Bo A G Jonsson

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. doi Is acculturation associated with physical activity among female immigrants in Sweden?
    Lena S Jönsson
    Center for Primary Health Care Research, Department of Clinical Science, Lund University, Malmo SE 205 02, Sweden
    J Public Health (Oxf) 35:270-7. 2013
  2. ncbi Symptoms and immunologic markers among vulcanization workers in rubber industries in southern Sweden
    Lena S Jönsson
    Division of Occupational and Environmental Medicine, University Hospital, SE 221 85 Lund, Sweden
    Scand J Work Environ Health 33:272-9. 2007
  3. ncbi N-nitrosamines in the southern Swedish rubber industries - exposure, health effects, and immunologic markers
    Lena S Jönsson
    Division of Occupational and Environmental Medicine, Lund University Hospital, SE 221 85 Lund, Sweden
    Scand J Work Environ Health 35:203-11. 2009
  4. ncbi Levels of 2-thiothiazolidine-4-carboxylic acid (TTCA) and effect modification of polymorphisms of glutathione-related genes in vulcanization workers in the southern Sweden rubber industries
    Lena S Jönsson
    Division of Occupational and Environmental Medicine and Psychiatric Epidemiology, University Hospital, 221 85, Lund, Sweden
    Int Arch Occup Environ Health 80:589-98. 2007
  5. doi Gene expression in nasal lavage from hairdressers exposed to persulphate
    Lena S Jönsson
    Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University Hospital, Lund, Sweden
    Int Arch Occup Environ Health 82:1261-6. 2009
  6. doi Lung function in relation to 2-thiothiazolidine-4-carboxylic acid and genetic effect modification among rubber workers in Sweden
    Lena S Jönsson
    Department of Laboratory Medicine, Division of Occupational and Environmental Medicine, Lund University Hospital, SE 221 85 Lund, Sweden
    J Occup Environ Med 50:1006-12. 2008
  7. ncbi Influence of glutathione-related genes on symptoms and immunologic markers among vulcanization workers in the southern Sweden rubber industries
    Lena S Jönsson
    Division of Occupational and Environmental Medicine, University Hospital, 221 85, Lund, Sweden
    Int Arch Occup Environ Health 81:913-9. 2008
  8. doi Levels of 1-hydroxypyrene, symptoms and immunologic markers in vulcanization workers in the southern Sweden rubber industries
    Lena S Jönsson
    Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University Hospital, Lund, Sweden
    Int Arch Occup Environ Health 82:131-7. 2008
  9. ncbi Association between exposure to persistent organohalogen pollutants and epididymal and accessory sex gland function: multicentre study in Inuit and European populations
    Saad Elzanaty
    Scanian Andrology Centre, Fertility Centre, Malmo University Hospital, Lund University, Malmo, Sweden
    Reprod Toxicol 22:765-73. 2006
  10. doi Serum levels of perfluorinated compounds and sperm Y:X chromosome ratio in two European populations and in Inuit from Greenland
    Linus Kvist
    Department of Clinical Sciences, Molecular Genetic Reproductive Medicine, Lund University, Malmo, Sweden
    Reprod Toxicol 34:644-50. 2012

Collaborators

Detail Information

Publications59

  1. doi Is acculturation associated with physical activity among female immigrants in Sweden?
    Lena S Jönsson
    Center for Primary Health Care Research, Department of Clinical Science, Lund University, Malmo SE 205 02, Sweden
    J Public Health (Oxf) 35:270-7. 2013
    ..Immigrant women in Sweden have lower levels of leisure time physical activity (LTPA) than Swedish-born women. The reasons are unclear, although acculturation has been suggested to play a role...
  2. ncbi Symptoms and immunologic markers among vulcanization workers in rubber industries in southern Sweden
    Lena S Jönsson
    Division of Occupational and Environmental Medicine, University Hospital, SE 221 85 Lund, Sweden
    Scand J Work Environ Health 33:272-9. 2007
    ..Furthermore, the relation between exposure and these biomarkers of response was examined using urinary levels of 2-thiothiazolidine-4-carboxylic acid (TTCA), which reflect the exposure...
  3. ncbi N-nitrosamines in the southern Swedish rubber industries - exposure, health effects, and immunologic markers
    Lena S Jönsson
    Division of Occupational and Environmental Medicine, Lund University Hospital, SE 221 85 Lund, Sweden
    Scand J Work Environ Health 35:203-11. 2009
    ..The aim of this study was twofold: (i) to evaluate the air levels of N-nitrosamines in the Swedish rubber industry and (ii) to estimate the risk of symptoms and changed levels of immunologic markers in relation to these levels...
  4. ncbi Levels of 2-thiothiazolidine-4-carboxylic acid (TTCA) and effect modification of polymorphisms of glutathione-related genes in vulcanization workers in the southern Sweden rubber industries
    Lena S Jönsson
    Division of Occupational and Environmental Medicine and Psychiatric Epidemiology, University Hospital, 221 85, Lund, Sweden
    Int Arch Occup Environ Health 80:589-98. 2007
    ..The aim of the study was to determine TTCA levels and the modifying effects of glutathione-related genes in a group of Swedish rubber workers...
  5. doi Gene expression in nasal lavage from hairdressers exposed to persulphate
    Lena S Jönsson
    Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University Hospital, Lund, Sweden
    Int Arch Occup Environ Health 82:1261-6. 2009
    ..In this study, we analysed gene expression of cytokines in the nose in order to further investigate the mechanism for work-related bleaching powder-associated nasal symptoms...
  6. doi Lung function in relation to 2-thiothiazolidine-4-carboxylic acid and genetic effect modification among rubber workers in Sweden
    Lena S Jönsson
    Department of Laboratory Medicine, Division of Occupational and Environmental Medicine, Lund University Hospital, SE 221 85 Lund, Sweden
    J Occup Environ Med 50:1006-12. 2008
    ..What is the risk of impaired lung function in contemporary Swedish rubber workers and are there modifying effects of genetic variants?..
  7. ncbi Influence of glutathione-related genes on symptoms and immunologic markers among vulcanization workers in the southern Sweden rubber industries
    Lena S Jönsson
    Division of Occupational and Environmental Medicine, University Hospital, 221 85, Lund, Sweden
    Int Arch Occup Environ Health 81:913-9. 2008
    ..Polymorphisms in genes, which are involved in the defense against reactive oxygen species and metabolism of toxic substances present in the vulcanization fumes, were analyzed...
  8. doi Levels of 1-hydroxypyrene, symptoms and immunologic markers in vulcanization workers in the southern Sweden rubber industries
    Lena S Jönsson
    Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University Hospital, Lund, Sweden
    Int Arch Occup Environ Health 82:131-7. 2008
    ..The risk of symptoms and changed levels of immunologic markers were investigated in relation to the 1-HP levels...
  9. ncbi Association between exposure to persistent organohalogen pollutants and epididymal and accessory sex gland function: multicentre study in Inuit and European populations
    Saad Elzanaty
    Scanian Andrology Centre, Fertility Centre, Malmo University Hospital, Lund University, Malmo, Sweden
    Reprod Toxicol 22:765-73. 2006
    ..In conclusion, the negative effects of POP on sperm motility, observed in the same study population might partly be caused by post-testicular mechanisms, involving a decreased epididymal function...
  10. doi Serum levels of perfluorinated compounds and sperm Y:X chromosome ratio in two European populations and in Inuit from Greenland
    Linus Kvist
    Department of Clinical Sciences, Molecular Genetic Reproductive Medicine, Lund University, Malmo, Sweden
    Reprod Toxicol 34:644-50. 2012
    ..002, p=0.044). In conclusion, there was a negative trend between Y:X ratio and PFOS in the Inuit, while there was no association between PFOA and the Y:X ratio in adult men...
  11. ncbi Androgen receptor gene CAG repeat length as a modifier of the association between persistent organohalogen pollutant exposure markers and semen characteristics
    Aleksander Giwercman
    Molecular Reproductive Medicine Research Unit, Department of Clinical Sciences, Reproductive Medicine Centre, Malmo University Hospital, Lund University, Malmo, Sweden
    Pharmacogenet Genomics 17:391-401. 2007
    ..We aimed to investigate whether the CAG and GGN polymorphisms in the androgen receptor gene modify the effect of persistent organohalogen pollutant exposure on human sperm characteristics...
  12. ncbi Exposure-response relationships for hexahydrophthalic and methylhexahydrophthalic anhydrides with total plasma protein adducts as biomarkers
    Seema Rosqvist
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, Lund, Sweden
    Scand J Work Environ Health 29:297-303. 2003
    ....
  13. doi Time-dependent proteomic iTRAQ analysis of nasal lavage of hairdressers challenged by persulfate
    Monica H Kåredal
    Department of Laboratory Medicine, Lund University, SE 221 85 Lund, Sweden
    J Proteome Res 9:5620-8. 2010
    ..Our results suggest there may be differences between the mechanisms responsible for the rhinitis in the symptomatic and atopic group...
  14. doi Blood serum concentrations of perfluorinated compounds in men from Greenlandic Inuit and European populations
    Christian H Lindh
    Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 221 85 Lund, Sweden
    Chemosphere 88:1269-75. 2012
    ..For the other populations no strong determinants were found...
  15. doi Strategy for identification and detection of multiple oxidative modifications within proteins applied on persulfate-oxidized hemoglobin and human serum albumin
    Harriet Mortstedt
    Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund, Lund University, SE 221 85 Lund, Sweden
    Rapid Commun Mass Spectrom 25:327-40. 2011
    ..For peptides containing oxidized tryptophan the oxidation degree increased after exposure. Some of these oxidized peptides may be suitable as biomarkers; however, further evaluation is required...
  16. doi Determinants of maternal and fetal exposure and temporal trends of perfluorinated compounds
    Amanda Ode
    Division of Occupational and Environmental Medicine, Lund University, 221 85, Lund, Sweden
    Environ Sci Pollut Res Int 20:7970-8. 2013
    ..Our results demonstrate that maternal country of origin, parity, and gestational age might be associated with PFC exposure...
  17. pmc Impact of PCB and p,p'-DDE contaminants on human sperm Y:X chromosome ratio: studies in three European populations and the Inuit population in Greenland
    Tarmo Tiido
    Molecular Reproductive Medicine Research Unit, Department of Clinical Sciences, Fertility Centre, Malmo University Hospital, Lund University, Malmo, Sweden
    Environ Health Perspect 114:718-24. 2006
    ..Our aim in the present study was to investigate whether exposure to 2,2 ,4,4 ,5,5 -hexachlorobiphenyl (PCB-153) and dichlorodiphenyldichloroethene (p,p -DDE) affects sperm Y:X chromosome distribution...
  18. ncbi Determination of isocyanates in air using 1-(2-methoxyphenyl)piperazine-impregnated filters: long-term sampling performance and field comparison with impingers with dibutylamine
    Carl J Sennbro
    Department of Occupational and Environmental Medicine, University Hospital, SE 221 85 Lund, Sweden
    Ann Occup Hyg 48:415-24. 2004
    ..For long-term monitoring the 2MP method can be applied for TDI but, since the method underestimates the concentrations, a correction factor is needed which needs to be corroborated further...
  19. ncbi A survey of airborne isocyanate exposure in 13 Swedish polyurethane industries
    Carl J Sennbro
    Department of Occupational and Environmental Medicine, University Hospital, SE 221 85 Lund, Sweden
    Ann Occup Hyg 48:405-14. 2004
    ..Isocyanic acid, which could not be sampled by the 2MP method used for personal monitoring, was found by short-term stationary monitoring in levels up to 38 p.p.b. in the flame lamination plants...
  20. doi Methylhexahydrophthalic anhydride adducted albumin tryptic peptides in nasal lavage fluid
    Marina C Jeppsson
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, Lund, Sweden
    Inhal Toxicol 21:1013-20. 2009
    ..The results also show a correlation between adducted peptides and albumin in nasal lavage. Furthermore, there may be a difference in the potential to induce hyperresponsiveness between adducts bound to different amino acids...
  21. ncbi Correlations between air levels of hexahydrophthalic anhydride (HHPA) and HHPA-adducted albumin tryptic peptides in nasal lavage fluid from experimentally exposed volunteers
    Monica H Kristiansson
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, SE 221 85 Lund, Sweden
    Rapid Commun Mass Spectrom 18:1592-8. 2004
    ..It was possible to detect exposures below 10 microg/m3 with the method. Thus, these adducted peptides may be used as biomarkers of exposure, which may better estimate the risk than previous biomarkers developed for OAAs...
  22. pmc Fetal exposure to perfluorinated compounds and attention deficit hyperactivity disorder in childhood
    Amanda Ode
    Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden
    PLoS ONE 9:e95891. 2014
    ..The association between exposure to perfluorinated compounds (PFCs) and attention deficit hyperactivity disorder (ADHD) diagnosis has been sparsely investigated in humans and the findings are inconsistent...
  23. doi Very high correlations between fresh weight and lipid-adjusted PCB-153 serum concentrations: irrespective of fasting status, age, body mass index, gender, or exposure distributions
    Lars Rylander
    Division of Occupational and Environmental Medicine, Lund University, SE 221 85 Lund, Sweden
    Chemosphere 88:828-31. 2012
    ..This raises the question of the necessity of lipid adjustment. The aim of the present study was to evaluate the correlation between fresh weight and lipid adjusted concentrations...
  24. doi Screening method using selected reaction monitoring for targeted proteomics studies of nasal lavage fluid
    Harriet Mortstedt
    Department of Laboratory Medicine, Lund, Division of Occupational and Environmental Medicine, Lund University, SE 221 85 Lund, Sweden
    J Proteome Res 12:234-47. 2013
    ..In conclusion, a high throughput screening method for relative quantification of 244 NLF proteins was developed. The method should be of general use in any proteomic study of the upper airways...
  25. ncbi Biological monitoring of exposure to toluene diisocyanate
    Carl Johan Sennbro
    Department of Occupational and Environmental Medicine, University Hospital, Lund, Sweden
    Scand J Work Environ Health 30:371-8. 2004
    ..In this study, 2,4- and 2,6-toluenediamine in hydrolyzed urine and plasma were evaluated as biomarkers of exposure to 2,4- and 2,6-TDI, respectively...
  26. ncbi Rapid decline of persistent organochlorine pollutants in serum among young Swedish males
    Anna Axmon
    Division of Occupational and Environmental Medicine and Psychiatric Epidemiology, Department of Laboratory Medicine, Lund University Hospital, SE 221 85 Lund, Sweden
    Chemosphere 70:1620-8. 2008
    ..The analogous analysis was not done for p,p'-DDE since the median serum concentration in 2004 was below the LOD...
  27. doi Identification of covalent binding sites of phthalic anhydride in human hemoglobin
    Marina C Jeppsson
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, SE 221 85 Lund, Sweden
    Chem Res Toxicol 21:2156-63. 2008
    ..It was also found that PA differs in its binding site as compared to hexahydrophthalic anhydride. The result of this study suggests several interesting applications of biological monitoring...
  28. ncbi Acid sphingomyelinase is induced by butyrate but does not initiate the anticancer effect of butyrate in HT29 and HepG2 cells
    Jun Wu
    Gastroenterology Laboratory, Biomedical Center B11, Lund University, S 221 84 Lund, Sweden
    J Lipid Res 46:1944-52. 2005
    ..In conclusion, butyrate regulates SM metabolism by stimulating acid SMase expression in colon and liver cancer cells, but the increased acid SMase is not a critical mechanism for initiating the anticancer effects of butyrate...
  29. pmc Inter-population variations in concentrations, determinants of and correlations between 2,2',4,4',5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p'-DDE): a cross-sectional study of 3161 men and women from Inuit and
    Bo A G Jonsson
    Department of Occupational and Environmental Medicine, Lund University Hospital, SE 221 85 Lund, Sweden
    Environ Health 4:27. 2005
    ....
  30. pmc A nested case-control study of intrauterine exposure to persistent organochlorine pollutants in relation to risk of type 1 diabetes
    Anna Rignell-Hydbom
    Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden
    PLoS ONE 5:e11281. 2010
    ..The aim of this case-control study was to assess possible impacts of in utero exposure to POPs on type 1 diabetes...
  31. doi Analysis of ethylenethiourea as a biomarker in human urine using liquid chromatography/triple quadrupole mass spectrometry
    Christian H Lindh
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, SE 221 85 Lund, Sweden
    Rapid Commun Mass Spectrom 22:2573-9. 2008
    ..5% ETU. Two healthy volunteers received 8.9 microg/kg body weight (b.w.) Ridomil Gold in a single oral dose followed by urine sampling for 104 h post-exposure. The elimination half-life of ETU was estimated to 17-23 h...
  32. doi Identification of covalent binding sites of ethyl 2-cyanoacrylate, methyl methacrylate and 2-hydroxyethyl methacrylate in human hemoglobin using LC/MS/MS techniques
    Marina C Jeppsson
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, SE 221 85 Lund, Sweden
    J Chromatogr B Analyt Technol Biomed Life Sci 878:2474-82. 2010
    ..The adducted peptides were possible to measure using LC/MS/MS in selected reaction monitoring mode. These peptides may be used for biological monitoring of exposure to ECA, MMA and HEMA...
  33. doi N-nitrosamines are associated with shorter telomere length
    Huiqi Li
    Section of Occupational and Environmental Medicine, Lund University Hospital, SE 221 85 Lund, Sweden
    Scand J Work Environ Health 37:316-24. 2011
    ..Aiming to examine the relationship between DNA-damaging agents and average telomere length in peripheral blood, we conducted a cross-sectional study among 157 workers working in the rubber industry in Sweden...
  34. doi Analysis of chlormequat in human urine as a biomarker of exposure using liquid chromatography triple quadrupole mass spectrometry
    Christian H Lindh
    Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden
    J Chromatogr B Analyt Technol Biomed Life Sci 879:1551-6. 2011
    ..The levels found in the population samples are several magnitudes lower than those found in the experimental exposure, which corresponds to an oral exposure of 50% of the ADI for CCC...
  35. ncbi Evaluation of an immunoaffinity extraction column for enrichment of adducts between human serum albumin and hexahydrophthalic anhydride in plasma
    Gunvor A Johannesson
    Department of Laboratory Medicine, Lund University Hospital, SE 221 85 Lund, Sweden
    Biomed Chromatogr 22:327-32. 2008
    ..15-1.2 nmol conjugate. The evaluation showed that the IAE column had adequate affinity towards the HHPA adducts and that the adducts could be extracted with good recovery and precision from a large volume of plasma...
  36. ncbi Evaluation of exposure biomarkers from percutaneous absorption of N-methyl-2-pyrrolidone
    Bengt Akesson
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, Lund University Hospital, S 221 85 Lund, Sweden
    Scand J Work Environ Health 30:306-12. 2004
    ..For this purpose, differences in toxicokinetics between men and women and between pure and water-mixed NMP were evaluated after dermal absorption...
  37. ncbi Analysis of phenoxyacetic acid herbicides as biomarkers in human urine using liquid chromatography/triple quadrupole mass spectrometry
    Christian H Lindh
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, Lund, Sweden
    Rapid Commun Mass Spectrom 22:143-50. 2008
    ..After exposure, between 90 and 101% of the dose was recovered in the urine. In the female subject, 23%, and in the male subject 17%, of MCPA was excreted as HMCPA...
  38. ncbi Upper reference limits for biomarkers of exposure to aromatic diisocyanates
    Carl Johan Sennbro
    Department of Occupational and Environmental Medicine, University Hospital, 221 85 Lund, Sweden
    Int Arch Occup Environ Health 78:541-6. 2005
    ..These analytes are biomarkers of exposure to 2,4-toluene diisocyanate and 2,6-toluene diisocyanate (2,4-TDI and 2,6-TDI), 1,5-naphtalene diisocyanate (NDI) and 4,4'-methylenediphenyl diisocyanate (MDI), respectively...
  39. ncbi Analysis of 3,5-dichloroaniline as a biomarker of vinclozolin and iprodione in human urine using liquid chromatography/triple quadrupole mass spectrometry
    Christian H Lindh
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, SE 221 85 Lund, Sweden
    Rapid Commun Mass Spectrom 21:536-42. 2007
    ..Two healthy volunteers received 200 microg single oral doses of each pesticide followed by urine sampling during 72-120 h post-exposure. Between 78-107% of the dose was recovered as 3,5-DCA in the urine after exposure...
  40. ncbi Validation of urinary excretion of cyclophosphamide as a biomarker of exposure by studying its renal clearance at high and low plasma concentrations in cancer patients
    Maria Hedmer
    Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University Hospital, 221 85 Lund, Sweden
    Int Arch Occup Environ Health 81:285-93. 2008
    ..The aim of this study was to investigate if the proportion of the CP dose that is excreted in urine (renal clearance) is constant over different plasma drug concentrations and other pharmacokinetic parameters, e.g., urine flow...
  41. doi High-throughput method for the analysis of ethylenethiourea with direct injection of hydrolysed urine using online on-column extraction liquid chromatography and triple quadrupole mass spectrometry
    Eva Ekman
    Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Faculty of Medicine, Lund University, SE 221 85 Lund, Sweden
    J Chromatogr B Analyt Technol Biomed Life Sci 934:53-9. 2013
    ..The results show an estimated half-life of ETU between 34 and 72h. Although the experiment is limited to two individuals, the data provide valuable and new information regarding the toxicokinetics of ETU after dermal exposure. ..
  42. pmc Monoacylglycerols activate TRPV1--a link between phospholipase C and TRPV1
    Peter M Zygmunt
    Department of Laboratory Medicine, Lund University, Lund, Sweden Lund University Pain Research Centre, Lund University, Lund, Sweden
    PLoS ONE 8:e81618. 2013
    ....
  43. ncbi Human meconium contains significant amounts of alkaline sphingomyelinase, neutral ceramidase, and sphingolipid metabolites
    Rui Dong Duan
    Department of Clinical Sciences, Medicine Gastroenterology and Nutrition, Lund University Hospital, Lund, Sweden
    Pediatr Res 61:61-6. 2007
    ..In conclusion, Alk-SMase and ceramidase are expressed in the gut of both preterm and term newborn infants and may generate bioactive sphingolipid messengers...
  44. ncbi Urinary phthalate metabolites and biomarkers of reproductive function in young men
    Bo A G Jonsson
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, Lund University Hospital, Lund, Sweden
    Epidemiology 16:487-93. 2005
    ..A recent study in humans reported dose-response relations between low phthalate levels in urine and human semen parameters, which raises the question whether humans are more sensitive to phthalate exposure than animals...
  45. ncbi Biomarkers of exposure in Monday morning urine samples as a long-term measure of exposure to aromatic diisocyanates
    Håkan Tinnerberg
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, Lund University, S 221 85, Lund, Sweden
    Int Arch Occup Environ Health 87:365-72. 2014
    ....
  46. pmc Effects of diesel exposure on lung function and inflammation biomarkers from airway and peripheral blood of healthy volunteers in a chamber study
    Yiyi Xu
    Division of Occupational and Environmental Medicine, Lund University, SE 221 85 Lund, Sweden
    Part Fibre Toxicol 10:60. 2013
    ..We prolonged the exposure period and investigated how quickly diesel exhaust can induce respiratory and systemic effects...
  47. pmc Vascular effects of anandamide and N-acylvanillylamines in the human forearm and skin microcirculation
    Pouya Movahed
    Department of Clinical and Experimental Pharmacology, Lund University Hospital, SE 221 85 Lund, Sweden
    Br J Pharmacol 146:171-9. 2005
    ..The results are consistent with this lipid being an activator of TRPV1 on primary sensory nerves, but do not support a role for anandamide as a circulating vasoactive hormone in the human forearm vascular bed...
  48. pmc A nested case-control study of intrauterine exposure to persistent organochlorine pollutants and the risk of hypospadias
    Anna Rignell-Hydbom
    Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden
    PLoS ONE 7:e44767. 2012
    ..The aim of this case-control study was to investigate the association between fetal exposure to persistent organochlorine pollutants (POP) and the risk for hypospadias...
  49. ncbi Development and validation of methods for environmental monitoring of cyclophosphamide in workplaces
    Maria Hedmer
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, SE 221 85 Lund, Sweden
    J Environ Monit 6:979-84. 2004
    ..The developed methods were applied to the measurement of contamination with CP in a hospital pharmacy. Trace amounts of CP, 1.3 and 1.4 ng, were detected on surfaces in the pharmacy...
  50. ncbi In vivo conjugation of nasal lavage proteins by hexahydrophthalic anhydride
    Gunvor Johannesson
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, Lund University Hospital, SE 221 85, Lund, Sweden
    Toxicol Appl Pharmacol 194:69-78. 2004
    ..Hypotheses for development of airways diseases by adduction of this allergenic compound to the NLF proteins in humans were established...
  51. ncbi Development, validation and characterization of an analytical method for the quantification of hydrolysable urinary metabolites and plasma protein adducts of 2,4- and 2,6-toluene diisocyanate, 1,5-naphthalene diisocyanate and 4,4'-methylenediphenyl diisoc
    Carl Johan Sennbro
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, Lund, Sweden
    Biomarkers 8:204-17. 2003
    ..74-0.90. The methods presented here will be valuable for the development of biological monitoring methods for diisocyanates...
  52. doi Time trends between 1987 and 2007 for perfluoroalkyl acids in plasma from Swedish women
    Anna Axmon
    Department of Occupational and Environmental Medicine, Lund University, SE 221 85 Lund, Sweden Electronic address
    Chemosphere 102:61-7. 2014
    ..73 ng mL(-1), 0.28 ng mL(-1), and 0.24 ng mL(-1), respectively, during the last study period...
  53. ncbi Levels of N-methyl-2-pyrrolidone (NMP) and its metabolites in plasma and urine from volunteers after experimental exposure to NMP in dry and humid air
    Martin A Carnerup
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, Lund University Hospital, S 221 85 Lund, Sweden
    Toxicol Lett 162:139-45. 2006
    ..In addition, 2-P was confirmed to be an NMP metabolite in humans. This may be of importance for the developmental toxicity of NMP since 2-P have been described to be a reproductively toxic substance...
  54. ncbi Determination of hexahydrophthalic anhydride adducts to human serum albumin
    Monica H Kristiansson
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, SE 221 85 Lund, Sweden
    Biomarkers 8:343-59. 2003
    ..This knowledge generates the possibility of developing methods for the biological monitoring of HHPA exposure by analysing tryptic peptides including these binding sites...
  55. pmc Human biological monitoring of suspected endocrine-disrupting compounds
    Moosa Faniband
    Department of Laboratory Medicine, Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden
    Asian J Androl 16:5-16. 2014
    ..The aspects discussed are origin to exposure, metabolism, matrices to analyse, analytical determination methods, determinants, and time trends...
  56. ncbi Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system
    Edward D Hogestatt
    Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, SE 221 85 Lund, Sweden
    J Biol Chem 280:31405-12. 2005
    ....
  57. pmc Intestinal alkaline sphingomyelinase hydrolyses and inactivates platelet-activating factor by a phospholipase C activity
    Jun Wu
    Gastroenterology Laboratory, Biomedical Centre, B11, Lund University, S 221 84 Lund, Sweden
    Biochem J 394:299-308. 2006
    ..In conclusion, alk-SMase hydrolyses and inactivates PAF by a phospholipase C activity. The finding reveals a novel function, by which alk-SMase may counteract the development of intestinal inflammation and colon cancer...
  58. ncbi Mass spectrometric characterization of human hemoglobin adducts formed in vitro by hexahydrophthalic anhydride
    Monica H Kristiansson
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, SE 221 85 Lund, Sweden
    Chem Res Toxicol 15:562-9. 2002
    ..These results will constitute a basis for studies on structure-activity relationships as well as for development of methods for biological monitoring of acid anhydrides...
  59. ncbi Determination of cortisol in human saliva using liquid chromatography-electrospray tandem mass spectrometry
    Bo A G Jonsson
    Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, University Hospital, S 221 85, Lund, Sweden
    J Chromatogr B Analyt Technol Biomed Life Sci 784:63-8. 2003
    ..In addition, the method was compared to analysis by an immunological method. The values from the immunological method were 2.7 times higher than the LC-MS-MS results...