Lars Gustafson

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. pmc A factor analytic approach to symptom patterns in dementia
    Lars Gustafson
    Department of Geriatric Psychiatry, Clinical Sciences, Lund, Lund University, 221 85 Lund, Sweden
    Int J Alzheimers Dis 2011:632604. 2010
  2. ncbi request reprint The accuracy of short clinical rating scales in neuropathologically diagnosed dementia
    Lars Gustafson
    Department of Geriatric Psychiatry, Clinical Sciences, Lund, Lund University, Sweden
    Am J Geriatr Psychiatry 18:810-20. 2010
  3. ncbi request reprint Elevated plasma homocysteine level is not primarily related to Alzheimer's disease
    Karin Nilsson
    Departments of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 34:121-7. 2012
  4. doi request reprint Plasma homocysteine and cognition in elderly patients with dementia or other psychogeriatric diseases
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 30:198-204. 2010
  5. ncbi request reprint Plasma homocysteine and vascular disease in psychogeriatric patients
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 21:148-54. 2006
  6. ncbi request reprint Plasma homocysteine, cobalamin/folate status, and vascular disease in a large population of psychogeriatric patients
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 22:358-66. 2006
  7. ncbi request reprint Elevated plasma homocysteine concentration in elderly patients with mental illness is mainly related to the presence of vascular disease and not the diagnosis
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Division of Clinical Chemistry, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 24:162-8. 2007
  8. doi request reprint Plasma homocysteine, brain imaging and cognition in older patients with mental illness
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Int J Geriatr Psychiatry 27:409-14. 2012
  9. ncbi request reprint C-reactive protein: vascular risk marker in elderly patients with mental illness
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 26:251-6. 2008
  10. doi request reprint Plasma homocysteine and vascular disease in elderly patients with mental illness
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Clin Chem Lab Med 46:1556-61. 2008

Collaborators

Detail Information

Publications44

  1. pmc A factor analytic approach to symptom patterns in dementia
    Lars Gustafson
    Department of Geriatric Psychiatry, Clinical Sciences, Lund, Lund University, 221 85 Lund, Sweden
    Int J Alzheimers Dis 2011:632604. 2010
    ..A fourth symptom cluster was described by perception and expression of emotions. The factor analyses strongly support the construct validity of the diagnostic rating scales...
  2. ncbi request reprint The accuracy of short clinical rating scales in neuropathologically diagnosed dementia
    Lars Gustafson
    Department of Geriatric Psychiatry, Clinical Sciences, Lund, Lund University, Sweden
    Am J Geriatr Psychiatry 18:810-20. 2010
    ....
  3. ncbi request reprint Elevated plasma homocysteine level is not primarily related to Alzheimer's disease
    Karin Nilsson
    Departments of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 34:121-7. 2012
    ..A moderate elevation of plasma total homocysteine (tHcy) is considered a potential risk factor for Alzheimer's disease (AD)...
  4. doi request reprint Plasma homocysteine and cognition in elderly patients with dementia or other psychogeriatric diseases
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 30:198-204. 2010
    ..Increasing evidence indicates that vascular risk factors play a role in the development of cognitive impairment...
  5. ncbi request reprint Plasma homocysteine and vascular disease in psychogeriatric patients
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 21:148-54. 2006
    ....
  6. ncbi request reprint Plasma homocysteine, cobalamin/folate status, and vascular disease in a large population of psychogeriatric patients
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 22:358-66. 2006
    ..The objective of the present study is to obtain information on the role of cobalamin/folate status and vascular disease in different diagnoses of psychogeriatric patients and their association with plasma homocysteine (tHcy)...
  7. ncbi request reprint Elevated plasma homocysteine concentration in elderly patients with mental illness is mainly related to the presence of vascular disease and not the diagnosis
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Division of Clinical Chemistry, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 24:162-8. 2007
    ....
  8. doi request reprint Plasma homocysteine, brain imaging and cognition in older patients with mental illness
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Int J Geriatr Psychiatry 27:409-14. 2012
    ..Plasma tHcy has been reported to be associated with cognitive functions. The mechanism by which plasma tHcy may influence cognitive functions is not clear...
  9. ncbi request reprint C-reactive protein: vascular risk marker in elderly patients with mental illness
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 26:251-6. 2008
    ..Clarification of the role of vascular risk factors in dementia is important because most are modifiable, in contrast to other risk factors such as age and genetics...
  10. doi request reprint Plasma homocysteine and vascular disease in elderly patients with mental illness
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Clin Chem Lab Med 46:1556-61. 2008
    ..Furthermore, it seems possible that the control of conventional vascular risk factors could be guided by the level of plasma tHcy, serum cystatin C, serum N-terminal pro-brain natriuretic peptide, and serum C-reactive protein...
  11. doi request reprint Plasma homocysteine levels and different forms of vascular disease in patients with dementia and other psychogeriatric diseases
    Karin Nilsson
    Department of Psychogeriatrics and Clinical Science, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 27:88-95. 2009
    ..Total plasma homocysteine (tHcy) concentration is elevated in patients with psychogeriatric disease. There are many different determinants of plasma tHcy concentration, including the presence of vascular disease...
  12. ncbi request reprint Plasma homocysteine is elevated in elderly patients with memory complaints and vascular disease
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science and Laboratory Medicine, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 23:321-6. 2007
    ..The main objective of the present study was to investigate the relationship between plasma tHcy concentration and vascular disease in elderly patients with memory complaints...
  13. ncbi request reprint Homocysteine, cystatin C and N-terminal-pro brain natriuretic Peptide. Vascular risk markers in elderly patients with mental illness
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 25:88-96. 2008
    ..Clarification of the role of vascular risk factors in dementia is important because most are modifiable, in contrast to other risk factors such as age and genetics...
  14. ncbi request reprint Absolute quantification of cerebral blood flow in normal volunteers: correlation between Xe-133 SPECT and dynamic susceptibility contrast MRI
    Linda Knutsson
    Center for Medical Imaging and Physiology, MR Division, Lund University Hospital, Lund, Sweden
    J Magn Reson Imaging 26:913-20. 2007
    ..To compare absolute cerebral blood flow (CBF) estimates obtained by dynamic susceptibility contrast MRI (DSC-MRI) and Xe-133 SPECT...
  15. doi request reprint History of depression prior to Alzheimer's disease and vascular dementia verified post-mortem
    Hans Brunnström
    Department of Pathology, Lund University and Regional Laboratories Region Skåne, Lund, Sweden
    Arch Gerontol Geriatr 56:80-4. 2013
    ..The treatment modality of depression was similar in the groups. In conclusion, a history of depression prior to dementia is more common and more therapy-resistant in VaD than in AD...
  16. doi request reprint Survival in a large elderly population of patients with dementia and other forms of psychogeriatric diseases
    Karin Nilsson
    Department of Psychogeriatrics and Clinical Science, Institute of Laboratory Medicine, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 32:342-50. 2011
    ..Better knowledge of prognosis in elderly patients affected by dementia or mental illness should be of great importance in order to improve care plans and assist in medical decisions...
  17. doi request reprint Subjective memory complaints, neuropsychological performance and psychiatric variables in memory clinic attendees: a 3-year follow-up study
    Christina Elfgren
    Department of Geriatric Psychiatry, Clinical Sciences, Lund University Hospital, SE 221 85 Lund, Sweden
    Arch Gerontol Geriatr 51:e110-4. 2010
    ..We propose that subjective memory complaints might be influenced by the presence of psychosocial stress and feelings of anxiety disturbing the memory processes and interfering with the patients' evaluation of their memory function...
  18. ncbi request reprint Clinical utility of serum holotranscobalamin as a marker of cobalamin status in elderly patients with neuropsychiatric symptoms
    Karin Nilsson
    Department of Psychogeriatrics, Division of Clinical Chemistry, University Hospital, Lund, Sweden
    Clin Chem Lab Med 42:637-43. 2004
    ..The use of holoTC in the present study group did not give significant additional information other than that given by serum cobalamin and therefore cannot be recommended in this clinical setting...
  19. ncbi request reprint Plasma homocysteine concentration and its relation to symptoms of vascular disease in psychogeriatric patients
    Karin Nilsson
    Department of Psychogeriatrics and Laboratory Medicine, University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 20:35-41. 2005
    ..Psychogeriatric patients with a history of vascular disease exhibit a significantly higher plasma tHcy concentration than patients without vascular disease...
  20. doi request reprint The clinical use of N-terminal-pro brain natriuretic peptide in elderly patients with mental illness
    Karin Nilsson
    Department of Geriatric Psychiatry, Clinical Science, Lund University Hospital, S 22185 Lund, Sweden
    Clin Biochem 43:1282-6. 2010
    ..Vascular disease plays an important role in cognitive impairment in elderly patients with mental illness...
  21. ncbi request reprint Long-term follow-up in depressed patients treated with electroconvulsive therapy
    Aki Johanson
    Department of Psychogeriatrics, Lund University, Lund, Sweden
    J ECT 21:214-20. 2005
    ..These investigations were repeated in the 10 patients...
  22. doi request reprint Plasma homocysteine, apolipoprotein E status and vascular disease in elderly patients with mental illness
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Clin Chem Lab Med 48:129-35. 2010
    ..Apolipoprotein E (apoE) status is associated with cardiovascular disease and a major genetic risk factor is inheritance of the e4 allele. In the present study, we investigated the association between plasma tHcy and apoE status...
  23. ncbi request reprint Familial presenile dementia with bitemporal atrophy
    Ulla Passant
    Department of Psychogeriatrics, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 17:287-92. 2004
    ..This mutation was identified in all affected cases. The clinical picture of this family shows striking similarities not only to frontotemporal dementia but also to Alzheimer's disease...
  24. ncbi request reprint The heterogeneity of frontotemporal dementia with regard to initial symptoms, qEEG and neuropathology
    Ulla Passant
    Department of Psychogeriatrics, Lund University Hospital, Lund, Sweden
    Int J Geriatr Psychiatry 20:983-8. 2005
    ....
  25. ncbi request reprint Optimal use of markers for cobalamin and folate status in a psychogeriatric population
    Karin Nilsson
    Departments of Psychogeriatrics, University Hospital, Lund, Sweden
    Int J Geriatr Psychiatry 17:919-25. 2002
    ..It is therefore of importance to evaluate the optimal use of different markers of cobalamin/folate status in a psychogeriatric population...
  26. doi request reprint Alpha-synuclein multiplications with parkinsonism, dementia or progressive myoclonus?
    Andreas Puschmann
    Department of Neurology, Lund University Hospital, Sweden
    Parkinsonism Relat Disord 15:390-2. 2009
    ..This hypothesis is supported by the distribution of afflicted family members within the pedigree and by recently obtained genealogical information...
  27. ncbi request reprint Changes in frontal lobe activity with cognitive therapy for spider phobia
    Aki Johanson
    Department of Psychogeriatrics, University of Lund, Sweden
    Appl Neuropsychol 13:34-41. 2006
    ..The psychological improvement from cognitive therapy thus appears to be associated with activation of prefrontal cortex that varies closely with the demands for self-regulation of emotional reactivity...
  28. ncbi request reprint [Homocysteine--marker of vascular disease in elderly with mental illness]
    Björn Hultberg
    Klinisk kemi och farmakologi, Lund
    Lakartidningen 105:2576-8. 2008
  29. ncbi request reprint The Organic Brain Syndrome (OBS) scale: a systematic review
    Karin Björkman Björkelund
    Department of Anesthesiology and Intensive Care, Clinical Sciences, Lund University, Lund, Sweden
    Int J Geriatr Psychiatry 21:210-22. 2006
    ....
  30. ncbi request reprint Familial Lund frontotemporal dementia caused by C9ORF72 hexanucleotide expansion
    Elisabet Englund
    Department of Pathology, Lund University, Regional Laboratories Region Skåne, Lund, Sweden
    Neurobiol Aging 33:1850.e13-6. 2012
    ..Here we show that the large Lund pedigree with behavioral variant of frontotemporal dementia previously described with this disorder has an expansion in the recently described C9ORF72 locus on chromosome 9...
  31. ncbi request reprint Plasma homocysteine concentration relates to the severity but not to the duration of Alzheimer's disease
    Karin Nilsson
    Department of Psychogeriatrics, University Hospital, Lund, Sweden
    Int J Geriatr Psychiatry 19:666-72. 2004
    ..In the present study we have compared plasma tHcy concentrations at different times during the course of AD and with measures corresponding to the severity and the progress rate of AD...
  32. ncbi request reprint A clinico-pathological study of heart and brain lesions in vascular dementia
    Ulla Andin
    Department of Psychogeriatrics, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 19:222-8. 2005
    ..It is therefore necessary to identify the various types of vascular brain lesions for a correlation with clinical symptoms and for diagnostic purposes in the search for risk factors and therapeutic strategies...
  33. doi request reprint Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in adult psychiatry. A 20-year register study
    Lena Nylander
    Department of Clinical Sciences Psychiatry, Lund University, and Gillberg Neuropsychiatry Centre, University of Gothenburg, Sweden
    Nord J Psychiatry 67:344-50. 2013
    ..This study aimed to assess trends in diagnostic practice, diagnostic delay and comorbidity regarding ADHD and ASD in adult psychiatric patients...
  34. pmc Elevated plasma homocysteine level in vascular dementia reflects the vascular disease process
    Karin Nilsson
    Department of Psychogeriatrics, Clinical Science, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Dis Extra 3:16-24. 2013
    ..Patients with vascular dementia (VaD) exhibit particularly elevated levels of plasma total homocysteine (tHcy) compared to patients with other psychogeriatric diseases...
  35. pmc The use of N-terminal pro-brain natriuretic Peptide to evaluate vascular disease in elderly patients with mental illness
    Karin Nilsson
    Department of Geriatric Psychiatry, Clinical Science, Lund University Hospital, Lund, Sweden
    Dement Geriatr Cogn Dis Extra 2:10-8. 2012
    ..Serum N-terminal pro-brain natriuretic peptide (NT-proBNP) is regarded as a sensitive marker of cardiovascular disease. Vascular disease plays an important role in cognitive impairment...
  36. ncbi request reprint Regional cerebral blood flow and EEG in clinically diagnosed dementia with Lewy bodies and Alzheimer's disease
    Elisabet Londos
    Department of Psychogeriatrics, Lund University Hospital, SE 221 85, Lund, Sweden
    Arch Gerontol Geriatr 36:231-45. 2003
    ..The imaging results in clinDLB and clinAD were strikingly similar. The EEG and rCBF could not differentiate between cases with or without LB. The study illustrates the lack of specific changes of EEG and rCBF in cases with LB pathology...
  37. ncbi request reprint Right temporal lobe activation when listening to emotionally significant music
    Betty Bauer Alfredson
    Gerontology Research Centre, Lund, Sweden
    Appl Neuropsychol 11:161-6. 2004
    ..05) when standard music was compared to silence. For the emotional music, the right prefrontal area showed a decrease (p < .05). Emotional music thus activates right temporal and deactivates prefrontal regions in the right hemisphere...
  38. ncbi request reprint Relation between plasma homocysteine and Alzheimer's disease
    Karin Nilsson
    Department of Psychogeriatrics, Division of Clinical Chemistry, University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 14:7-12. 2002
    ..Several studies have shown that plasma total homocysteine (tHcy) concentration is elevated in Alzheimer's disease (AD). However, it is not clear whether elevated plasma tHcy is a primary cause or a consequence of AD...
  39. ncbi request reprint Folate deficiency is a common finding in psychogeriatric patients
    Björn Hultberg
    Department of Laboratory Medicine, Division of Clinical Chemistry, University Hospital, Lund, Sweden
    Aging Clin Exp Res 14:479-84. 2002
    ..The objective of the present study was to obtain detailed information on folate status in psychogeriatric patients and its association with elevated tHcy concentration...
  40. ncbi request reprint A long-term follow-up of clinical response and regional cerebral blood flow changes in depressed patients treated with ECT
    Ake Berggren
    Department of Psychology, Lund University, Lund, Sweden Department of Anaesthesia, Blekinge Hospital, SE 371 85 Karlskrona, Sweden Department of Psychiatry, Clinical Sciences, Lund University, Lund, Sweden Electronic address
    J Affect Disord 167:235-43. 2014
    ..We investigated the clinical response and regional cerebral blood flow changes in depressed in patients treated with (ECT) in a repeated longitudinal study...
  41. doi request reprint Publications on dementia in Medline 1974-2009: a quantitative bibliometric study
    Sten S Theander
    Department of Psychiatry, Clinical Sciences Lund, Lund University, 22185, Lund, Sweden
    Int J Geriatr Psychiatry 28:471-8. 2013
    ..The aim is to describe the development of the scientific literature on dementia...
  42. doi request reprint The birth and early evolution of the frontotemporal dementia (FTD) concept
    Arne Brun
    Department of Pathology, Lund University, Gyllenkroks Alle 27, Lund, SE 22224, Sweden
    J Mol Neurosci 45:324-9. 2011
    ..Since then, a dramatic increase in research activities and publications has rapidly expanded our knowledge in this field, a step necessary for the ultimate goal to find an effective treatment of this devastating disorder...
  43. ncbi request reprint Lack of association between plasma homocysteine and inflammation in psychogeriatric patients
    Karin Nilsson
    Department of Psychogeriatrics, Division of Clinical Chemistry, University Hospital, Lund, Sweden
    Dement Geriatr Cogn Disord 14:151-5. 2002
    ..Thus CRP concentration was not an independent predictor of plasma tHcy. Conclusion: The present study did not show any association between inflammatory status and plasma tHcy concentration in psychogeriatric patients...
  44. ncbi request reprint Folate and cobalamin levels as determinants of plasma homocysteine in different age groups of healthy controls and psychogeriatric patients
    Karin Nilsson
    Department of Psychogeriatrics, Division of Clinical Chemistry, University Hospital, Lund, Sweden
    Clin Chem Lab Med 41:681-5. 2003
    ....