Aida Maddahi

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. pmc Regulation of enhanced cerebrovascular expression of proinflammatory mediators in experimental subarachnoid hemorrhage via the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathway
    Aida Maddahi
    Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, Lund, Sweden
    J Neuroinflammation 9:274. 2012
  2. pmc Enhanced expressions of microvascular smooth muscle receptors after focal cerebral ischemia occur via the MAPK MEK/ERK pathway
    Aida Maddahi
    Division of Experimental Vascular Research, BMC A13, Lund University, 221 84 Lund, Sweden
    BMC Neurosci 9:85. 2008
  3. pmc Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat
    Aida Maddahi
    Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, Lund, Sweden
    BMC Neurosci 10:56. 2009
  4. pmc The role of tumor necrosis factor-α and TNF-α receptors in cerebral arteries following cerebral ischemia in rat
    Aida Maddahi
    Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, Lund, Sweden
    J Neuroinflammation 8:107. 2011
  5. pmc Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway
    Aida Maddahi
    Department of Internal Medicine, Institute of Clinical Sciences, Lund University, Sweden
    J Neuroinflammation 7:14. 2010
  6. pmc Blockade of the MEK/ERK pathway with a raf inhibitor prevents activation of pro-inflammatory mediators in cerebral arteries and reduction in cerebral blood flow after subarachnoid hemorrhage in a rat model
    Aida Maddahi
    Division of Experimental Vascular Research, Department of Clinical Sciences, Lund University, Lund, Sweden
    J Cereb Blood Flow Metab 31:144-54. 2011
  7. doi request reprint Subarachnoid hemorrhage induces enhanced expression of thromboxane A2 receptors in rat cerebral arteries
    Saema Ansar
    Division of Experimental Vascular Research, Department of Clinical Sciences, Lund University, Sweden
    Brain Res 1316:163-72. 2010
  8. pmc Inhibition of cerebrovascular raf activation attenuates cerebral blood flow and prevents upregulation of contractile receptors after subarachnoid hemorrhage
    Saema Ansar
    Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, Lund, Sweden
    BMC Neurosci 12:107. 2011
  9. ncbi request reprint Cooperative effect of angiotensin AT(1) and endothelin ET(A) receptor antagonism limits the brain damage after ischemic stroke in rat
    Emelie Stenman
    Institution of Clinical Sciences Lund, Department of Experimental Vascular Research, Lund University, BMC A13, 22184 Lund, Sweden
    Eur J Pharmacol 570:142-8. 2007
  10. doi request reprint Enhanced expression of contractile endothelin ET(B) receptors in rat coronary artery after organ culture
    Evelina Johnsson
    Department of Clinical Sciences, Lund University, Lund, Sweden
    Eur J Pharmacol 582:94-101. 2008

Detail Information

Publications11

  1. pmc Regulation of enhanced cerebrovascular expression of proinflammatory mediators in experimental subarachnoid hemorrhage via the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathway
    Aida Maddahi
    Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, Lund, Sweden
    J Neuroinflammation 9:274. 2012
    ....
  2. pmc Enhanced expressions of microvascular smooth muscle receptors after focal cerebral ischemia occur via the MAPK MEK/ERK pathway
    Aida Maddahi
    Division of Experimental Vascular Research, BMC A13, Lund University, 221 84 Lund, Sweden
    BMC Neurosci 9:85. 2008
    ..Here we explored the role of the MEK/ERK pathway in receptor expression following ischemic brain injury using the specific MEK1 inhibitor U0126...
  3. pmc Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat
    Aida Maddahi
    Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, Lund, Sweden
    BMC Neurosci 10:56. 2009
    ..The formation of oedema and opening of the blood-brain barrier in stroke is associated with enhanced expression of metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1)...
  4. pmc The role of tumor necrosis factor-α and TNF-α receptors in cerebral arteries following cerebral ischemia in rat
    Aida Maddahi
    Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, Lund, Sweden
    J Neuroinflammation 8:107. 2011
    ..Secondly, we asked if the expression was regulated via activation of the MEK-ERK1/2 pathway...
  5. pmc Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway
    Aida Maddahi
    Department of Internal Medicine, Institute of Clinical Sciences, Lund University, Sweden
    J Neuroinflammation 7:14. 2010
    ....
  6. pmc Blockade of the MEK/ERK pathway with a raf inhibitor prevents activation of pro-inflammatory mediators in cerebral arteries and reduction in cerebral blood flow after subarachnoid hemorrhage in a rat model
    Aida Maddahi
    Division of Experimental Vascular Research, Department of Clinical Sciences, Lund University, Lund, Sweden
    J Cereb Blood Flow Metab 31:144-54. 2011
    ..These results suggested that inhibition of MEK/ERK signal transduction by a specific raf inhibitor administered up to 6 hours after SAH normalized the expression of pro-inflammatory mediators and extracellular matrix-related genes...
  7. doi request reprint Subarachnoid hemorrhage induces enhanced expression of thromboxane A2 receptors in rat cerebral arteries
    Saema Ansar
    Division of Experimental Vascular Research, Department of Clinical Sciences, Lund University, Sweden
    Brain Res 1316:163-72. 2010
    ..The results demonstrate that SAH results in CBF reduction and this is associated with the enhanced expression of TP receptors in the SMC of cerebral arteries and microvessels...
  8. pmc Inhibition of cerebrovascular raf activation attenuates cerebral blood flow and prevents upregulation of contractile receptors after subarachnoid hemorrhage
    Saema Ansar
    Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, Lund, Sweden
    BMC Neurosci 12:107. 2011
    ..The raf inhibitor will inhibit the molecular events upstream ERK1/2 and may provide a therapeutic window for treatment of cerebral ischemia after SAH...
  9. ncbi request reprint Cooperative effect of angiotensin AT(1) and endothelin ET(A) receptor antagonism limits the brain damage after ischemic stroke in rat
    Emelie Stenman
    Institution of Clinical Sciences Lund, Department of Experimental Vascular Research, Lund University, BMC A13, 22184 Lund, Sweden
    Eur J Pharmacol 570:142-8. 2007
    ..In conclusion, the present study shows that combined inhibition of angiotensin AT(1) and endothelin ET(A) receptors reduces the brain damage and improves the neurological outcome after ischemic stroke in rat...
  10. doi request reprint Enhanced expression of contractile endothelin ET(B) receptors in rat coronary artery after organ culture
    Evelina Johnsson
    Department of Clinical Sciences, Lund University, Lund, Sweden
    Eur J Pharmacol 582:94-101. 2008
    ..This is likely not related to endothelial dysfunction with putative loss of its vasodilator components, but rather explained by the up-regulation of contractile endothelin ET(B) receptors on smooth muscle cells...
  11. doi request reprint VIP/PACAP receptors in cerebral arteries of rat: characterization, localization and relation to intracellular calcium
    André Erdling
    Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, Lund, Sweden
    Neuropeptides 47:85-92. 2013
    ..The purpose of this study was to describe the effects of two putative VIP/PACAP receptor antagonists and the distribution of the receptor protein in rat brain vessels...