E Tufvesson

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. doi request reprint Increase of club cell (Clara) protein (CC16) in plasma and urine after exercise challenge in asthmatics and healthy controls, and correlations to exhaled breath temperature and exhaled nitric oxide
    Ellen Tufvesson
    Respiratory Medicine and Allergology, Dept of Clinical Sciences, Lund University, 221 84 Lund, Sweden Electronic address
    Respir Med 107:1675-81. 2013
  2. pmc Splicosomal and serine and arginine-rich splicing factors as targets for TGF-β
    Oskar Hallgren
    Department of Experimental Medical Science, Lund University, Lund, Sweden
    Fibrogenesis Tissue Repair 5:6. 2012
  3. doi request reprint Inflammatory biomarkers in sputum predict COPD exacerbations
    Ellen Tufvesson
    Respiratory Medicine and Allergology, Department of Clinical Sciences, BMC, D12, Lund University, 221 84, Lund, Sweden
    Lung 191:413-6. 2013
  4. doi request reprint Leukotriene receptors are differently expressed in fibroblast from peripheral versus central airways in asthmatics and healthy controls
    Ellen Tufvesson
    Respiratory Medicine and Allergology, Department of Clinical Sciences in Lund, Lund University, Lund, Sweden
    Prostaglandins Leukot Essent Fatty Acids 85:67-73. 2011
  5. doi request reprint Increased cysteinyl-leukotrienes and 8-isoprostane in exhaled breath condensate from systemic sclerosis patients
    Ellen Tufvesson
    Department of Clinical Sciences, Lund, Division of Respiratory Medicine and Allergology, BMC, D12, Lund University, 221 84 Lund, Sweden
    Rheumatology (Oxford) 49:2322-6. 2010
  6. doi request reprint Levels of cysteinyl-leukotrienes in exhaled breath condensate are not due to saliva contamination
    Ellen Tufvesson
    Respiratory Medicine and Allergology, Department of Clinical Sciences in Lund, Lund University, Lund, Sweden
    Clin Respir J 4:83-8. 2010
  7. ncbi request reprint Peripheral nitric oxide is increased in rhinitic patients with asthma compared to bronchial hyperresponsiveness
    Ellen Tufvesson
    Respiratory Medicine and Allergology, Department of Clinical Sciences, Lund University, 221 85 Lund, Sweden
    Respir Med 101:2321-6. 2007
  8. ncbi request reprint Cysteinyl-leukotriene levels in sputum differentiate asthma from rhinitis patients with or without bronchial hyperresponsiveness
    E Tufvesson
    Department of Respiratory Medicine and Allergology, University Hospital, Lund, Sweden
    Clin Exp Allergy 37:1067-73. 2007
  9. ncbi request reprint Methodological improvements for measuring eicosanoids and cytokines in exhaled breath condensate
    Ellen Tufvesson
    Department of Respiratory Medicine and Allergology, University Hospital, 221 85 Lund, Sweden
    Respir Med 100:34-8. 2006
  10. ncbi request reprint Allergic rhinitis with or without concomitant asthma: difference in perception of dyspnoea and levels of fractional exhaled nitric oxide
    D Aronsson
    Institution of Clinical Medicine and Science, Department of Respiratory Medicine and Allergology, Lund, Sweden
    Clin Exp Allergy 35:1457-61. 2005

Collaborators

Detail Information

Publications27

  1. doi request reprint Increase of club cell (Clara) protein (CC16) in plasma and urine after exercise challenge in asthmatics and healthy controls, and correlations to exhaled breath temperature and exhaled nitric oxide
    Ellen Tufvesson
    Respiratory Medicine and Allergology, Dept of Clinical Sciences, Lund University, 221 84 Lund, Sweden Electronic address
    Respir Med 107:1675-81. 2013
    ..CC16 levels in plasma correlated to EBT and exhaled NO, reflecting an overall epithelial involvement. There was no difference between asthmatics and healthy controls, showing a physiological rather than pathophysiological response. ..
  2. pmc Splicosomal and serine and arginine-rich splicing factors as targets for TGF-β
    Oskar Hallgren
    Department of Experimental Medical Science, Lund University, Lund, Sweden
    Fibrogenesis Tissue Repair 5:6. 2012
    ..abstract:..
  3. doi request reprint Inflammatory biomarkers in sputum predict COPD exacerbations
    Ellen Tufvesson
    Respiratory Medicine and Allergology, Department of Clinical Sciences, BMC, D12, Lund University, 221 84, Lund, Sweden
    Lung 191:413-6. 2013
    ..It is desirable to predict an oncoming exacerbation before it occurs. The aim of the present study was to identify biomarkers that may predict a forthcoming exacerbation...
  4. doi request reprint Leukotriene receptors are differently expressed in fibroblast from peripheral versus central airways in asthmatics and healthy controls
    Ellen Tufvesson
    Respiratory Medicine and Allergology, Department of Clinical Sciences in Lund, Lund University, Lund, Sweden
    Prostaglandins Leukot Essent Fatty Acids 85:67-73. 2011
    ..Leukotriene receptors are differently expressed in fibroblasts from peripheral compared to central airways, which may explain a suggested cysteinyl-leukotriene driven remodeling mainly in the peripheral airways...
  5. doi request reprint Increased cysteinyl-leukotrienes and 8-isoprostane in exhaled breath condensate from systemic sclerosis patients
    Ellen Tufvesson
    Department of Clinical Sciences, Lund, Division of Respiratory Medicine and Allergology, BMC, D12, Lund University, 221 84 Lund, Sweden
    Rheumatology (Oxford) 49:2322-6. 2010
    ..The aim of this study was to investigate the amount of LTs and 8-isoprostane, a marker of oxidative stress, in exhaled breath condensate (EBC) from SSc patients...
  6. doi request reprint Levels of cysteinyl-leukotrienes in exhaled breath condensate are not due to saliva contamination
    Ellen Tufvesson
    Respiratory Medicine and Allergology, Department of Clinical Sciences in Lund, Lund University, Lund, Sweden
    Clin Respir J 4:83-8. 2010
    ..We thereby aimed to find out whether saliva contamination could be a plausible explanation to the levels found in EBC or not...
  7. ncbi request reprint Peripheral nitric oxide is increased in rhinitic patients with asthma compared to bronchial hyperresponsiveness
    Ellen Tufvesson
    Respiratory Medicine and Allergology, Department of Clinical Sciences, Lund University, 221 85 Lund, Sweden
    Respir Med 101:2321-6. 2007
    ..The results support our hypothesis that rhinitic patients with asthma have more peripheral lung inflammation and small airway involvement compared to rhinitic patients with BHR alone...
  8. ncbi request reprint Cysteinyl-leukotriene levels in sputum differentiate asthma from rhinitis patients with or without bronchial hyperresponsiveness
    E Tufvesson
    Department of Respiratory Medicine and Allergology, University Hospital, Lund, Sweden
    Clin Exp Allergy 37:1067-73. 2007
    ..We have previously reported that asthma differs from rhinitis with or without bronchial hyperresponsiveness in the perception and degree of lower airway inflammation...
  9. ncbi request reprint Methodological improvements for measuring eicosanoids and cytokines in exhaled breath condensate
    Ellen Tufvesson
    Department of Respiratory Medicine and Allergology, University Hospital, 221 85 Lund, Sweden
    Respir Med 100:34-8. 2006
    ..Because of low concentrations of inflammatory markers, potential loss in the sampling system may have great influence. The aim of the present study was to se if evaporation and plastic coating could facilitate detection...
  10. ncbi request reprint Allergic rhinitis with or without concomitant asthma: difference in perception of dyspnoea and levels of fractional exhaled nitric oxide
    D Aronsson
    Institution of Clinical Medicine and Science, Department of Respiratory Medicine and Allergology, Lund, Sweden
    Clin Exp Allergy 35:1457-61. 2005
    ..The aim of the present study was to investigate whether patients with AR and asthma differed from AR with or without BHR in degree of perception of dyspnoea and airway inflammation, measured as fractionated exhaled nitric oxide (NO)...
  11. ncbi request reprint Increased alveolar nitric oxide in early systemic sclerosis
    D M Wuttge
    Department of Clinical Sciences, Lund, Sweden
    Clin Exp Rheumatol 28:S5-9. 2010
    ..Nitric oxide (NO) has gained attention in the pathogenesis of SSc. The aim of the study was to investigate alveolar NO concentration (CA(NO)) in SSc patients with short disease duration and to relate CA(NO) to radiologic findings...
  12. doi request reprint Alveolar mast cells shift to an FcεRI-expressing phenotype in mild atopic asthma: a novel feature in allergic asthma pathology
    C K Andersson
    Department of Respiratory Medicine and Allergology, Lund University, Lund, Sweden
    Allergy 66:1590-7. 2011
    ..This study investigates whether increased FcεRI-expressing alveolar mast cells are present in patients with mild allergic asthma or even in non-asthmatic allergic rhinitis patients (AR) who have developed bronchial hyperactivity (BHR)...
  13. ncbi request reprint BALF-derived fibroblasts differ from biopsy-derived fibroblasts in systemic sclerosis
    A Scheja
    Dept of Rheumatology, Lund University Hospital, S 221 85 Lund, Sweden
    Eur Respir J 29:446-52. 2007
    ..These findings indicate a possible role for eosinophil-fibroblast interaction in pulmonary fibrosis in systemic sclerosis...
  14. ncbi request reprint Allergic rhinitis with hyper-responsiveness differ from asthma in degree of peripheral obstruction during metacholine challenge test
    David Aronsson
    Department of Respiratory Medicine and Allergology, Institution of Clinical Medicine and Science, University Hospital, Lund, Sweden
    Clin Physiol Funct Imaging 28:81-5. 2008
    ..Increased peripheral obstruction in the asthmatic group compared to patients with AR and BHR may explain previous findings that asthmatics perceive greater airway obstruction during MCh challenge tests...
  15. doi request reprint Altered matrix production in the distal airways of individuals with asthma
    Kristian Nihlberg
    Experimental Medical Science, Klinikgatan 32, Lund, Sweden
    Thorax 65:670-6. 2010
    ..The aim of this study was to compare control subjects and those with mild asthma in relation to fibroblast phenotypes and remodelling in central and distal airways...
  16. doi request reprint Comparison of central and peripheral airway involvement before and during methacholine, mannitol and eucapnic hyperventilation challenges in mild asthmatics
    David Aronsson
    Department of Respiratory Medicine and Allergology, Institution of Clinical Medicine and Science, Lund, Sweden
    Clin Respir J 5:10-8. 2011
    ....
  17. ncbi request reprint Alteration of proteoglycan synthesis in human lung fibroblasts induced by interleukin-1beta and tumor necrosis factor-alpha
    E Tufvesson
    Department of Cell and Molecular Biology, Lund University, S 221 00 Lund, Sweden
    J Cell Biochem 77:298-309. 2000
    ..In summary, our study indicates that these proinflammatory cytokines affect the regulation of extracellular matrix production, which is of importance for the inflammatory process...
  18. doi request reprint Increased serum type I interferon activity in early systemic sclerosis patients is associated with antibodies against Sjögren's syndrome antigens and nuclear ribonucleoprotein antigens
    D M Wuttge
    Section of Rheumatology, Department of Clinical Sciences, Lund University Skåne University Hospital, Lund, Sweden
    Scand J Rheumatol 42:235-40. 2013
    ..To study serum type I interferon (IFN) activity in patients with early systemic sclerosis (SSc)...
  19. ncbi request reprint Presence of activated mobile fibroblasts in bronchoalveolar lavage from patients with mild asthma
    Kristoffer Larsen
    Department of Cell and Molecular Biology, Lund University, Lund, Sweden
    Am J Respir Crit Care Med 170:1049-56. 2004
    ....
  20. doi request reprint Asthma is more prevalent in elite swimming adolescents despite better mental and physical health
    K Romberg
    Department of Respiratory Medicine and Allergology, Lund University, Lund, Sweden
    Scand J Med Sci Sports 22:362-71. 2012
    ..Despite an increased prevalence of asthma symptoms, the swimmers reported best physical performance and best mental and physical well-being. They also had a healthier lifestyle without smoking and low alcohol consumption...
  21. ncbi request reprint Biglycan and decorin induce morphological and cytoskeletal changes involving signalling by the small GTPases RhoA and Rac1 resulting in lung fibroblast migration
    Ellen Tufvesson
    Section for Cell and Matrix Biology, Department of Cell and Molecular Biology, BMC C13, Lund University, 221 84 Lund, Sweden
    J Cell Sci 116:4857-64. 2003
    ..In summary, these data indicate that biglycan- and decorin-induced fibroblast cytoskeletal and signalling changes result in an increased cell migration, and demonstrate their potential role in the remodelling process...
  22. ncbi request reprint Activation of platelet-derived growth factor pathway in human asthmatic pulmonary-derived mesenchymal cells
    Johan Malmstrom
    Department of Cell and Molecular Biology, BMCC13, Lund University, Sweden
    Electrophoresis 24:276-85. 2003
    ..We demonstrate that PDGF has a potential pathological role in asthma and formation of subepithelial fibrosis by inducing changes in the proteome...
  23. ncbi request reprint Proteome annotations and identifications of the human pulmonary fibroblast
    Johan Malmstrom
    Cell and Molecular Biology, C13, BMC, 221 84 Lund, Sweden
    J Proteome Res 3:525-37. 2004
    ..The use of functional assays that demonstrate the key regulating role of growth factors and cytokine stimuli such as PDGF, TGF-beta, and EGF and the effect of ECM molecules such as Biglycan, are also presented and discussed...
  24. ncbi request reprint Nanocapillary liquid chromatography interfaced to tandem matrix-assisted laser desorption/ionization and electrospray ionization-mass spectrometry: mapping the nuclear proteome of human fibroblasts
    Johan Malmstrom
    Cell and Molecular Biology, BMC, C13, University of Lund, Lund, Sweden
    Electrophoresis 24:3806-14. 2003
    ..These findings are of particular importance due to the disease link of these targets cells...
  25. ncbi request reprint Biglycan isoforms with differences in polysaccharide substitution and core protein in human lung fibroblasts
    Ellen Tufvesson
    Department of Cell and Molecular Biology, BMC, Lund University, Sweden
    Eur J Biochem 269:3688-96. 2002
    ..We can anticipate that variation in structure of biglycan can cause changes in the connective tissue formation depending on its ability to bind matrix molecules, as well as cytokines...
  26. ncbi request reprint Tumour necrosis factor-alpha interacts with biglycan and decorin
    Ellen Tufvesson
    Section for Cell and Matrix Biology, Department of Cell and Molecular Biology, BMC C13, Lund University, Sweden
    FEBS Lett 530:124-8. 2002
    ..53 microM. The function of this interaction between TNF-alpha and biglycan and decorin is not known, but we suggest that the differential localisation of the proteoglycans enables the cytokines to be immobilised in different environments...
  27. ncbi request reprint The importance of fibroblasts in remodelling of the human uterine cervix during pregnancy and parturition
    Erik Malmström
    Department of Experimental Medical Science, BMC, Lund University, Lund, Sweden
    Mol Hum Reprod 13:333-41. 2007
    ..Our data suggest that remodelling of the human cervix is orchestrated by fibroblasts, which are activated or recruited by the inflammatory processes occurring during the ripening cascade...