E M Erfurth

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. doi request reprint Update in mortality in GH-treated patients
    Eva Marie Erfurth
    Department of Endocrinology, Skane University Hospital, SE 221 85 Lund, Sweden
    J Clin Endocrinol Metab 98:4219-26. 2013
  2. doi request reprint Hypothalamic involvement predicts cognitive performance and psychosocial health in long-term survivors of childhood craniopharyngioma
    Sigridur Fjalldal
    Department of Endocrinology, Skane University Hospital, SE 221 85 Lund, Sweden
    J Clin Endocrinol Metab 98:3253-62. 2013
  3. doi request reprint Pituitary disease mortality: is it fiction?
    Eva Marie Erfurth
    Department of Endocrinology, Skånes University Hospital, 221 85, Lund, Sweden
    Pituitary 16:402-12. 2013
  4. doi request reprint Mortality and morbidity in adult craniopharyngioma
    Eva Marie Erfurth
    Department of Endocrinology, Skånes University Hospital, 221 85, Lund, Sweden
    Pituitary 16:46-55. 2013
  5. ncbi request reprint Cerebrovascular disease in patients with pituitary tumors
    Eva Marie Erfurth
    Department of Endocrinology, Lund University Hospital, SE 221 85 Lund, Sweden
    Trends Endocrinol Metab 16:334-42. 2005
  6. ncbi request reprint Is growth hormone deficiency contributing to heart failure in patients with beta-thalassemia major?
    Eva Marie Erfurth
    Department of Endocrinology, Lund University Hospital, Lund, Sweden
    Eur J Endocrinol 151:161-6. 2004
  7. ncbi request reprint Epidemiology of adult growth hormone deficiency. Prevalence, incidence, mortality and morbidity
    E M Erfurth
    Department of Diabetes and Endocrinology, Lund University Hospital, Lund, Sweden
    Front Horm Res 33:21-32. 2005
  8. ncbi request reprint Risk factors for cerebrovascular deaths in patients operated and irradiated for pituitary tumors
    Eva Marie Erfurth
    Department of Internal Medicine, Division of Diabetology and Endocrinology, University Hospital, S 221 85 Lund, Sweden
    J Clin Endocrinol Metab 87:4892-9. 2002
  9. ncbi request reprint Incidence of a second tumor in hypopituitary patients operated for pituitary tumors
    E M Erfurth
    Department of Internal Medicine, Division of Diabetology and Endocrinology, University Hospital, S 221 85 Lund, Sweden
    J Clin Endocrinol Metab 86:659-62. 2001
  10. ncbi request reprint High incidence of cardiovascular disease and increased prevalence of cardiovascular risk factors in women with hypopituitarism not receiving growth hormone treatment: preliminary results
    E M Erfurth
    Department of Internal Medicine, University Hospital, Lund, Sweden
    Growth Horm IGF Res 9:21-4. 1999

Collaborators

Detail Information

Publications43

  1. doi request reprint Update in mortality in GH-treated patients
    Eva Marie Erfurth
    Department of Endocrinology, Skane University Hospital, SE 221 85 Lund, Sweden
    J Clin Endocrinol Metab 98:4219-26. 2013
    ..In these latter studies, an underlying serious condition was the most important factor for death, with central nervous system tumors (recurrent or new tumor) being the leading cause of mortality. ..
  2. doi request reprint Hypothalamic involvement predicts cognitive performance and psychosocial health in long-term survivors of childhood craniopharyngioma
    Sigridur Fjalldal
    Department of Endocrinology, Skane University Hospital, SE 221 85 Lund, Sweden
    J Clin Endocrinol Metab 98:3253-62. 2013
    ..Hypothalamic damage caused by craniopharyngioma (CP) is associated with poor functional outcome...
  3. doi request reprint Pituitary disease mortality: is it fiction?
    Eva Marie Erfurth
    Department of Endocrinology, Skånes University Hospital, 221 85, Lund, Sweden
    Pituitary 16:402-12. 2013
    ..This review will focus on; (1) pituitary insufficiencies and hormone substitutions, (2) modes of cranial radiotherapy, and (3) new techniques in the surgery of a pituitary adenoma...
  4. doi request reprint Mortality and morbidity in adult craniopharyngioma
    Eva Marie Erfurth
    Department of Endocrinology, Skånes University Hospital, 221 85, Lund, Sweden
    Pituitary 16:46-55. 2013
    ..The standardised overall mortality rate varies 2.88-9.28 in cohort studies. Patients with CP have a 3-19 fold higher cardiovascular mortality in comparison to the general population. Women with CP have an even higher risk...
  5. ncbi request reprint Cerebrovascular disease in patients with pituitary tumors
    Eva Marie Erfurth
    Department of Endocrinology, Lund University Hospital, SE 221 85 Lund, Sweden
    Trends Endocrinol Metab 16:334-42. 2005
    ....
  6. ncbi request reprint Is growth hormone deficiency contributing to heart failure in patients with beta-thalassemia major?
    Eva Marie Erfurth
    Department of Endocrinology, Lund University Hospital, Lund, Sweden
    Eur J Endocrinol 151:161-6. 2004
    ..We suggest that GH deficiency due to iron-induced damage to the hypothalamic-pituitary axis can contribute to heart failure in adult patients with beta-TM...
  7. ncbi request reprint Epidemiology of adult growth hormone deficiency. Prevalence, incidence, mortality and morbidity
    E M Erfurth
    Department of Diabetes and Endocrinology, Lund University Hospital, Lund, Sweden
    Front Horm Res 33:21-32. 2005
  8. ncbi request reprint Risk factors for cerebrovascular deaths in patients operated and irradiated for pituitary tumors
    Eva Marie Erfurth
    Department of Internal Medicine, Division of Diabetology and Endocrinology, University Hospital, S 221 85 Lund, Sweden
    J Clin Endocrinol Metab 87:4892-9. 2002
    ..There were no indications of significant differences in type of stroke, clinical stroke syndromes, or stroke fatality between the CVD patients and the population controls...
  9. ncbi request reprint Incidence of a second tumor in hypopituitary patients operated for pituitary tumors
    E M Erfurth
    Department of Internal Medicine, Division of Diabetology and Endocrinology, University Hospital, S 221 85 Lund, Sweden
    J Clin Endocrinol Metab 86:659-62. 2001
    ..This tendency was more emphasized for prostate cancer, but low numbers hamper a firm conclusion. These results may serve as a baseline for tumor risk among adult patients with pituitary insufficiency supplemented with GH...
  10. ncbi request reprint High incidence of cardiovascular disease and increased prevalence of cardiovascular risk factors in women with hypopituitarism not receiving growth hormone treatment: preliminary results
    E M Erfurth
    Department of Internal Medicine, University Hospital, Lund, Sweden
    Growth Horm IGF Res 9:21-4. 1999
    ..We conclude that adequate cardiovascular surveillance programmes are required for patients with pituitary insufficiency...
  11. ncbi request reprint Plasma concentrations of persistent organochlorines in relation to thyrotropin and thyroid hormone levels in women
    L Hagmar
    Department of Occupational and Environmental Medicine, University Hospital, 22185 Lund, Sweden
    Int Arch Occup Environ Health 74:184-8. 2001
    ..In this study the correlations between PCBs and thyrotropin (TSH) and thyroid hormone concentrations in plasma were assessed in adult women...
  12. ncbi request reprint Is there an increase in second brain tumours after surgery and irradiation for a pituitary tumour?
    E M Erfurth
    Department of Internal Medicine, University Hospital, Lund, Sweden
    Clin Endocrinol (Oxf) 55:613-6. 2001
    ..To assess the incidence of second brain tumours in patients operated and irradiated for pituitary tumours...
  13. ncbi request reprint Doubled mortality rate in irradiated patients reoperated for regrowth of a macroadenoma of the pituitary gland
    Eva Marie Erfurth
    Department of Internal Medicine, Division of Diabetology and Endocrinology, Lund University Hospital, S 221 85 Lund, Sweden
    Eur J Endocrinol 150:497-502. 2004
    ..Recently, we showed that in patients with craniopharyngiomas, tumour regrowth foreshadowed a fourfold risk increase for death. For patients with pituitary adenomas, the impact of regrowth on life expectancy is, however, not known...
  14. doi request reprint Ectopic recurrence of a craniopharyngioma in a 15-year-old girl 9 years after surgery and conventional radiotherapy: case report
    Maria Elfving
    Department of Clinical Sciences, Pediatric Unit, Lund University, Skane University Hospital, SE 221 85, Lund, Sweden
    Childs Nerv Syst 27:845-51. 2011
    ..Careful intra-operative procedure is probably crucial for preventing ectopic recurrences. The future will reveal if the transsphenoidal surgical route will put an end to ectopic tumor recurrence in patients with a craniopharyngioma...
  15. doi request reprint Deaths among adult patients with hypopituitarism: hypocortisolism during acute stress, and de novo malignant brain tumors contribute to an increased mortality
    P Burman
    Department of Endocrinology, Skånes University Hospital Malmö, University of Lund, Malmo, Sweden
    J Clin Endocrinol Metab 98:1466-75. 2013
    ..Patients with hypopituitarism have an increased standardized mortality rate. The basis for this has not been fully clarified...
  16. ncbi request reprint Is vascular mortality increased in hypopituitarism?
    E M Erfurth
    Department of Internal Medicine, Division of Endocrinology, University Hospital, SE 221 85 Lund, Sweden
    Pituitary 3:77-81. 2000
    ..This analysis is of a qualitative nature, and it is not possible to quantify to what extent the lacking validity may have affected the RR...
  17. pmc Normal pituitary hormone response to thyrotrophin and gonadotrophin releasing hormones in subjects exposed to elemental mercury vapour
    E M Erfurth
    Department of Internal Medicine, University Hospital, Lund, Sweden
    Br J Ind Med 47:639-44. 1990
    ..Increased plasma concentrations of selenium (Se) were associated with increased basal serum concentrations of TSH, decreased concentrations of basal serum cortisol, and decreased release of FSH...
  18. ncbi request reprint Nonfatal stroke, cardiac disease, and diabetes mellitus in hypopituitary patients on hormone replacement including growth hormone
    Helene Holmer
    Department of Internal Medicine, Centralsjukhuset, SE 291 85, Kristianstad, Sweden
    J Clin Endocrinol Metab 92:3560-7. 2007
    ..The impact of long-term GH replacement on cerebrovascular and cardiovascular diseases and diabetes mellitus in hypopituitary patients is unknown...
  19. doi request reprint Bone loss after childhood acute lymphoblastic leukaemia: an observational study with and without GH therapy
    Cecilia Follin
    Department of Endocrinology, Skane University Hospital, Lund, Sweden
    Eur J Endocrinol 164:695-703. 2011
    ..Bone mineral density (BMD) in survivors of acute lymphoblastic leukaemia (ALL) seems to vary with time, type of treatments and GH status. We aimed to evaluate BMD in ALL patients with GH deficiency (GHD), with and without GH therapy...
  20. ncbi request reprint Suppressed plasma prolactin response to thyrotropin-releasing hormone in hyperthyroidism reproduced by thyroxine but not by triiodothyronine administration to normal subjects
    E M Erfurth
    Department of Internal Medicine, University Hospital of Lund, Sweden
    Acta Endocrinol (Copenh) 117:241-8. 1988
    ..The site of action is suggested to be pituitary, but additional hypothalamic effects cannot be excluded...
  21. ncbi request reprint Risk for severe hypoglycaemia with unawareness in GH-deficient patients during the insulin tolerance test
    H Holmer
    Department of Internal Medicine, Hospital of Kristianstad, Lund, Sweden
    Clin Endocrinol (Oxf) 64:136-40. 2006
    ..The aim of the present study was to closely monitor the blood glucose level and to register the presence of symptoms and signs of hypoglycaemia during the ITT...
  22. ncbi request reprint Plasma levels of persistent organohalogens and hormone levels in adult male humans
    L Hagmar
    Department of Occupational and Environmental Medicine, University Hospital, Lund, Sweden
    Arch Environ Health 56:138-43. 2001
    ..High consumption of organohalogen-polluted fish did not appear to affect plasma concentrations of pituitary, thyroid, or testosterone hormone levels in male adults...
  23. ncbi request reprint Increased leptin and tumour necrosis factor alpha per unit fat mass in hypopituitary women without growth hormone treatment
    B Bulow
    Department of Medicine, Lund University, Lund, Sweden
    Eur J Endocrinol 145:737-42. 2001
    ....
  24. ncbi request reprint Physiological restitution after night-call duty in anaesthesiologists: impact on metabolic factors
    B Malmberg
    Department of Occupational and Environmental Medicine, Lund University Hospital, Lund, Sweden
    Acta Anaesthesiol Scand 51:823-30. 2007
    ....
  25. ncbi request reprint Effects of lead on the endocrine system in lead smelter workers
    E M Erfurth
    Department of Internal Medicine, University Hospital, Lund, Sweden
    Arch Environ Health 56:449-55. 2001
    ..Given that sperm parameters were not studied, the authors could not draw conclusions about fertility consequences...
  26. ncbi request reprint Release of prolactin as well as adrenocorticotropin after administration of arginine-vasopressin to healthy men
    E M Erfurth
    Department of Internal Medicine, University Hospital, Lund, Sweden
    Horm Metab Res 28:599-602. 1996
    ..It is concluded that AVP has the potency to release not only ACTH but also prolactin in healthy men...
  27. doi request reprint Hypothalamic involvement predicts cardiovascular risk in adults with childhood onset craniopharyngioma on long-term GH therapy
    Helene Holmer
    Department of Internal Medicine, Centralsjukhuset, Kristianstad, Lund, Sweden
    Eur J Endocrinol 161:671-9. 2009
    ..No previous study on long-term GH therapy in adults with childhood onset (CO) craniopharyngioma was identified...
  28. ncbi request reprint High incidence of mental disorders, reduced mental well-being and cognitive function in hypopituitary women with GH deficiency treated for pituitary disease
    Birgitta Bulow
    Departments of Diabetology and Endocrinology and Occupational and Environmental Medicine, University Hospital, Lund, Sweden
    Clin Endocrinol (Oxf) 56:183-93. 2002
    ..In the present study we investigated the incidence of mental disorders and the prevalence of mental distress and cognitive dysfunction in hypopituitary women with untreated GH deficiency compared to population-based controls...
  29. ncbi request reprint Fracture incidence in GH-deficient patients on complete hormone replacement including GH
    Helene Holmer
    Department of Internal Medicine, Centralsjukhuset, Kristianstad, Sweden
    J Bone Miner Res 22:1842-50. 2007
    ..Studying fracture incidence in 832 patients on GH therapy and 2581 matched population controls, we recorded a doubled fracture risk in CO GHD women, but a significantly lower fracture risk in AO GHD men...
  30. doi request reprint Reduced energy expenditure and impaired feeding-related signals but not high energy intake reinforces hypothalamic obesity in adults with childhood onset craniopharyngioma
    Helene Holmer
    Department of Internal Medicine, Cenral Hospital, Kristianstad, Sweden
    J Clin Endocrinol Metab 95:5395-402. 2010
    ..It is not yet clarified whether the obesity is due to alterations in energy expenditure, i.e. basal metabolic rate (BMR) and physical activity, or to increased energy intake (EI)...
  31. ncbi request reprint The role of estrogen in the TSH and prolactin responses to thyrotropin-releasing hormone in postmenopausal as compared to premenopausal women
    E M Erfurth
    Department of Internal Medicine of Lund, University Hospital, Sweden
    Horm Metab Res 24:528-31. 1992
    ..In conclusion, a weak but not significant decrease in the TSH response to TRH in postmenopausal women may be explained by the lower endogenous estradiol level...
  32. ncbi request reprint The gender differences in growth hormone-binding protein and leptin persist in 80-year-old men and women and is not caused by sex hormones
    B Bulow
    Department of Medicine, Lund University, Lund, Sweden
    Clin Endocrinol (Oxf) 59:482-6. 2003
    ..The interrelationships between leptin, insulin, GHBP and fat mass in this age group were also investigated...
  33. ncbi request reprint Survivors of childhood acute lymphoblastic leukaemia, with radiation-induced GH deficiency, exhibit hyperleptinaemia and impaired insulin sensitivity, unaffected by 12 months of GH treatment
    Birgitta Bulow
    Department of Medicine, Lund University, Lund, Sweden
    Clin Endocrinol (Oxf) 61:683-91. 2004
    ..It is not known whether the observed risk for adiposity in these patients is associated with impaired insulin sensitivity and whether the insulin sensitivity is affected by GH replacement therapy...
  34. ncbi request reprint Adult survivors of childhood acute lymphoblastic leukaemia with GH deficiency have normal self-rated quality of life but impaired neuropsychological performance 20 years after cranial irradiation
    Katarina Link
    Department of Endocrinology, Lund University Hospital, Lund, Sweden
    Clin Endocrinol (Oxf) 65:617-25. 2006
    ..Because survival rates have improved markedly, the long-term complications, such as GH deficiency (GHD) and neuropsychological impairment, have become increasingly important...
  35. doi request reprint Cardiovascular risk, cardiac function, physical activity, and quality of life with and without long-term growth hormone therapy in adult survivors of childhood acute lymphoblastic leukemia
    Cecilia Follin
    Department of Endocrinology, Lund and Malmö University Hospital, Lund University, SE 221 85 Lund, Sweden
    J Clin Endocrinol Metab 95:3726-35. 2010
    ..GH therapy may result in poorer outcome regarding cardiovascular (CV) and particularly cardiac effects than in patients with hypothalamic-pituitary disease...
  36. ncbi request reprint Associations between CB-153 and p,p'-DDE and hormone levels in serum in middle-aged and elderly men
    Lars Rylander
    Division of Occupational and Environmental Medicine and Psychiatric Epidemiology, Department of Laboratory Medicine, Lund University, Lund University Hospital, SE 221 85 Lund, Sweden
    Chemosphere 65:375-81. 2006
    ....
  37. ncbi request reprint Improvement in cardiac systolic function and reduced prevalence of metabolic syndrome after two years of growth hormone (GH) treatment in GH-deficient adult survivors of childhood-onset acute lymphoblastic leukemia
    Cecilia Follin
    Department of Endocrinology, Lund University Hospital, SE 221 85 Lund, Sweden
    J Clin Endocrinol Metab 91:1872-5. 2006
    ....
  38. ncbi request reprint Growth hormone deficiency predicts cardiovascular risk in young adults treated for acute lymphoblastic leukemia in childhood
    Katarina Link
    Department of Endocrinology, Lund University Hospital, SE 221 85 Lund, Sweden
    J Clin Endocrinol Metab 89:5003-12. 2004
    ..We suggest that GH deficiency, induced by CRT, is a primary cause for this because strong correlations between the stimulated GH peak and several of the cardiovascular risk factors were observed...
  39. ncbi request reprint The utility of the growth hormone (GH) releasing hormone-arginine test for diagnosing GH deficiency in adults with childhood acute lymphoblastic leukemia treated with cranial irradiation
    Jonas Bjork
    Center for Clinical Research, Lund University Hospital, SE 221 85 Lund, Sweden
    J Clin Endocrinol Metab 90:6048-54. 2005
    ..The insulin tolerance test (ITT) is the current standard diagnostic test for the diagnosis of adult GH deficiency (GHD), but alternative tests, such as the GHRH-arginine test, have been proposed...
  40. ncbi request reprint Baseline characteristics and response to 2 years of growth hormone (GH) replacement of hypopituitary patients with GH deficiency due to adult-onset craniopharyngioma in comparison with patients with nonfunctioning pituitary adenoma: data from KIMS (Pfizer
    Johan Verhelst
    General Hospital Middleheim, Antwerp, Belgium
    J Clin Endocrinol Metab 90:4636-43. 2005
    ..To analyze this difference, we used the KIMS database (Pfizer International Metabolic Database) comparing CP and NFPA patients in terms of baseline characteristics and responses to GH replacement...
  41. ncbi request reprint The clinical, metabolic and endocrine features and the quality of life in adults with childhood-onset craniopharyngioma compared with adult-onset craniopharyngioma
    Pat Kendall-Taylor
    University of Newcastle, UK
    Eur J Endocrinol 152:557-67. 2005
    ..Craniopharyngioma is a parasellar tumour that, although benign, tends to behave aggressively. It can occur at any age but most commonly presents in childhood or adolescence...
  42. ncbi request reprint Changes in height, weight, and body mass index in children with craniopharyngioma after three years of growth hormone therapy: analysis of KIGS (Pfizer International Growth Database)
    Mitchell Geffner
    The Saban Research Institute of Childrens Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, California 90027, USA
    J Clin Endocrinol Metab 89:5435-40. 2004
    ....
  43. ncbi request reprint Long-term improvement of quality of life during growth hormone (GH) replacement therapy in adults with GH deficiency, as measured by questions on life satisfaction-hypopituitarism (QLS-H)
    Myriam Rosilio
    Lilly Research Laboratories, Eli Lilly and Co, Indianapolis, Indiana 46285, USA
    J Clin Endocrinol Metab 89:1684-93. 2004
    ..The authors suggest that evaluation of QoL should be a part of the routine clinical management of adult GH-deficient patients, complementing the measurement of surrogate biological markers or other clinical end points...