Catharina Svanborg

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. pmc A genetic basis of susceptibility to acute pyelonephritis
    Ann Charlotte Lundstedt
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    PLoS ONE 2:e825. 2007
  2. pmc Acute pyelonephritis and renal scarring are caused by dysfunctional innate immunity in mCxcr2 heterozygous mice
    Majlis Svensson
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    Kidney Int 80:1064-72. 2011
  3. pmc Pathogen specific, IRF3-dependent signaling and innate resistance to human kidney infection
    Hans Fischer
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    PLoS Pathog 6:e1001109. 2010
  4. pmc Genetic control of the variable innate immune response to asymptomatic bacteriuria
    Jenny Grönberg-Hernandez
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    PLoS ONE 6:e28289. 2011
  5. pmc Prevention and treatment of colon cancer by peroral administration of HAMLET (human α-lactalbumin made lethal to tumour cells)
    Manoj Puthia
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    Gut 63:131-42. 2014
  6. pmc A unifying mechanism for cancer cell death through ion channel activation by HAMLET
    Petter Storm
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    PLoS ONE 8:e58578. 2013
  7. pmc HAMLET binding to α-actinin facilitates tumor cell detachment
    Maria Trulsson
    Institute of Laboratory Medicine, Department of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden
    PLoS ONE 6:e17179. 2011
  8. pmc Low resolution solution structure of HAMLET and the importance of its alpha-domains in tumoricidal activity
    C S James Ho
    Department of Microbiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    PLoS ONE 7:e53051. 2012
  9. ncbi request reprint Urinary tract infections in children: microbial virulence versus host susceptibility
    Catharina Svanborg
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    Adv Exp Med Biol 764:205-10. 2013
  10. ncbi request reprint Uropathogenic Escherichia coli as a model of host-parasite interaction
    Catharina Svanborg
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    Curr Opin Microbiol 9:33-9. 2006

Collaborators

Detail Information

Publications54

  1. pmc A genetic basis of susceptibility to acute pyelonephritis
    Ann Charlotte Lundstedt
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    PLoS ONE 2:e825. 2007
    ..The IL-8 receptor, CXCR1, was identified as a candidate gene when mIL-8Rh mutant mice developed acute pyelonephritis (APN) with severe tissue damage...
  2. pmc Acute pyelonephritis and renal scarring are caused by dysfunctional innate immunity in mCxcr2 heterozygous mice
    Majlis Svensson
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    Kidney Int 80:1064-72. 2011
    ..Hence, the known heterozygous CXCR1 polymorphisms may predispose patients to acute pyelonephritis and urosepsis...
  3. pmc Pathogen specific, IRF3-dependent signaling and innate resistance to human kidney infection
    Hans Fischer
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    PLoS Pathog 6:e1001109. 2010
    ..Host susceptibility to common infections like UTI may thus be strongly influenced by single gene modifications affecting the innate immune response...
  4. pmc Genetic control of the variable innate immune response to asymptomatic bacteriuria
    Jenny Grönberg-Hernandez
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    PLoS ONE 6:e28289. 2011
    ..The results suggest that the host-specific, low immune response to ABU mainly includes innate immune mediators and that host genetics directly influence the magnitude of this response...
  5. pmc Prevention and treatment of colon cancer by peroral administration of HAMLET (human α-lactalbumin made lethal to tumour cells)
    Manoj Puthia
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    Gut 63:131-42. 2014
    ..Examining whether HAMLET (human α-lactalbumin made lethal to tumour cells) may be used for colon cancer treatment is logical, based on the properties of the complex and its biological context...
  6. pmc A unifying mechanism for cancer cell death through ion channel activation by HAMLET
    Petter Storm
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    PLoS ONE 8:e58578. 2013
    ..The results also suggest that HAMLET offers a two-tiered therapeutic approach, killing cancer cells while stimulating an innate immune response in surrounding healthy tissues...
  7. pmc HAMLET binding to α-actinin facilitates tumor cell detachment
    Maria Trulsson
    Institute of Laboratory Medicine, Department of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden
    PLoS ONE 6:e17179. 2011
    ..As α-actinins also associate with signaling molecules, cytoplasmic domains of transmembrane receptors and ion channels, additional α-actinin-dependent mechanisms are discussed...
  8. pmc Low resolution solution structure of HAMLET and the importance of its alpha-domains in tumoricidal activity
    C S James Ho
    Department of Microbiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    PLoS ONE 7:e53051. 2012
    ..In addition, shorter peptides corresponding to those domains are biologically active. These findings provide novel insights into the structural prerequisites for the dramatic effects of HAMLET on tumor cells...
  9. ncbi request reprint Urinary tract infections in children: microbial virulence versus host susceptibility
    Catharina Svanborg
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    Adv Exp Med Biol 764:205-10. 2013
    ..Finally, we propose that the prediction of future disease risk and decisions on prophylaxis and invasive diagnostic procedures might be improved by genetic analysis...
  10. ncbi request reprint Uropathogenic Escherichia coli as a model of host-parasite interaction
    Catharina Svanborg
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    Curr Opin Microbiol 9:33-9. 2006
    ..CXCR1 mutant mice become bacteremic and develop renal scars and studies in UTI prone children have detected low CXCR1 expression, suggesting that CXCR1 is also essential for human disease susceptibility...
  11. pmc Inhibition of TIR domain signaling by TcpC: MyD88-dependent and independent effects on Escherichia coli virulence
    Manisha Yadav
    Department of Microbiology, Institute of Laboratory Medicine, Lund University, Sweden
    PLoS Pathog 6:e1001120. 2010
    ..Dysregulation of the host response by microbial TcpC thus appears to impair the protective effects of innate immunity, while promoting inflammation and tissue damage...
  12. pmc Bacterial control of host gene expression through RNA polymerase II
    Nataliya Lutay
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    J Clin Invest 123:2366-79. 2013
    ..Such bacterial modulation of host gene expression may be essential to sustain asymptomatic bacterial carriage by ensuring that potentially destructive immune activation will not occur...
  13. pmc Toll-like receptor 4 promoter polymorphisms: common TLR4 variants may protect against severe urinary tract infection
    Bryndis Ragnarsdottir
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine Lund, Lund University, Lund, Sweden
    PLoS ONE 5:e10734. 2010
    ..Here, we assess variation in TLR4 expression, rather than structure, as a mechanism to diversify innate immune responses...
  14. doi request reprint alpha-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding
    Jenny Pettersson-Kastberg
    Department of Microbiology, Immunology and Glycobiology MIG, Institute of Laboratory Medicine, Faculty of Medicine, Lund University, 223 62 Lund, Sweden
    J Mol Biol 394:994-1010. 2009
    ..We posit that partial unfolding offers another significant route of functional diversification for proteins within the cell...
  15. ncbi request reprint Ceramide as a TLR4 agonist; a putative signalling intermediate between sphingolipid receptors for microbial ligands and TLR4
    Hans Fischer
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Solvegatan 23, S 22362 Lund, Sweden
    Cell Microbiol 9:1239-51. 2007
    ..The results show that ceramide activates TLR4 signalling and suggest that this mechanism might allow pathogens to elicit mucosal TLR4 responses by perturbing sphingolipid receptors for virulence ligands like P fimbriae...
  16. pmc Alpha-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells)
    Malin Svensson
    Department of Microbiology, Immunology and Glycobiology MIG, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    Protein Sci 12:2794-804. 2003
    ..This suggests that the lipid cofactor stabilizes the altered fold without interfering with the Ca(2+)site...
  17. doi request reprint Can misfolded proteins be beneficial? The HAMLET case
    Jenny Pettersson-Kastberg
    Department of Microbiology, Immunology and Glycobiology MIG, Institute of Laboratory Medicine, Lund University, Solvegatan 23, Lund, Sweden
    Ann Med 41:162-76. 2009
    ....
  18. ncbi request reprint Do type 1 fimbriae promote inflammation in the human urinary tract?
    Goran Bergsten
    Department of Microbiology, Immunology, and Glycobiology, Lund University, Lund, Sweden
    Cell Microbiol 9:1766-81. 2007
    ..coli 83972 enhances adherence and inflammation in challenged patients. We conclude that type 1 fimbriae do not contribute to the mucosal inflammatory response in the human urinary tract...
  19. ncbi request reprint Histone deacetylase inhibitors promote the tumoricidal effect of HAMLET
    Patrick Brest
    Institute of Laboratory Medicine, Section of Microbiology, Immunology, and Glycobiology, Lund University, Lund, Sweden
    Cancer Res 67:11327-34. 2007
    ..The results suggest that the synergy of HDIs and HAMLET is based on different but converging death pathways, both involving chromatin alterations. We speculate that HAMLET and HDIs might be combined to promote tumor cell death in vivo...
  20. ncbi request reprint Natural history of renal scarring in susceptible mIL-8Rh-/- mice
    Majlis Svensson
    Institute of Laboratory Medicine, Department of Microbiology, Immunology and Glycobiology, University of Lund, Lund, Sweden
    Kidney Int 67:103-10. 2005
    ..Recently, the interleukin (IL)-8 receptor was shown to control disease susceptibility in mice and low IL-8 receptor expression was observed in pyelonephritis-prone patients...
  21. ncbi request reprint PapG-dependent adherence breaks mucosal inertia and triggers the innate host response
    Goran Bergsten
    Department of Microbiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    J Infect Dis 189:1734-42. 2004
    ..We conclude that PapG-mediated adherence breaks mucosal inertia in the human urinary tract by triggering innate immunity and propose that this activation step differentiates asymptomatic carriage from infection...
  22. pmc Changes in proteasome structure and function caused by HAMLET in tumor cells
    Lotta Gustafsson
    Department of Microbiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    PLoS ONE 4:e5229. 2009
    ..This study examined the proteasome response to HAMLET, a partially unfolded protein-lipid complex, which is internalized by tumor cells and triggers cell death...
  23. doi request reprint Rare emergence of symptoms during long-term asymptomatic Escherichia coli 83972 carriage without an altered virulence factor repertoire
    Bela Köves
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    J Urol 191:519-28. 2014
    ..coli 83972. We examined whether virulence reacquisition by symptom isolates may account for the switch from asymptomatic bacteriuria to symptomatic urinary tract infection...
  24. ncbi request reprint HAMLET kills tumor cells by apoptosis: structure, cellular mechanisms, and therapy
    Lotta Gustafsson
    Institute of Laboratory Medicine, Department of Microbiology, Immunology and Glycobiology, Lund University, Sweden
    J Nutr 135:1299-303. 2005
    ..HAMLET thus shows great promise as a new therapeutic with the advantage of selectivity for tumor cells and lack of toxicity...
  25. doi request reprint Apoptosis and tumor cell death in response to HAMLET (human alpha-lactalbumin made lethal to tumor cells)
    Oskar Hallgren
    Department for Experimental Medical Sciences, Section for Lungbiology, Lund, Sweden
    Adv Exp Med Biol 606:217-40. 2008
    ..This complexity might underlie the rapid death response of tumor cells and the broad antitumor activity of HAMLET...
  26. doi request reprint HAMLET: functional properties and therapeutic potential
    James Ho C S
    Department of Microbiology, Immunology and Glycobiology MIG, Institute of Laboratory Medicine, Lund University, Solvegatan 23, S 223 62 Lund, Sweden
    Future Oncol 8:1301-13. 2012
    ..These findings open up new avenues for cancer therapy and the understanding of conserved death responses in tumor cells...
  27. pmc Lipids as tumoricidal components of human α-lactalbumin made lethal to tumor cells (HAMLET): unique and shared effects on signaling and death
    James C S Ho
    Department of Microbiology, Immunology, and Glycobiology MIG, Institute of Laboratory Medicine, Lund University, Solvegatan 23, S 223 62 Lund, Sweden
    J Biol Chem 288:17460-71. 2013
    ..Fatty acids may thus exert some of their essential effects on host cells when in the deprotonated state and when presented in the context of a partially unfolded protein...
  28. pmc Lipids as cofactors in protein folding: stereo-specific lipid-protein interactions are required to form HAMLET (human alpha-lactalbumin made lethal to tumor cells)
    Malin Svensson
    Department of Microbiology, Immunology and Glycobiology MIG, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    Protein Sci 12:2805-14. 2003
    ..The results offer a new mechanism for the functional diversity of proteins, by exploiting lipids as essential, tissue-specific cofactors in this process...
  29. ncbi request reprint Inherited susceptibility to acute pyelonephritis: a family study of urinary tract infection
    Ann Charlotte Lundstedt
    Department of Microbiology, Immunology, and Glycobiology, Lund University, Lund, S 223 62, Sweden
    J Infect Dis 195:1227-34. 2007
    ..CXCR1 expression was investigated as a factor predisposing to APN, because low CXCR1 expression has been associated with disease susceptibility in mice and disease-prone children...
  30. doi request reprint HAMLET (human alpha-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death
    Sonja Aits
    Institute of Laboratory Medicine, Section of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden
    Int J Cancer 124:1008-19. 2009
    ..The results show that HAMLET triggers macroautophagy in tumor cells and suggest that macroautophagy contributes to HAMLET-induced tumor cell death...
  31. ncbi request reprint Expression of nitric oxide synthase isoforms in the mouse kidney: cellular localization and influence by lipopolysaccharide and Toll-like receptor 4
    Bo Holmqvist
    Department of Pathology, Inst Medical Sciences, Lund University, Lund, Sweden
    J Mol Histol 36:499-516. 2005
    ..These regulatory mechanisms are likely to participate in different pathophysiological conditions affecting NO-mediated renal functions...
  32. ncbi request reprint Compact oleic acid in HAMLET
    Jonas Fast
    Department of Biophysical Chemistry, Lund University, P O Box 124, SE 221 00 Lund, Sweden
    FEBS Lett 579:6095-100. 2005
    ..The data further show that HAMLET is a partly unfolded/molten globule-like complex under physiological conditions...
  33. ncbi request reprint Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival
    Walter Fischer
    Institute of Laboratory Medicine, Department of Microbiology, Immunology and Glycobiology, University of Lund, Solvegatan 23, 223 62 Lund, Sweden
    Cancer Res 64:2105-12. 2004
    ..The results identify HAMLET as a new candidate in cancer therapy and suggest that HAMLET should be additionally explored as a novel approach to controlling GBM progression...
  34. doi request reprint Susceptibility to acute pyelonephritis or asymptomatic bacteriuria: host-pathogen interaction in urinary tract infections
    Bryndis Ragnarsdottir
    Institute of Laboratory Medicine, Section of Microbiology, Immunology and Glycobiology MIG, Lund University, Solvegatan 23, 22362 Lund, Sweden
    Pediatr Nephrol 27:2017-29. 2012
    ..It should be plausible to "individualize" diagnosis and therapy by combining information on bacterial virulence and the host response...
  35. doi request reprint Structure and function of human α-lactalbumin made lethal to tumor cells (HAMLET)-type complexes
    Ann Kristin Mossberg
    Department of Microbiology, Immunology and Glycobiology MIG, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    FEBS J 277:4614-25. 2010
    ....
  36. pmc Toll-like receptor 4 expression and cytokine responses in the human urinary tract mucosa
    Patrik Samuelsson
    Department of Laboratory Medicine, Division of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden
    Infect Immun 72:3179-86. 2004
    ..We speculate that the lack of membrane-bound CD14 allows the epithelium to regulate its sensitivity to lipopolysaccharide and to discriminate between more-virulent and less-virulent strains...
  37. ncbi request reprint HAMLET interacts with histones and chromatin in tumor cell nuclei
    Caroline Duringer
    Institute of Laboratory Medicine, Section for Microbiology, Immunology and Glycobiology, Lund University, Solvegatan 23, 223 62 Lund, Sweden
    J Biol Chem 278:42131-5. 2003
    ..We conclude that HAMLET interacts with histones and chromatin in tumor cell nuclei and propose that this interaction locks the cells into the death pathway by irreversibly disrupting chromatin organization...
  38. ncbi request reprint Escherichia coli, fimbriae, bacterial persistence and host response induction in the human urinary tract
    Goran Bergsten
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    Int J Med Microbiol 295:487-502. 2005
    ..Type 1 fimbriae, in contrast, did not act as virulence factors in this model, and thus appear to serve a different function in man than in the murine model...
  39. ncbi request reprint Reduced toll-like receptor 4 expression in children with asymptomatic bacteriuria
    Bryndis Ragnarsdottir
    Department of Microbiology, Immunology, and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, 22362, Sweden
    J Infect Dis 196:475-84. 2007
    ..Altered TLR4 and adaptor protein expression might impair TLR4 signaling and explain the weak mucosal response to urinary tract infection in patients who develop ABU rather than symptomatic disease...
  40. ncbi request reprint HAMLET kills tumor cells by an apoptosis-like mechanism--cellular, molecular, and therapeutic aspects
    Catharina Svanborg
    Institute of Laboratory Medicine, Department of Microbiology, Immunology and Glycobiology, Lund University, 221 00 Lund, Sweden
    Adv Cancer Res 88:1-29. 2003
    ..This mechanism may contribute to the protective effect of breastfeeding against childhood tumors. We propose that HAMLET should be explored as a novel approach to tumor therapy...
  41. ncbi request reprint Glycolipid receptor depletion as an approach to specific antimicrobial therapy
    Majlis Svensson
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, University of Lund, Lund, Sweden
    FEMS Microbiol Lett 258:1-8. 2006
    ..This approach differs from current therapies, including antibiotics, in that it targets the pathogens which recognize these receptors...
  42. pmc HAMLET interacts with lipid membranes and perturbs their structure and integrity
    Ann Kristin Mossberg
    Section of Microbiology, Immunology, and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    PLoS ONE 5:e9384. 2010
    ..This study examined whether HAMLET interacts with artificial membranes and alters membrane structure...
  43. ncbi request reprint Bladder cancers respond to intravesical instillation of HAMLET (human alpha-lactalbumin made lethal to tumor cells)
    Ann Kristin Mossberg
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    Int J Cancer 121:1352-9. 2007
    ..The results suggest that HAMLET exerts a direct and selective effect on bladder cancer tissue in vivo and that local HAMLET administration might be of value in the future treatment of bladder cancers...
  44. ncbi request reprint alpha-Lactalbumin species variation, HAMLET formation, and tumor cell death
    Jenny Pettersson
    Department of Microbiology, Immunology and Glycobiology MIG, Institute of Laboratory Medicine, Lund University, Sweden
    Biochem Biophys Res Commun 345:260-70. 2006
    ..We conclude that structural variation of alpha-lactalbumins does not preclude the formation of HAMLET-like complexes and that natural HAMLET formation in casein was unique to human milk, which also showed the highest oleic acid content...
  45. ncbi request reprint Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid
    Lotta Gustafsson
    Institute of Laboratory Medicine, Department of Microbiology, Immunology, and Glycobiology, University of Lund, Lund, Sweden
    N Engl J Med 350:2663-72. 2004
    ....
  46. doi request reprint HAMLET treatment delays bladder cancer development
    Ann Kristin Mossberg
    Department of Microbiology, Institute of Laboratory Medicine, Lund University, Lund, Sweden
    J Urol 183:1590-7. 2010
    ..Recently we observed a rapid reduction in human bladder cancer size after intravesical HAMLET treatment. In this study we evaluated the therapeutic effect of HAMLET in the mouse MB49 bladder carcinoma model...
  47. ncbi request reprint Mechanism of pathogen-specific TLR4 activation in the mucosa: fimbriae, recognition receptors and adaptor protein selection
    Hans Fischer
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, S 22362 Lund, Sweden
    Eur J Immunol 36:267-77. 2006
    ..Thus, TLR4 may be engaged specifically by pathogens, when the proper cell surface receptors are engaged by virulence ligands...
  48. doi request reprint Do Escherichia coli strains causing acute cystitis have a distinct virulence repertoire?
    Birgit Stattin Norinder
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Solvegatan 23, SE 22362 Lund, Sweden
    Microb Pathog 52:10-6. 2012
    ..coli strains causing acute cystitis suggests that diverse bacterial strains, expressing Type 1 fimbriae trigger a convergent host response, involving pathways that give rise to the characteristic symptoms of acute cystitis...
  49. ncbi request reprint Glycolipid depletion in antimicrobial therapy
    Majlis Svensson
    Department of Laboratory Medicine, Division of Microbiology, Lund University, S 223 62 Lund, Sweden
    Mol Microbiol 47:453-61. 2003
    ..These results confirmed the role of P fimbriae-mediated adherence for colonization and inflammation and point to an interesting alternative to antibiotic treatment for urinary tract infection...
  50. ncbi request reprint Human renal epithelial cells express iNOS in response to cytokines but not bacteria
    Mirjana Poljakovic
    Department of Clinical Pharmacology, Lund University Hospital, Lund, Sweden
    Kidney Int 61:444-55. 2002
    ....
  51. pmc Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets through TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndrome
    Anne lie Ståhl
    Department of Pediatrics, Clinical Sciences Lund, the Institute of Laboratory Medicine, Section for Microbiology, Immunology and Glycobiology, Lund University, 22185 Lund, Sweden
    Blood 108:167-76. 2006
    ..These data suggest that O157LPS on platelets might contribute to platelet consumption in HUS...
  52. ncbi request reprint Genetics of innate immunity and UTI susceptibility
    Bryndis Ragnarsdottir
    Section of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Solvegatan 23, 22362 Lund, Sweden
    Nat Rev Urol 8:449-68. 2011
    ....
  53. ncbi request reprint The role of P fimbriae for Escherichia coli establishment and mucosal inflammation in the human urinary tract
    Bjorn Wullt
    Division of Clinical Immunology, Department of Laboratory Medicine, Lund University, Lund, Sweden
    Int J Antimicrob Agents 19:522-38. 2002
  54. ncbi request reprint Hamlet--a complex from human milk that induces apoptosis in tumor cells but spares healthy cells
    Malin Svensson
    Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Sweden
    Adv Exp Med Biol 503:125-32. 2002