Henrietta M Nielsen

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. ncbi Soluble adhesion molecules and angiotensin-converting enzyme in dementia
    Henrietta M Nielsen
    Chronic Inflammatory and Degenerative Disease Research Unit, Department of Clinical Sciences, Lund University, 205 02 Malmo, Sweden
    Neurobiol Dis 26:27-35. 2007
  2. ncbi Astrocytic A beta 1-42 uptake is determined by A beta-aggregation state and the presence of amyloid-associated proteins
    Henrietta M Nielsen
    Department of Clinical Chemistry, VU University Medical Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    Glia 58:1235-46. 2010
  3. doi Binding and uptake of A beta1-42 by primary human astrocytes in vitro
    Henrietta M Nielsen
    Department of Clinical Chemistry, Pathology, The Alzheimer Centre, VU University Medical Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    Glia 57:978-88. 2009
  4. pmc Low CSF levels of both α-synuclein and the α-synuclein cleaving enzyme neurosin in patients with synucleinopathy
    Malin Wennström
    Lund University, Department of Clinical Sciences Malmo, Molecular Memory Research Unit, The Wallenberg Laboratory at Skåne University Hospital, Malmo, Sweden
    PLoS ONE 8:e53250. 2013
  5. ncbi Cerebrospinal fluid inflammatory markers in Parkinson's disease--associations with depression, fatigue, and cognitive impairment
    Daniel Lindqvist
    Department of Clinical Sciences, Section for Psychiatry, Lund University, Lund, Sweden Psychiatry Skåne, Lund, Sweden Electronic address
    Brain Behav Immun 33:183-9. 2013
  6. doi Altered CSF orexin and α-synuclein levels in dementia patients
    Malin Wennström
    Molecular Memory Research Unit, The Wallenberg Laboratory, Skåne University Hospital SUS Malmö, Department of Clinical Sciences Malmo, Lund University, Malmo, Sweden
    J Alzheimers Dis 29:125-32. 2012
  7. doi The effect of amyloid associated proteins on the expression of genes involved in amyloid-β clearance by adult human astrocytes
    Sandra D Mulder
    Department of Clinical Chemistry, The Alzheimer Center, VU University Medical Center Amsterdam, P O Box 7057, 1007 MB Amsterdam, The Netherlands
    Exp Neurol 233:373-9. 2012
  8. doi C4b-binding protein in Alzheimer's disease: binding to Abeta1-42 and to dead cells
    Leendert A Trouw
    Department of Laboratory Medicine, Lund University, Malmo, Sweden
    Mol Immunol 45:3649-60. 2008
  9. doi Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitro
    Sandra D Mulder
    Department of Clinical Chemistry, VU University Medical Center, Amsterdam, The Netherlands Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands
    Glia 62:493-503. 2014
  10. pmc Complement in the brain
    Robert Veerhuis
    Department of Clinical Chemistry, VU University Medical Center, Amsterdam, The Netherlands
    Mol Immunol 48:1592-603. 2011

Detail Information

Publications10

  1. ncbi Soluble adhesion molecules and angiotensin-converting enzyme in dementia
    Henrietta M Nielsen
    Chronic Inflammatory and Degenerative Disease Research Unit, Department of Clinical Sciences, Lund University, 205 02 Malmo, Sweden
    Neurobiol Dis 26:27-35. 2007
    ..The observed patterns in adhesion molecules may reflect distinctions in the pathophysiological basis of their generation in dementia patients...
  2. ncbi Astrocytic A beta 1-42 uptake is determined by A beta-aggregation state and the presence of amyloid-associated proteins
    Henrietta M Nielsen
    Department of Clinical Chemistry, VU University Medical Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    Glia 58:1235-46. 2010
    ..Thus, amyloid-associated proteins, especially ApoJ and ApoE, can alter A beta-uptake in vitro and hence may influence A beta clearance and plaque formation in vivo...
  3. doi Binding and uptake of A beta1-42 by primary human astrocytes in vitro
    Henrietta M Nielsen
    Department of Clinical Chemistry, Pathology, The Alzheimer Centre, VU University Medical Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    Glia 57:978-88. 2009
    ..Thus, primary human astrocytes derived from different sources can bind and internalize A beta1-42, and fetal astrocytes were more efficient in A beta1-42 uptake than adult astrocytes...
  4. pmc Low CSF levels of both α-synuclein and the α-synuclein cleaving enzyme neurosin in patients with synucleinopathy
    Malin Wennström
    Lund University, Department of Clinical Sciences Malmo, Molecular Memory Research Unit, The Wallenberg Laboratory at Skåne University Hospital, Malmo, Sweden
    PLoS ONE 8:e53250. 2013
    ....
  5. ncbi Cerebrospinal fluid inflammatory markers in Parkinson's disease--associations with depression, fatigue, and cognitive impairment
    Daniel Lindqvist
    Department of Clinical Sciences, Section for Psychiatry, Lund University, Lund, Sweden Psychiatry Skåne, Lund, Sweden Electronic address
    Brain Behav Immun 33:183-9. 2013
    ..032). Our results indicate that non-motor features of PD such as depression, fatigue, and cognitive impairment are associated with higher CSF levels of inflammatory markers. ..
  6. doi Altered CSF orexin and α-synuclein levels in dementia patients
    Malin Wennström
    Molecular Memory Research Unit, The Wallenberg Laboratory, Skåne University Hospital SUS Malmö, Department of Clinical Sciences Malmo, Lund University, Malmo, Sweden
    J Alzheimers Dis 29:125-32. 2012
    ..Alterations in CSF orexin and α-synuclein levels may be related to gender which warrants further investigation...
  7. doi The effect of amyloid associated proteins on the expression of genes involved in amyloid-β clearance by adult human astrocytes
    Sandra D Mulder
    Department of Clinical Chemistry, The Alzheimer Center, VU University Medical Center Amsterdam, P O Box 7057, 1007 MB Amsterdam, The Netherlands
    Exp Neurol 233:373-9. 2012
    ..These astrocytic gene expression-regulatory mechanisms appear to be defective in AD and thus might contribute to the development and progression of AD pathology...
  8. doi C4b-binding protein in Alzheimer's disease: binding to Abeta1-42 and to dead cells
    Leendert A Trouw
    Department of Laboratory Medicine, Lund University, Malmo, Sweden
    Mol Immunol 45:3649-60. 2008
    ..In conclusion, C4BP binds to dead brain cells and Abeta peptide in vitro, is present in CSF and possibly protects against excessive complement activation in AD brains...
  9. doi Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitro
    Sandra D Mulder
    Department of Clinical Chemistry, VU University Medical Center, Amsterdam, The Netherlands Alzheimer Center, VU University Medical Center, Amsterdam, The Netherlands
    Glia 62:493-503. 2014
    ..Thus, targeting the association of Aβ with AAPs, such as ApoE and ApoJ, could serve as a therapeutic strategy to increase Aβ clearance by glial cells...
  10. pmc Complement in the brain
    Robert Veerhuis
    Department of Clinical Chemistry, VU University Medical Center, Amsterdam, The Netherlands
    Mol Immunol 48:1592-603. 2011
    ....