J Widenfalk

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint NOGO mRNA expression in adult and fetal human and rat nervous tissue and in weight drop injury
    A Josephson
    Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Exp Neurol 169:319-28. 2001
  2. ncbi request reprint Deprived of habitual running, rats downregulate BDNF and TrkB messages in the brain
    J Widenfalk
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Neurosci Res 34:125-32. 1999
  3. ncbi request reprint Vascular endothelial growth factor improves functional outcome and decreases secondary degeneration in experimental spinal cord contusion injury
    J Widenfalk
    Department of Neuroscience, Karolinska Institutet, Retzius vag 8, B2, IV, S 171 77, Stockholm, Sweden
    Neuroscience 120:951-60. 2003
  4. ncbi request reprint Neurotrophic factors and receptors in the immature and adult spinal cord after mechanical injury or kainic acid
    J Widenfalk
    Department of Neuroscience, Karolinska Institute, S 171 77 Stockholm, Sweden
    J Neurosci 21:3457-75. 2001
  5. ncbi request reprint Neurturin, RET, GFRalpha-1 and GFRalpha-2, but not GFRalpha-3, mRNA are expressed in mice gonads
    J Widenfalk
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Cell Tissue Res 299:409-15. 2000
  6. ncbi request reprint GFRalpha-3, a protein related to GFRalpha-1, is expressed in developing peripheral neurons and ensheathing cells
    J Widenfalk
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Eur J Neurosci 10:1508-17. 1998
  7. ncbi request reprint GDNF and NGF family members and receptors in human fetal and adult spinal cord and dorsal root ganglia
    A Josephson
    Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
    J Comp Neurol 440:204-17. 2001
  8. ncbi request reprint Neurturin and glial cell line-derived neurotrophic factor receptor-beta (GDNFR-beta), novel proteins related to GDNF and GDNFR-alpha with specific cellular patterns of expression suggesting roles in the developing and adult nervous system and in periphera
    J Widenfalk
    Department of Neuroscience, Karolinska Institute, S 171 77 Stockholm, Sweden
    J Neurosci 17:8506-19. 1997
  9. ncbi request reprint GDNF, RET and GFRalpha-1-3 mRNA expression in the developing human spinal cord and ganglia
    J Widenfalk
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Neuroreport 10:1433-9. 1999
  10. pmc Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery
    C P Hofstetter
    Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Proc Natl Acad Sci U S A 99:2199-204. 2002

Collaborators

Detail Information

Publications11

  1. ncbi request reprint NOGO mRNA expression in adult and fetal human and rat nervous tissue and in weight drop injury
    A Josephson
    Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Exp Neurol 169:319-28. 2001
    ..In addition to oligodendroglial cells, high levels of nogo-A mRNA expression were found in neurons, raising important questions about the function of neuronal nogo mRNA. No obvious regulation of nogo was detected following injury...
  2. ncbi request reprint Deprived of habitual running, rats downregulate BDNF and TrkB messages in the brain
    J Widenfalk
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Neurosci Res 34:125-32. 1999
    ..We conclude that spontaneous running as well as its abrupt termination, leads to area-specific and trophic factor-specific changes in hippocampus...
  3. ncbi request reprint Vascular endothelial growth factor improves functional outcome and decreases secondary degeneration in experimental spinal cord contusion injury
    J Widenfalk
    Department of Neuroscience, Karolinska Institutet, Retzius vag 8, B2, IV, S 171 77, Stockholm, Sweden
    Neuroscience 120:951-60. 2003
    ....
  4. ncbi request reprint Neurotrophic factors and receptors in the immature and adult spinal cord after mechanical injury or kainic acid
    J Widenfalk
    Department of Neuroscience, Karolinska Institute, S 171 77 Stockholm, Sweden
    J Neurosci 21:3457-75. 2001
    ..The relative sparseness of upregulations of endogenous neurotrophic factors after injury strengthens the hypothesis that lack of regeneration in the spinal cord is attributable at least partly to lack of trophic support...
  5. ncbi request reprint Neurturin, RET, GFRalpha-1 and GFRalpha-2, but not GFRalpha-3, mRNA are expressed in mice gonads
    J Widenfalk
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Cell Tissue Res 299:409-15. 2000
    ..GFRalpha-3 could not be detected. Expression of these trophic molecules suggests involvement of GDNF family ligands and related receptor components in reproduction...
  6. ncbi request reprint GFRalpha-3, a protein related to GFRalpha-1, is expressed in developing peripheral neurons and ensheathing cells
    J Widenfalk
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Eur J Neurosci 10:1508-17. 1998
    ....
  7. ncbi request reprint GDNF and NGF family members and receptors in human fetal and adult spinal cord and dorsal root ganglia
    A Josephson
    Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
    J Comp Neurol 440:204-17. 2001
    ..Notably, GFR alpha-2, which is expressed in the adult rat spinal cord, was not found in the adult human spinal cord...
  8. ncbi request reprint Neurturin and glial cell line-derived neurotrophic factor receptor-beta (GDNFR-beta), novel proteins related to GDNF and GDNFR-alpha with specific cellular patterns of expression suggesting roles in the developing and adult nervous system and in periphera
    J Widenfalk
    Department of Neuroscience, Karolinska Institute, S 171 77 Stockholm, Sweden
    J Neurosci 17:8506-19. 1997
    ..Although NTN and GDNFR-beta expression patterns are sometimes complementary, this is not always the case, suggesting multiple modi operandi of GDNF and NTN in relation to RET and the two binding proteins, GDNFR-alpha and GDNFR-beta...
  9. ncbi request reprint GDNF, RET and GFRalpha-1-3 mRNA expression in the developing human spinal cord and ganglia
    J Widenfalk
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Neuroreport 10:1433-9. 1999
    ..We conclude that basic features concerning the role of the GDNF family of ligands and their receptors revealed in rodents applies to humans...
  10. pmc Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery
    C P Hofstetter
    Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Proc Natl Acad Sci U S A 99:2199-204. 2002
    ..MSC constitute an easily accessible, easily expandable source of cells that may prove useful in the establishment of spinal cord repair protocols...
  11. ncbi request reprint TrkB and neurotrophin-4 are important for development and maintenance of sympathetic preganglionic neurons innervating the adrenal medulla
    A Schober
    Department of Anatomy and Cell Biology III, University of Heidelberg, D 69120 Heidelberg, Germany
    J Neurosci 18:7272-84. 1998
    ..These data are consistent with the notion that NT-4 from chromaffin cells operates through TrkB receptors to regulate development and maintenance of the preganglionic innervation of the adrenal medulla...