Martin Lauss

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. doi request reprint DNA methylation subgroups in melanoma are associated with proliferative and immunological processes
    Martin Lauss
    Department of Oncology and Pathology, Clinical Sciences, Lund University Hospital, Lund University, Lund, 221 85, Sweden
    BMC Med Genomics 8:73. 2015
  2. pmc Robust assignment of cancer subtypes from expression data using a uni-variate gene expression average as classifier
    Martin Lauss
    Department of Oncology, Clinical Sciences, Lund University and Lund University Hospital, Lund, Sweden
    BMC Cancer 10:532. 2010
  3. doi request reprint Genome methylation patterns in male breast cancer - Identification of an epitype with hypermethylation of polycomb target genes
    Ida Johansson
    Department of Oncology and Pathology, Clinical Sciences, and CREATE Health Strategic Center for Translational Cancer Research, Lund University, Lund, Sweden
    Mol Oncol 9:1565-79. 2015
  4. ncbi request reprint Molecular stratification of metastatic melanoma using gene expression profiling: Prediction of survival outcome and benefit from molecular targeted therapy
    Helena Cirenajwis
    Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Lund, Sweden
    Oncotarget 6:12297-309. 2015
  5. doi request reprint Genome-wide DNA methylation analysis of lung carcinoma reveals one neuroendocrine and four adenocarcinoma epitypes associated with patient outcome
    Anna Karlsson
    Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden
    Clin Cancer Res 20:6127-40. 2014
  6. pmc Molecular and genetic diversity in the metastatic process of melanoma
    Katja Harbst
    Department of Oncology, Clinical Sciences, Lund University, Sweden CREATE Health Strategic Centre for Clinical Cancer Research, Lund University, Sweden
    J Pathol 233:39-50. 2014
  7. doi request reprint Genomic and transcriptional alterations in lung adenocarcinoma in relation to smoking history
    Anna Karlsson
    Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden CREATE Health Strategic Center for Translational Cancer Research, Lund University, Lund, Sweden
    Clin Cancer Res 20:4912-24. 2014
  8. pmc Loss of CITED1, an MITF regulator, drives a phenotype switch in vitro and can predict clinical outcome in primary melanoma tumours
    Jillian Howlin
    Division of Oncology Pathology, Lund University Cancer Center Medicon Village, Scheelev gen, Lund, Sweden Cell and Experimental Pathology, Department of Laboratory Medicine Malm, Lund University, Sweden
    Peerj 3:e788. 2015
  9. pmc Genome-Wide DNA Methylation Analysis in Melanoma Reveals the Importance of CpG Methylation in MITF Regulation
    Martin Lauss
    1 Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Lund, Sweden 2 CREATE Health Strategic Center for Translational Cancer Research, Lund University, Lund, Sweden
    J Invest Dermatol 135:1820-8. 2015
  10. pmc Gene expression profiling of primary male breast cancers reveals two unique subgroups and identifies N-acetyltransferase-1 (NAT1) as a novel prognostic biomarker
    Ida Johansson
    Department of Oncology, Clinical Sciences, Lund University, Barngatan 2B, SE 22185 Lund, Sweden
    Breast Cancer Res 14:R31. 2012

Collaborators

Detail Information

Publications13

  1. doi request reprint DNA methylation subgroups in melanoma are associated with proliferative and immunological processes
    Martin Lauss
    Department of Oncology and Pathology, Clinical Sciences, Lund University Hospital, Lund University, Lund, 221 85, Sweden
    BMC Med Genomics 8:73. 2015
    ..DNA methylation at CpG dinucleotides is modified in tumorigenesis with potential impact on transcriptional activity...
  2. pmc Robust assignment of cancer subtypes from expression data using a uni-variate gene expression average as classifier
    Martin Lauss
    Department of Oncology, Clinical Sciences, Lund University and Lund University Hospital, Lund, Sweden
    BMC Cancer 10:532. 2010
    ..Here we present a new type of simple algorithm based on ROC analysis and the use of metagenes that we believe will be a good complement to existing algorithms...
  3. doi request reprint Genome methylation patterns in male breast cancer - Identification of an epitype with hypermethylation of polycomb target genes
    Ida Johansson
    Department of Oncology and Pathology, Clinical Sciences, and CREATE Health Strategic Center for Translational Cancer Research, Lund University, Lund, Sweden
    Mol Oncol 9:1565-79. 2015
    ..These findings further suggest that MBC is not readily defined using conventional criteria applied to FBC. ..
  4. ncbi request reprint Molecular stratification of metastatic melanoma using gene expression profiling: Prediction of survival outcome and benefit from molecular targeted therapy
    Helena Cirenajwis
    Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Lund, Sweden
    Oncotarget 6:12297-309. 2015
    ..02). In summary, the melanoma gene expression phenotypes are highly predictive of survival outcome and can further help to discriminate patients responding to targeted therapy. ..
  5. doi request reprint Genome-wide DNA methylation analysis of lung carcinoma reveals one neuroendocrine and four adenocarcinoma epitypes associated with patient outcome
    Anna Karlsson
    Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden
    Clin Cancer Res 20:6127-40. 2014
    ..However, whether clinically relevant subgroups based on DNA methylation patterns exist in lung cancer remains unclear...
  6. pmc Molecular and genetic diversity in the metastatic process of melanoma
    Katja Harbst
    Department of Oncology, Clinical Sciences, Lund University, Sweden CREATE Health Strategic Centre for Clinical Cancer Research, Lund University, Sweden
    J Pathol 233:39-50. 2014
    ....
  7. doi request reprint Genomic and transcriptional alterations in lung adenocarcinoma in relation to smoking history
    Anna Karlsson
    Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden CREATE Health Strategic Center for Translational Cancer Research, Lund University, Lund, Sweden
    Clin Cancer Res 20:4912-24. 2014
    ..Cigarette smoking is the major pathogenic factor for lung cancer. The precise mechanisms of tobacco-related carcinogenesis and its effect on the genomic and transcriptional landscape in lung cancer are not fully understood...
  8. pmc Loss of CITED1, an MITF regulator, drives a phenotype switch in vitro and can predict clinical outcome in primary melanoma tumours
    Jillian Howlin
    Division of Oncology Pathology, Lund University Cancer Center Medicon Village, Scheelev gen, Lund, Sweden Cell and Experimental Pathology, Department of Laboratory Medicine Malm, Lund University, Sweden
    Peerj 3:e788. 2015
    ..We hypothesize that CITED1 acts a regulator of MITF, functioning to maintain MITF levels in a range compatible with tumourigenesis...
  9. pmc Genome-Wide DNA Methylation Analysis in Melanoma Reveals the Importance of CpG Methylation in MITF Regulation
    Martin Lauss
    1 Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Lund, Sweden 2 CREATE Health Strategic Center for Translational Cancer Research, Lund University, Lund, Sweden
    J Invest Dermatol 135:1820-8. 2015
    ..The discovery that the activity of the master regulator of pigmentation, MITF, and its downstream targets may be regulated by hypermethylation has significant implications for understanding the development and evolvement of melanoma. ..
  10. pmc Gene expression profiling of primary male breast cancers reveals two unique subgroups and identifies N-acetyltransferase-1 (NAT1) as a novel prognostic biomarker
    Ida Johansson
    Department of Oncology, Clinical Sciences, Lund University, Barngatan 2B, SE 22185 Lund, Sweden
    Breast Cancer Res 14:R31. 2012
    ..The aim of the present study was to characterize MBC tumors transcriptionally, to classify them into comprehensive subgroups, and to compare them with female breast cancer (FBC)...
  11. pmc Molecular profiling reveals low- and high-grade forms of primary melanoma
    Katja Harbst
    Department of Oncology, Clinical Sciences, Lund University, Lund, Sweden
    Clin Cancer Res 18:4026-36. 2012
    ..This raises the possibility that a molecular structure exists even in the early stages of melanoma and that molecular determinants could underlie histophenotype and eventual patient outcome...
  12. pmc Efficient arsenic metabolism--the AS3MT haplotype is associated with DNA methylation and expression of multiple genes around AS3MT
    Karin S Engström
    Section of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden
    PLoS ONE 8:e53732. 2013
    ..This raises the possibility that several genes in this region are important for arsenic metabolism...