Christian Ruck

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. ncbi request reprint Capsulotomy for refractory anxiety disorders: long-term follow-up of 26 patients
    Christian Ruck
    Department of Clinical Neuroscience, Section of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Am J Psychiatry 160:513-21. 2003
  2. pmc Internet-versus group-administered cognitive behaviour therapy for panic disorder in a psychiatric setting: a randomised trial
    Jan Bergstrom
    Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
    BMC Psychiatry 10:54. 2010
  3. pmc Acceptability, effectiveness, and cost-effectiveness of internet-based exposure treatment for irritable bowel syndrome in a clinical sample: a randomized controlled trial
    Brjann Ljotsson
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    BMC Gastroenterol 11:110. 2011
  4. doi request reprint Capsulotomy for obsessive-compulsive disorder: long-term follow-up of 25 patients
    Christian Ruck
    Section of Psychiatry M57, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Huddinge, SE 141 86 Stockholm, Sweden
    Arch Gen Psychiatry 65:914-21. 2008
  5. pmc Internet-based cognitive behavior therapy for obsessive compulsive disorder: a pilot study
    Erik Andersson
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    BMC Psychiatry 11:125. 2011
  6. doi request reprint Long-term follow-up of internet-delivered exposure and mindfulness based treatment for irritable bowel syndrome
    Brjann Ljotsson
    Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Behav Res Ther 49:58-61. 2011
  7. doi request reprint Cost-effectiveness of Internet-based cognitive behavior therapy vs. cognitive behavioral group therapy for social anxiety disorder: results from a randomized controlled trial
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Behav Res Ther 49:729-36. 2011
  8. pmc Genetic polymorphisms in monoamine systems and outcome of cognitive behavior therapy for social anxiety disorder
    Evelyn Andersson
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e79015. 2013
  9. doi request reprint Internet-delivered exposure-based treatment vs. stress management for irritable bowel syndrome: a randomized trial
    Brjann Ljotsson
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Am J Gastroenterol 106:1481-91. 2011
  10. doi request reprint Internet-based cognitive-behavioural therapy for severe health anxiety: randomised controlled trial
    Erik Hedman
    Karolinska Institutet, Department of Clinical Neuroscience, Stockholm, Sweden
    Br J Psychiatry 198:230-6. 2011

Detail Information

Publications36

  1. ncbi request reprint Capsulotomy for refractory anxiety disorders: long-term follow-up of 26 patients
    Christian Ruck
    Department of Clinical Neuroscience, Section of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Am J Psychiatry 160:513-21. 2003
    ..The objective of the present study was to evaluate the long-term efficacy and safety of capsulotomy in patients with anxiety disorders...
  2. pmc Internet-versus group-administered cognitive behaviour therapy for panic disorder in a psychiatric setting: a randomised trial
    Jan Bergstrom
    Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
    BMC Psychiatry 10:54. 2010
    ..The second aim of the study was to establish the cost-effectiveness of these interventions...
  3. pmc Acceptability, effectiveness, and cost-effectiveness of internet-based exposure treatment for irritable bowel syndrome in a clinical sample: a randomized controlled trial
    Brjann Ljotsson
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    BMC Gastroenterol 11:110. 2011
    ..We aimed to investigate the acceptability, effectiveness, and cost-effectiveness of ICBT for IBS using a consecutively recruited sample from a gastroenterological clinic...
  4. doi request reprint Capsulotomy for obsessive-compulsive disorder: long-term follow-up of 25 patients
    Christian Ruck
    Section of Psychiatry M57, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Huddinge, SE 141 86 Stockholm, Sweden
    Arch Gen Psychiatry 65:914-21. 2008
    ..Capsulotomy is sometimes used as a treatment of last resort in severe and treatment-refractory cases of obsessive-compulsive disorder (OCD)...
  5. pmc Internet-based cognitive behavior therapy for obsessive compulsive disorder: a pilot study
    Erik Andersson
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    BMC Psychiatry 11:125. 2011
    ..Internet-based CBT (ICBT) with therapist support is a way to increase access to CBT but has not been developed or tested for OCD. The aim of this study was to evaluate ICBT for OCD...
  6. doi request reprint Long-term follow-up of internet-delivered exposure and mindfulness based treatment for irritable bowel syndrome
    Brjann Ljotsson
    Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Behav Res Ther 49:58-61. 2011
    ..This study suggests that internet-delivered CBT based on exposure and mindfulness has long-term beneficial effects for IBS-patients...
  7. doi request reprint Cost-effectiveness of Internet-based cognitive behavior therapy vs. cognitive behavioral group therapy for social anxiety disorder: results from a randomized controlled trial
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Behav Res Ther 49:729-36. 2011
    ..We conclude that ICBT can be more cost-effective than CBGT in the treatment of SAD and that both treatments reduce societal costs for SAD...
  8. pmc Genetic polymorphisms in monoamine systems and outcome of cognitive behavior therapy for social anxiety disorder
    Evelyn Andersson
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e79015. 2013
    ..The aim of the present study was to investigate if these three gene variants predicted response to CBT in a large sample of SAD patients...
  9. doi request reprint Internet-delivered exposure-based treatment vs. stress management for irritable bowel syndrome: a randomized trial
    Brjann Ljotsson
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Am J Gastroenterol 106:1481-91. 2011
    ..We compared ICBT with internet-delivered stress management (ISM) for IBS to assess whether the effects of ICBT are specific...
  10. doi request reprint Internet-based cognitive-behavioural therapy for severe health anxiety: randomised controlled trial
    Erik Hedman
    Karolinska Institutet, Department of Clinical Neuroscience, Stockholm, Sweden
    Br J Psychiatry 198:230-6. 2011
    ..Internet-based CBT, including guidance in the form of minimal therapist contact via email, could be a more accessible treatment, but no study has investigated internet-based CBT for hypochondriasis...
  11. pmc The COMTval158met polymorphism is associated with symptom relief during exposure-based cognitive-behavioral treatment in panic disorder
    Tina B Lonsdorf
    Psychology Section, Karolinska Institutet, Fogdevreten 2A, 17176 Stockholm, Sweden
    BMC Psychiatry 10:99. 2010
    ....
  12. pmc A 5-Year follow-up of internet-based cognitive behavior therapy for social anxiety disorder
    Erik Hedman
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Med Internet Res 13:e39. 2011
    ..Several trials have demonstrated that Internet-based CBT can be effective for SAD in the shorter term. However, the long-term effects of Internet-based CBT for SAD are less well known...
  13. pmc Mediators in internet-based cognitive behavior therapy for severe health anxiety
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e77752. 2013
    ..The findings have theoretical and clinical implications as they indicate processes that may be causally related to the improvements observed after CBT for health anxiety. ..
  14. pmc Telephone versus internet administration of self-report measures of social anxiety, depressive symptoms, and insomnia: psychometric evaluation of a method to reduce the impact of missing data
    Erik Hedman
    Osher Center for Integrative Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Med Internet Res 15:e229. 2013
    ..One way of reducing the negative impact of missing data could be to use telephone administration of self-report measures as a means to complete the data missing from the online data collection...
  15. doi request reprint Effectiveness of Internet-based cognitive behaviour therapy for depression in routine psychiatric care
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Sweden Department of Clinical Neuroscience, Osher Center for Integrative Medicine Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    J Affect Disord 155:49-58. 2014
    ..Knowledge on the effectiveness of the treatment, i.e. how it works when delivered within routine care, is however scarce. The aim of this study was to investigate the effectiveness of ICBT for depression...
  16. doi request reprint Mechanisms of change in an exposure-based treatment for irritable bowel syndrome
    Brjann Ljotsson
    Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet
    J Consult Clin Psychol 81:1113-26. 2013
    ..The original study found that ICBT was more effective than ISM in improving IBS symptoms...
  17. pmc Cost-effectiveness of internet-based cognitive behavior therapy for irritable bowel syndrome: results from a randomized controlled trial
    Erik Andersson
    Department of Clinical Neuroscience, Stockholm Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
    BMC Public Health 11:215. 2011
    ..The aim of this study was to evaluate the cost-effectiveness of a new treatment alternative, internet-delivered CBT based on exposure and mindfulness exercises...
  18. pmc Internet-based cognitive behavior therapy vs. cognitive behavioral group therapy for social anxiety disorder: a randomized controlled non-inferiority trial
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 6:e18001. 2011
    ..Our aim was to investigate if ICBT is at least as effective as CBGT for SAD when treatments are delivered in a psychiatric setting...
  19. pmc Predictors and moderators of internet- and group-based cognitive behaviour therapy for panic disorder
    Samir El Alaoui
    Karolinska Institutet, Department of Clinical Neuroscience, Division of Psychiatry, Stockholm, Sweden
    PLoS ONE 8:e79024. 2013
    ..These results suggest that both ICBT and GCBT are effective treatment modalities for PD and that it is possible to predict a significant proportion of the long-term outcome variance based on clinical variables. ..
  20. doi request reprint Effectiveness and cost offset analysis of group CBT for hypochondriasis delivered in a psychiatric setting: an open trial
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Cogn Behav Ther 39:239-50. 2010
    ..03-1.72). Medical and nonmedical costs were substantially lowered. The authors conclude that group-based CBT delivered in a psychiatric setting is an effective and potentially highly cost-effective treatment for hypochondriasis...
  21. doi request reprint Exposure and mindfulness based therapy for irritable bowel syndrome--an open pilot study
    Brjann Ljotsson
    Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Behav Ther Exp Psychiatry 41:185-90. 2010
    ..Treatment gains were maintained at follow-up. The results support the use of exposure and mindfulness based strategies in the treatment of IBS, but further randomised studies are needed to confirm the efficacy of the treatment...
  22. pmc Sudden gains in internet-based cognitive behaviour therapy for severe health anxiety
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    Behav Res Ther 54:22-9. 2014
    ..The aim of this study was to investigate the role of sudden gains in internet-based cognitive behavioural therapy for severe health anxiety...
  23. doi request reprint Internet-delivered exposure and mindfulness based therapy for irritable bowel syndrome--a randomized controlled trial
    Brjann Ljotsson
    Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, University Hospital Huddinge, Stockholm, Sweden
    Behav Res Ther 48:531-9. 2010
    ..21). We conclude that CBT-based on exposure and mindfulness delivered via the Internet can be effective in treating IBS-patients, alleviating the total burden of symptoms and increasing quality of life...
  24. doi request reprint Self-rated versus family-rated personality in patients undergoing capsulotomy for obsessive-compulsive disorder
    Christian Ruck
    Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
    Nord J Psychiatry 64:239-44. 2010
    ..The Karolinska Scales of Personality (KSP) is a self-rated personality inventory. The validity of an observer-rated version of the KSP in unknown...
  25. doi request reprint Predictors of outcome in Internet-based cognitive behavior therapy for severe health anxiety
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Retzius vag 8, SE 171 77 Stockholm, Sweden Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    Behav Res Ther 51:711-7. 2013
    ..We conclude that baseline symptom burden and adherence to treatment have strong predictive effects in Internet-based CBT for severe health anxiety...
  26. doi request reprint An open study of the effectiveness of Internet treatment for panic disorder delivered in a psychiatric setting
    Jan Bergstrom
    Department of Clinical Neuroscience, Section of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Nord J Psychiatry 63:44-50. 2009
    ..However, a larger randomized controlled trial should be conducted, directly comparing Internet-based CBT with traditionally administered CBT within such a setting...
  27. doi request reprint The symptomatic profile of panic disorder is shaped by the 5-HTTLPR polymorphism
    Tina B Lonsdorf
    Department of Clinical Neuroscience, Psychology Section, Karolinska Institutet, Stockholm, Sweden
    Prog Neuropsychopharmacol Biol Psychiatry 33:1479-83. 2009
    ....
  28. ncbi request reprint Long-term changes in self-reported personality following capsulotomy in anxiety patients
    Christian Ruck
    Department of Clinical Neuroscience, Section for Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Nord J Psychiatry 60:486-91. 2006
    ..The conclusion based on previous KSP findings that the incidence of adverse personality changes following capsulotomy is low and does not increase with time is challenged by the present study...
  29. ncbi request reprint Lesion topography in capsulotomy for refractory anxiety--is the right side the right side?
    Christian Ruck
    Section for Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Stereotact Funct Neurosurg 83:172-9. 2005
    ..The aims of the present study were to test if the same region was involved in anxiety patients responding to surgery and to examine whether lesion area and site correlated with adverse events and effect on target symptoms...
  30. pmc Internet-delivered cognitive behavior therapy for adolescents with obsessive-compulsive disorder: an open trial
    Fabian Lenhard
    Department of Clinical Neuroscience, Centre for Psychiatric Research and Education, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 9:e100773. 2014
    ..We developed and tested the feasibility, efficacy and acceptability of a novel therapist-guided, Internet-delivered CBT (ICBT) platform for adolescents with OCD...
  31. pmc Using Early Change to Predict Outcome in Cognitive Behaviour Therapy: Exploring Timeframe, Calculation Method, and Differences of Disorder-Specific versus General Measures
    Peter Schibbye
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden Section of Psychiatry, Sundsvall Härnösand County Hospital, Vasternorrland County Council, Sweden
    PLoS ONE 9:e100614. 2014
    ..We conclude that a simple calculation method with a disorder-specific measure at week four seems to provide a good choice for predicting outcome in time-limited cognitive behavior therapy. ..
  32. doi request reprint Predictors of medium and long-term outcome following capsulotomy for obsessive-compulsive disorder: one site may not fit all
    Christian Ruck
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Eur Neuropsychopharmacol 22:406-14. 2012
    ..The results could have implications for existing ablative and deep brain stimulation protocols and challenge our current conceptualization of OCD as a unitary diagnostic entity with a single neurobiological substrate...
  33. ncbi request reprint A stepped care strategy using buprenorphine and methadone versus conventional methadone maintenance in heroin dependence: a randomized controlled trial
    Johan Kakko
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    Am J Psychiatry 164:797-803. 2007
    ..Buprenorphine offers lower overdose risk and improved access, but efficacy may be lower. The authors compared adaptive, buprenorphine-based stepped care to optimal methadone maintenance treatment...
  34. ncbi request reprint Reduced 5-HT1B receptor binding in the dorsal brain stem after cognitive behavioural therapy of major depressive disorder
    Mikael Tiger
    Department of Clinical Neuroscience, Karolinska Institutet, Centrum för psykiatriforskning, R5 0, Karolinska Universitetssjukhuset i Solna, 171 76 Stockholm, Sweden Electronic address
    Psychiatry Res 223:164-70. 2014
    ..The DBS contains the raphe nuclei, which regulate the serotonin system. This study gives support for the importance of serotonin and the 5-HT1B receptor in the biological response to psychological treatment of MDD. ..
  35. pmc Prevalence, comorbidity and heritability of hoarding symptoms in adolescence: a population based twin study in 15-year olds
    Volen Z Ivanov
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e69140. 2013
    ..We examined the prevalence, comorbidity and etiology of hoarding symptoms in adolescence...
  36. doi request reprint Selective serotonin reuptake inhibitors and the risk of acute pancreatitis: a Swedish population-based case-control study
    Rickard Ljung
    Upper Gastrointestinal Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    J Clin Psychopharmacol 32:336-40. 2012
    ..0 (95% CI, 0.9-1.1). The OR for antidepressant use other than SSRI showed a similar pattern. In conclusion, no increased risk of acute pancreatitis remained among users of SSRI after adjusting for confounding factors...