- Ticagrelor induces adenosine triphosphate release from human red blood cellsJenny Ohman
Department of Cardiology, Lund University, Lund, Sweden
Biochem Biophys Res Commun 418:754-8. 2012..Clinical trials have revealed dyspnea and asymptomatic ventricular pauses as side effects of ticagrelor. The mechanism behind these side effects is not known, but it is plausible that they are mediated by adenosine...
- The antimicrobial peptide LL-37 alters human osteoblast Ca2+ handling and induces Ca2+-independent apoptosisJohanna Säll
Department of Experimental Medical Science, Lund University, Lund, Sweden
J Innate Immun 5:290-300. 2013..Interestingly, LL-37-induced lowering of the cell number seems to be mediated via a mechanism independent of Ca(2+)...
- Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expressionOlof Gidlöf
Department of Cardiology, Faculty of Medicine, Lund University, Lund, Sweden
Blood 121:3908-17, S1-26. 2013..Thus, platelets from patients with MI exhibit loss of specific miRNAs, and activated platelets shed miRNAs that can regulate endothelial cell gene expression...