Ola Forslund

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. ncbi request reprint Genetic diversity of cutaneous human papillomaviruses
    Ola Forslund
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital MAS, SE 20502 Malmo, Sweden
    J Gen Virol 88:2662-9. 2007
  2. pmc Cutaneous human papillomaviruses found in sun-exposed skin: Beta-papillomavirus species 2 predominates in squamous cell carcinoma
    Ola Forslund
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    J Infect Dis 196:876-83. 2007
  3. doi request reprint Efficacy of HPV DNA testing with cytology triage and/or repeat HPV DNA testing in primary cervical cancer screening
    Pontus Naucler
    Department of Medical Microbiology, Lund University, Malmo University Hospital, Malmo, Sweden
    J Natl Cancer Inst 101:88-99. 2009
  4. doi request reprint Seroreactivity to cutaneous human papillomaviruses among patients with nonmelanoma skin cancer or benign skin lesions
    Kristin Andersson
    Department of Medical Microbiology, Malmo University Hospital, Lund University, UMAS, Malmo, Sweden
    Cancer Epidemiol Biomarkers Prev 17:189-95. 2008
  5. doi request reprint Four novel human betapapillomaviruses of species 2 preferentially found in actinic keratosis
    Natasa Vasiljevic
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    J Gen Virol 89:2467-74. 2008
  6. pmc High prevalence of cutaneous human papillomavirus DNA on the top of skin tumors but not in "Stripped" biopsies from the same tumors
    Ola Forslund
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    J Invest Dermatol 123:388-94. 2004
  7. doi request reprint Diversity of human papillomaviruses in skin lesions
    Johanna Ekström
    Department of Laboratory Medicine, Lund University, SE 20502 Malmo, Sweden Departments of Laboratory Medicine, Medical Epidemiology and Biostatistics, Karolinska Institutet and Departments of Clinical Microbiology and Pathology, Karolinska Hospital, Stockholm, Sweden
    Virology 447:300-11. 2013
  8. ncbi request reprint Characterization of two novel cutaneous human papillomaviruses, HPV93 and HPV96
    Natasa Vasiljevic
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Sweden
    J Gen Virol 88:1479-83. 2007
  9. ncbi request reprint Nucleotide sequence and phylogenetic classification of candidate human papilloma virus type 92
    Ola Forslund
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    Virology 312:255-60. 2003
  10. doi request reprint Three novel papillomaviruses (HPV109, HPV112 and HPV114) and their presence in cutaneous and mucosal samples
    Johanna Ekström
    Department of Laboratory Medicine, Lund University, Malmo University Hospital, Entrance 78, 205 02 Malmo, Sweden
    Virology 397:331-6. 2010

Collaborators

Detail Information

Publications39

  1. ncbi request reprint Genetic diversity of cutaneous human papillomaviruses
    Ola Forslund
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital MAS, SE 20502 Malmo, Sweden
    J Gen Virol 88:2662-9. 2007
    ..As there are already 34 characterized HPV types described within the genera Betapapillomavirus and Gammapapillomavirus, they appear to be the most genetically diverse of the HPVs, apparently comprising at least 167 different HPV types...
  2. pmc Cutaneous human papillomaviruses found in sun-exposed skin: Beta-papillomavirus species 2 predominates in squamous cell carcinoma
    Ola Forslund
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    J Infect Dis 196:876-83. 2007
    ....
  3. doi request reprint Efficacy of HPV DNA testing with cytology triage and/or repeat HPV DNA testing in primary cervical cancer screening
    Pontus Naucler
    Department of Medical Microbiology, Lund University, Malmo University Hospital, Malmo, Sweden
    J Natl Cancer Inst 101:88-99. 2009
    ..Because the vast majority of women with positive cytology are also HPV DNA positive, screening strategies that use HPV DNA testing as the primary screening test may be more effective...
  4. doi request reprint Seroreactivity to cutaneous human papillomaviruses among patients with nonmelanoma skin cancer or benign skin lesions
    Kristin Andersson
    Department of Medical Microbiology, Malmo University Hospital, Lund University, UMAS, Malmo, Sweden
    Cancer Epidemiol Biomarkers Prev 17:189-95. 2008
    ..01). In conclusion, additional studies are required to clarify the biological meaning of seropositivity as a marker of cutaneous HPV infection and skin disease...
  5. doi request reprint Four novel human betapapillomaviruses of species 2 preferentially found in actinic keratosis
    Natasa Vasiljevic
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    J Gen Virol 89:2467-74. 2008
    ..However, as these types were found in only a few samples and in low amounts, a possible role in carcinogenesis remains elusive...
  6. pmc High prevalence of cutaneous human papillomavirus DNA on the top of skin tumors but not in "Stripped" biopsies from the same tumors
    Ola Forslund
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    J Invest Dermatol 123:388-94. 2004
    ..HPV DNA is common in superficial layers of lesions, but is not necessarily present throughout tumors...
  7. doi request reprint Diversity of human papillomaviruses in skin lesions
    Johanna Ekström
    Department of Laboratory Medicine, Lund University, SE 20502 Malmo, Sweden Departments of Laboratory Medicine, Medical Epidemiology and Biostatistics, Karolinska Institutet and Departments of Clinical Microbiology and Pathology, Karolinska Hospital, Stockholm, Sweden
    Virology 447:300-11. 2013
    ..Type-specific PCRs for 37 putative types from an additional 296 patients found only two of these putative types. In conclusion, skin lesions contain a large diversity of HPV types, but most appeared to be rare infections. ..
  8. ncbi request reprint Characterization of two novel cutaneous human papillomaviruses, HPV93 and HPV96
    Natasa Vasiljevic
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Sweden
    J Gen Virol 88:1479-83. 2007
    ..The E7 proteins of HPV92, 93 and 96 were found to bind the retinoblastoma protein (pRb). These results suggest a possible role for these HPV types in skin carcinogenesis that deserves further study...
  9. ncbi request reprint Nucleotide sequence and phylogenetic classification of candidate human papilloma virus type 92
    Ola Forslund
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    Virology 312:255-60. 2003
    ..The high viral load of HPV 92 in two BCCs differs from the low amount of HPV DNA reported from nonmelanoma skin cancers...
  10. doi request reprint Three novel papillomaviruses (HPV109, HPV112 and HPV114) and their presence in cutaneous and mucosal samples
    Johanna Ekström
    Department of Laboratory Medicine, Lund University, Malmo University Hospital, Entrance 78, 205 02 Malmo, Sweden
    Virology 397:331-6. 2010
    ..7% (48/2856) of the genital samples, whereas both HPV109 and 112 were rare viruses found at high viral loads only in their index samples...
  11. pmc Cutaneous human papillomavirus 88: remarkable differences in viral load
    Johanna Kullander
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    Int J Cancer 122:477-80. 2008
    ..All these had very low viral loads (<1 copy/10(3) cells) implying extreme biological variability in viral load...
  12. doi request reprint Pseudovirion-binding and neutralizing antibodies to cutaneous human papillomaviruses (HPV) correlated with the presence of HPV DNA in skin
    Helena Faust
    Department of Laboratory Medicine, Skane University Hospital, Lund University, Malmo, Sweden
    J Gen Virol 94:1096-103. 2013
    ..In summary, cutaneous HPVs also appear to induce a type-specific antibody response that correlates with the presence of HPV DNA and that can be detected with improved sensitivity using PsV-based serology...
  13. doi request reprint High throughput sequencing reveals diversity of Human Papillomaviruses in cutaneous lesions
    Johanna Ekström
    Division of Medical Microbiology, Department of Laboratory Medicine, Lund University, Skånes Universitetssjukhus, Malmo, Sweden
    Int J Cancer 129:2643-50. 2011
    ..In conclusion, high throughput sequencing was an effective means to identify both known and previously unknown HPV types in putatively HPV-associated lesions and has revealed an extended diversity of HPV types...
  14. pmc Unbiased approach for virus detection in skin lesions
    Davit Bzhalava
    Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e65953. 2013
    ..In conclusion, an unbiased approach for viral DNA detection in skin tumors has found that, although some new putative HPVs were found, known HPV types constituted most of the viral DNA. ..
  15. doi request reprint Prospective study of genital human papillomaviruses and nonmelanoma skin cancer
    Kristin Andersson
    Department of Laboratory Medicine, Clinical Microbiology, Lund University, Skane University Hospital, Malmo, Sweden
    Int J Cancer 133:1840-5. 2013
    ..As only a small proportion of seropositive subjects had evidence of the corresponding HPV DNA in the tumor, most of this excess risk is likely to be due to confounders associated with genital HPV infection...
  16. ncbi request reprint Human papillomavirus and Papanicolaou tests to screen for cervical cancer
    Pontus Naucler
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    N Engl J Med 357:1589-97. 2007
    ....
  17. doi request reprint Prospective study of human papillomavirus seropositivity and risk of nonmelanoma skin cancer
    Kristin Andersson
    Department of Medical Microbiology, Skane University Hospital, Malmo, Sweden
    Am J Epidemiol 175:685-95. 2012
    ..In summary, seropositivity for certain HPV types was associated with an increased risk for future development of SCC and BCC...
  18. ncbi request reprint Subtype HPV38b[FA125] demonstrates heterogeneity of human papillomavirus type 38
    Kristina Hazard
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    Int J Cancer 119:1073-7. 2006
    ..In summary, we found that HPV38 is heterogeneous and is one of so far only few HPVs that contain subtypes. The heterogeneity needs to be considered in studies of the biology of this virus...
  19. ncbi request reprint Improved detection of cutaneous human papillomavirus DNA by single tube nested 'hanging droplet' PCR
    Ola Forslund
    Department of Medical Microbiology, Malmo University Hospital, Lund University, SE 20502, Malmo, Sweden
    J Virol Methods 110:129-36. 2003
    ..The nested HPV PCR is more sensitive and capable of amplifying a broad spectrum of HPV types from skin tumours, but further improvements are needed before all HPV infections in skin can be detected by a single assay...
  20. doi request reprint Staphylococcus aureus and squamous cell carcinoma of the skin
    Johanna Kullander
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    Cancer Epidemiol Biomarkers Prev 18:472-8. 2009
    ..aureus. The study design used cannot determine whether the association implies that presence of S. aureus might influence carcinogenesis or whether it may imply that SCC has an increased susceptibility to S. aureus colonization...
  21. doi request reprint The Bcl-xL inhibitor of apoptosis is preferentially expressed in cutaneous squamous cell carcinoma compared with that in keratoacanthoma
    Natasa Vasiljevic
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    Int J Cancer 124:2361-6. 2009
    ..001). The lower expression of the antiapoptotic protein Bcl-xL in KA is consistent with a possible role of apoptosis in the regression of KA...
  22. ncbi request reprint Cutaneous human papillomaviruses persist on healthy skin
    Kristina Hazard
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    J Invest Dermatol 127:116-9. 2007
    ..Persistence was not significantly associated with age, sex, immunosuppressive treatment, history of warts, or genus of HPV. We conclude that cutaneous HPV infections commonly persist over several years on healthy skin...
  23. doi request reprint Metagenomic sequencing of "HPV-negative" condylomas detects novel putative HPV types
    Hanna Johansson
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, Malmo, Sweden
    Virology 440:1-7. 2013
    ..Complete genomes of Gammapillomavirus FA69 and SE87 were compiled. Metagenomic sequencing reveals that seemingly "HPV-negative" condylomas contain known and previously unknown HPV types...
  24. doi request reprint Comparison of use of vaginal HPV self-sampling and offering flexible appointments as strategies to reach long-term non-attending women in organized cervical screening
    Lotten Darlin
    Department of Obstetrics and Gynaecology, Skane University Hospital, Lund University, Lund, Sweden
    J Clin Virol 58:155-60. 2013
    ..Many cervical cancers occur among women who have not attended cervical screening. Strategies to reach non-attending women may improve the effectiveness of cervical screening programmes...
  25. doi request reprint Human papillomavirus typing in reporting of condyloma
    Erik Sturegard
    WHO HPV LabNet Global Reference Laboratory, Department of Clinical Microbiology, University and Regional Laboratories Region Skåne, Malmo, Sweden
    Sex Transm Dis 40:123-9. 2013
    ..If reporting could include HPV typing, the contribution by vaccine HPV types to condyloma burden could be monitored...
  26. ncbi request reprint Identification of human papillomavirus in keratoacanthomas
    Ola Forslund
    Department of Medical Microbiology, Malmo University Hospital, Lund University, SE 20502 Malmo, Sweden
    J Cutan Pathol 30:423-9. 2003
    ..Keratoacanthomas are benign, clinically distinct skin tumors that may infiltrate and show cellular atypia. A viral etiology has been suggested, and the aim was to search for human papillomavirus (HPV) in keratoacanthomas...
  27. ncbi request reprint Human papillomavirus subtypes are not uncommon
    Kristina Hazard
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, S 205 02 Malmo, Sweden
    Virology 362:6-9. 2007
    ..The number of types/putative types in each genus was 54, 58 and 103. Thus, there appears to exist at least 47 different subtypes/putative subtypes of HPV and they seem to be particularly common in the genus Beta-papillomavirus...
  28. doi request reprint Differences in transcriptional activity of cutaneous human papillomaviruses
    Natasa Vasiljevic
    Department of Medical Microbiology, Lund University, Malmo University Hospital, Malmo, Sweden
    Virus Res 137:213-9. 2008
    ..As there are variable UV-B responses among the HPV types, further studies of interactions between UV-B and HPV need to consider the HPV type...
  29. doi request reprint Absence of Epstein-Barr and cytomegalovirus infection in neuroblastoma cells by standard detection methodologies
    Daniel Sehic
    Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden
    Pediatr Blood Cancer 60:E91-3. 2013
    ..These standard methods did not detect infection by EBV or HCMV in NB cells in any tumor, while occasional immune cells were positive for EBV RNA or HCMV protein in four cases...
  30. pmc The 2010 global proficiency study of human papillomavirus genotyping in vaccinology
    Carina Eklund
    WHO HPV LabNet Global Reference Laboratory, Department of Clinical and Medical Microbiology, Laboratory Medicine Skåne, and Lund University, Malmo, Sweden
    J Clin Microbiol 50:2289-98. 2012
    ..In conclusion, continued global proficiency studies will be required for establishing comparable and reliable HPV genotyping services for vaccinology worldwide...
  31. doi request reprint Global Improvement in Genotyping of Human Papillomavirus DNA: the 2011 HPV LabNet International Proficiency Study
    Carina Eklund
    WHO HPV LabNet Global Reference Laboratory, Departments of Clinical and Medical Microbiology, Laboratory Medicine Skåne and Lund University, Malmo, Sweden
    J Clin Microbiol 52:449-59. 2014
    ..In conclusion, a continuing global proficiency program has documented worldwide improvement in the comparability and reliability of HPV genotyping assay performances. ..
  32. doi request reprint Vaginal self-sampling without preservative for human papillomavirus testing shows good sensitivity
    Lotten Darlin
    Department of Obstetrics and Gynaecology, Skane University Hospital, Lund University, Sweden
    J Clin Virol 56:52-6. 2013
    ..Self-sampling (SS) for HPV is effective for increasing coverage in screening programs, but requires expensive commercial sampling kits...
  33. pmc Lack of methylation in the upstream region of human papillomavirus type 6 from aerodigestive tract papillomas
    Agustín Enrique Ure
    Department of Laboratory Medicine, Section of Medical Microbiology, Lund University, Malmo, Sweden
    J Virol 86:13790-4. 2012
    ..All CpGs in the URR were unmethylated, from both basal/intermediate and superficial cells, suggesting that methylation is not involved in the regulation of transcription from the HPV6 URR, regardless of epithelial differentiation...
  34. doi request reprint Validation of multiplexed human papillomavirus serology using pseudovirions bound to heparin-coated beads
    Helena Faust
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    J Gen Virol 91:1840-8. 2010
    ..In summary, multiplexed HPV serology using mammalian-derived PsVs selected for native conformation by binding to heparin-coated beads was validated as a high-throughput HPV serological method for most of the analysed HPV types...
  35. doi request reprint The nasal mucosa contains a large spectrum of human papillomavirus types from the Betapapillomavirus and Gammapapillomavirus genera
    Ola Forslund
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, Malmo, Sweden
    J Infect Dis 208:1335-41. 2013
    ..Human papillomavirus (HPV) types from the Betapapillomavirus and Gammapapillomavirus genera are common at cutaneous sites. The aim of this study was to analyze the prevalence of these HPV types in oral and nasal samples...
  36. ncbi request reprint Population-based type-specific prevalence of high-risk human papillomavirus infection in middle-aged Swedish women
    Ola Forslund
    Department of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    J Med Virol 66:535-41. 2002
    ..The type-specific HPV prevalence found support in previous modeling studies suggesting that HPV screening may be a favorable cervical screening strategy...
  37. ncbi request reprint A prospective pilot study of antibodies against human papillomaviruses and cutaneous squamous cell carcinoma nested in the Oxford component of the European Prospective Investigation into Cancer and Nutrition
    Delphine Casabonne
    Cancer Epidemiology Unit, Richard Doll Building, University of Oxford, Old Road Campus, Roosevelt Drive, Headington, Oxford, OX3 7LF, United Kingdom
    Int J Cancer 121:1862-8. 2007
    ..Further and larger prospective studies are needed to clarify the role of HPV in the aetiology of cutaneous SCC...
  38. pmc Development of a sensitive and specific multiplex PCR method combined with DNA microarray primer extension to detect Betapapillomavirus types
    Tarik Gheit
    International Agency for Research on Cancer, Lyon, France
    J Clin Microbiol 45:2537-44. 2007
    ..This favorable feature and the high-throughput potential make this assay ideal for large-scale clinical and epidemiological studies aimed at determining the spectrum of cutaneous types in skin cancer...
  39. ncbi request reprint Penile intraepithelial neoplasia: results of photodynamic therapy
    John Paoli
    Department of Dermatology and Venereology, Sahlgrenska University Hospital, SE 41345 Goteborg, Sweden
    Acta Derm Venereol 86:418-21. 2006
    ..5 months). Photodynamic therapy is an alternative in the treatment of penile intraepithelial neoplasia, although prospective randomized trials are required to provide therapeutic guidelines...