W W Agace

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. pmc Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing
    Bengt Johansson-Lindbom
    Immunology Section, Lund University, BMC I 13, 221 84 Lund, Sweden
    J Exp Med 202:1063-73. 2005
  2. ncbi request reprint Human intestinal lamina propria and intraepithelial lymphocytes express receptors specific for chemokines induced by inflammation
    W W Agace
    Division of Rheumatology, Immunology, and Allergy, Brigham and Women s Hospital and Harvard Medical School, Boston, USA
    Eur J Immunol 30:819-26. 2000
  3. ncbi request reprint Constitutive expression of stromal derived factor-1 by mucosal epithelia and its role in HIV transmission and propagation
    W W Agace
    Division of Rheumatology, Immunology and Allergy, Brigham and Womens Hospital, Harvard Medical School, Boston 02115, USA
    Curr Biol 10:325-8. 2000
  4. ncbi request reprint Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice
    M P Schön
    Division of Rheumatology, Immunology, and Allergy, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Immunol 162:6641-9. 1999
  5. ncbi request reprint Retinoic acid receptor signaling levels and antigen dose regulate gut homing receptor expression on CD8+ T cells
    M Svensson
    Section for Immunology, Lund University, Lund, Sweden
    Mucosal Immunol 1:38-48. 2008
  6. pmc Bile retinoids imprint intestinal CD103+ dendritic cells with the ability to generate gut-tropic T cells
    E Jaensson-Gyllenbäck
    Department of Experimental Medical Sciences, Immunology Section, Lund University, Lund, Sweden
    Mucosal Immunol 4:438-47. 2011
  7. pmc Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses
    M Semmrich
    Immunology Section, Lund University, Lund, Sweden
    Mucosal Immunol 5:150-60. 2012
  8. ncbi request reprint T-lymphocyte-epithelial-cell interactions: integrin alpha(E)(CD103)beta(7), LEEP-CAM and chemokines
    W W Agace
    Immunology Section, Department of Cell and Molecular Biology, Lund University, Sweden
    Curr Opin Cell Biol 12:563-8. 2000
  9. doi request reprint A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa
    K Kotarsky
    Immunology Section, Department of Experimental Medical Sciences, Lund University, Lund, Sweden
    Mucosal Immunol 3:40-8. 2010
  10. pmc Role of epithelial interleukin-8 (IL-8) and neutrophil IL-8 receptor A in Escherichia coli-induced transuroepithelial neutrophil migration
    G Godaly
    Department of Medical Microbiology, Lund University, Sweden
    Infect Immun 65:3451-6. 1997

Collaborators

Detail Information

Publications13

  1. pmc Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing
    Bengt Johansson-Lindbom
    Immunology Section, Lund University, BMC I 13, 221 84 Lund, Sweden
    J Exp Med 202:1063-73. 2005
    ..Collectively, these results demonstrate a unique function for LP-derived CD103+ MLN DCs in the generation of gut-tropic effector T cells...
  2. ncbi request reprint Human intestinal lamina propria and intraepithelial lymphocytes express receptors specific for chemokines induced by inflammation
    W W Agace
    Division of Rheumatology, Immunology, and Allergy, Brigham and Women s Hospital and Harvard Medical School, Boston, USA
    Eur J Immunol 30:819-26. 2000
    ..These results support the view that CXCR3, CCR5 and CCR2 may play an important role in lymphocyte localization within the intestinal mucosa...
  3. ncbi request reprint Constitutive expression of stromal derived factor-1 by mucosal epithelia and its role in HIV transmission and propagation
    W W Agace
    Division of Rheumatology, Immunology and Allergy, Brigham and Womens Hospital, Harvard Medical School, Boston 02115, USA
    Curr Biol 10:325-8. 2000
    ..Moreover, such a mechanism could contribute to the delayed emergence of X4 isolates, which predominantly occurs during the later stages of the HIV infection...
  4. ncbi request reprint Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice
    M P Schön
    Division of Rheumatology, Immunology, and Allergy, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Immunol 162:6641-9. 1999
    ..Integrin alpha E-deficient mice will provide an important tool for studying the role of alpha E beta 7 and of alpha E beta 7-expressing mucosal T lymphocytes in vivo...
  5. ncbi request reprint Retinoic acid receptor signaling levels and antigen dose regulate gut homing receptor expression on CD8+ T cells
    M Svensson
    Section for Immunology, Lund University, Lund, Sweden
    Mucosal Immunol 1:38-48. 2008
    ..These results highlight a complex interplay between antigen dose and DC subset-induced RAR signaling events in the generation of tissue tropic effector T-cell subsets...
  6. pmc Bile retinoids imprint intestinal CD103+ dendritic cells with the ability to generate gut-tropic T cells
    E Jaensson-Gyllenbäck
    Department of Experimental Medical Sciences, Immunology Section, Lund University, Lund, Sweden
    Mucosal Immunol 4:438-47. 2011
    ..Taken together, these results suggest a novel and unexpected role for bile in SI-LP CD103(+) DC imprinting...
  7. pmc Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses
    M Semmrich
    Immunology Section, Lund University, Lund, Sweden
    Mucosal Immunol 5:150-60. 2012
    ..These findings identify antigen targeting to CD103(+) DCs as a potential strategy to regulate immune responses in nonlymphoid mucosal tissues...
  8. ncbi request reprint T-lymphocyte-epithelial-cell interactions: integrin alpha(E)(CD103)beta(7), LEEP-CAM and chemokines
    W W Agace
    Immunology Section, Department of Cell and Molecular Biology, Lund University, Sweden
    Curr Opin Cell Biol 12:563-8. 2000
    ..Finally, there have been advances in our understanding of the role of skin- or gut-epithelia-derived chemokines in regulating activated T cell homing to these sites...
  9. doi request reprint A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa
    K Kotarsky
    Immunology Section, Department of Experimental Medical Sciences, Lund University, Lund, Sweden
    Mucosal Immunol 3:40-8. 2010
    ..These findings identify a novel role for constitutively expressed, epithelial-derived chemokines as antimicrobial peptides in the intestinal mucosa...
  10. pmc Role of epithelial interleukin-8 (IL-8) and neutrophil IL-8 receptor A in Escherichia coli-induced transuroepithelial neutrophil migration
    G Godaly
    Department of Medical Microbiology, Lund University, Sweden
    Infect Immun 65:3451-6. 1997
    ..These results demonstrate that IL-8 plays a key role in E. coli- or IL-1alpha-induced transuroepithelial migration and suggest that epithelial cell-produced IL-8 interacts with IL-8RA on the neutrophil surface...
  11. pmc Differential expression of chemokine receptors on human IgA+ and IgG+ B cells
    C Johansson
    Department of Medical Microbiology and Immunology and GUVAX, Göteborg University Vaccine Research Centre, SE 405 30 Goteborg, Sweden
    Clin Exp Immunol 141:279-87. 2005
    ..In contrast, none of the studied chemokine receptors was preferentially expressed by IgA+ cells...
  12. pmc Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity
    E J Kunkel
    Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
    J Exp Med 192:761-8. 2000
    ..Selective expression of chemokines by differentiated epithelium may represent an important mechanism for targeting and specialization of immune responses...
  13. pmc Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis
    B A Zabel
    LeukoSite, Inc, Cambridge, Massachusetts 02142, USA
    J Exp Med 190:1241-56. 1999
    ..The selective expression of TECK and GPR-9-6 in thymus and small intestine implies a dual role for GPR-9-6/CCR-9, both in T cell development and the mucosal immune response...