Ola Hansson

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. request reprint
    Hansson O, Ström K, Güner N, Wierup N, Sundler F, Hoglund P, et al. Inflammatory response in white adipose tissue in the non-obese hormone-sensitive lipase null mouse model. J Proteome Res. 2006;5:1701-10 pubmed
    ..A number of macrophage proteins, i.e., gal-3, Capg, and MCP-4, were expressed at increased levels and immunohistochemical analyses revealed an increased infiltration of F4/80+ cells. ..
  2. request reprint
    Hansson O, Donsmark M, Ling C, Nevsten P, Danfelter M, Andersen J, et al. Transcriptome and proteome analysis of soleus muscle of hormone-sensitive lipase-null mice. J Lipid Res. 2005;46:2614-23 pubmed
    ..The results of this study suggest that in the absence of HSL, a metabolic switch from reliance on lipid to carbohydrate energy substrates takes place, supporting an important role of HSL in soleus muscle lipid metabolism. ..
  3. Hansson O, Zhou Y, Renstrom E, Osmark P. Molecular function of TCF7L2: Consequences of TCF7L2 splicing for molecular function and risk for type 2 diabetes. Curr Diab Rep. 2010;10:444-51 pubmed publisher
    ..A clear picture of the molecular mechanism will be necessary to understand how an intronic variation in TCF7L2 can influence islet function. ..
  4. Zhou Y, Park S, Su J, Bailey K, Ottosson Laakso E, Shcherbina L, et al. TCF7L2 is a master regulator of insulin production and processing. Hum Mol Genet. 2014;23:6419-31 pubmed publisher
    ..These multiple targets in key pathways may explain why TCF7L2 has emerged as the gene showing one of the strongest associations with T2D. ..
  5. Zhou Y, Oskolkov N, Shcherbina L, Ratti J, Kock K, Su J, et al. HMGB1 binds to the rs7903146 locus in TCF7L2 in human pancreatic islets. Mol Cell Endocrinol. 2016;430:138-45 pubmed publisher
    ..These findings suggest that the rs7903146 locus might exert its enhancer function by interacting with HMGB1 in an allele dependent manner. ..

Detail Information

Publications5

  1. request reprint
    Hansson O, Ström K, Güner N, Wierup N, Sundler F, Hoglund P, et al. Inflammatory response in white adipose tissue in the non-obese hormone-sensitive lipase null mouse model. J Proteome Res. 2006;5:1701-10 pubmed
    ..A number of macrophage proteins, i.e., gal-3, Capg, and MCP-4, were expressed at increased levels and immunohistochemical analyses revealed an increased infiltration of F4/80+ cells. ..
  2. request reprint
    Hansson O, Donsmark M, Ling C, Nevsten P, Danfelter M, Andersen J, et al. Transcriptome and proteome analysis of soleus muscle of hormone-sensitive lipase-null mice. J Lipid Res. 2005;46:2614-23 pubmed
    ..The results of this study suggest that in the absence of HSL, a metabolic switch from reliance on lipid to carbohydrate energy substrates takes place, supporting an important role of HSL in soleus muscle lipid metabolism. ..
  3. Hansson O, Zhou Y, Renstrom E, Osmark P. Molecular function of TCF7L2: Consequences of TCF7L2 splicing for molecular function and risk for type 2 diabetes. Curr Diab Rep. 2010;10:444-51 pubmed publisher
    ..A clear picture of the molecular mechanism will be necessary to understand how an intronic variation in TCF7L2 can influence islet function. ..
  4. Zhou Y, Park S, Su J, Bailey K, Ottosson Laakso E, Shcherbina L, et al. TCF7L2 is a master regulator of insulin production and processing. Hum Mol Genet. 2014;23:6419-31 pubmed publisher
    ..These multiple targets in key pathways may explain why TCF7L2 has emerged as the gene showing one of the strongest associations with T2D. ..
  5. Zhou Y, Oskolkov N, Shcherbina L, Ratti J, Kock K, Su J, et al. HMGB1 binds to the rs7903146 locus in TCF7L2 in human pancreatic islets. Mol Cell Endocrinol. 2016;430:138-45 pubmed publisher
    ..These findings suggest that the rs7903146 locus might exert its enhancer function by interacting with HMGB1 in an allele dependent manner. ..