P Gerdhem

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. ncbi request reprint Bone mass cannot be predicted by estimations of frailty in elderly ambulatory women
    Paul Gerdhem
    Department of Orthopaedics, Malmo University Hospital, Malmo, Sweden
    Gerontology 49:168-72. 2003
  2. ncbi request reprint Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women
    Paul Gerdhem
    Department of Orthopaedics, Malmo University Hospital, Sweden
    J Bone Miner Res 22:127-34. 2007
  3. ncbi request reprint Accelerometer-measured daily physical activity among octogenerians: results and associations to other indices of physical performance and bone density
    Paul Gerdhem
    Department of Orthopaedics, Karolinska University Hospital, Karolinska Institute, 141 86, Stockholm, Sweden
    Eur J Appl Physiol 102:173-80. 2008
  4. ncbi request reprint Rates of fracture in participants and non-participants in the Osteoporosis Prospective Risk Assessment study
    P Gerdhem
    Department of Orthopaedics, Karolinska University Hospital, Huddinge, Karolinska Institute, SE 14186 Stockholm, Sweden
    J Bone Joint Surg Br 89:1627-31. 2007
  5. ncbi request reprint Increased bone density and decreased bone turnover, but no evident alteration of fracture susceptibility in elderly women with diabetes mellitus
    P Gerdhem
    Department of Orthopaedics, Malmo University Hospital, Lund University, 205 02, Malmo, Sweden
    Osteoporos Int 16:1506-12. 2005
  6. ncbi request reprint Association between 25-hydroxy vitamin D levels, physical activity, muscle strength and fractures in the prospective population-based OPRA Study of Elderly Women
    P Gerdhem
    Department of Orthopedics, Malmo University Hospital, Lund University, Malmo, Sweden
    Osteoporos Int 16:1425-31. 2005
  7. doi request reprint Bone turnover markers are correlated with quantitative ultrasound of the calcaneus: 5-year longitudinal data
    J Lenora
    Department of Orthopaedics, Malmo University Hospital, Lund University, Malmo, Sweden
    Osteoporos Int 20:1225-32. 2009
  8. ncbi request reprint Influence of muscle strength, physical activity and weight on bone mass in a population-based sample of 1004 elderly women
    P Gerdhem
    Department of Orthopaedics, Malmo University Hospital, SE 205 02 Malmo, Sweden
    Osteoporos Int 14:768-72. 2003
  9. ncbi request reprint Prediction of bone loss using biochemical markers of bone turnover
    J Lenora
    Clinical and Molecular Osteoporosis Research Unit, Department of Orthopaedics, Malmo University Hospital, Lund University, SE 205 02, Malmo, Sweden
    Osteoporos Int 18:1297-305. 2007
  10. ncbi request reprint The prevention of osteoporotic fractures
    M K Karlsson
    Department of Orthopaedic Surgery, Malmo University Hospital, SE 20502 Malmo, Sweden
    J Bone Joint Surg Br 87:1320-7. 2005

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Bone mass cannot be predicted by estimations of frailty in elderly ambulatory women
    Paul Gerdhem
    Department of Orthopaedics, Malmo University Hospital, Malmo, Sweden
    Gerontology 49:168-72. 2003
    ..993 individuals were scored by at least one of four observers...
  2. ncbi request reprint Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women
    Paul Gerdhem
    Department of Orthopaedics, Malmo University Hospital, Sweden
    J Bone Miner Res 22:127-34. 2007
    ..During a mean 7-year follow-up, high homocysteine level was associated with mortality, but no clear association to fracture risk existed...
  3. ncbi request reprint Accelerometer-measured daily physical activity among octogenerians: results and associations to other indices of physical performance and bone density
    Paul Gerdhem
    Department of Orthopaedics, Karolinska University Hospital, Karolinska Institute, 141 86, Stockholm, Sweden
    Eur J Appl Physiol 102:173-80. 2008
    ..Questions on daily physical activity correlated modestly with accelerometer results in elderly women. Accelerometer results were not correlated to measures of balance, muscle strength and bone density...
  4. ncbi request reprint Rates of fracture in participants and non-participants in the Osteoporosis Prospective Risk Assessment study
    P Gerdhem
    Department of Orthopaedics, Karolinska University Hospital, Huddinge, Karolinska Institute, SE 14186 Stockholm, Sweden
    J Bone Joint Surg Br 89:1627-31. 2007
    ..001). Any study concerning the risk of fracture may attract those with experience of a fracture which explains the higher previous life-time incidence among the attendees. This factor may cause bias in epidemiological studies...
  5. ncbi request reprint Increased bone density and decreased bone turnover, but no evident alteration of fracture susceptibility in elderly women with diabetes mellitus
    P Gerdhem
    Department of Orthopaedics, Malmo University Hospital, Lund University, 205 02, Malmo, Sweden
    Osteoporos Int 16:1506-12. 2005
    ..The high bone mass and low bone turnover is not likely to have a strong influence on fracture susceptibility...
  6. ncbi request reprint Association between 25-hydroxy vitamin D levels, physical activity, muscle strength and fractures in the prospective population-based OPRA Study of Elderly Women
    P Gerdhem
    Department of Orthopedics, Malmo University Hospital, Lund University, Malmo, Sweden
    Osteoporos Int 16:1425-31. 2005
    ..However, a subgroup of women with 25OHD levels below 20 ng/ml had a tendency to an increased risk of fractures, which may be associated with an inferior physical activity and postural stability...
  7. doi request reprint Bone turnover markers are correlated with quantitative ultrasound of the calcaneus: 5-year longitudinal data
    J Lenora
    Department of Orthopaedics, Malmo University Hospital, Lund University, Malmo, Sweden
    Osteoporos Int 20:1225-32. 2009
    ..Baseline bone turnover markers correlated with baseline QUS as well as with 5-year prospective changes in QUS...
  8. ncbi request reprint Influence of muscle strength, physical activity and weight on bone mass in a population-based sample of 1004 elderly women
    P Gerdhem
    Department of Orthopaedics, Malmo University Hospital, SE 205 02 Malmo, Sweden
    Osteoporos Int 14:768-72. 2003
    ..Nevertheless, training in elderly women may have advantages by improving balance, co-ordination and mobility and therefore decreasing the risk of fractures...
  9. ncbi request reprint Prediction of bone loss using biochemical markers of bone turnover
    J Lenora
    Clinical and Molecular Osteoporosis Research Unit, Department of Orthopaedics, Malmo University Hospital, Lund University, SE 205 02, Malmo, Sweden
    Osteoporos Int 18:1297-305. 2007
    ..Several bone formation and resorption markers as well as urinary osteocalcin were modestly correlated to rate of bone density change...
  10. ncbi request reprint The prevention of osteoporotic fractures
    M K Karlsson
    Department of Orthopaedic Surgery, Malmo University Hospital, SE 20502 Malmo, Sweden
    J Bone Joint Surg Br 87:1320-7. 2005
  11. ncbi request reprint Association of the collagen type 1 (COL1A 1) Sp1 binding site polymorphism to femoral neck bone mineral density and wrist fracture in 1044 elderly Swedish women
    P Gerdhem
    Department of Orthopedics, Lund University, Malmo University Hospital, Malmo, Sweden
    Calcif Tissue Int 74:264-9. 2004
    ..The presence of at least one copy of the "s" allele was associated with lower femoral neck BMD and previous wrist fracture and in addition, it was related to an increased risk for wrist fracture...
  12. ncbi request reprint Effect of previous and present physical activity on bone mass in elderly women
    P Gerdhem
    Department of Orthopaedics, Malmo University Hospital, Malmo, Sweden
    Osteoporos Int 14:208-12. 2003
    ..Neither was it possible to find an effect of physical activity in those women with the highest BMD at all sites, suggesting that other factors are of greater importance for maintaining bone mass in elderly women...
  13. ncbi request reprint Effects of cigarette-smoking on bone mass as assessed by dual-energy X-ray absorptiometry and ultrasound
    P Gerdhem
    Department of Orthopaedics, Malmo University Hospital, Malmo, Sweden
    Osteoporos Int 13:932-6. 2002
    ..This difference is detected by DXA but not by ultrasound measurements of the calcaneus or the phalanges. The present data are encouraging since no bone mass differences were found between former and never-smokers...
  14. ncbi request reprint The impact of estradiol on bone mineral density is modulated by the specific estrogen receptor-alpha cofactor retinoblastoma-interacting zinc finger protein-1 insertion/deletion polymorphism
    Elin Grundberg
    Department of Medical Sciences, Uppsala University Hospital, Ing 70, 3 tr, Uppsala, Sweden
    J Clin Endocrinol Metab 92:2300-6. 2007
    ..Estrogens regulate bone mass by binding to the estrogen receptor (ER)-alpha as well as ER-beta. The specific ERalpha cofactor retinoblastoma-interacting zinc finger protein (RIZ)-1 enhances ERalpha function in the presence of estrogen...
  15. ncbi request reprint Vertebroplasty and kyphoplasty: New treatment strategies for fractures in the osteoporotic spine
    Magnus K Karlsson
    Clinical and Molecular Osteoporoses Research Unit, Department of Clinical Sciences, Lund University, SE 205 02 Malmo, Sweden
    Acta Orthop 76:620-7. 2005
    ..It is currently unknown, however, whether a vertebroplasty or a kyphoplasty gives a better outcome than nonoperative treatment, and whether the long-term results are as favorable as the short-term results...
  16. ncbi request reprint [Treatment of osteoporotic vertebral compression. Explosive interest for vertebroplasty and kyphoplasty]
    Magnus K Karlsson
    Ortopediska kliniken, Universitetssjukhuset MAS, SE 205 02 Malmo, Sweden
    Lakartidningen 102:1644-6, 1648. 2005
    ....
  17. ncbi request reprint Effect of fracture on bone turnover markers: a longitudinal study comparing marker levels before and after injury in 113 elderly women
    Kaisa K Ivaska
    Clinical and Molecular Osteoporosis Research Unit, Department of Orthopaedics, Lund University, Malmo University Hospital, Malmo, Sweden
    J Bone Miner Res 22:1155-64. 2007
    ..Markers were not altered in the immediate postfracture period but were clearly elevated during fracture repair. Recent fracture should thus be taken into account when markers are used in clinical practice...
  18. ncbi request reprint Urinary osteocalcin as a marker of bone metabolism
    Kaisa K Ivaska
    Institute of Biomedicine, Department of Anatomy, University of Turku, Turku, Finland
    Clin Chem 51:618-28. 2005
    ..OC is excreted into urine by glomerular filtration and can be found in urine as midmolecule fragments...
  19. doi request reprint Serial assessment of serum bone metabolism markers identifies women with the highest rate of bone loss and osteoporosis risk
    Kaisa K Ivaska
    Clinical and Molecular Osteoporosis Research Unit, Department of Orthopaedics, Malmo University Hospital, Malmo, Sweden
    J Clin Endocrinol Metab 93:2622-32. 2008
    ..One of the important challenges in the management of osteoporosis is to identify women who are at high risk of developing osteoporosis and fragility fractures...
  20. ncbi request reprint Biochemical markers of bone metabolism and prediction of fracture in elderly women
    Paul Gerdhem
    Departments of Orthopedics, Malmo University Hospital, Malmo, Sweeden
    J Bone Miner Res 19:386-93. 2004
    ..6 years). In elderly women, TRACP5b and urinary fragments of osteocalcin are promising new markers for prediction of fracture, in particular, vertebral fracture...
  21. doi request reprint Variation in the bone morphogenetic protein-2 gene: effects on fat and lean body mass in young and elderly women
    Fiona McGuigan
    Clinical and Molecular Osteoporosis Research Unit, Department of Clinical Sciences Malmo, Lund University, 205 02 Malmo, Sweden
    Eur J Endocrinol 158:661-8. 2008
    ..We investigated the relationship between BMP2 polymorphisms and body composition in young and elderly women...
  22. ncbi request reprint Variation in the BMP2 gene: bone mineral density and ultrasound in young adult and elderly women
    Fiona E McGuigan
    Clinical and Molecular Osteoporosis Research Unit, Department of Clinical Sciences Malmo, Lund University, Malmo, Sweden
    Calcif Tissue Int 81:254-62. 2007
    ....
  23. ncbi request reprint The relation between previous fractures and physical performance in elderly women
    Paul Gerdhem
    Department of Orthopaedics, Malmo University Hospital, Lund University, Malmo, Sweden
    Arch Phys Med Rehabil 87:914-7. 2006
    ..To examine the association between previous fracture and different aspects of physical performance...
  24. ncbi request reprint Biochemical markers of bone turnover are influenced by recently sustained fracture
    Karl J Obrant
    Clinical and Molecular Osteoporosis Research Unit, Department of Clinical Sciences, Malmo, Lund University, Sweden
    Bone 36:786-92. 2005
    ..20-0.33, P = 0.049-0.001) the more recently the fracture had been sustained. Women with low current physical activity had elevated levels of U-DPD/crea (P < 0.001) and one U-OC (P = 0.014), while the other markers were unaffected...
  25. ncbi request reprint Clinical history and biologic age predicted falls better than objective functional tests
    Paul Gerdhem
    Department of Orthopaedics, Malmo University Hospital, SE 205 02 Malmo, Sweden
    J Clin Epidemiol 58:226-32. 2005
    ..Fall risk assessment is important because the consequences, such as a fracture, may be devastating. The objective of this study was to find the test or tests that best predicted falls in a population-based sample of elderly women...
  26. ncbi request reprint Just one look, and fractures and death can be predicted in elderly ambulatory women
    Paul Gerdhem
    Department of Orthopaedics, Malmo University Hospital, Malmo, Sweden
    Gerontology 50:309-14. 2004
    ..The chronological age is clearly the strongest risk factor for fractures or death. Age as a concept can be described exactly as chronological age. Age in relative terms can be described as biological age...
  27. ncbi request reprint Bone mineral density in old age: the influence of age at menarche and menopause
    Paul Gerdhem
    Department of Orthopaedics, Malmo University Hospital, SE 205 02, Malmo, Sweden
    J Bone Miner Metab 22:372-5. 2004
    ..Age at menarche or menopause seems to be of limited or no importance as a risk factor for osteoporosis when subjects are age 75 or older...
  28. ncbi request reprint Interleukin-6 promoter polymorphism is associated with bone quality assessed by calcaneus ultrasound and previous fractures in a cohort of 75-year-old women
    Anna Nordström
    Sports Medicine, Department of Surgical and Perioperative Sciences, Umea University Hospital, 901 85, Umea, Sweden
    Osteoporos Int 15:820-6. 2004
    ..This association may be related primarily to an altered bone quality identified by QUS and not a lower bone mass. This is also the first demonstration of association of IL-6 gene polymorphism to calcaneal QUS...
  29. ncbi request reprint Seasonal variation in bone density in postmenopausal women
    Paul Gerdhem
    Department of Orthopaedics, Malmo University Hospital, SE 205 02 Malmo, Sweden
    J Clin Densitom 7:93-100. 2004
    ..In elderly women living at a northern latitude, BMD may be a few percent lower during the period July-December compared to the period January-June...
  30. ncbi request reprint Identification of novel proteolytic forms of osteocalcin in human urine
    Kaisa K Ivaska
    Department of Anatomy, Institute of Biomedicine, University of Turku, Kiinamyllynkatu 10, FIN 20520, Turku, Finland
    Biochem Biophys Res Commun 306:973-80. 2003
    ..Thus, the measurement of osteocalcin fragments in urine may have potential applications in diagnostics related to disorders of bone metabolism...
  31. ncbi request reprint Ultrasound of the phalanges is not related to a previous fracture. A comparison between ultrasound of the phalanges, calcaneus, and DXA of the spine and hip in 75-year-old women
    Paul Gerdhem
    Department of Orthopaedics, Malmo University Hospital, SE 205 02 Malmo, Sweden
    J Clin Densitom 5:159-66. 2002
    ..In summary, the present data indicate that US of the phalanges is not a usable tool for estimating fracture risk in an elderly female population...