Research Topics
| E DegermanSummaryAffiliation: Lund University Country: Sweden Publications
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Detail Information
Publications
Phosphorylation and activation of hormone-sensitive adipocyte phosphodiesterase type 3BE Degerman
Section for Molecular Signalling, Lund University, Lund, Sweden
Methods 14:43-53. 1998..In the review we describe methods and strategies used in the authors' laboratories to study phosphorylation and activation of PDE3B in adipocytes and in vitro...
Insulin-induced translocation of protein kinase B to the plasma membrane in rat adipocytesO Göransson
Department of Cell and Molecular Biology, Lund University, Sweden
Biochem Biophys Res Commun 246:249-54. 1998..This translocation was potentiated by the tyrosine phosphatase inhibitor vanadate. Subcellular localization studies revealed that PKB translocated to the plasma membrane...
Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vitroM W Anthonsen
Department of Cell and Molecular Biology, Section for Molecular Signaling, Lund University, S 221 00 Lund, Sweden
J Biol Chem 273:215-21. 1998....
Identification of the site in the cGMP-inhibited phosphodiesterase phosphorylated in adipocytes in response to insulin and isoproterenolT Rahn
Department of Cell and Molecular Biology, Lund University, Sweden
J Biol Chem 271:11575-80. 1996..and Manganiello, V.C. (1991) J. Biol. Chem. 266, 13385-13390) is proposed to reflect cross-talk between their respective signal transduction pathways at the level of the cGI PDE serine protein kinase or upstream regulatory component(s)...
Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cellsH Mulder
Department of Cell and Molecular Biology, Lund University, Sweden
Diabetes 48:228-32. 1999..g., long-chain acyl-CoA and diacylglycerol...
Regulation of protein kinase B in rat adipocytes by insulin, vanadate, and peroxovanadate. Membrane translocation in response to peroxovanadateJ Wijkander
Section for Molecular Signaling, Department of Cell and Molecular Biology, Lund University, S 221 00 Lund, Sweden jonny
J Biol Chem 272:21520-6. 1997..The translocation was prevented by wortmannin, suggesting that PI 3-kinase and/or the 3-phosphorylated phosphoinositides generated by PI 3-kinase are indeed involved in the membrane targeting of PKB...
Down-regulation of cyclic-nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes induced by tumour necrosis factor alpha and cAMPT Rahn Landstrom
Section for Molecular Signalling, Department of Cell and Molecular Biology, P O Box 94, Lund University, S 221 00 Lund, Sweden
Biochem J 346:337-43. 2000..These results, which suggest that PDE3B is a novel target for long-term regulation by TNF-alpha and cAMP, could contribute to the understanding of the mechanisms of insulin resistance...
Expression and characterization of deletion recombinants of two cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE-3)R He
Department of Cellular and Molecular Biology, Lund University, Sweden
Cell Biochem Biophys 29:89-111. 1998....
