Research Topics
Species | E TufvessonSummaryAffiliation: Lund University Country: Sweden Publications
| Collaborators
|
Detail Information
Publications
Peripheral nitric oxide is increased in rhinitic patients with asthma compared to bronchial hyperresponsivenessEllen Tufvesson
Respiratory Medicine and Allergology, Department of Clinical Sciences, Lund University, 221 85 Lund, Sweden
Respir Med 101:2321-6. 2007..The results support our hypothesis that rhinitic patients with asthma have more peripheral lung inflammation and small airway involvement compared to rhinitic patients with BHR alone...
Leukotriene receptors are differently expressed in fibroblast from peripheral versus central airways in asthmatics and healthy controlsEllen Tufvesson
Respiratory Medicine and Allergology, Department of Clinical Sciences in Lund, Lund University, Lund, Sweden
Prostaglandins Leukot Essent Fatty Acids 85:67-73. 2011..Leukotriene receptors are differently expressed in fibroblasts from peripheral compared to central airways, which may explain a suggested cysteinyl-leukotriene driven remodeling mainly in the peripheral airways...- Cysteinyl-leukotriene levels in sputum differentiate asthma from rhinitis patients with or without bronchial hyperresponsivenessE Tufvesson
Department of Respiratory Medicine and Allergology, University Hospital, Lund, Sweden
Clin Exp Allergy 37:1067-73. 2007..We have previously reported that asthma differs from rhinitis with or without bronchial hyperresponsiveness in the perception and degree of lower airway inflammation... - Increased cysteinyl-leukotrienes and 8-isoprostane in exhaled breath condensate from systemic sclerosis patientsEllen Tufvesson
Department of Clinical Sciences, Lund, Division of Respiratory Medicine and Allergology, BMC, D12, Lund University, 221 84 Lund, Sweden
Rheumatology (Oxford) 49:2322-6. 2010..The aim of this study was to investigate the amount of LTs and 8-isoprostane, a marker of oxidative stress, in exhaled breath condensate (EBC) from SSc patients... - Levels of cysteinyl-leukotrienes in exhaled breath condensate are not due to saliva contaminationEllen Tufvesson
Respiratory Medicine and Allergology, Department of Clinical Sciences in Lund, Lund University, Lund, Sweden
Clin Respir J 4:83-8. 2010..We thereby aimed to find out whether saliva contamination could be a plausible explanation to the levels found in EBC or not... - Methodological improvements for measuring eicosanoids and cytokines in exhaled breath condensateEllen Tufvesson
Department of Respiratory Medicine and Allergology, University Hospital, 221 85 Lund, Sweden
Respir Med 100:34-8. 2006..Because of low concentrations of inflammatory markers, potential loss in the sampling system may have great influence. The aim of the present study was to se if evaporation and plastic coating could facilitate detection... - Allergic rhinitis with or without concomitant asthma: difference in perception of dyspnoea and levels of fractional exhaled nitric oxideD Aronsson
Institution of Clinical Medicine and Science, Department of Respiratory Medicine and Allergology, Lund, Sweden
Clin Exp Allergy 35:1457-61. 2005..However, FENO measurement indicates that dyspnoea may also be associated with increased inflammatory activity in the peripheral airways... - Increased alveolar nitric oxide in early systemic sclerosisD M Wuttge
Department of Clinical Sciences, Lund, Sweden
Clin Exp Rheumatol 28:S5-9. 2010..Nitric oxide (NO) has gained attention in the pathogenesis of SSc. The aim of the study was to investigate alveolar NO concentration (CA(NO)) in SSc patients with short disease duration and to relate CA(NO) to radiologic findings... - Alveolar mast cells shift to an FcεRI-expressing phenotype in mild atopic asthma: a novel feature in allergic asthma pathologyC K Andersson
Department of Respiratory Medicine and Allergology, Lund University, Lund, Sweden
Allergy 66:1590-7. 2011..This study investigates whether increased FcεRI-expressing alveolar mast cells are present in patients with mild allergic asthma or even in non-asthmatic allergic rhinitis patients (AR) who have developed bronchial hyperactivity (BHR)... - BALF-derived fibroblasts differ from biopsy-derived fibroblasts in systemic sclerosisA Scheja
Dept of Rheumatology, Lund University Hospital, S 221 85 Lund, Sweden
Eur Respir J 29:446-52. 2007..These findings indicate a possible role for eosinophil-fibroblast interaction in pulmonary fibrosis in systemic sclerosis... - Altered matrix production in the distal airways of individuals with asthmaKristian Nihlberg
Experimental Medical Science, Klinikgatan 32, Lund, Sweden
Thorax 65:670-6. 2010..The aim of this study was to compare control subjects and those with mild asthma in relation to fibroblast phenotypes and remodelling in central and distal airways... - Allergic rhinitis with hyper-responsiveness differ from asthma in degree of peripheral obstruction during metacholine challenge testDavid Aronsson
Department of Respiratory Medicine and Allergology, Institution of Clinical Medicine and Science, University Hospital, Lund, Sweden
Clin Physiol Funct Imaging 28:81-5. 2008..Increased peripheral obstruction in the asthmatic group compared to patients with AR and BHR may explain previous findings that asthmatics perceive greater airway obstruction during MCh challenge tests... - Comparison of central and peripheral airway involvement before and during methacholine, mannitol and eucapnic hyperventilation challenges in mild asthmaticsDavid Aronsson
Department of Respiratory Medicine and Allergology, Institution of Clinical Medicine and Science, Lund, Sweden
Clin Respir J 5:10-8. 2011.... - Presence of activated mobile fibroblasts in bronchoalveolar lavage from patients with mild asthmaKristoffer Larsen
Department of Cell and Molecular Biology, Lund University, Lund, Sweden
Am J Respir Crit Care Med 170:1049-56. 2004.... - Alteration of proteoglycan synthesis in human lung fibroblasts induced by interleukin-1beta and tumor necrosis factor-alphaE Tufvesson
Department of Cell and Molecular Biology, Lund University, S 221 00 Lund, Sweden
J Cell Biochem 77:298-309. 2000..In summary, our study indicates that these proinflammatory cytokines affect the regulation of extracellular matrix production, which is of importance for the inflammatory process... - Biglycan and decorin induce morphological and cytoskeletal changes involving signalling by the small GTPases RhoA and Rac1 resulting in lung fibroblast migrationEllen Tufvesson
Section for Cell and Matrix Biology, Department of Cell and Molecular Biology, BMC C13, Lund University, 221 84 Lund, Sweden
J Cell Sci 116:4857-64. 2003..In summary, these data indicate that biglycan- and decorin-induced fibroblast cytoskeletal and signalling changes result in an increased cell migration, and demonstrate their potential role in the remodelling process... - Asthma is more prevalent in elite swimming adolescents despite better mental and physical healthK Romberg
Department of Respiratory Medicine and Allergology, Lund University, Lund, Sweden
Scand J Med Sci Sports 22:362-71. 2012..Despite an increased prevalence of asthma symptoms, the swimmers reported best physical performance and best mental and physical well-being. They also had a healthier lifestyle without smoking and low alcohol consumption... - Proteome annotations and identifications of the human pulmonary fibroblastJohan Malmstrom
Cell and Molecular Biology, C13, BMC, 221 84 Lund, Sweden
J Proteome Res 3:525-37. 2004..The use of functional assays that demonstrate the key regulating role of growth factors and cytokine stimuli such as PDGF, TGF-beta, and EGF and the effect of ECM molecules such as Biglycan, are also presented and discussed... - Nanocapillary liquid chromatography interfaced to tandem matrix-assisted laser desorption/ionization and electrospray ionization-mass spectrometry: mapping the nuclear proteome of human fibroblastsJohan Malmstrom
Cell and Molecular Biology, BMC, C13, University of Lund, Lund, Sweden
Electrophoresis 24:3806-14. 2003..These findings are of particular importance due to the disease link of these targets cells... - Activation of platelet-derived growth factor pathway in human asthmatic pulmonary-derived mesenchymal cellsJohan Malmstrom
Department of Cell and Molecular Biology, BMCC13, Lund University, Sweden
Electrophoresis 24:276-85. 2003..We demonstrate that PDGF has a potential pathological role in asthma and formation of subepithelial fibrosis by inducing changes in the proteome... - Biglycan isoforms with differences in polysaccharide substitution and core protein in human lung fibroblastsEllen Tufvesson
Department of Cell and Molecular Biology, BMC, Lund University, Sweden
Eur J Biochem 269:3688-96. 2002..We can anticipate that variation in structure of biglycan can cause changes in the connective tissue formation depending on its ability to bind matrix molecules, as well as cytokines... - Tumour necrosis factor-alpha interacts with biglycan and decorinEllen Tufvesson
Section for Cell and Matrix Biology, Department of Cell and Molecular Biology, BMC C13, Lund University, Sweden
FEBS Lett 530:124-8. 2002..53 microM. The function of this interaction between TNF-alpha and biglycan and decorin is not known, but we suggest that the differential localisation of the proteoglycans enables the cytokines to be immobilised in different environments... - The importance of fibroblasts in remodelling of the human uterine cervix during pregnancy and parturitionErik Malmström
Department of Experimental Medical Science, BMC, Lund University, Lund, Sweden
Mol Hum Reprod 13:333-41. 2007..Our data suggest that remodelling of the human cervix is orchestrated by fibroblasts, which are activated or recruited by the inflammatory processes occurring during the ripening cascade...