Stephanie M Wood

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. doi request reprint Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity
    Stephanie M Wood
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, S 14186 Stockholm, Sweden
    Blood 114:4117-27. 2009
  2. doi request reprint Insights into NK cell biology from human genetics and disease associations
    Stephanie M Wood
    Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186 Stockholm, Sweden
    Cell Mol Life Sci 68:3479-93. 2011
  3. doi request reprint Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations
    Marie Meeths
    Childhood Cancer Research Unit, Department of Woman and Child Health, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
    Pediatr Blood Cancer 54:563-72. 2010
  4. doi request reprint Molecular mechanisms of natural killer cell activation
    Yenan T Bryceson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    J Innate Immun 3:216-26. 2011
  5. doi request reprint Familial hemophagocytic lymphohistiocytosis type 3 (FHL3) caused by deep intronic mutation and inversion in UNC13D
    Marie Meeths
    Childhood Cancer Research Unit, Department of Women s and Children s Health, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
    Blood 118:5783-93. 2011
  6. doi request reprint Functional analysis of human NK cells by flow cytometry
    Yenan T Bryceson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Methods Mol Biol 612:335-52. 2010
  7. doi request reprint Sensitive and viable quantification of inside-out signals for LFA-1 activation in human cytotoxic lymphocytes by flow cytometry
    Jakob Theorell
    Center for Infectious Medicine, Department of Medicine, Karolinska Institute, Karolinska University Hospital Huddinge, Stockholm, Sweden
    J Immunol Methods 366:106-18. 2011
  8. pmc Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients
    Yenan T Bryceson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Blood 110:1906-15. 2007
  9. doi request reprint Spectrum of clinical presentations in familial hemophagocytic lymphohistiocytosis type 5 patients with mutations in STXBP2
    Marie Meeths
    Childhood Cancer Research Unit, Department of Women s and Children s Health, Stockholm, Sweden
    Blood 116:2635-43. 2010

Collaborators

Detail Information

Publications9

  1. doi request reprint Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity
    Stephanie M Wood
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, S 14186 Stockholm, Sweden
    Blood 114:4117-27. 2009
    ..The data suggest Rab27a facilitates degranulation at an early step yet highlight a reciprocal relationship between Munc13-4 and Rab27a for degranulation...
  2. doi request reprint Insights into NK cell biology from human genetics and disease associations
    Stephanie M Wood
    Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186 Stockholm, Sweden
    Cell Mol Life Sci 68:3479-93. 2011
    ..Still, data suggest an important role for NK cells in diseases ranging from classical immunodeficiency syndromes with susceptibility to viruses and other intracellular pathogens to cancer, autoimmunity, and hypersensitivity reactions...
  3. doi request reprint Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations
    Marie Meeths
    Childhood Cancer Research Unit, Department of Woman and Child Health, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
    Pediatr Blood Cancer 54:563-72. 2010
    ..In addition, we report three patients with known GS2. Moreover, neurological involvement and RAB27A mutations in previously published patients with genetically verified GS2 are reviewed...
  4. doi request reprint Molecular mechanisms of natural killer cell activation
    Yenan T Bryceson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    J Innate Immun 3:216-26. 2011
    ..Responses display cellular heterogeneity and are influenced by environmental cues. This review highlights recent knowledge gained on the molecular pathways for and regulation of NK cell activation...
  5. doi request reprint Familial hemophagocytic lymphohistiocytosis type 3 (FHL3) caused by deep intronic mutation and inversion in UNC13D
    Marie Meeths
    Childhood Cancer Research Unit, Department of Women s and Children s Health, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
    Blood 118:5783-93. 2011
    ..Based on these data, we propose a strategy for targeted sequencing of evolutionary conserved noncoding regions for the diagnosis of primary immunodeficiencies...
  6. doi request reprint Functional analysis of human NK cells by flow cytometry
    Yenan T Bryceson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Methods Mol Biol 612:335-52. 2010
    ..In addition to offering insight into the regulation of human NK cell responses, these techniques are applicable to the assessment of various clinical conditions, including the diagnosis of immunodeficiency syndromes...
  7. doi request reprint Sensitive and viable quantification of inside-out signals for LFA-1 activation in human cytotoxic lymphocytes by flow cytometry
    Jakob Theorell
    Center for Infectious Medicine, Department of Medicine, Karolinska Institute, Karolinska University Hospital Huddinge, Stockholm, Sweden
    J Immunol Methods 366:106-18. 2011
    ....
  8. pmc Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients
    Yenan T Bryceson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Blood 110:1906-15. 2007
    ....
  9. doi request reprint Spectrum of clinical presentations in familial hemophagocytic lymphohistiocytosis type 5 patients with mutations in STXBP2
    Marie Meeths
    Childhood Cancer Research Unit, Department of Women s and Children s Health, Stockholm, Sweden
    Blood 116:2635-43. 2010
    ..Mutations in STXBP2 should thus also be considered in patients with clinical manifestations other than those typically associated with HLH...