Anders Grubb

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. pmc Improved estimation of glomerular filtration rate (GFR) by comparison of eGFRcystatin C and eGFRcreatinine
    Anders Grubb
    Department of Clinical Chemistry, Lund University Hospital, Lund, Sweden
    Scand J Clin Lab Invest 72:73-7. 2012
  2. pmc Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development
    Alexandra Bäcklund
    Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Scheeles vag 2, 171 77, Stockholm, Sweden
    Arthritis Res Ther 13:R54. 2011
  3. doi request reprint Non-invasive estimation of glomerular filtration rate (GFR). The Lund model: Simultaneous use of cystatin C- and creatinine-based GFR-prediction equations, clinical data and an internal quality check
    Anders Grubb
    Department of Clinical Chemistry, University Hospital, Lund, Sweden
    Scand J Clin Lab Invest 70:65-70. 2010
  4. pmc Cystatin C, a marker for successful aging and glomerular filtration rate, is not influenced by inflammation
    Anders Grubb
    Department of Clinical Chemistry, Lund University Hospital, Lund, Sweden
    Scand J Clin Lab Invest 71:145-9. 2011
  5. ncbi request reprint Fibrillogenic oligomers of human cystatin C are formed by propagated domain swapping
    Maria Wahlbom
    Department of Clinical Chemistry, Lund University Hospital, S 221 85 Lund, Sweden
    J Biol Chem 282:18318-26. 2007
  6. ncbi request reprint Simple cystatin C-based prediction equations for glomerular filtration rate compared with the modification of diet in renal disease prediction equation for adults and the Schwartz and the Counahan-Barratt prediction equations for children
    Anders Grubb
    Department of Clinical Chemistry, Competence Centre for Clinical Research, Department of Nephrology, University Hospital, Lund, Sweden
    Clin Chem 51:1420-31. 2005
  7. doi request reprint A new tool for predicting the probability of chronic kidney disease from a specific value of estimated GFR
    Jonas Bjork
    Competence Centre for Clinical Research, Lund University Hospital, Lund, Sweden
    Scand J Clin Lab Invest 70:327-33. 2010
  8. doi request reprint Revised equations for estimating glomerular filtration rate based on the Lund-Malmö Study cohort
    Jonas Bjork
    Competence Centre for Clinical Research, Skane University Hospital, Lund, Sweden
    Scand J Clin Lab Invest 71:232-9. 2011
  9. doi request reprint Variability in diagnostic accuracy can be estimated using simple population weighting
    Jonas Bjork
    Competence Centre for Clinical Research, Lund University Hospital, Barngatan 2, SE 221 85 Lund, Sweden
    J Clin Epidemiol 62:54-7. 2009
  10. doi request reprint Natriuretic peptides as indicators of cardiac remodeling in hypertensive patients
    Martin Magnusson
    Department of Cardiology, Malmo University Hospital, Lund University, Malmo, Sweden
    Blood Press 18:196-203. 2009

Collaborators

Detail Information

Publications22

  1. pmc Improved estimation of glomerular filtration rate (GFR) by comparison of eGFRcystatin C and eGFRcreatinine
    Anders Grubb
    Department of Clinical Chemistry, Lund University Hospital, Lund, Sweden
    Scand J Clin Lab Invest 72:73-7. 2012
    ....
  2. pmc Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development
    Alexandra Bäcklund
    Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Scheeles vag 2, 171 77, Stockholm, Sweden
    Arthritis Res Ther 13:R54. 2011
    ..In particular, the cysteine proteases have been proposed to be detrimental to the arthritic process and even immunomodulatory. A natural inhibitor of cysteine proteases is cystatin C...
  3. doi request reprint Non-invasive estimation of glomerular filtration rate (GFR). The Lund model: Simultaneous use of cystatin C- and creatinine-based GFR-prediction equations, clinical data and an internal quality check
    Anders Grubb
    Department of Clinical Chemistry, University Hospital, Lund, Sweden
    Scand J Clin Lab Invest 70:65-70. 2010
    ..If the GFRs predicted agree for a patient, the creatinine value is reliably connected to a specific GFR and can be used to follow changes in GFR of that patient...
  4. pmc Cystatin C, a marker for successful aging and glomerular filtration rate, is not influenced by inflammation
    Anders Grubb
    Department of Clinical Chemistry, Lund University Hospital, Lund, Sweden
    Scand J Clin Lab Invest 71:145-9. 2011
    ..The present work concerns the cystatin C levels and degree of inflammation in longitudinal studies of individual subjects without inflammation, who undergo elective surgery...
  5. ncbi request reprint Fibrillogenic oligomers of human cystatin C are formed by propagated domain swapping
    Maria Wahlbom
    Department of Clinical Chemistry, Lund University Hospital, S 221 85 Lund, Sweden
    J Biol Chem 282:18318-26. 2007
    ..Redox experiments using wild type and stabilized cystatin C strongly suggest that the oligomers, and thus probably the fibrils as well, are formed by propagated domain swapping rather than by assembly of domain-swapped cystatin C dimers...
  6. ncbi request reprint Simple cystatin C-based prediction equations for glomerular filtration rate compared with the modification of diet in renal disease prediction equation for adults and the Schwartz and the Counahan-Barratt prediction equations for children
    Anders Grubb
    Department of Clinical Chemistry, Competence Centre for Clinical Research, Department of Nephrology, University Hospital, Lund, Sweden
    Clin Chem 51:1420-31. 2005
    ..73 m(2))(-1). The present study analyzes whether these GFR prediction equations for adults and children might be replaced by simple prediction equations based on plasma concentrations of cystatin C...
  7. doi request reprint A new tool for predicting the probability of chronic kidney disease from a specific value of estimated GFR
    Jonas Bjork
    Competence Centre for Clinical Research, Lund University Hospital, Lund, Sweden
    Scand J Clin Lab Invest 70:327-33. 2010
    ..To demonstrate how patients' probability of having chronic kidney disease (CKD) stage 3-5 (measured GFR <60 mL/min/1.73 m(2)) can be predicted from a specific value of estimated glomerular filtration rate (eGFR)...
  8. doi request reprint Revised equations for estimating glomerular filtration rate based on the Lund-Malmö Study cohort
    Jonas Bjork
    Competence Centre for Clinical Research, Skane University Hospital, Lund, Sweden
    Scand J Clin Lab Invest 71:232-9. 2011
    ..73 m(2) by revising the Lund-Malmö (LM) equations, to elaborate on more complex forms to improve the LM and CKD-EPI equations further, and to assess benefits of adding lean body mass (LBM)...
  9. doi request reprint Variability in diagnostic accuracy can be estimated using simple population weighting
    Jonas Bjork
    Competence Centre for Clinical Research, Lund University Hospital, Barngatan 2, SE 221 85 Lund, Sweden
    J Clin Epidemiol 62:54-7. 2009
    ..g., chronic, referrals, or screening) under investigation. Simple weighted averages calculated from a single study sample may be used to assess variability in accuracy in different types of populations...
  10. doi request reprint Natriuretic peptides as indicators of cardiac remodeling in hypertensive patients
    Martin Magnusson
    Department of Cardiology, Malmo University Hospital, Lund University, Malmo, Sweden
    Blood Press 18:196-203. 2009
    ..This study was performed to evaluate the relationship between three different natriuretic peptides and left ventricular mass, function and diameter, and kidney function in patients with hypertension...
  11. ncbi request reprint Lack of the cysteine protease inhibitor cystatin C promotes atherosclerosis in apolipoprotein E-deficient mice
    Eva Bengtsson
    Department of Clinical Sciences, Malmo University Hospital, Lund University, Sweden
    Arterioscler Thromb Vasc Biol 25:2151-6. 2005
    ..It is present in the normal artery wall but severely reduced in human atherosclerotic lesions...
  12. pmc Stabilization, characterization, and selective removal of cystatin C amyloid oligomers
    Gustav Ostner
    Department of Clinical Chemistry, Lund University Hospital, S 22185 Lund, Sweden
    J Biol Chem 288:16438-50. 2013
    ..These could be used to selectively remove cystatin C dimers from biological fluids containing both dimers and monomers...
  13. doi request reprint High throughput testing of drug library substances and monoclonal antibodies for capacity to reduce formation of cystatin C dimers to identify candidates for treatment of hereditary cystatin C amyloid angiopathy
    Gustav Ostner
    Department of Clinical Chemistry, Lund University Hospital, Lund, Sweden
    Scand J Clin Lab Invest 71:676-82. 2011
    ....
  14. doi request reprint Elevated infection parameters and infection symptoms predict an acute coronary event
    Erkki Pesonen
    Department of Pediatric Cardiology, University Hospital, Lund, Sweden
    Ther Adv Cardiovasc Dis 2:419-24. 2008
    ..The etiology and significance of flu-like symptoms often appearing before myocardial infarction should be clarified...
  15. ncbi request reprint Prevention of domain swapping inhibits dimerization and amyloid fibril formation of cystatin C: use of engineered disulfide bridges, antibodies, and carboxymethylpapain to stabilize the monomeric form of cystatin C
    Maria Nilsson
    Department of Clinical Chemistry, University Hospital, S 22185 Lund, Sweden
    J Biol Chem 279:24236-45. 2004
    ..It was observed that catalytic amounts of both the monoclonal antibody and carboxymethylpapain could suppress dimerization...
  16. doi request reprint Different elimination patterns of beta-trace protein, beta2-microglobulin and cystatin C in haemodialysis, haemodiafiltration and haemofiltration
    Veronica Lindström
    Department of Clinical Chemistry, Lund University Hospital, Lund, Sweden
    Scand J Clin Lab Invest 68:685-91. 2008
    ..In this study, we used beta(2)-microglobulin, cystatin C and beta-trace protein, which differ in molecular mass and charge, to characterize the elimination patterns of three different dialysis modalities...
  17. ncbi request reprint New antimicrobial cystatin C-based peptide active against gram-positive bacterial pathogens, including methicillin-resistant Staphylococcus aureus and multiresistant coagulase-negative staphylococci
    Aftab Jasir
    Department of Clinical Chemistry, University Hospital, Lund, Sweden
    APMIS 111:1004-10. 2003
    ..aureus (MRSA) and multiantibiotic-resistant coagulase-negative staphylococci (CNS), suggesting that its mechanism of action differs from those of most currently used antibiotics...
  18. ncbi request reprint Glomerular filtration rate dependence of sieving of albumin and some neutral proteins in rat kidneys
    Ulla Lund
    Department of Nephrology, University Hospital, S 221 85 Lund, Sweden
    Am J Physiol Renal Physiol 284:F1226-34. 2003
    ..Furthermore, the glomerular small-pore radius assessed from endogenous (neutral) protein sieving data was found to be smaller than previously determined using dextran or Ficoll as test molecules...
  19. doi request reprint First certified reference material for cystatin C in human serum ERM-DA471/IFCC
    Anders Grubb
    Department of Clinical Chemistry, University Hospital, Lund, Sweden
    Clin Chem Lab Med 48:1619-21. 2010
    ..The certified cystatin C mass concentration in ERM-DA471/IFCC, if reconstituted according to the specified procedure, is 5.48 mg/L, the expanded uncertainty (k=2) being 0.15 mg/L...
  20. ncbi request reprint Lowered levels of serum albumin and HDL-cholesterol in children with a recent mild infection
    Elhadi H Aburawi
    Division of Pediatric Cardiology, Lund University Hospital, Lund
    Ann Med 38:154-60. 2006
    ..Infections are associated with atherogenic changes in serum.AIM. To elucidate effects of recent infections on risk factors for coronary heart disease in children...
  21. ncbi request reprint Serum cystatin C reflects glomerular endotheliosis in normal, hypertensive and pre-eclamptic pregnancies
    Helena Strevens
    Department of Obstetrics and Gynaecology, University Hospital, University of Lund, S 221 85 Lund, Sweden
    BJOG 110:825-30. 2003
    ..To study the correlation between serum cystatin C levels and renal structural changes in normal, hypertensive and pre-eclamptic pregnancy to evaluate it as a marker of the degree of renal involvement in pre-eclampsia...
  22. ncbi request reprint Cysteine proteases in Langerhans cells limits presentation of cartilage derived type II collagen for autoreactive T cells
    Meirav Holmdahl
    Department of Clinical Chemistry, Lund University, Sweden
    Int Immunol 16:717-26. 2004
    ....