C Fava

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. request reprint
    Fava C, Montagnana M, Almgren P, Rosberg L, Guidi G, Berglund G, et al. The functional variant of the CLC-Kb channel T481S is not associated with blood pressure or hypertension in Swedes. J Hypertens. 2007;25:111-6 pubmed
    ..Our data do not support a role of the CLC-Kb T481S polymorphism in BP regulation in Swedes. ..
  2. request reprint
    Fava C, Montagnana M, Almgren P, Rosberg L, Guidi G, Berglund G, et al. Association between adducin-1 G460W variant and blood pressure in Swedes is dependent on interaction with body mass index and gender. Am J Hypertens. 2007;20:981-9 pubmed
    ..001), diastolic BP (88.7 +/- 8.7 v 86.1 +/- 8.7 mm Hg; P < .001), and prevalence of hypertension (72.5% v 61.8 %; P = .001). Our data suggest that the G460W polymorphism influences BP when BMI and sex are taken into account. ..
  3. Fava C, Montagnana M, Almgren P, Rosberg L, Lippi G, Hedblad B, et al. The V433M variant of the CYP4F2 is associated with ischemic stroke in male Swedes beyond its effect on blood pressure. Hypertension. 2008;52:373-80 pubmed publisher
    ..A common CYP4F2 V433M polymorphism might increase the risk of incident ischemic stroke in male subjects only partially through its elevating effect on BP. Additional studies are needed to confirm these data. ..
  4. Fava C, Montagnana M, Almgren P, Hedblad B, Engstrom G, Berglund G, et al. The common functional polymorphism -50G>T of the CYP2J2 gene is not associated with ischemic coronary and cerebrovascular events in an urban-based sample of Swedes. J Hypertens. 2010;28:294-9 pubmed publisher
    ..Other studies are needed to elucidate if other polymorphisms in the same gene could have a role in BP homeostasis or incidence of cardiovascular events. ..
  5. Fava C, Danese E, Montagnana M, Sjögren M, Almgren P, Engstrom G, et al. Serine/threonine kinase 39 is a candidate gene for primary hypertension especially in women: results from two cohort studies in Swedes. J Hypertens. 2011;29:484-91 pubmed publisher
    ..The greater effect of the STK39 rs35929607A>G polymorphism in women with respect to men deserves further investigation. ..
  6. Fava C, Montagnana M, Danese E, Sjogren M, Almgren P, Engstrom G, et al. Vanin-1 T26I polymorphism, hypertension and cardiovascular events in two large urban-based prospective studies in Swedes. Nutr Metab Cardiovasc Dis. 2013;23:53-60 pubmed publisher
    ..Our data do not support a major role for the VNN1 T26I variant in determining BP level and incident ischemic events. ..
  7. Fava C, Montagnana M, Danese E, Sjögren M, Almgren P, Guidi G, et al. The functional variant V433M of the CYP4F2 and the metabolic syndrome in Swedes. Prostaglandins Other Lipid Mediat. 2012;98:31-6 pubmed publisher
    ..The first association either could be due to a false positive result or alternatively, different genetic background or population stratification could have hidden the effect of the polymorphism in the replication cohort. ..
  8. request reprint
    Fava C, Montagnana M, Rosberg L, Burri P, Almgren P, Jonsson A, et al. Subjects heterozygous for genetic loss of function of the thiazide-sensitive cotransporter have reduced blood pressure. Hum Mol Genet. 2008;17:413-8 pubmed
  9. Fava C, Montagnana M, Burri P, Almgren P, Minuz P, Hulthén U, et al. Determinants of kidney function in Swedish families: role of heritable factors. J Hypertens. 2008;26:1773-9 pubmed publisher
    ..The association of the circadian rhythm of blood pressure with kidney function in this sample deserves further investigation...

More Information

Publications13

  1. Fava C, Montagnana M, Danese E, Almgren P, Hedblad B, Engstrom G, et al. Homozygosity for the EPHX2 K55R polymorphism increases the long-term risk of ischemic stroke in men: a study in Swedes. Pharmacogenet Genomics. 2010;20:94-103 pubmed publisher
    ..Additional studies are needed to confirm these data and to elucidate the interaction between sex and the EPHX2 K55R polymorphism. ..
  2. Fava C, Montagnana M, Favaloro E, Guidi G, Lippi G. Obstructive sleep apnea syndrome and cardiovascular diseases. Semin Thromb Hemost. 2011;37:280-97 pubmed publisher
  3. Fava C, Danese E, Montagnana M, Sjögren M, Almgren P, Guidi G, et al. A variant upstream of the CDH13 adiponectin receptor gene and metabolic syndrome in Swedes. Am J Cardiol. 2011;108:1432-7 pubmed publisher
    ..In light of the role of cadherin-13 as a vascular receptor for adiponectin, our study supports the genetic basis for the role of adiponectin in MetS pathogenesis. ..
  4. Fava C, Montagnana M, Danese E, Sjögren M, Almgren P, Engstrom G, et al. The Renalase Asp37Glu polymorphism is not associated with hypertension and cardiovascular events in an urban-based prospective cohort: the Malmö Diet and cancer study. BMC Med Genet. 2012;13:57 pubmed
    ..The positive interaction with age suggest that the effect of the rs2296545 C > G polymorphism, if any, could vary between different ages. ..