Joakim Dillner

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. doi request reprint Efficacy of HPV DNA testing with cytology triage and/or repeat HPV DNA testing in primary cervical cancer screening
    Pontus Naucler
    Department of Medical Microbiology, Lund University, Malmo University Hospital, Malmo, Sweden
    J Natl Cancer Inst 101:88-99. 2009
  2. pmc Long term predictive values of cytology and human papillomavirus testing in cervical cancer screening: joint European cohort study
    Joakim Dillner
    Lund University, Medical Microbiology, University Hospital MAS, 205 02 Malmo, Sweden
    BMJ 337:a1754. 2008
  3. ncbi request reprint [Swedish consensus on cervix cancer vaccination. Vaccination programs for eradication of HPV16/18 should be initiated in elementary schools]
    Joakim Dillner
    WHO globalt referenslaboratorium för HPV, Universitetssjukhuset MAS, Malmo
    Lakartidningen 103:3377-9. 2006
  4. pmc Four year efficacy of prophylactic human papillomavirus quadrivalent vaccine against low grade cervical, vulvar, and vaginal intraepithelial neoplasia and anogenital warts: randomised controlled trial
    Joakim Dillner
    Depatment of Laboratory Medicine, Lund University, Malmo, Sweden
    BMJ 341:c3493. 2010
  5. doi request reprint Seroreactivity to cutaneous human papillomaviruses among patients with nonmelanoma skin cancer or benign skin lesions
    Kristin Andersson
    Department of Medical Microbiology, Malmo University Hospital, Lund University, UMAS, Malmo, Sweden
    Cancer Epidemiol Biomarkers Prev 17:189-95. 2008
  6. pmc Cutaneous human papillomaviruses found in sun-exposed skin: Beta-papillomavirus species 2 predominates in squamous cell carcinoma
    Ola Forslund
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    J Infect Dis 196:876-83. 2007
  7. doi request reprint Genotyping of human papillomavirus in triaging of low-grade cervical cytology
    Anna Söderlund-Strand
    World Health Organization HPV LabNet Global Reference Laboratory, Department of Clinical Microbiology, Skane University Hospital, Malmo, Sweden
    Am J Obstet Gynecol 205:145.e1-6. 2011
  8. doi request reprint Four novel human betapapillomaviruses of species 2 preferentially found in actinic keratosis
    Natasa Vasiljevic
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    J Gen Virol 89:2467-74. 2008
  9. doi request reprint Diversity of human papillomaviruses in skin lesions
    Johanna Ekström
    Department of Laboratory Medicine, Lund University, SE 20502 Malmo, Sweden Departments of Laboratory Medicine, Medical Epidemiology and Biostatistics, Karolinska Institutet and Departments of Clinical Microbiology and Pathology, Karolinska Hospital, Stockholm, Sweden
    Virology 447:300-11. 2013
  10. ncbi request reprint Human papillomavirus and Papanicolaou tests to screen for cervical cancer
    Pontus Naucler
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    N Engl J Med 357:1589-97. 2007

Detail Information

Publications105 found, 100 shown here

  1. doi request reprint Efficacy of HPV DNA testing with cytology triage and/or repeat HPV DNA testing in primary cervical cancer screening
    Pontus Naucler
    Department of Medical Microbiology, Lund University, Malmo University Hospital, Malmo, Sweden
    J Natl Cancer Inst 101:88-99. 2009
    ..Because the vast majority of women with positive cytology are also HPV DNA positive, screening strategies that use HPV DNA testing as the primary screening test may be more effective...
  2. pmc Long term predictive values of cytology and human papillomavirus testing in cervical cancer screening: joint European cohort study
    Joakim Dillner
    Lund University, Medical Microbiology, University Hospital MAS, 205 02 Malmo, Sweden
    BMJ 337:a1754. 2008
    ..To obtain large scale and generalisable data on the long term predictive value of cytology and human papillomavirus (HPV) testing for development of cervical intraepithelial neoplasia grade 3 or cancer (CIN3+)...
  3. ncbi request reprint [Swedish consensus on cervix cancer vaccination. Vaccination programs for eradication of HPV16/18 should be initiated in elementary schools]
    Joakim Dillner
    WHO globalt referenslaboratorium för HPV, Universitetssjukhuset MAS, Malmo
    Lakartidningen 103:3377-9. 2006
  4. pmc Four year efficacy of prophylactic human papillomavirus quadrivalent vaccine against low grade cervical, vulvar, and vaginal intraepithelial neoplasia and anogenital warts: randomised controlled trial
    Joakim Dillner
    Depatment of Laboratory Medicine, Lund University, Malmo, Sweden
    BMJ 341:c3493. 2010
    ..To evaluate the prophylactic efficacy of the human papillomavirus (HPV) quadrivalent vaccine in preventing low grade cervical, vulvar, and vaginal intraepithelial neoplasias and anogenital warts (condyloma acuminata)...
  5. doi request reprint Seroreactivity to cutaneous human papillomaviruses among patients with nonmelanoma skin cancer or benign skin lesions
    Kristin Andersson
    Department of Medical Microbiology, Malmo University Hospital, Lund University, UMAS, Malmo, Sweden
    Cancer Epidemiol Biomarkers Prev 17:189-95. 2008
    ..01). In conclusion, additional studies are required to clarify the biological meaning of seropositivity as a marker of cutaneous HPV infection and skin disease...
  6. pmc Cutaneous human papillomaviruses found in sun-exposed skin: Beta-papillomavirus species 2 predominates in squamous cell carcinoma
    Ola Forslund
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    J Infect Dis 196:876-83. 2007
    ....
  7. doi request reprint Genotyping of human papillomavirus in triaging of low-grade cervical cytology
    Anna Söderlund-Strand
    World Health Organization HPV LabNet Global Reference Laboratory, Department of Clinical Microbiology, Skane University Hospital, Malmo, Sweden
    Am J Obstet Gynecol 205:145.e1-6. 2011
    ....
  8. doi request reprint Four novel human betapapillomaviruses of species 2 preferentially found in actinic keratosis
    Natasa Vasiljevic
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    J Gen Virol 89:2467-74. 2008
    ..However, as these types were found in only a few samples and in low amounts, a possible role in carcinogenesis remains elusive...
  9. doi request reprint Diversity of human papillomaviruses in skin lesions
    Johanna Ekström
    Department of Laboratory Medicine, Lund University, SE 20502 Malmo, Sweden Departments of Laboratory Medicine, Medical Epidemiology and Biostatistics, Karolinska Institutet and Departments of Clinical Microbiology and Pathology, Karolinska Hospital, Stockholm, Sweden
    Virology 447:300-11. 2013
    ..Type-specific PCRs for 37 putative types from an additional 296 patients found only two of these putative types. In conclusion, skin lesions contain a large diversity of HPV types, but most appeared to be rare infections. ..
  10. ncbi request reprint Human papillomavirus and Papanicolaou tests to screen for cervical cancer
    Pontus Naucler
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    N Engl J Med 357:1589-97. 2007
    ....
  11. ncbi request reprint Chlamydia trachomatis infection and persistence of human papillomavirus
    Ilvars Silins
    Department of Medical Microbiology, Lund University, University Hospital at Malmö, Sweden
    Int J Cancer 116:110-5. 2005
    ..trachomatis infection (relative risk in multivariate model = 2.09; 95% confidence interval = 1.05-4.18). We conclude that persistence of oncogenic HPV infections is more likely among women with a previous C. trachomatis infection...
  12. doi request reprint Prospective study of human papillomavirus seropositivity and risk of nonmelanoma skin cancer
    Kristin Andersson
    Department of Medical Microbiology, Skane University Hospital, Malmo, Sweden
    Am J Epidemiol 175:685-95. 2012
    ..In summary, seropositivity for certain HPV types was associated with an increased risk for future development of SCC and BCC...
  13. doi request reprint Three novel papillomaviruses (HPV109, HPV112 and HPV114) and their presence in cutaneous and mucosal samples
    Johanna Ekström
    Department of Laboratory Medicine, Lund University, Malmo University Hospital, Entrance 78, 205 02 Malmo, Sweden
    Virology 397:331-6. 2010
    ..7% (48/2856) of the genital samples, whereas both HPV109 and 112 were rare viruses found at high viral loads only in their index samples...
  14. doi request reprint Comparison of use of vaginal HPV self-sampling and offering flexible appointments as strategies to reach long-term non-attending women in organized cervical screening
    Lotten Darlin
    Department of Obstetrics and Gynaecology, Skane University Hospital, Lund University, Lund, Sweden
    J Clin Virol 58:155-60. 2013
    ..Many cervical cancers occur among women who have not attended cervical screening. Strategies to reach non-attending women may improve the effectiveness of cervical screening programmes...
  15. pmc Cutaneous human papillomavirus 88: remarkable differences in viral load
    Johanna Kullander
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    Int J Cancer 122:477-80. 2008
    ..All these had very low viral loads (<1 copy/10(3) cells) implying extreme biological variability in viral load...
  16. ncbi request reprint Human papillomavirus 16, 18, and 33 infections and risk of prostate cancer: a Nordic nested case-control study
    Zoltan Korodi
    Department of Medical Microbiology, Lund University, MAS University Hospital, SE 20502 Malmo, Sweden
    Cancer Epidemiol Biomarkers Prev 14:2952-5. 2005
    ..Our data do not support an association between serologic markers of HPV-16, HPV-18, and HPV-33 infections and risk of prostate cancer...
  17. doi request reprint High-throughput monitoring of human papillomavirus type distribution
    Anna Söderlund-Strand
    Department of Clinical Microbiology, Skane University Hospital, Malmo, Sweden
    Cancer Epidemiol Biomarkers Prev 22:242-50. 2013
    ..Sexually active adolescents are a preferred target group for monitoring, as effects on HPV prevalence would be measurable shortly after implementation of vaccination programs...
  18. doi request reprint Pseudovirion-binding and neutralizing antibodies to cutaneous human papillomaviruses (HPV) correlated with the presence of HPV DNA in skin
    Helena Faust
    Department of Laboratory Medicine, Skane University Hospital, Lund University, Malmo, Sweden
    J Gen Virol 94:1096-103. 2013
    ..In summary, cutaneous HPVs also appear to induce a type-specific antibody response that correlates with the presence of HPV DNA and that can be detected with improved sensitivity using PsV-based serology...
  19. doi request reprint High throughput sequencing reveals diversity of Human Papillomaviruses in cutaneous lesions
    Johanna Ekström
    Division of Medical Microbiology, Department of Laboratory Medicine, Lund University, Skånes Universitetssjukhus, Malmo, Sweden
    Int J Cancer 129:2643-50. 2011
    ..In conclusion, high throughput sequencing was an effective means to identify both known and previously unknown HPV types in putatively HPV-associated lesions and has revealed an extended diversity of HPV types...
  20. doi request reprint Prospective study of Merkel cell polyomavirus and risk of Merkel cell carcinoma
    Helena Faust
    Department of Medical Microbiology, Skane University Hospital, Lund University, Malmo, Sweden
    Int J Cancer 134:844-8. 2014
    ..0, 95% CI 1.6-42.8) and for MCV neutralizing activity (OR 14.3, 95% CI 1.7-677). In conclusion, we found prospective evidence that MCV infection is associated with an increased risk for future MCC, in particular among females. ..
  21. doi request reprint Prospective study of genital human papillomaviruses and nonmelanoma skin cancer
    Kristin Andersson
    Department of Laboratory Medicine, Clinical Microbiology, Lund University, Skane University Hospital, Malmo, Sweden
    Int J Cancer 133:1840-5. 2013
    ..As only a small proportion of seropositive subjects had evidence of the corresponding HPV DNA in the tumor, most of this excess risk is likely to be due to confounders associated with genital HPV infection...
  22. pmc Interactive effect of genetic susceptibility with height, body mass index, and hormone replacement therapy on the risk of breast cancer
    Sophia Harlid
    Department of Clinical Chemistry, Lund University, Malmo, Sweden
    BMC Womens Health 12:17. 2012
    ..We have investigated potential interactions between certain known genetic and phenotypic risk factors, specifically nine single nucleotide polymorphisms (SNPs) and height, body mass index (BMI) and hormone replacement therapy (HRT)...
  23. pmc Genetic predisposition, parity, age at first childbirth and risk for breast cancer
    Salma Butt
    Department of Surgery, Skane University Hospital, Lund University, Malmo, Sweden
    BMC Res Notes 5:414. 2012
    ..The aim of the present study was to examine the interaction between these environmental factors and genetic variants on breast cancer risk...
  24. pmc The 2010 global proficiency study of human papillomavirus genotyping in vaccinology
    Carina Eklund
    WHO HPV LabNet Global Reference Laboratory, Department of Clinical and Medical Microbiology, Laboratory Medicine Skåne, and Lund University, Malmo, Sweden
    J Clin Microbiol 50:2289-98. 2012
    ..In conclusion, continued global proficiency studies will be required for establishing comparable and reliable HPV genotyping services for vaccinology worldwide...
  25. doi request reprint Staphylococcus aureus and squamous cell carcinoma of the skin
    Johanna Kullander
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    Cancer Epidemiol Biomarkers Prev 18:472-8. 2009
    ..aureus. The study design used cannot determine whether the association implies that presence of S. aureus might influence carcinogenesis or whether it may imply that SCC has an increased susceptibility to S. aureus colonization...
  26. doi request reprint Antibodies to Merkel cell polyomavirus correlate to presence of viral DNA in the skin
    Helena Faust
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    J Infect Dis 203:1096-100. 2011
    ..6-166.5]), with 97% of patients who tested positive for MCV DNA being MCV seropositive. VLP antibody levels correlated to neutralization titers (r=.72), and high antibody levels correlated to high MCV load (P<.01)...
  27. ncbi request reprint Human papillomavirus subtypes are not uncommon
    Kristina Hazard
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, S 205 02 Malmo, Sweden
    Virology 362:6-9. 2007
    ..The number of types/putative types in each genus was 54, 58 and 103. Thus, there appears to exist at least 47 different subtypes/putative subtypes of HPV and they seem to be particularly common in the genus Beta-papillomavirus...
  28. ncbi request reprint High-throughput genotyping of oncogenic human papilloma viruses with MALDI-TOF mass spectrometry
    Anna Söderlund-Strand
    WHO HPV LabNet Global Reference Laboratory and Department of Medical Microbiology, Lund University, Malmo University Hospital, Malmo, Sweden
    Clin Chem 54:86-92. 2008
    ..Use of HPV genotyping in cervical screening programs and for monitoring the effectiveness of HPV vaccination programs requires access to economical, high-throughput technology...
  29. ncbi request reprint No excess risk for colorectal cancer among subjects seropositive for the JC polyomavirus
    Annika Lundstig
    Department of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    Int J Cancer 121:1098-102. 2007
    ..1 (95% CI: 0.8-1.5). Determining seropositivity using alternative cutoffs also found no evidence of excess risk. In summary, this prospective study found no association between JCV or BKV infections and excess risk for colorectal cancer...
  30. doi request reprint Human papillomavirus typing in reporting of condyloma
    Erik Sturegard
    WHO HPV LabNet Global Reference Laboratory, Department of Clinical Microbiology, University and Regional Laboratories Region Skåne, Malmo, Sweden
    Sex Transm Dis 40:123-9. 2013
    ..If reporting could include HPV typing, the contribution by vaccine HPV types to condyloma burden could be monitored...
  31. ncbi request reprint Seroprevalence of human papillomaviruses and Chlamydia trachomatis and cervical cancer risk: nested case-control study
    Pontus Naucler
    Lund University, University Hospital at Malmö, SE 20502 Malmo, Sweden
    J Gen Virol 88:814-22. 2007
    ..trachomatis is associated with cervical cancer in prospective studies, and support the notion that HPV-16 seropositivity is strongly associated with cervical cancer...
  32. ncbi request reprint Population-based study of screening test performance indices of three human papillomavirus DNA tests
    Cecilia Wahlström
    Department of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    J Med Virol 79:1169-75. 2007
    ..0%, 92.9%, and 15.3% for Amplicor with raised cut-off, and 7.8%, 79.7%, and 16.9% for Hybrid Capture II. In conclusion, AmpliTaq GP5+/6+ PCR and Amplicor with raised cut-off value have adequate performance indices for primary screening...
  33. doi request reprint Serum antibodies to human papillomavirus (HPV) pseudovirions correlate with natural infection for 13 genital HPV types
    Helena Faust
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Jan Waldenströms gata 59, 20502 Malmo, Sweden
    J Clin Virol 56:336-41. 2013
    ....
  34. doi request reprint Metagenomic sequencing of "HPV-negative" condylomas detects novel putative HPV types
    Hanna Johansson
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, Malmo, Sweden
    Virology 440:1-7. 2013
    ..Complete genomes of Gammapillomavirus FA69 and SE87 were compiled. Metagenomic sequencing reveals that seemingly "HPV-negative" condylomas contain known and previously unknown HPV types...
  35. pmc Multiplex detection of human herpesviruses from archival specimens by using matrix-assisted laser desorption ionization-time of flight mass spectrometry
    Malin I L Sjöholm
    The Swedish National Biobanking Program, Lund University, Malmo University Hospital, S 205 02, Malmo, Sweden
    J Clin Microbiol 46:540-5. 2008
    ..6% (kappa = 0.90). In summary, the MALDI-TOF MS method is well suited for large-scale detection of all known human herpesviruses in a wide variety of archival biological specimens...
  36. doi request reprint The Bcl-xL inhibitor of apoptosis is preferentially expressed in cutaneous squamous cell carcinoma compared with that in keratoacanthoma
    Natasa Vasiljevic
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    Int J Cancer 124:2361-6. 2009
    ..001). The lower expression of the antiapoptotic protein Bcl-xL in KA is consistent with a possible role of apoptosis in the regression of KA...
  37. doi request reprint Strengthening prevention programs to eliminate cervical cancer in the Nordic countries
    Lena Dillner
    WHO Global Reference Laboratory for HPV Diagnosis and Control, Department of Clinical Microbiology, University Hospital, Malmo, Sweden
    Acta Obstet Gynecol Scand 87:489-98. 2008
    ..The same principles as set up for organized programs and new HPV technologies may apply for screening and vaccination as key tools to eliminate cervical cancer in the Nordic countries and globally...
  38. ncbi request reprint Subtype HPV38b[FA125] demonstrates heterogeneity of human papillomavirus type 38
    Kristina Hazard
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    Int J Cancer 119:1073-7. 2006
    ..In summary, we found that HPV38 is heterogeneous and is one of so far only few HPVs that contain subtypes. The heterogeneity needs to be considered in studies of the biology of this virus...
  39. doi request reprint Prevalence of antibodies against Kaposi's sarcoma associated herpes virus (KSHV) complement inhibitory protein (KCP) in KSHV-related diseases and their correlation with clinical parameters
    Marcin Okroj
    Department of Laboratory Medicine Malmö, Lund University, 20502 Malmo, Sweden
    Vaccine 29:1129-34. 2011
    ..This fact combined with results of statistical analysis suggests that KCP inactivation by specific antibodies may influence progression of classical KS...
  40. doi request reprint Randomized healthservices study of human papillomavirus-based management of low-grade cytological abnormalities
    Lena Dillner
    Department of Clinical Microbiology, WHO HPVLabNet Global Reference laboratory, Lund University, Malmo University Hospital, SE 20502 Malmo, Sweden
    Int J Cancer 129:151-9. 2011
    ..HPV triaging was cost-effective only above 35 years of age. In conclusion, a real-life randomized healthservices study of HPV triaging of women with ASCUS/CINI demonstrated similar detection of CINII+ as colposcopy of all women...
  41. pmc Modified general primer PCR system for sensitive detection of multiple types of oncogenic human papillomavirus
    Anna Söderlund-Strand
    WHO HPV LabNet Global Reference Laboratory, Department of Clinical Microbiology, Lund University, Malmo University Hospital, SE 20502 Malmo, Sweden
    J Clin Microbiol 47:541-6. 2009
    ..In summary, the MGP system primers allow a more sensitive amplification of most of the HPV types that are established as oncogenic and had an improved ability to detect multiple concomitant HPV infections...
  42. pmc Comparison between the Hybrid Capture II test and a PCR-based human papillomavirus detection method for diagnosis and posttreatment follow-up of cervical intraepithelial neoplasia
    Anna Söderlund-Strand
    Department of Medical Microbiology, Lund University, University Hospital of Malmo, SE 205 02 Malmo, Sweden
    J Clin Microbiol 43:3260-6. 2005
    ..5% for PCR and 85.4% for HCII. In conclusion, the sensitivities of both PCR-EIA and HCII are high and almost equal, suggesting that both methods are suitable as tools for detection and posttreatment follow-up of CIN II-III...
  43. ncbi request reprint Characterization of two novel cutaneous human papillomaviruses, HPV93 and HPV96
    Natasa Vasiljevic
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Sweden
    J Gen Virol 88:1479-83. 2007
    ..The E7 proteins of HPV92, 93 and 96 were found to bind the retinoblastoma protein (pRb). These results suggest a possible role for these HPV types in skin carcinogenesis that deserves further study...
  44. doi request reprint Absence of Epstein-Barr and cytomegalovirus infection in neuroblastoma cells by standard detection methodologies
    Daniel Sehic
    Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden
    Pediatr Blood Cancer 60:E91-3. 2013
    ..These standard methods did not detect infection by EBV or HCMV in NB cells in any tumor, while occasional immune cells were positive for EBV RNA or HCMV protein in four cases...
  45. ncbi request reprint Decline of the new Swedish variant of Chlamydia trachomatis after introduction of appropriate testing
    Kenneth Persson
    Department of Laboratory Medicine, Medical Microbiology, University Hospital in Malmo, Malmo SE 205 02, Sweden
    Sex Transm Infect 88:451-5. 2012
    ..The longitudinal epidemiological development of the new variant of Chlamydia trachomatis was studied after appropriate testing procedures had been introduced when the strain was detected in 2006...
  46. doi request reprint International collaborative proficiency study of Human Papillomavirus type 16 serology
    Carina Eklund
    WHO HPV LabNet Global Reference Laboratory, Department of Clinical and Medical Microbiology, Skåne and Lund University, Malmo, Sweden
    Vaccine 30:294-9. 2012
    ....
  47. ncbi request reprint Cutaneous human papillomaviruses persist on healthy skin
    Kristina Hazard
    Department of Laboratory Medicine, Division of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    J Invest Dermatol 127:116-9. 2007
    ..Persistence was not significantly associated with age, sex, immunosuppressive treatment, history of warts, or genus of HPV. We conclude that cutaneous HPV infections commonly persist over several years on healthy skin...
  48. ncbi request reprint No detection of SV40 DNA in mesothelioma tissues from a high incidence area in Sweden
    Annika Lundstig
    Department of Medical Microbiology, Malmo University Hospital, Lund University, 20502 Malmo, Sweden
    Anticancer Res 27:4159-61. 2007
    ..All the samples were also tested for amplifiability using a real-time PCR for the beta-globin gene. Eighteen tumors were amplifiable, but none contained SV40 DNA. The results do not support an association between mesothelioma and SV40...
  49. ncbi request reprint Antibodies against Kaposi sarcoma-associated herpes virus (KSHV) complement control protein (KCP) in infected individuals
    Marcin Okroj
    Department of Laboratory Medicine, Lund University, University Hospital Malmo, S 205 02 Malmo, Sweden
    Vaccine 25:8102-9. 2007
    ..Furthermore, pre-incubation of KCP-expressing CHO cells with patient sera containing anti-KCP antibodies resulted in an increased complement deposition when incubated with human serum...
  50. doi request reprint Differences in transcriptional activity of cutaneous human papillomaviruses
    Natasa Vasiljevic
    Department of Medical Microbiology, Lund University, Malmo University Hospital, Malmo, Sweden
    Virus Res 137:213-9. 2008
    ..As there are variable UV-B responses among the HPV types, further studies of interactions between UV-B and HPV need to consider the HPV type...
  51. pmc High prevalence of cutaneous human papillomavirus DNA on the top of skin tumors but not in "Stripped" biopsies from the same tumors
    Ola Forslund
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    J Invest Dermatol 123:388-94. 2004
    ..HPV DNA is common in superficial layers of lesions, but is not necessarily present throughout tumors...
  52. doi request reprint The interface of population-based cancer registries and biobanks in etiological and clinical research--current and future perspectives
    Kristin Andersson
    Lund University, Malmo, Sweden
    Acta Oncol 49:1227-34. 2010
    ..Recent networking projects have brought these infrastructures together to promote the combined use of cancer registries and biobanks in cancer research...
  53. ncbi request reprint Serological diagnosis of human polyomavirus infection
    Annika Lundstig
    Lund University, Malm University Hospital, Sweden
    Adv Exp Med Biol 577:96-101. 2006
    ..SV40-specific seropositivity also increased with increasing age of children, reaching 14% seroprevalence among children 7-9 years of age, but had limited stability over time in serial samples...
  54. ncbi request reprint Maternal human polyomavirus infection and risk of neuroblastoma in the child
    Annika Stolt
    Department of Medical Microbiology, Malmo University Hospital, Malmo, Sweden
    Int J Cancer 113:393-6. 2005
    ..In summary, a comprehensive cohort using both serology and polyomavirus DNA detection found no evidence for association between BKV or JCV polyomaviruses and neuroblastoma...
  55. ncbi request reprint No serological evidence of association between prostate cancer and infection with herpes simplex virus type 2 or human herpesvirus type 8: a nested case-control study
    Zoltan Korodi
    Department of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    J Infect Dis 191:2008-11. 2005
    ..Neither HSV-2 infection (odds ratio [OR], 0.93 [95% confidence interval {CI}, 0.44-1.96]) nor HHV-8 infection (OR, 0.74 [95% CI, 0.19-2.88]) was associated with prostate cancer...
  56. pmc Global proficiency study of human papillomavirus genotyping
    Carina Eklund
    WHO HPV LabNet Global Reference Laboratory, Department of Clinical and Medical Microbiology, Laboratory Medicine Skåne, Lund University, Malmo, Sweden
    J Clin Microbiol 48:4147-55. 2010
    ....
  57. doi request reprint Seroconversion to islet autoantibodies between early pregnancy and delivery in non-diabetic mothers
    Sabina Resic Lindehammer
    Department of Clinical Sciences, Diabetes and Celiac Disease Unit, Lund University CRC, Skåne University Hospital SUS, 20502 Malmo, Sweden
    J Reprod Immunol 88:72-9. 2011
    ....
  58. doi request reprint Global improvement in genotyping of human papillomavirus DNA: the 2011 HPV LabNet International Proficiency Study
    Carina Eklund
    WHO HPV LabNet Global Reference Laboratory, Departments of Clinical and Medical Microbiology, Laboratory Medicine Skåne and Lund University, Malmo, Sweden
    J Clin Microbiol 52:449-59. 2014
    ..In conclusion, a continuing global proficiency program has documented worldwide improvement in the comparability and reliability of HPV genotyping assay performances...
  59. doi request reprint Global Improvement in Genotyping of Human Papillomavirus DNA: the 2011 HPV LabNet International Proficiency Study
    Carina Eklund
    WHO HPV LabNet Global Reference Laboratory, Departments of Clinical and Medical Microbiology, Laboratory Medicine Skåne and Lund University, Malmo, Sweden
    J Clin Microbiol 52:449-59. 2014
    ..In conclusion, a continuing global proficiency program has documented worldwide improvement in the comparability and reliability of HPV genotyping assay performances. ..
  60. doi request reprint Vaginal self-sampling without preservative for human papillomavirus testing shows good sensitivity
    Lotten Darlin
    Department of Obstetrics and Gynaecology, Skane University Hospital, Lund University, Sweden
    J Clin Virol 56:52-6. 2013
    ..Self-sampling (SS) for HPV is effective for increasing coverage in screening programs, but requires expensive commercial sampling kits...
  61. doi request reprint Validation of multiplexed human papillomavirus serology using pseudovirions bound to heparin-coated beads
    Helena Faust
    Department of Medical Microbiology, Malmo University Hospital, Lund University, Malmo, Sweden
    J Gen Virol 91:1840-8. 2010
    ..In summary, multiplexed HPV serology using mammalian-derived PsVs selected for native conformation by binding to heparin-coated beads was validated as a high-throughput HPV serological method for most of the analysed HPV types...
  62. doi request reprint Mutations in human papillomavirus type 16 L1 hypervariable surface-exposed loops affect L2 binding and DNA encapsidation
    Helena Faust
    Department of Laboratory Medicine, Medical Microbiology, Skane University Hospital, Lund University, Jan Waldenströms gata 59, 20502, Malmo, Sweden
    J Gen Virol 94:1841-9. 2013
    ..Ability to induce cross-neutralizing antibodies and to encapsidate pseudogenomes were completely abrogated. In summary, the surface-exposed L1 loops are important for the function of the HPV particle. ..
  63. ncbi request reprint Comparison of archival plasma and formalin-fixed paraffin-embedded tissue for genotyping in hepatocellular carcinoma
    Malin I L Sjöholm
    Department of Clinical Chemistry, University Hospital MAS, Entrance 71, 205 02 Malmo, Sweden
    Cancer Epidemiol Biomarkers Prev 14:251-5. 2005
    ..In summary, archival plasma was found to be an adequate source of efficiently amplifiable DNA. MDA on plasma samples allows analysis of multiple genotypes in epidemiologic studies...
  64. ncbi request reprint [Testing HPV vaccine is an ethical dilemma. Can we afford not to offer vaccination against an infection which is a cause of cancer?]
    Joakim Dillner
    Avdelningen för medicinsk mikrobiologi, Lunds universitet, Universitetssjukhuset MAS, Malmo
    Lakartidningen 100:3390-1. 2003
  65. ncbi request reprint Can genital-tract human papillomavirus infection and cervical cancer be prevented with a vaccine?
    Joakim Dillner
    Division of Laboratory Medicine, Department of Medical Microbiology, University Hospital at Malmö, Lund University, S 20502 Malmo, Sweden
    Expert Rev Mol Med 6:1-21. 2004
    ..It then summarises studies examining the use of vaccines to prevent HPV infection in animals and humans, and, finally, discusses some of the unanswered issues surrounding vaccine development against HPV infection and cervical cancer...
  66. ncbi request reprint [The survey of Danish biobanks suggests a "drop-out" registry]
    Joakim Dillner
    Avdelningen för medicinsk virologi, Universitetssjukhuset MAS, Malmo
    Lakartidningen 99:4384-5. 2002
  67. ncbi request reprint Mapping of human serum-reactive epitopes in virus-like particles of human papillomavirus types 16 and 11
    Xiaohong Wang
    Department of Medical Microbiology, MAS University Hospital, S 20502, Malmo, Sweden
    Virology 311:213-21. 2003
    ..For both HPV16 and HPV11, the major serologic reactivity was directed toward the C-terminal part of the protein and the H16.V5 binding site appeared to be a major serologically reactive epitope of HPV16...
  68. ncbi request reprint Assessing quality and functionality of DNA from fresh and archival dried blood spots and recommendations for quality control guidelines
    Malin Ida Linnea Sjöholm
    The Swedish National Biobanking Program, Lund University, Malmo University Hospital, Malmo, Sweden
    Clin Chem 53:1401-7. 2007
    ..Although many countries have established population-based DBS biobanks from neonatal screening programs, the quality and usefulness of DNA from DBS have not been extensively assessed...
  69. ncbi request reprint Population-based type-specific prevalence of high-risk human papillomavirus infection in middle-aged Swedish women
    Ola Forslund
    Department of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
    J Med Virol 66:535-41. 2002
    ..The type-specific HPV prevalence found support in previous modeling studies suggesting that HPV screening may be a favorable cervical screening strategy...
  70. ncbi request reprint High levels of circulating testosterone are not associated with increased prostate cancer risk: a pooled prospective study
    Par Stattin
    Department of Urology, Umea University Hospital, Umea, Sweden
    Int J Cancer 108:418-24. 2004
    ..bottom quintile of 0.82 (95% CI = 0.60-1.14; p(trend) = 0.44). No support was found for the hypothesis that high levels of circulating androgens within a physiologic range stimulate development and growth of prostate cancer...
  71. ncbi request reprint Virologic versus cytologic triage of women with equivocal Pap smears: a meta-analysis of the accuracy to detect high-grade intraepithelial neoplasia
    Marc Arbyn
    European Network for Cervical Cancer Screening and Unit for Evaluation of Cancer Screening Programmes, Scientific Institute of Public Health, Brussels, Belgium
    J Natl Cancer Inst 96:280-93. 2004
    ..We performed a meta-analysis to assess the accuracy of human papillomavirus (HPV) DNA testing as an alternative to repeat cytology in women who had equivocal results on a previous Pap smear...
  72. ncbi request reprint Prostate cancer risk and serologic evidence of human papilloma virus infection: a population-based case-control study
    Hans Olov Adami
    Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
    Cancer Epidemiol Biomarkers Prev 12:872-5. 2003
    ..Additional studies of the relationship between prostate cancer and other HPV types, notably HPV 33, could be helpful for clarifying the possible role of sexual risk factors...
  73. ncbi request reprint Maternal herpesvirus infections and risk of acute lymphoblastic leukemia in the offspring
    Matti Lehtinen
    Department of Infectious Disease Epidemiology, National Public Health Institute, Helsinki, Finland
    Am J Epidemiol 158:207-13. 2003
    ..9, 95% confidence interval: 1.5, 5.8). Results indicate that reactivation of maternal EBV infection is probably associated with childhood ALL...
  74. ncbi request reprint Time trends in incidence and prevalence of human papillomavirus type 6, 11 and 16 infections in Finland
    Päivi Laukkanen
    National Public Health Institute, Helsinki and Oulu, Mannerheimintie 166, 00300 Helsinki, Finland
    J Gen Virol 84:2105-9. 2003
    ..Epidemic spread of the oncogenic HPV-16, but not the non-oncogenic HPV-types, throughout the 1980s and 1990s preceded an increase in the incidence of cervical carcinoma in fertile-aged Finnish women...
  75. ncbi request reprint Moderate variation of the oncogenic potential among high-risk human papillomavirus types in gynecologic patients with cervical abnormalities
    Krisztina Szoke
    Department of Medical Microbiology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    J Med Virol 71:585-92. 2003
    ..The risk ratios between the groups of high-risk types were found to differ at most by a factor of 2.98 (corrected P value: 0.007) indicating that the oncogenic potential varies moderately within the high-risk group of HPVs...
  76. ncbi request reprint Evaluation of antibody response to human papillomavirus early proteins in women in whom cervical cancer developed 1 to 20 years later
    Matti Lehtinen
    Department of Infectious Disease Epidemiology and Microbiology, National Public Health Institute, Helsinki, Finland
    Am J Obstet Gynecol 188:49-55. 2003
    ..Our purpose was to evaluate whether antibodies to HPV16 and HPV18 E6 and E7 proteins are useful for early diagnosis of cervical cancer by measuring the antibody response in women in whom cervical cancer later developed...
  77. doi request reprint Screening-preventable cervical cancer risks: evidence from a nationwide audit in Sweden
    Bengt Andrae
    Department of Obstetrics and Gynecology, Gavle Hospital, S 801 87 Gävle, Sweden
    J Natl Cancer Inst 100:622-9. 2008
    ..Routine and comprehensive audits have been proposed as an ethically required component of screening. We performed a nationwide audit of the effectiveness of the Swedish cervical cancer screening program...
  78. ncbi request reprint Rate of human papillomavirus clearance after treatment of cervical intraepithelial neoplasia
    Kristina Elfgren
    Department of Obstetrics and Gynecology, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
    Obstet Gynecol 100:965-71. 2002
    ..To investigate the rate of clearance of human papillomavirus (HPV) infection after surgical treatment for cervical intraepithelial neoplasia (CIN)...
  79. ncbi request reprint Herpes simplex virus and risk of cervical cancer: a longitudinal, nested case-control study in the nordic countries
    Matti Lehtinen
    School of Public Health, University of Tampere, Finland
    Am J Epidemiol 156:687-92. 2002
    ..6, 1.7) and 0.7 (95% CI: 0.3, 1.6), respectively, for HPV seropositives. In the meta-analysis, the relative risk for HSV-2 was 0.9 (95% CI: 0.6, 1.3). In both sets of data, HSV-2 did not play a role in cervical carcinogenesis...
  80. ncbi request reprint A population-based prospective study of Chlamydia trachomatis infection and cervical carcinoma
    Keng Ling Wallin
    Department of Molecular Medicine, Karolinska Institute, Stockholm, Sweden
    Int J Cancer 101:371-4. 2002
    ..trachomatis in both the prediagnostic smear and in the subsequent cervical cancer. In conclusion, a prior cervical C. trachomatis infection was associated with an increased risk for development of invasive cervical cancer...
  81. ncbi request reprint Evaluation of antibodies to human papillomavirus as prognostic markers in cervical cancer patients
    Ilvars Silins
    Department of Medical Microbiology, MAS University Hospital, S 20502 Malmo, Sweden
    Gynecol Oncol 85:333-8. 2002
    ..We wished to evaluate whether the presence of antibodies to HPV or to the HPV oncoproteins E6 and E7 or type of HPV DNA is related to prognosis among cervical cancer patients...
  82. ncbi request reprint Circulating enterolactone and prostate cancer risk: a Nordic nested case-control study
    Par Stattin
    Department of Urology, Umea University Hospital, Umea, Sweden
    Int J Cancer 99:124-9. 2002
    ..21 (95% CI = 0.91-1.60), 1.02 (95% CI = 0.59-1.76) and 0.87 (95% CI = 0.45-1.67), respectively. No support for the hypothesis that high circulating enterolactone is protective against prostate cancer was found...
  83. ncbi request reprint Clustering of seropositivities for sexually transmitted infections
    Ilvars Silins
    Microbiology and Tumor Biology Center, Karolinska Institute, Stockholm, Sweden
    Sex Transm Dis 29:207-11. 2002
    ....
  84. ncbi request reprint Use of human papillomavirus DNA testing to compare equivocal cervical cytologic interpretations in the United States, Scandinavia, and the United Kingdom
    David R Scott
    Kaiser Permanente Department of Pathology, Portland, Oregon, USA
    Cancer 96:14-20. 2002
    ..Because international differences may be particularly marked, international comparisons of emerging data will require clear translations of "equivocal" and similar terms...
  85. ncbi request reprint A population-based study of cervical carcinoma and HPV infection in Latvia
    Ilvars Silins
    Oncology Center of Latvia, Riga
    Gynecol Oncol 93:484-92. 2004
    ..We wished to quantify the population-based importance of cervical carcinoma risk factors in Latvia...
  86. ncbi request reprint Re: Have we resolved how to triage equivocal cervical cytology?
    Marc Arbyn
    J Natl Cancer Inst 96:1401-2; author reply 1402. 2004
  87. ncbi request reprint Genetic polymorphism of chemokine receptors CCR2 and CCR5 in Swedish cervical cancer patients
    Biying Zheng
    Department of Molecular Medicine and Surgery, Karolinska Institute, Center for Molecular Medicine and Karolinska University Hospital Solna, Stockholm, Sweden
    Anticancer Res 26:3669-74. 2006
    ..045) compare to HPV negative group. The delta-32 mutation on the CCR locus is imperceptibly associated with increased risk of HPV infection. In total, cervical neoplasia was not associated with genetic polymorphism of CCR2 and CCR5...
  88. ncbi request reprint Epidemiology of Kaposi's Sarcoma herpesvirus (HHV8) in Västerbotten County, Sweden
    Rosamaria Tedeschi
    Microbiology Immunology and Virology Department, Centro di Riferimento Oncologico, IRCCS, Aviano, Italy
    J Med Virol 78:372-8. 2006
    ..25-0.77 and OR: 0.50, 95% CI: 0.26-0.95, respectively). In summary, HHV8 has an intermediate high and stable seroprevalence rate in Northern Sweden, but environmental determinants that can explain the viral distribution were not found...
  89. ncbi request reprint A report on the current status of European research on the use of human papillomavirus testing for primary cervical cancer screening
    Philip Davies
    European Cervical Cancer Association, 68 cours Albert Thomas, Lyon, France
    Int J Cancer 118:791-6. 2006
    ..Our study reviews the randomized controlled trials that are currently being conducted in Europe to establish the performance of HPV testing as a primary cervical cancer screening test...
  90. ncbi request reprint Nordic biological specimen banks as basis for studies of cancer causes and control--more than 2 million sample donors, 25 million person years and 100,000 prospective cancers
    Eero Pukkala
    Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland
    Acta Oncol 46:286-307. 2007
    ..The present paper summarizes optimal study designs of biobank-based studies of cancer...
  91. ncbi request reprint Alcohol, smoking and human papillomavirus in laryngeal carcinoma: a Nordic prospective multicenter study
    Walter J Koskinen
    Department of Virology, Haartman Institute, University of Helsinki, Haartmaninkatu 3, P O Box 21, 00014 Helsinki, Finland
    J Cancer Res Clin Oncol 133:673-8. 2007
    ..Moreover risk factors such as smoking, alcohol abuse, chronic laryngitis and gastroesophageal reflux disease (GERD) were evaluated..
  92. ncbi request reprint Colposcopic and histopathologic evaluation of women participating in population-based screening for human papillomavirus deoxyribonucleic acid persistence
    Kristina Elfgren
    Department of Obstetrics and Gynecology, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    Am J Obstet Gynecol 193:650-7. 2005
    ..Evaluation of colposcopic and histopathological findings in women screened for cervical human papillomavirus deoxyribonucleic acid persistence...
  93. ncbi request reprint [Cervix cancer screening can be cost-effective. Combination of vaginal smears and the HPV test should be even more beneficial]
    Peter Bistoletti
    Centrum för utvärdering av medicinsk teknologi CMT, Linkopings Universitet, och kvinnokliniken, Nyköpings
    Lakartidningen 102:1874-6, 1878-9. 2005
  94. doi request reprint A randomized trial of basing treatment on human papillomavirus and/or cytology results in low-grade cervical lesion triage
    Pontus Bjerre
    Department of Obstetrics and Gynecology, Central Hospital, Karlstad, Sweden
    Am J Obstet Gynecol 199:24.e1-7. 2008
    ..This study was undertaken to compare management algorithms that base treatment with loop electrosurgical excision procedure on human papillomavirus and/or repeat Papanicolaou test smear results...
  95. ncbi request reprint Chapter 9: Clinical applications of HPV testing: a summary of meta-analyses
    Marc Arbyn
    Unit of Cancer Epidemiology, Scientific Institute of Public Health, J Wytsmanstreet 14, Brussels, Belgium
    Vaccine 24:S3/78-89. 2006
    ..More than ever, clinicians need regularly updated reviews given the continuously increasing amount of new information regarding innovative cervical cancer prevention methods...
  96. pmc In vivo and in vitro intragenomic rearrangement of TT viruses
    Ludmila Leppik
    Division for the Characterization of Tumor Viruses, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 242, 69120 Heidelberg, Germany
    J Virol 81:9346-56. 2007
    ..These data demonstrate new features of TT viruses suggesting possible similarities to plant viruses of the family Geminiviridae, as well as raise questions about the documented plurality and diversity of anelloviruses...
  97. ncbi request reprint Cost-effectiveness of primary cytology and HPV DNA cervical screening
    Peter Bistoletti
    Department of Obstetrics and Gynecology, Nacka Hospital, Nacka, Sweden
    Int J Cancer 122:372-6. 2008
    ..If screening intervals are increased to at least 9 years, combined cytology and HPV DNA screening appeared to be still more effective and less costly...
  98. ncbi request reprint Evaluation of cost-precision rations of different strategies for ELISA measurement of serum antibody levels
    Katarzyna Grabowska
    Swedish Institute for Infectious Diseases Control, Solna, Sweden
    J Immunol Methods 271:1-15. 2002
    ..Strategies with optimal cost-precision ratios were designed. The novel calculation method termed wPLL was preferable...
  99. ncbi request reprint Chapter 23: International Standard reagents for harmonization of HPV serology and DNA assays--an update
    Sonia R Pagliusi
    Department of Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland
    Vaccine 24:S3/193-200. 2006
    ..It is hoped that the establishment of International Units and International Standards for HPV antibody and DNA analysis will be pursued with high priority...
  100. ncbi request reprint Toward "serolomics": papillomavirus serology is taking a technologic lead in high-throughput multiplexed antibody analysis
    Joakim Dillner
    Clin Chem 51:1768-9. 2005
  101. ncbi request reprint Results of the first WHO international collaborative study on the standardization of the detection of antibodies to human papillomaviruses
    Morag Ferguson
    Division of Virology, National Institute for Biological Standards and Control, South Mimms, United Kingdom
    Int J Cancer 118:1508-14. 2006
    ..Establishment of an International Standard for antibodies to HPV 16 would therefore facilitate the comparison of HPV antibody measurements between laboratories and assays...