Thomas M Reinbothe


Affiliation: Lund University
Country: Sweden


  1. Reinbothe T, Ivarsson R, Li D, Niazi O, Jing X, Zhang E, et al. Glutaredoxin-1 mediates NADPH-dependent stimulation of calcium-dependent insulin secretion. Mol Endocrinol. 2009;23:893-900 pubmed publisher
    ..This effect is mediated by the NADPH acceptor protein GRX-1 by a local redox reaction that accelerates beta-cell exocytosis and, in turn, insulin secretion. ..
  2. Reinbothe T, Alkayyali S, Ahlqvist E, Tuomi T, Isomaa B, Lyssenko V, et al. The human L-type calcium channel Cav1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes. Diabetologia. 2013;56:340-9 pubmed publisher
    ..We conclude that the L-type calcium channel Cav1.3 is important in human glucose-induced insulin secretion, and common variants in CACNA1D might contribute to type 2 diabetes. ..