L Ohlsson

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. ncbi request reprint Psyllium and fat in diets differentially affect the activities and expressions of colonic sphingomyelinases and caspase in mice
    Yajun Cheng
    Gastroenterology and Nutrition Laboratory, Biomedical Centre, B11, Lund University, S 22184 Lund, Sweden
    Br J Nutr 91:715-23. 2004
  2. pmc Postprandial lipid responses to an alpha-linolenic acid-rich oil, olive oil and butter in women: a randomized crossover trial
    Julia Svensson
    1Department of Biotechnology, Lund University, P O Box 124, SE 22100 Lund, Sweden
    Lipids Health Dis 10:106. 2011
  3. pmc Curcumin inhibits cholesterol uptake in Caco-2 cells by down-regulation of NPC1L1 expression
    Dan Feng
    Gastroenterology and Nutrition Laboratory, Biomedical Center B11, Institution of Clinical Sciences, University of Lund, Lund, Sweden
    Lipids Health Dis 9:40. 2010
  4. doi request reprint Expression of intestinal and lung alkaline sphingomyelinase and neutral ceramidase in cystic fibrosis f508del transgenic mice
    Lena Ohlsson
    Department of Clinical Sciences, Medicine Gastroenterology and Nutrition, Lund University Hospital, Lund, Sweden
    J Pediatr Gastroenterol Nutr 47:547-54. 2008
  5. doi request reprint Effects of a sphingolipid-enriched dairy formulation on postprandial lipid concentrations
    L Ohlsson
    Department of Clinical Sciences, Medicine Gastroenterology and Nutrition, Lund University Hospital, Lund, Sweden
    Eur J Clin Nutr 64:1344-9. 2010
  6. ncbi request reprint Purification and characterization of human intestinal neutral ceramidase
    Lena Ohlsson
    Gastroenterology and Nutrition Laboratory, Biomedical Centre B11, Lund University, Tornavagen 10, S 22184 Lund, Sweden
    Biochimie 89:950-60. 2007
  7. pmc Long term effects on human plasma lipoproteins of a formulation enriched in butter milk polar lipid
    Lena Ohlsson
    Department of Clinical Sciences, Medicine Gastroenterology and Nutrition, Lund University Hospital, S221 85 Lund, Sweden
    Lipids Health Dis 8:44. 2009
  8. ncbi request reprint Evidence for specific ceramidase present in the intestinal contents of rats and humans
    R D Duan
    Department of Cell Biology B, Biomedical Center, University of Lund, Sweden
    Lipids 36:807-12. 2001
  9. doi request reprint Sphingolipids in human ileostomy content after meals containing milk sphingomyelin
    Lena Ohlsson
    Department of Gastroenterology, Lund University, Lund, Sweden
    Am J Clin Nutr 91:672-8. 2010
  10. ncbi request reprint Rat intestinal ceramidase: purification, properties, and physiological relevance
    Maria Olsson
    Dept of Medicine, Gastroenterology and Nutrition Laboratory, BMC B11, Lund Univ Hospital, S 22184 Lunds Universitet, Sweden
    Am J Physiol Gastrointest Liver Physiol 287:G929-37. 2004

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Psyllium and fat in diets differentially affect the activities and expressions of colonic sphingomyelinases and caspase in mice
    Yajun Cheng
    Gastroenterology and Nutrition Laboratory, Biomedical Centre, B11, Lund University, S 22184 Lund, Sweden
    Br J Nutr 91:715-23. 2004
    ..In conclusion, colonic sphingomyelin metabolism and apoptosis were affected by psyllium and fat in an opposite manner. The results may have implications for colorectal tumourigenesis and inflammation...
  2. pmc Postprandial lipid responses to an alpha-linolenic acid-rich oil, olive oil and butter in women: a randomized crossover trial
    Julia Svensson
    1Department of Biotechnology, Lund University, P O Box 124, SE 22100 Lund, Sweden
    Lipids Health Dis 10:106. 2011
    ....
  3. pmc Curcumin inhibits cholesterol uptake in Caco-2 cells by down-regulation of NPC1L1 expression
    Dan Feng
    Gastroenterology and Nutrition Laboratory, Biomedical Center B11, Institution of Clinical Sciences, University of Lund, Lund, Sweden
    Lipids Health Dis 9:40. 2010
    ....
  4. doi request reprint Expression of intestinal and lung alkaline sphingomyelinase and neutral ceramidase in cystic fibrosis f508del transgenic mice
    Lena Ohlsson
    Department of Clinical Sciences, Medicine Gastroenterology and Nutrition, Lund University Hospital, Lund, Sweden
    J Pediatr Gastroenterol Nutr 47:547-54. 2008
    ..In this study, we tested the hypothesis that the expression of these enzymes is different in CF...
  5. doi request reprint Effects of a sphingolipid-enriched dairy formulation on postprandial lipid concentrations
    L Ohlsson
    Department of Clinical Sciences, Medicine Gastroenterology and Nutrition, Lund University Hospital, Lund, Sweden
    Eur J Clin Nutr 64:1344-9. 2010
    ..The digestion of sphingolipids (SL) is slow and is catalyzed by mucosal enzymes. Dietary SL was shown to inhibit cholesterol absorption and to lower plasma cholesterol, triglycerides (TG) and hepatic fat accumulation in animal models...
  6. ncbi request reprint Purification and characterization of human intestinal neutral ceramidase
    Lena Ohlsson
    Gastroenterology and Nutrition Laboratory, Biomedical Centre B11, Lund University, Tornavagen 10, S 22184 Lund, Sweden
    Biochimie 89:950-60. 2007
    ..Our study indicates that neutral ceramidase is expressed in human intestine, released in the intestinal lumen and plays a major role in ceramide metabolism in the human gut...
  7. pmc Long term effects on human plasma lipoproteins of a formulation enriched in butter milk polar lipid
    Lena Ohlsson
    Department of Clinical Sciences, Medicine Gastroenterology and Nutrition, Lund University Hospital, S221 85 Lund, Sweden
    Lipids Health Dis 8:44. 2009
    ..The daily dose of SL in A was 975 mg of which 700 mg was SM. The participants registered food and drink intake four days before introducing the test formula and the last four days of the test period...
  8. ncbi request reprint Evidence for specific ceramidase present in the intestinal contents of rats and humans
    R D Duan
    Department of Cell Biology B, Biomedical Center, University of Lund, Sweden
    Lipids 36:807-12. 2001
    ..In conclusion, we provide the evidence for a specific ceramidase other than pancreatic BSSL present in the intestinal content. The enzyme may play important roles in digestion of dietary sphingolipids...
  9. doi request reprint Sphingolipids in human ileostomy content after meals containing milk sphingomyelin
    Lena Ohlsson
    Department of Gastroenterology, Lund University, Lund, Sweden
    Am J Clin Nutr 91:672-8. 2010
    ..In humans, alkaline sphingomyelinase is also secreted in bile. The digestion of sphingomyelin is slow and incomplete, which has been linked to the inhibition of cholesterol absorption and colonic carcinogenesis...
  10. ncbi request reprint Rat intestinal ceramidase: purification, properties, and physiological relevance
    Maria Olsson
    Dept of Medicine, Gastroenterology and Nutrition Laboratory, BMC B11, Lund Univ Hospital, S 22184 Lunds Universitet, Sweden
    Am J Physiol Gastrointest Liver Physiol 287:G929-37. 2004
    ..It is well suited to metabolize ceramide formed from dietary and brush border sphingolipids to generate other bioactive sphingolipid messengers...
  11. doi request reprint Glucose-lowering effect of the DPP-4 inhibitor sitagliptin after glucose and non-glucose macronutrient ingestion in non-diabetic subjects
    L Ohlsson
    Department of Clinical Sciences Lund, Lund University, Lund, Sweden
    Diabetes Obes Metab 15:531-7. 2013
    ..We therefore hypothesized that raising incretin hormones reduces circulating glucose after both glucose and non-glucose macronutrient ingestion in healthy subjects...
  12. ncbi request reprint Human meconium contains significant amounts of alkaline sphingomyelinase, neutral ceramidase, and sphingolipid metabolites
    Rui Dong Duan
    Department of Clinical Sciences, Medicine Gastroenterology and Nutrition, Lund University Hospital, Lund, Sweden
    Pediatr Res 61:61-6. 2007
    ..In conclusion, Alk-SMase and ceramidase are expressed in the gut of both preterm and term newborn infants and may generate bioactive sphingolipid messengers...
  13. ncbi request reprint Curcumin decreases acid sphingomyelinase activity in colon cancer Caco-2 cells
    Yajun Cheng
    Biomedical Centre, B11, Institution of Clinical Sciences, Lund University, Lund, Sweden
    Planta Med 73:725-30. 2007
    ..In conclusion, curcumin inhibits acid sphingomyelinase and the effect might be involved in its antiproliferative property against colon cancer cells...