, Umea, Sweden
    Mol Biol Cell 23:1316-29. 2012
  8. ncbi request reprint Expression and properties of sorting nexin 9 in dynamin-mediated endocytosis
    Richard Lundmark
    Department of Medical Biochemistry and Biophysics, Umea University, Sweden
    Methods Enzymol 404:545-56. 2005
  9. doi request reprint SNX9 - a prelude to vesicle release
    Richard Lundmark
    Department of Medical Biochemistry and Biophysics, Umea University, S 90187 Umea, Sweden
    J Cell Sci 122:5-11. 2009
  10. doi request reprint SNX18 is an SNX9 paralog that acts as a membrane tubulator in AP-1-positive endosomal trafficking
    Karin Håberg
    Department of Medical Biochemistry and Biophysics, Umea University, Umea, Sweden
    J Cell Sci 121:1495-505. 2008

Collaborators

Detail Information

Publications13

  1. pmc Arf family GTP loading is activated by, and generates, positive membrane curvature
    Richard Lundmark
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH, UK
    Biochem J 414:189-94. 2008
    ..Arf1 and Arf6 were shown to load GTP in a membrane-curvature-dependent manner and stabilize, or further facilitate, changes in membrane curvature through the insertion of an amphipathic helix...
  2. doi request reprint Driving membrane curvature in clathrin-dependent and clathrin-independent endocytosis
    Richard Lundmark
    Department of Medical Biochemistry and Biophysics, Umea University, 901 87 Umea, Sweden
    Semin Cell Dev Biol 21:363-70. 2010
    ..We will discuss these principles and their implications, focusing on clathrin-dependent and -independent carrier formation and the proteins involved in the respective pathways...
  3. doi request reprint GRAF1-dependent endocytosis
    Gary J Doherty
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK
    Biochem Soc Trans 37:1061-5. 2009
    ....
  4. pmc The GTPase-activating protein GRAF1 regulates the CLIC/GEEC endocytic pathway
    Richard Lundmark
    Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH, UK
    Curr Biol 18:1802-8. 2008
    ....
  5. ncbi request reprint Regulated membrane recruitment of dynamin-2 mediated by sorting nexin 9
    Richard Lundmark
    Department of Medical Biochemistry and Biophysics, Umea University, S 901 87 Umea, Sweden
    J Biol Chem 279:42694-702. 2004
    ..The results suggest that SNX9-dependent recruitment of Dyn2 to the membrane is regulated by an interaction between SNX9 and aldolase...
  6. pmc The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading
    Gary J Doherty
    MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom
    Mol Biol Cell 22:4380-9. 2011
    ..We propose that GRAF1 remodels membrane microdomains at adhesion sites into endocytic carriers, facilitating membrane turnover during cell morphological changes...
  7. pmc EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization
    Björn Morén
    Medical Biochemistry and Biophysics, Laboratory for Molecular Infection Medicine, Sweden, Umea University, Umea, Sweden
    Mol Biol Cell 23:1316-29. 2012
    ..Thus, following the identification of caveolin and cavins, EHD2 constitutes a third structural component of caveolae involved in controlling the stability and turnover of this organelle...
  8. ncbi request reprint Expression and properties of sorting nexin 9 in dynamin-mediated endocytosis
    Richard Lundmark
    Department of Medical Biochemistry and Biophysics, Umea University, Sweden
    Methods Enzymol 404:545-56. 2005
    ..Assays are presented to investigate the requirements for SNX9-dependent membrane recruitment of dynamin in vitro and in vivo...
  9. doi request reprint SNX9 - a prelude to vesicle release
    Richard Lundmark
    Department of Medical Biochemistry and Biophysics, Umea University, S 90187 Umea, Sweden
    J Cell Sci 122:5-11. 2009
    ..In this Commentary, we summarize several aspects of SNX9 structure and function in the context of membrane remodeling, discuss its interplay with various interaction partners and present a model of how SNX9 might work in endocytosis...
  10. doi request reprint SNX18 is an SNX9 paralog that acts as a membrane tubulator in AP-1-positive endosomal trafficking
    Karin Håberg
    Department of Medical Biochemistry and Biophysics, Umea University, Umea, Sweden
    J Cell Sci 121:1495-505. 2008
    ..The results indicate that SNX9-family members make up discrete membrane-scission units together with dynamin, and suggest that SNX18 mediates budding of carriers for AP-1-positive endosomal trafficking...
  11. ncbi request reprint Sorting nexin 9 participates in clathrin-mediated endocytosis through interactions with the core components
    Richard Lundmark
    Department of Medical Biochemistry and Biophysics, Umea University, S 901 87 Umea, Sweden
    J Biol Chem 278:46772-81. 2003
    ..Overexpression in both K562 and HeLa cells of truncated forms of SNX9 interfered with the uptake of transferrin, consistent with a role of SNX9 in endocytosis...
  12. pmc The beta-appendages of the four adaptor-protein (AP) complexes: structure and binding properties, and identification of sorting nexin 9 as an accessory protein to AP-2
    Richard Lundmark
    Department of Medical Biochemistry and Biophysics, Umea University, S 901 87 Umea, Sweden
    Biochem J 362:597-607. 2002
    ..SNX9, which contains a phox and an Src homology 3 domain, was found in large complexes and was at least partially associated with AP-2 in the cytosol. SNX9 may function to assist AP-2 in its role at the plasma membrane...
  13. pmc The PX-BAR membrane-remodeling unit of sorting nexin 9
    Olena Pylypenko
    Department of Physical Biochemistry, Max Planck Institute for Molecular Physiology, Dortmund, Germany
    EMBO J 26:4788-800. 2007
    ..The study provides insights into the SNX9-induced membrane modulation mechanism...