Research Topics
Genomes and Genes
| J ZilliacusSummaryAffiliation: Karolinska Institutet Country: Sweden Publications
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Detail Information
Publications
Regulation of glucocorticoid receptor activity by 14--3-3-dependent intracellular relocalization of the corepressor RIP140J Zilliacus
Department of Medical Nutrition, Karolinska Institutet NOVUM, S 141 86 Huddinge, Sweden
Mol Endocrinol 15:501-11. 2001..They furthermore indicate a more general role for 14--3-3 protein by influencing the nuclear availability of nuclear receptor-associated cofactors...
Functional interaction of the immunosuppressant mizoribine with the 14-3-3 proteinS Takahashi
Department of Medical Nutrition, Karolinska Institutet, Novum, Huddinge, S 141 86, Sweden
Biochem Biophys Res Commun 274:87-92. 2000..MIZ also has a stimulatory effect on transcriptional activation by the GR. Our results point to the possibility that one mechanism for the therapeutic effect of MIZ could be to regulate the GR function via 14-3-3 proteins...
Glucocorticoid receptor interaction with 14-3-3 and Raf-1, a proposed mechanism for cross-talk of two signal transduction pathwaysC Widén
Department of Medical Nutrition, Karolinska Institutet, Novum, S 141 86 Huddinge, Sweden
J Biol Chem 275:39296-301. 2000....
The pro-apoptotic protein death-associated protein 3 (DAP3) interacts with the glucocorticoid receptor and affects the receptor functionS M Hulkko
Department of Medical Nutrition, Karolinska Institutet, Novum, S 141 86 Huddinge, Sweden
Biochem J 349:885-93. 2000..Since glucocorticoids can induce apoptosis, the pro-apoptotic DAP3 protein may be involved in this function of GR...
Interaction of the ligand-activated glucocorticoid receptor with the 14-3-3 eta proteinH Wakui
Department of Biosciences, Karolinska Institute, Novum, S 141 57 Huddinge, Sweden
J Biol Chem 272:8153-6. 1997..Our findings suggest a novel regulatory role of 14-3-3eta protein in GR-mediated signaling pathways and also point to a mechanism whereby GR may cross-talk with other signal transduction systems...
