Research Topics
| M WulltSummaryAffiliation: Lund University Country: Sweden Publications
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Detail Information
Publications
Lactobacillus plantarum 299v for the treatment of recurrent Clostridium difficile-associated diarrhoea: a double-blind, placebo-controlled trialMarlene Wullt
Department of Infectious Diseases, University Hospital Malmo, Malmo, Sweden
Scand J Infect Dis 35:365-7. 2003..plantarum in patients with RCDAD, these results may contribute to the ongoing discussion about the benefits of probiotics in patients with RCDAD and encourage the performance of larger multicentre studies...- Comparison of AP-PCR typing and PCR-ribotyping for estimation of nosocomial transmission of Clostridium difficileM Wullt
Department of Infectious Diseases, University Hospital Malmo, SE 205 02 Malmo, Sweden
J Hosp Infect 55:124-30. 2003..We conclude, that of these two PCR-based options for typing of C. difficile PCR ribotyping offers a superior experimental robustness compared with AP-PCR typing... - A double-blind randomized controlled trial of fusidic acid and metronidazole for treatment of an initial episode of Clostridium difficile-associated diarrhoeaMarlene Wullt
Department of Infectious Diseases, University Hospital, Malmo, Sweden
J Antimicrob Chemother 54:211-6. 2004..Few treatment options are currently available to treat patients suffering from an initial episode of Clostridium difficile-associated diarrhoea (CDAD)... 
Frequent emergence of resistance in Clostridium difficile during treatment of C. difficile-associated diarrhea with fusidic acidT Noren
Department of Infectious Diseases, Orebro University Hospital, S 701 85 Orebro, Sweden
Antimicrob Agents Chemother 50:3028-32. 2006..Development of resistance in C. difficile was frequent in patients given fusidic acid, but it was without apparent negative impact on therapeutic efficacy in the actual CDAD episode...- Mutations in fusA associated with posttherapy fusidic acid resistance in Clostridium difficileT Noren
Department of Infectious Diseases, Orebro University Hospital, SE 701 85 Orebro, Sweden
Antimicrob Agents Chemother 51:1840-3. 2007..Five of these mutations have previously been described in fusA of fusidic acid-resistant Staphylococcus aureus, but seven were novel fusA mutations. Fusidic acid monotherapy for CDAD seemed to rapidly select conserved resistant mutants... - IgG antibody response to toxins A and B in patients with Clostridium difficile infectionM Wullt
Infectious Diseases Research Unit, Department of Clinical Sciences, Lund University, Malmo, Sweden
Clin Vaccine Immunol 19:1552-4. 2012..The results imply that the general serum reactivity against toxins A and B in the population reduces the risk of CDI, which suggests implications for vaccine strategies... 
Lactobacillus plantarum 299v reduces colonisation of Clostridium difficile in critically ill patients treated with antibioticsB Klarin
Department of Anaesthesiology and Intensive Care, University Hospital, Lund, Sweden
Acta Anaesthesiol Scand 52:1096-102. 2008..We investigated intensive care unit (ICU) patients with respect to the impact of Lp299v on C. difficile colonisation and on gut permeability and parameters of inflammation and infection in that context...- A head-to-head comparison of hydrogen peroxide vapor and aerosol room decontamination systemsT Holmdahl
Infectious Diseases Unit, Department of Clinical Sciences, Lund University, Malmo, Sweden
Infect Control Hosp Epidemiol 32:831-6. 2011..There are several hydrogen peroxide-based area decontamination technologies on the market, but no head-to-head studies have been performed... - Pharmacodynamic studies of vancomycin, metronidazole and fusidic acid against Clostridium difficileInga Odenholt
Infectious Diseases Research Unit, Department of Clinical Sciences, Malmo, Sweden
Chemotherapy 53:267-74. 2007..Pharmacodynamic studies of antibiotics have attracted great interest in recent years. However, studies on the pharmacodynamics of different antibiotics against Clostridium difficile are scarce... - Increased sporulation rate of epidemic Clostridium difficile Type 027/NAP1Thomas Akerlund
Swedish Institute for Infectious Disease Control, Department of Bacteriology, SE 171 82, Solna, Sweden
J Clin Microbiol 46:1530-3. 2008..Type 027 produced 3- to 13-fold more toxin than did major Swedish types. One epidemic strain (027/NAP1a) sporulated more than did other type 027 isolates, a feature that should contribute to its survival and spread... - Lactobacillus plantarum 299v enhances the concentrations of fecal short-chain fatty acids in patients with recurrent clostridium difficile-associated diarrheaMarlene Wullt
Infectious Diseases Research Unit, Department of Clinical Sciences, Lund University, 20502 Malmo, Sweden
Dig Dis Sci 52:2082-6. 2007..The intake of this probiotic strain may thereby provide an additional benefit for patients with recurrent Clostridium difficile-associated diarrhea... - Activity of three disinfectants and acidified nitrite against Clostridium difficile sporesMarlene Wullt
Department of Infectious Diseases, Lund University, , Malm, Sweden
Infect Control Hosp Epidemiol 24:765-8. 2003..As acidified nitrite and peracetyl ions are considered to be environmentally safe chemicals, these agents seem well suited for the disinfection of C. difficile spores in the hospital environment...