Research Topics
Genomes and GenesSpecies | Christian RuckSummaryAffiliation: Lund University Country: Sweden Publications
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Publications
Capsulotomy for refractory anxiety disorders: long-term follow-up of 26 patientsChristian Ruck
Department of Clinical Neuroscience, Section of Psychiatry, Karolinska Institutet, Stockholm, Sweden
Am J Psychiatry 160:513-21. 2003..The objective of the present study was to evaluate the long-term efficacy and safety of capsulotomy in patients with anxiety disorders...
Internet-versus group-administered cognitive behaviour therapy for panic disorder in a psychiatric setting: a randomised trialJan Bergstrom
Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
BMC Psychiatry 10:54. 2010..The second aim of the study was to establish the cost-effectiveness of these interventions...
Acceptability, effectiveness, and cost-effectiveness of internet-based exposure treatment for irritable bowel syndrome in a clinical sample: a randomized controlled trialBrjann Ljotsson
Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
BMC Gastroenterol 11:110. 2011..We aimed to investigate the acceptability, effectiveness, and cost-effectiveness of ICBT for IBS using a consecutively recruited sample from a gastroenterological clinic...
Internet-based cognitive behavior therapy for obsessive compulsive disorder: a pilot studyErik Andersson
Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
BMC Psychiatry 11:125. 2011..Internet-based CBT (ICBT) with therapist support is a way to increase access to CBT but has not been developed or tested for OCD. The aim of this study was to evaluate ICBT for OCD...
Capsulotomy for obsessive-compulsive disorder: long-term follow-up of 25 patientsChristian Ruck
Section of Psychiatry M57, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Huddinge, SE 141 86 Stockholm, Sweden
Arch Gen Psychiatry 65:914-21. 2008..Capsulotomy is sometimes used as a treatment of last resort in severe and treatment-refractory cases of obsessive-compulsive disorder (OCD)...
Long-term follow-up of internet-delivered exposure and mindfulness based treatment for irritable bowel syndromeBrjann Ljotsson
Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
Behav Res Ther 49:58-61. 2011..This study suggests that internet-delivered CBT based on exposure and mindfulness has long-term beneficial effects for IBS-patients...
Cost-effectiveness of Internet-based cognitive behavior therapy vs. cognitive behavioral group therapy for social anxiety disorder: results from a randomized controlled trialErik Hedman
Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
Behav Res Ther 49:729-36. 2011..We conclude that ICBT can be more cost-effective than CBGT in the treatment of SAD and that both treatments reduce societal costs for SAD...
Internet-delivered exposure-based treatment vs. stress management for irritable bowel syndrome: a randomized trialBrjann Ljotsson
Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
Am J Gastroenterol 106:1481-91. 2011..We compared ICBT with internet-delivered stress management (ISM) for IBS to assess whether the effects of ICBT are specific...
Internet-based cognitive-behavioural therapy for severe health anxiety: randomised controlled trialErik Hedman
Karolinska Institutet, Department of Clinical Neuroscience, Stockholm, Sweden
Br J Psychiatry 198:230-6. 2011..Internet-based CBT, including guidance in the form of minimal therapist contact via email, could be a more accessible treatment, but no study has investigated internet-based CBT for hypochondriasis...
The COMTval158met polymorphism is associated with symptom relief during exposure-based cognitive-behavioral treatment in panic disorderTina B Lonsdorf
Psychology Section, Karolinska Institutet, Fogdevreten 2A, 17176 Stockholm, Sweden
BMC Psychiatry 10:99. 2010....
A 5-Year follow-up of internet-based cognitive behavior therapy for social anxiety disorderErik Hedman
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
J Med Internet Res 13:e39. 2011..Several trials have demonstrated that Internet-based CBT can be effective for SAD in the shorter term. However, the long-term effects of Internet-based CBT for SAD are less well known...
Internet-based cognitive behavior therapy vs. cognitive behavioral group therapy for social anxiety disorder: a randomized controlled non-inferiority trialErik Hedman
Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
PLoS ONE 6:e18001. 2011..Our aim was to investigate if ICBT is at least as effective as CBGT for SAD when treatments are delivered in a psychiatric setting...
Cost-effectiveness of internet-based cognitive behavior therapy for irritable bowel syndrome: results from a randomized controlled trialErik Andersson
Department of Clinical Neuroscience, Stockholm Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
BMC Public Health 11:215. 2011..The aim of this study was to evaluate the cost-effectiveness of a new treatment alternative, internet-delivered CBT based on exposure and mindfulness exercises...
Effectiveness and cost offset analysis of group CBT for hypochondriasis delivered in a psychiatric setting: an open trialErik Hedman
Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
Cogn Behav Ther 39:239-50. 2010..03-1.72). Medical and nonmedical costs were substantially lowered. The authors conclude that group-based CBT delivered in a psychiatric setting is an effective and potentially highly cost-effective treatment for hypochondriasis...
Exposure and mindfulness based therapy for irritable bowel syndrome--an open pilot studyBrjann Ljotsson
Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
J Behav Ther Exp Psychiatry 41:185-90. 2010..Treatment gains were maintained at follow-up. The results support the use of exposure and mindfulness based strategies in the treatment of IBS, but further randomised studies are needed to confirm the efficacy of the treatment...
Internet-delivered exposure and mindfulness based therapy for irritable bowel syndrome--a randomized controlled trialBrjann Ljotsson
Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, University Hospital Huddinge, Stockholm, Sweden
Behav Res Ther 48:531-9. 2010..21). We conclude that CBT-based on exposure and mindfulness delivered via the Internet can be effective in treating IBS-patients, alleviating the total burden of symptoms and increasing quality of life...
Self-rated versus family-rated personality in patients undergoing capsulotomy for obsessive-compulsive disorderChristian Ruck
Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
Nord J Psychiatry 64:239-44. 2010..The Karolinska Scales of Personality (KSP) is a self-rated personality inventory. The validity of an observer-rated version of the KSP in unknown...
Lesion topography in capsulotomy for refractory anxiety--is the right side the right side?Christian Ruck
Section for Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
Stereotact Funct Neurosurg 83:172-9. 2005..The aims of the present study were to test if the same region was involved in anxiety patients responding to surgery and to examine whether lesion area and site correlated with adverse events and effect on target symptoms...
Long-term changes in self-reported personality following capsulotomy in anxiety patientsChristian Ruck
Department of Clinical Neuroscience, Section for Psychiatry, Karolinska Institutet, Stockholm, Sweden
Nord J Psychiatry 60:486-91. 2006..The conclusion based on previous KSP findings that the incidence of adverse personality changes following capsulotomy is low and does not increase with time is challenged by the present study...
The symptomatic profile of panic disorder is shaped by the 5-HTTLPR polymorphismTina B Lonsdorf
Department of Clinical Neuroscience, Psychology Section, Karolinska Institutet, Stockholm, Sweden
Prog Neuropsychopharmacol Biol Psychiatry 33:1479-83. 2009....
An open study of the effectiveness of Internet treatment for panic disorder delivered in a psychiatric settingJan Bergstrom
Department of Clinical Neuroscience, Section of Psychiatry, Karolinska Institutet, Stockholm, Sweden
Nord J Psychiatry 63:44-50. 2009..However, a larger randomized controlled trial should be conducted, directly comparing Internet-based CBT with traditionally administered CBT within such a setting...
Predictors of medium and long-term outcome following capsulotomy for obsessive-compulsive disorder: one site may not fit allChristian Ruck
Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
Eur Neuropsychopharmacol 22:406-14. 2012..The results could have implications for existing ablative and deep brain stimulation protocols and challenge our current conceptualization of OCD as a unitary diagnostic entity with a single neurobiological substrate...
A stepped care strategy using buprenorphine and methadone versus conventional methadone maintenance in heroin dependence: a randomized controlled trialJohan Kakko
Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
Am J Psychiatry 164:797-803. 2007..Buprenorphine offers lower overdose risk and improved access, but efficacy may be lower. The authors compared adaptive, buprenorphine-based stepped care to optimal methadone maintenance treatment...
Selective serotonin reuptake inhibitors and the risk of acute pancreatitis: a Swedish population-based case-control studyRickard Ljung
Upper Gastrointestinal Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
J Clin Psychopharmacol 32:336-40. 2012..0 (95% CI, 0.9-1.1). The OR for antidepressant use other than SSRI showed a similar pattern. In conclusion, no increased risk of acute pancreatitis remained among users of SSRI after adjusting for confounding factors...
