Richard Ingemansson

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. doi A protective device for negative-pressure therapy in patients with mediastinitis
    Richard Ingemansson
    Department of Cardiothoracic Surgery, Skane University Hospital, Lund University, Lund, Sweden
    Ann Thorac Surg 95:362-4. 2013
  2. pmc Up-regulation of endothelin type B receptors in the human internal mammary artery in culture is dependent on protein kinase C and mitogen-activated kinase signaling pathways
    David Nilsson
    Department of Medicine, Lund University Hospital, Sweden
    BMC Cardiovasc Disord 8:21. 2008
  3. doi Comparative outcome of double lung transplantation using conventional donor lungs and non-acceptable donor lungs reconditioned ex vivo
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Heart and Lung Centre, Lund University Hospital, SE 221 85 Lund, Sweden
    Interact Cardiovasc Thorac Surg 12:162-5. 2011
  4. ncbi PKC and MAPK signalling pathways regulate vascular endothelin receptor expression
    David Nilsson
    Department of Medicine, Lund University Hospital, Lund, Sweden
    Eur J Pharmacol 580:190-200. 2008
  5. doi Pressure transduction to the thoracic cavity during topical negative pressure therapy of a sternotomy wound
    Christian Torbrand
    Department of Medicine, Lund University Hospital, Lund, Sweden
    Int Wound J 5:579-84. 2008
  6. ncbi Changes in cardiac pumping efficiency and intra-thoracic organ volume during negative pressure wound therapy of sternotomy wounds, assessment using magnetic resonance imaging
    Christian Torbrand
    Department of Ophthalmology, Lund University Hospital, Lund, Sweden
    Int Wound J 7:115-21. 2010
  7. doi Topical negative pressure effects on coronary blood flow in a sternal wound model
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Heart and Lung Center, Lund University Hospital, Lund, Sweden
    Int Wound J 5:503-9. 2008
  8. doi Haemodynamic effects of -75 mmHg negative pressure therapy in a porcine sternotomy wound model
    Arash Mokhtari
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Int Wound J 6:48-54. 2009
  9. doi Clinical transplantation of initially rejected donor lungs after reconditioning ex vivo
    Richard Ingemansson
    Department of Cardiothoracic Surgery, Heart Lung Division, Lund University Hospital, Lund, Sweden
    Ann Thorac Surg 87:255-60. 2009
  10. doi Topical negative pressure therapy of a sternotomy wound increases sternal fluid content but does not affect internal thoracic artery blood flow: assessment using magnetic resonance imaging
    Rainer Petzina
    Department of Medicine, Lund University Hospital, Lund, Sweden
    J Thorac Cardiovasc Surg 135:1007-13. 2008

Detail Information

Publications60

  1. doi A protective device for negative-pressure therapy in patients with mediastinitis
    Richard Ingemansson
    Department of Cardiothoracic Surgery, Skane University Hospital, Lund University, Lund, Sweden
    Ann Thorac Surg 95:362-4. 2013
    ..The median duration of NPWT was 8 days (range, 6-14 days). No major bleeding or signs of organ damage were observed. The use of a protective device seems to decrease the risk of bleeding complications...
  2. pmc Up-regulation of endothelin type B receptors in the human internal mammary artery in culture is dependent on protein kinase C and mitogen-activated kinase signaling pathways
    David Nilsson
    Department of Medicine, Lund University Hospital, Sweden
    BMC Cardiovasc Disord 8:21. 2008
    ..We hypothesize that mitogen-activated kinases (MAPK) and protein kinase C (PKC) are involved in the regulation of endothelin ETB receptors in human internal mammary arteries...
  3. doi Comparative outcome of double lung transplantation using conventional donor lungs and non-acceptable donor lungs reconditioned ex vivo
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Heart and Lung Centre, Lund University Hospital, SE 221 85 Lund, Sweden
    Interact Cardiovasc Thorac Surg 12:162-5. 2011
    ..Ex vivo lung evaluation and reconditioning might not prolong early postoperative course in double lung transplantation. However, given the small number of patients, there might be a failure to detect a difference between the two groups...
  4. ncbi PKC and MAPK signalling pathways regulate vascular endothelin receptor expression
    David Nilsson
    Department of Medicine, Lund University Hospital, Lund, Sweden
    Eur J Pharmacol 580:190-200. 2008
    ..Inhibiting these intracellular signal transduction pathways may provide a future therapeutic target for hindering the development of vascular endothelin receptor changes in cardiovascular disease...
  5. doi Pressure transduction to the thoracic cavity during topical negative pressure therapy of a sternotomy wound
    Christian Torbrand
    Department of Medicine, Lund University Hospital, Lund, Sweden
    Int Wound J 5:579-84. 2008
    ....
  6. ncbi Changes in cardiac pumping efficiency and intra-thoracic organ volume during negative pressure wound therapy of sternotomy wounds, assessment using magnetic resonance imaging
    Christian Torbrand
    Department of Ophthalmology, Lund University Hospital, Lund, Sweden
    Int Wound J 7:115-21. 2010
    ..Cardiac pumping efficiency returns to pre-sternotomy levels during NPWT. This may contribute to the clinical benefits of NPWT over open-chest care, including the stabilizing effects and the reduced need for mechanical ventilation...
  7. doi Topical negative pressure effects on coronary blood flow in a sternal wound model
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Heart and Lung Center, Lund University Hospital, Lund, Sweden
    Int Wound J 5:503-9. 2008
    ..4 ml/minute before to 183.2 +/- 18.9 ml/minute after TNP application, P < 0.05. TNP of -50 mmHg applied over the LAD region induced a significant increase in the total coronary blood flow in both normal and ischaemic myocardium...
  8. doi Haemodynamic effects of -75 mmHg negative pressure therapy in a porcine sternotomy wound model
    Arash Mokhtari
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Int Wound J 6:48-54. 2009
    ..The present study shows that, with a suitable foam application technique, -75 mmHg can be applied without compromising the central haemodynamics...
  9. doi Clinical transplantation of initially rejected donor lungs after reconditioning ex vivo
    Richard Ingemansson
    Department of Cardiothoracic Surgery, Heart Lung Division, Lund University Hospital, Lund, Sweden
    Ann Thorac Surg 87:255-60. 2009
    ..Only about 20% of donor lungs are accepted for transplantation. A method to evaluate and recondition lungs ex vivo has been tested on donor lungs that have been rejected for transplantation...
  10. doi Topical negative pressure therapy of a sternotomy wound increases sternal fluid content but does not affect internal thoracic artery blood flow: assessment using magnetic resonance imaging
    Rainer Petzina
    Department of Medicine, Lund University Hospital, Lund, Sweden
    J Thorac Cardiovasc Surg 135:1007-13. 2008
    ..No study has yet been performed to examine the effect of topical negative pressure on the blood and fluid content in the sternal bone marrow, which is a crucial component in osteitis...
  11. doi Preventing heart injury during negative pressure wound therapy in cardiac surgery: assessment using real-time magnetic resonance imaging
    Malin Malmsjo
    Department of Medicine, Lund University Hospital, Lund, Sweden
    J Thorac Cardiovasc Surg 138:712-7. 2009
    ..The present study aimed to examine the effects of negative pressure wound therapy on the position of the heart in relation to the thoracic wall using magnetic resonance imaging in a porcine sternotomy wound model...
  12. doi Changes in cardiac pumping efficiency and intra-thoracic organ volume during negative pressure wound therapy of sternotomy wounds, assessment using magnetic resonance imaging
    Christian Torbrand
    Department of Ophthalmology, Lund University Hospital, Lund, Sweden
    Int Wound J 7:305-11. 2010
    ..Cardiac pumping efficiency returns to pre-sternotomy levels during NPWT. This may contribute to the clinical benefits of NPWT over open-chest care, including the stabilizing effects and the reduced need for mechanical ventilation...
  13. doi The use of a rigid disc to protect exposed structures in wounds treated with negative pressure wound therapy: effects on wound bed pressure and microvascular blood flow
    Erik Anesäter
    Department of Ophthalmology, Lund University and Skåne University Hospital, Lund, Sweden
    Wound Repair Regen 20:611-6. 2012
    ..The insertion of a rigid barrier counteracts this effect. The placement of a rigid disc over exposed blood vessels or nerves may protect these structures from rupture and damage...
  14. doi The influence on wound contraction and fluid evacuation of a rigid disc inserted to protect exposed organs during negative pressure wound therapy
    Erik Anesäter
    Department of Ophthalmology, Lund University and Skåne University Hospital, Lund, Sweden
    Int Wound J 8:393-9. 2011
    ..This study shows that a rigid barrier may be placed under the wound filler to protect exposed structures during NPWT without affecting wound contraction and fluid removal, which are two crucial features of NPWT...
  15. doi Impact of different topical negative pressure levels on myocardial microvascular blood flow
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Cardiovasc Revasc Med 9:29-35. 2008
    ..The present study was designed to elucidate the effect of different TNP levels between -50 and -150 mmHg on microvascular flow in normal and ischemic myocardium...
  16. doi A rigid disc for protection of exposed blood vessels during negative pressure wound therapy
    Erik Anesäter
    Lund University and Skåne University Hospital, Lund, Sweden
    Surg Innov 20:74-80. 2013
    ..Inserting a rigid disc in the wound may protect these structures. The authors examined the effects of rigid discs on wound bed tissue pressure and blood flow through a large blood vessel in the wound bed during NPWT...
  17. pmc A compare between myocardial topical negative pressure levels of -25 mmHg and -50 mmHg in a porcine model
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    BMC Cardiovasc Disord 8:14. 2008
    ..The present study was designed to elucidate the difference between -25 mmHg and -50 mmHg TNP on microvascular flow in normal and ischemic myocardium...
  18. doi Micro- and macromechanical effects on the wound bed of negative pressure wound therapy using gauze and foam
    Ola Borgquist
    Department of Ophthalmology, Lund University Hospital, Lund, Sweden
    Ann Plast Surg 64:789-93. 2010
    ..The degrees of micro- and macrodeformation of the wound bed are similar after NPWT regardless if foam or gauze is used as wound filler...
  19. doi The cost of vacuum-assisted closure therapy in treatment of deep sternal wound infection
    Arash Mokhtari
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Scand Cardiovasc J 42:85-9. 2008
    ..8 times that for normal, CABG surgery. Promising results have been reported with vacuum-assisted closure (VAC) therapy in patients with DSWI. This study presents the cost of VAC therapy in patients with DSWI after CABG surgery...
  20. ncbi Comparison of bacteria and fungus-binding mesh, foam and gauze as fillers in negative pressure wound therapy--pressure transduction, wound edge contraction, microvascular blood flow and fluid retention
    Malin Malmsjo
    Department of Ophthalmology, Lund University, Lund, Sweden Department of Cardiothoracic Surgery, Lund University, Lund, Sweden
    Int Wound J 10:597-605. 2013
    ..This, in combination with its pathogen-binding properties, makes this mesh an interesting wound filler for use in NPWT...
  21. pmc Wound contraction and macro-deformation during negative pressure therapy of sternotomy wounds
    Christian Torbrand
    Department of Ophthalmology, Lund University and Skåne University Hospital, Lund, Sweden
    J Cardiothorac Surg 5:75. 2010
    ..However, only few studies have been performed to evaluate this hypothesis. The present study was performed to investigate the effects of NPWT on wound contraction and wound edge tissue deformation...
  22. pmc No hypoperfusion is produced in the epicardium during application of myocardial topical negative pressure in a porcine model
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    J Cardiothorac Surg 2:53. 2007
    ..The current study was designed to elucidate whether hypoperfusion was produced during myocardial TNP...
  23. doi Wound edge microvascular blood flow during negative-pressure wound therapy: examining the effects of pressures from -10 to -175 mmHg
    Ola Borgquist
    Department of Ophthalmology and Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Plast Reconstr Surg 125:502-9. 2010
    ..However, this pressure may cause pain and ischemia and often has to be reduced. The aim of the present study was to examine the blood flow effects of different levels of negative pressures (-10 to -175 mmHg)...
  24. doi Wound edge microvascular blood flow: effects of negative pressure wound therapy using gauze or polyurethane foam
    Malin Malmsjo
    Department of Ophthalmology, Lund University Hospital, Lund, Sweden
    Ann Plast Surg 63:676-81. 2009
    ..Altered microvascular blood flow to the wound edge may be one of the mechanisms by which NPWT facilitates healing...
  25. doi Effects of green foam, black foam and gauze on contraction, blood flow and pressure delivery to the wound bed in negative pressure wound therapy
    Malin Malmsjo
    Department of Ophthalmology, Lund University and Skåne University Hospital, Lund, Sweden
    J Plast Reconstr Aesthet Surg 64:e289-96. 2011
    ..The aim of the present study was to examine these biological effects in the wound edge using different types of wound fillers...
  26. doi Myocardial topical negative pressure increases blood flow in hypothermic, ischemic myocardium
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Scand Cardiovasc J 42:345-53. 2008
    ..The present study was designed to elucidate the effect of TNP between -50 mmHg and -150 mmHg on microvascular blood flow in ischemic myocardium during hypothermia...
  27. ncbi Sternal stability at different negative pressures during vacuum-assisted closure therapy
    Arash Mokhtari
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Ann Thorac Surg 82:1063-7. 2006
    ..The aim of this study was to evaluate sternal stability during VAC application at seven negative pressures (-50 to -200 mm Hg) in a porcine wound model...
  28. doi Evaluation of continuous and intermittent myocardial topical negative pressure
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Sweden
    J Cardiovasc Med (Hagerstown) 9:813-9. 2008
    ..The present study was designed to elucidate the differences in microvascular blood flow in the left anterior descending artery area between continuous and intermittent myocardial topical negative pressure of -50 mmHg...
  29. doi Heparin does not seem to improve the function of pulmonary grafts for lung transplantation
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Skane University Hospital, Lund, Lund University, Sweden
    Scand Cardiovasc J 47:307-13. 2013
    ..Here, we raise the question of whether or not the use of heparin in HBDs improves the quality of the pulmonary grafts...
  30. doi Measurements of wound edge microvascular blood flow during negative pressure wound therapy using thermodiffusion and transcutaneous and invasive laser Doppler velocimetry
    Ola Borgquist
    Department of Anesthesiology and Intensive Care and Department of Ophthalmology, Lund University and Skåne University Hospital, Lund, Sweden
    Wound Repair Regen 19:727-33. 2011
    ..The pattern of response depends partly on the measurement technique used. The combination of hypoperfusion and hyperperfusion caused by NPWT may accelerate wound healing...
  31. doi Effects on drainage of the mediastinum and pleura during negative pressure wound therapy when using a rigid barrier to prevent heart rupture
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Int Wound J 8:454-8. 2011
    ..Significantly less drainage of the left pleura was possible when using conventional NPWT without the disc. The pericardium was equally good drained using NPWT with or without the disc...
  32. pmc Pressure transduction and fluid evacuation during conventional negative pressure wound therapy of the open abdomen and NPWT using a protective disc over the intestines
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Lund University Hospital, SE 221 85 Lund, Sweden
    BMC Surg 12:4. 2012
    ..In this study we compare pressure transduction and fluid evacuation of the open abdomen with conventional NPWT and NPWT with a protective disc...
  33. pmc Sternum wound contraction and distension during negative pressure wound therapy when using a rigid disc to prevent heart and lung rupture
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Lund University and Skåne University Hospital, Lund, Sweden
    J Cardiothorac Surg 6:42. 2011
    ..The aim of the present study was to determine whether a rigid barrier can be safely inserted over the heart with regard to the sternum wound edge movement...
  34. doi The influence of different sizes and types of wound fillers on wound contraction and tissue pressure during negative pressure wound therapy
    Erik Anesäter
    Department of Ophthalmology, Lund University and Skåne University Hospital, Lund, Sweden
    Int Wound J 8:336-42. 2011
    ..Gauze or large amounts of foam result in less wound contraction which may be beneficial, for example when NPWT causes pain to the patient...
  35. pmc A rigid barrier between the heart and sternum protects the heart and lungs against rupture during negative pressure wound therapy
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Lund University and Skåne University Hospital, Lund, Sweden
    J Cardiothorac Surg 6:90. 2011
    ..The aim of the present study was to investigate whether a rigid barrier protects the heart and lungs against injury during NPWT...
  36. doi Vacuum-assisted closure therapy for deep sternal wound infections: the impact of learning curve on survival and predictors for late mortality
    Johan Sjögren
    Department of Cardiothoracic Surgery, Lund University Hospital, SE 221 85 Lund, Sweden
    Int Wound J 5:216-23. 2008
    ..There was no difference in survival between our initial cases and later cases. Late diagnosis and prolonged wound therapy were identified as predictors for late mortality...
  37. ncbi Poststernotomy mediastinitis: a review of conventional surgical treatments, vacuum-assisted closure therapy and presentation of the Lund University Hospital mediastinitis algorithm
    Johan Sjögren
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Eur J Cardiothorac Surg 30:898-905. 2006
    ..Finally, we suggest a structured algorithm for using VAC therapy for treatment of poststernotomy mediastinitis in clinical practice...
  38. doi Negative-pressure wound therapy following cardiac surgery: bleeding complications and 30-day mortality in 176 patients with deep sternal wound infection
    Johan Sjögren
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund University, SE 221 85 Lund, Sweden
    Interact Cardiovasc Thorac Surg 12:117-20. 2011
    ..However, surgical experience is recommended when debriding sternal wounds and we recommend the use of a wound dressing, such as paraffin gauze, in order to protect the RV from direct contact with the polyurethane foam...
  39. ncbi Negative pressure wound therapy-associated tissue trauma and pain: a controlled in vivo study comparing foam and gauze dressing removal by immunohistochemistry for substance P and calcitonin gene-related peptide in the wound edge
    Malin Malmsjo
    Department of Ophthalmology, Lund University and Skåne University Hospital, Lund, Sweden
    Ostomy Wound Manage 57:30-5. 2011
    ..Using gauze may be one way of reducing NPWT dressing change-related pain. New wound fillers designed to optimize granulation tissue formation and minimize pain issues presumably will be developed in the near future...
  40. ncbi Hemodynamic effects of vacuum-assisted closure therapy in cardiac surgery: assessment using magnetic resonance imaging
    Rainer Petzina
    Department of Medicine, Lund University Hospital, Lund, Sweden
    J Thorac Cardiovasc Surg 133:1154-62. 2007
    ....
  41. doi Haemodynamic effects of negative pressure wound therapy when using a rigid barrier to prevent heart rupture
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Int Wound J 8:385-92. 2011
    ..The haemodynamic effects of NPWT in sternotomy wounds are slightly reduced by the presence of the rigid disc...
  42. doi Sympathetic and sensory nerve activation during negative pressure therapy of sternotomy wounds
    Christian Torbrand
    Department of Medicine, Lund University Hospital, Lund, Sweden
    Interact Cardiovasc Thorac Surg 7:1067-70. 2008
    ..In conclusion, the results suggest sympathetic nerve activation during NPWT. This may be the result of an increase in workload on the heart during the initial phase of NPWT...
  43. doi Microvascular blood flow changes in the small intestinal wall during conventional negative pressure wound therapy and negative pressure wound therapy using a protective disc over the intestines in laparostomy
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Lund University and Skåne University Hospital, Lund, Sweden
    Ann Surg 255:171-5. 2012
    ..Blood flow changes in the intestines during conventional negative pressure wound therapy (NPWT), and NPWT using a protective disc over the intestines in laparostomy...
  44. doi Sternocutaneous fistulas after cardiac surgery: incidence and late outcome during a ten-year follow-up
    Steinn Steingrimsson
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Ann Thorac Surg 88:1910-5. 2009
    ..Our objective was to identify the incidence of and risk factors for SCF, and to evaluate long-term survival...
  45. ncbi Blood flow changes in normal and ischemic myocardium during topically applied negative pressure
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Ann Thorac Surg 84:568-73. 2007
    ..The present study was designed to elucidate the effect of TNP on microvascular blood flow in the myocardium...
  46. pmc How to recondition ex vivo initially rejected donor lungs for clinical transplantation: clinical experience from lund university hospital
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Lund University and Skåne University Hospital, Lund, Sweden
    J Transplant 2011:754383. 2011
    ..In the following paper we present our clinical experience from the first six patients in the world. We also present the technique we used in detail with flowchart...
  47. doi The influence of low and high pressure levels during negative-pressure wound therapy on wound contraction and fluid evacuation
    Ola Borgquist
    Department of Ophthalmology, Lund University and Skåne University Hospital, Lund, Sweden
    Plast Reconstr Surg 127:551-9. 2011
    ..The aim of the present study was to examine wound contraction and fluid removal at different levels of negative pressure...
  48. ncbi Effect of vacuum-assisted closure on blood flow in the peristernal thoracic wall after internal mammary artery harvesting
    Rainer Petzina
    Department of Medicine, Lund University Hospital, Lund, Sweden
    Eur J Cardiothorac Surg 30:85-9. 2006
    ..The aim was to examine the effects of VAC negative pressure on peristernal soft tissue blood flow after internal mammary artery harvesting...
  49. doi Influence on pressure transduction when using different drainage techniques and wound fillers (foam and gauze) for negative pressure wound therapy
    Malin Malmsjo
    Department of Ophthalmology, Lund University and Skåne University Hospital, Lund, Sweden
    Int Wound J 7:406-12. 2010
    ..The choice of drainage technique may be particularly important in wounds with a large volume of exudate...
  50. ncbi Endothelin receptor-mediated vasodilatation: effects of organ culture
    David Nilsson
    Department of Medicine, Lund University Hospital, Lund, Sweden
    Eur J Pharmacol 579:233-40. 2008
    ..Down-regulation of endothelial endothelin ET(B) receptors may in part explain the increased endothelin ET(B) receptor-mediated vasoconstriction frequently studied in organ culture...
  51. ncbi Vacuum-assisted closure of the sternotomy wound: respiratory mechanics and ventilation
    Ronny Gustafsson
    Department of Cardiothoracic Surgery, University Hospital, Lund, Sweden
    Plast Reconstr Surg 117:1167-76. 2006
    ..The aim of the present study was to evaluate whether the application of six clinically relevant negative pressures between -50 mmHg and -175 mmHg to the sternotomy wound affects respiratory parameters in a porcine model...
  52. ncbi Individualizing the use of negative pressure wound therapy for optimal wound healing: a focused review of the literature
    Ola Borgquist
    Department of Ophthalmology, Lund University and Skåne University Hospital, Lund, Sweden
    Ostomy Wound Manage 57:44-54. 2011
    ..Prospective, controlled clinical studies are needed to compare NPWT to other advanced wound care protocols of care and to ascertain the effect of various NPWT methods and regimens on outcomes of care...
  53. doi Effects of foam or gauze on sternum wound contraction, distension and heart and lung damage during negative-pressure wound therapy of porcine sternotomy wounds
    Malin Malmsjo
    Department of Ophthalmology, Lund University Hospital, Lund, Sweden
    Interact Cardiovasc Thorac Surg 12:349-54. 2011
    ..The study shows that foam allows greater wound contraction and distension than gauze. This movement of the wound edges may cause damage to the underlying organs. There is less damage to the heart and lungs when using gauze than foam...
  54. pmc Macroscopic changes during negative pressure wound therapy of the open abdomen using conventional negative pressure wound therapy and NPWT with a protective disc over the intestines
    Sandra Lindstedt
    Department of Cardiothoracic Surgery, Lund University and Skåne University Hospital, Lund, Sweden
    BMC Surg 11:10. 2011
    ..In the present study we compare macroscopic changes after 12, 24, and 48 hours, using conventional NPWT and NPWT with a protective disc between the intestines and the vacuum source...
  55. ncbi The HeartShield device reduces the risk for right ventricular damage in patients with deep sternal wound infection
    Richard Ingemansson
    From the Departments of Cardiothoracic Surgery, and Ophthalmology, Lund University Hospital, Lund, Sweden
    Innovations (Phila) 9:137-41; discussion 141. 2014
    ..The use of a rigid barrier between the heart and the sharp sternal edges has been successfully tested on pigs. In the present article, we demonstrate increased safety in NPWT through the use of the HeartShield device...
  56. pmc A porcine model for acute ischaemic right ventricular dysfunction
    Pernille Haraldsen
    Department of Cardiothoracic Surgery, Anaesthesia and Intensive Care, Skane University Hospital, Lund University, Lund, Sweden
    Interact Cardiovasc Thorac Surg 18:43-8. 2014
    ..To establish an experimental model for acute ischaemic isolated right ventricular dysfunction and the subsequent haemodynamic changes...
  57. ncbi First human transplantation of a nonacceptable donor lung after reconditioning ex vivo
    Stig Steen
    Department of Cardiothoracic Surgery, Heart and Lung Division, Lund University Hospital, Lund, Sweden
    Ann Thorac Surg 83:2191-4. 2007
    ..This article describes an ex vivo method to recondition and transplant rejected donor lungs...
  58. ncbi The effect of intermittent and variable negative pressure wound therapy on wound edge microvascular blood flow
    Ola Borgquist
    Department of Opthalmology, Lund University, Lund, Sweden email
    Ostomy Wound Manage 56:60-7. 2010
    ..Cycling the negative pressure may be especially advantageous when treating poorly vascularized tissue. In cases where intermittent therapy causes patient discomfort, variable therapy may be superior...
  59. ncbi The impact of vacuum-assisted closure on long-term survival after post-sternotomy mediastinitis
    Johan Sjögren
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Ann Thorac Surg 80:1270-5. 2005
    ..Another objective was to identify risk factors for developing mediastinitis...