Maria Alvarado-Kristensson

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. pmc Nuclear localization of γ-tubulin affects E2F transcriptional activity and S-phase progression
    Greta Höög
    Center for Molecular Pathology, Department of Laboratory Medicine, Lund University, Skane University Hospital, Malmo, Sweden
    FASEB J 25:3815-27. 2011
  2. pmc Tumors with nonfunctional retinoblastoma protein are killed by reduced γ-tubulin levels
    Asa Ehlén
    Center for Molecular Pathology, Department of Laboratory Medicine, Lund University, Skane University Hospital, SE 205 02 Malmo, Sweden
    J Biol Chem 287:17241-7. 2012
  3. ncbi request reprint SADB phosphorylation of gamma-tubulin regulates centrosome duplication
    Maria Alvarado-Kristensson
    Department of Immunology and Oncology, Centro Nacional de Biotecnologia CSIC, Madrid, Spain
    Nat Cell Biol 11:1081-92. 2009
  4. pmc p38-MAPK signals survival by phosphorylation of caspase-8 and caspase-3 in human neutrophils
    Maria Alvarado-Kristensson
    Division of Experimental Pathology, Lund University, U MAS, Entrance 78, Floor 3, SE 205 02 Malmo, Sweden
    J Exp Med 199:449-58. 2004
  5. pmc RBM3-Regulated Genes Promote DNA Integrity and Affect Clinical Outcome in Epithelial Ovarian Cancer
    Osa Ehlén
    Center for Molecular Pathology, Department of Laboratory Medicine, Lund University, Skane University Hospital, Malmo, Sweden
    Transl Oncol 4:212-21. 2011
  6. pmc Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer
    Asa Ehlén
    Center for Molecular Pathology, Department of Laboratory Medicine, Lund University, Skane University Hospital, Malmo, Sweden
    J Transl Med 8:78. 2010
  7. ncbi request reprint The Nuclear Localization of γ-Tubulin Is Regulated by SadB-mediated Phosphorylation
    Greta Eklund
    From the Division of Molecular Pathology, Department of Laboratory Medicine, Lund University, Skane University Hospital, SE 20502 Malmo, Sweden
    J Biol Chem 289:21360-73. 2014
  8. ncbi request reprint Protein phosphatase 2A regulates apoptosis in neutrophils by dephosphorylating both p38 MAPK and its substrate caspase 3
    Maria Alvarado-Kristensson
    Experimental Pathology, Department of Laboratory Medicine, Lund University, Malmo University Hospital, Entrance 78, 3rd Fl, SE 205 02 Malmo, Sweden
    J Biol Chem 280:6238-44. 2005
  9. ncbi request reprint PTEN regulation, a novel function for the p85 subunit of phosphoinositide 3-kinase
    Domingo F Barber
    Department of Immunology and Oncology, Centro Nacional de Biotecnología Consejo Superiod de Investigaciones Científicas, Universidad Autonoma de Madrid, Cantoblanco, Madrid E 28049, Spain
    Sci STKE 2006:pe49. 2006

Collaborators

Detail Information

Publications9

  1. pmc Nuclear localization of γ-tubulin affects E2F transcriptional activity and S-phase progression
    Greta Höög
    Center for Molecular Pathology, Department of Laboratory Medicine, Lund University, Skane University Hospital, Malmo, Sweden
    FASEB J 25:3815-27. 2011
    ..Thus, we report a novel mechanism regulating the activity of E2Fs, which can help explain how these proteins affect cell cycle progression in mammalian cells...
  2. pmc Tumors with nonfunctional retinoblastoma protein are killed by reduced γ-tubulin levels
    Asa Ehlén
    Center for Molecular Pathology, Department of Laboratory Medicine, Lund University, Skane University Hospital, SE 205 02 Malmo, Sweden
    J Biol Chem 287:17241-7. 2012
    ..Thus, the RB1/γ-tubulin signal network can be considered as a new target for cancer treatment...
  3. ncbi request reprint SADB phosphorylation of gamma-tubulin regulates centrosome duplication
    Maria Alvarado-Kristensson
    Department of Immunology and Oncology, Centro Nacional de Biotecnologia CSIC, Madrid, Spain
    Nat Cell Biol 11:1081-92. 2009
    ..We propose that SADB kinase activity controls centrosome homeostasis by regulating phosphorylation of gamma-tubulin...
  4. pmc p38-MAPK signals survival by phosphorylation of caspase-8 and caspase-3 in human neutrophils
    Maria Alvarado-Kristensson
    Division of Experimental Pathology, Lund University, U MAS, Entrance 78, Floor 3, SE 205 02 Malmo, Sweden
    J Exp Med 199:449-58. 2004
    ..Consequently, p38-MAPK can directly phosphorylate and inhibit the activities of caspase-8 and caspase-3 and thereby hinder neutrophil apoptosis, and, in so doing, regulate the inflammatory response...
  5. pmc RBM3-Regulated Genes Promote DNA Integrity and Affect Clinical Outcome in Epithelial Ovarian Cancer
    Osa Ehlén
    Center for Molecular Pathology, Department of Laboratory Medicine, Lund University, Skane University Hospital, Malmo, Sweden
    Transl Oncol 4:212-21. 2011
    ..Furthermore, it is demonstrated that Chk1, Chk2, and MCM3 are poor prognostic markers in EOC...
  6. pmc Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer
    Asa Ehlén
    Center for Molecular Pathology, Department of Laboratory Medicine, Lund University, Skane University Hospital, Malmo, Sweden
    J Transl Med 8:78. 2010
    ..The aim of this study was to examine the prognostic value of RBM3 mRNA and protein expression in epithelial ovarian cancer (EOC) and the cisplatin response upon RBM3 depletion in a cisplatin-sensitive ovarian cancer cell line...
  7. ncbi request reprint The Nuclear Localization of γ-Tubulin Is Regulated by SadB-mediated Phosphorylation
    Greta Eklund
    From the Division of Molecular Pathology, Department of Laboratory Medicine, Lund University, Skane University Hospital, SE 20502 Malmo, Sweden
    J Biol Chem 289:21360-73. 2014
    ..Our results demonstrate that SadB kinases regulate the cellular localization of γ-tubulin and thereby control S-phase progression. ..
  8. ncbi request reprint Protein phosphatase 2A regulates apoptosis in neutrophils by dephosphorylating both p38 MAPK and its substrate caspase 3
    Maria Alvarado-Kristensson
    Experimental Pathology, Department of Laboratory Medicine, Lund University, Malmo University Hospital, Entrance 78, 3rd Fl, SE 205 02 Malmo, Sweden
    J Biol Chem 280:6238-44. 2005
    ..These findings indicate that PP2A plays a pivotal dual role in the induction of neutrophil apoptosis and therefore also in the resolution of inflammation...
  9. ncbi request reprint PTEN regulation, a novel function for the p85 subunit of phosphoinositide 3-kinase
    Domingo F Barber
    Department of Immunology and Oncology, Centro Nacional de Biotecnología Consejo Superiod de Investigaciones Científicas, Universidad Autonoma de Madrid, Cantoblanco, Madrid E 28049, Spain
    Sci STKE 2006:pe49. 2006
    ....