Andrej Weintraub

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Structural studies of the O-antigenic polysaccharides from the enteroaggregative Escherichia coli strain 522/C1 and the international type strain from Escherichia coli O 178
    Tara Ali
    Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S 106 91 Stockholm, Sweden
    Carbohydr Res 340:2010-4. 2005
  2. ncbi request reprint Etiology and epidemiology of diarrhea in children in Hanoi, Vietnam
    Trung Vu Nguyen
    Department of Medical Microbiology, Hanoi Medical University, Hanoi, Vietnam
    Int J Infect Dis 10:298-308. 2006
  3. ncbi request reprint The structures of Escherichia coli O-polysaccharide antigens
    Roland Stenutz
    Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden
    FEMS Microbiol Rev 30:382-403. 2006
  4. ncbi request reprint Enteroaggregative Escherichia coli: epidemiology, virulence and detection
    Andrej Weintraub
    Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska University Hospital, Huddinge, 14186 Stockholm, Sweden
    J Med Microbiol 56:4-8. 2007
  5. doi request reprint Ecological impact of doxycycline at low dose on normal oropharyngeal and intestinal microflora
    Mamun Ur Rashid
    Department of Laboratory Medicine, Karolinska University Hospital, Karolinska Institutet, SE 141 86 Stockholm, Sweden
    Int J Antimicrob Agents 41:352-7. 2013
  6. ncbi request reprint Vibrio cholerae O1 strains are facultative intracellular bacteria, able to survive and multiply symbiotically inside the aquatic free-living amoeba Acanthamoeba castellanii
    Hadi Abd
    Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska Institute, Karolinska University Hospital Huddinge, SE 141 86 Stockholm, Sweden
    FEMS Microbiol Ecol 60:33-9. 2007
  7. doi request reprint In vitro activity of cadazolid against Clostridium difficile strains isolated from primary and recurrent infections in Stockholm, Sweden
    Mamun Ur Rashid
    Department of Laboratory Medicine, Karolinska University Hospital, Karolinska Institutet, SE 141 86 Stockholm, Sweden
    Anaerobe 20:32-5. 2013
  8. doi request reprint Effect of telavancin on human intestinal microflora
    Mamun Ur Rashid
    Department of Laboratory Medicine, Karolinska University Hospital, Karolinska Institutet, SE 141 86 Stockholm, Sweden
    Int J Antimicrob Agents 38:474-9. 2011
  9. ncbi request reprint Intracellular survival and replication of Vibrio cholerae O139 in aquatic free-living amoebae
    Hadi Abd
    Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
    Environ Microbiol 7:1003-8. 2005
  10. doi request reprint Effect of new antimicrobial agents on the ecological balance of human microflora
    Mamun Ur Rashid
    Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
    Anaerobe 18:249-53. 2012

Collaborators

  • Abu SG Faruque
  • Carl Erik Nord
  • Hadi Abd
  • G Balakrish Nair
  • M John Albert
  • Gunnar Sandström
  • F Scheutz
  • Bin Liu
  • Lu Feng
  • Edward Ryan
  • Claude Parsot
  • David A Sack
  • Ann Mari Svennerholm
  • A V Perepelov
  • F Qadri
  • Mamun Ur Rashid
  • Goran Widmalm
  • Tara Ali
  • Trung Vu Nguyen
  • Ulrika Olsson
  • Felipe Urbina
  • Susanna Falklind-Jerkérus
  • Roland Stenutz
  • Chinh Le Huy
  • Phung Le Van
  • Erick Amaya
  • David Gonzalez
  • Barbro Selander
  • K Hanna M Jonsson
  • Khanh Nguyen Gia
  • Zhennai Yang
  • E Andreas Larsson
  • Shah M Faruque
  • Hélène d'Hauteville
  • Helena Martinez Lozano
  • Tobias Backström
  • Georgios Panagiotidis
  • Samuel Vilchez
  • Margarita Paniagua
  • Daniel Reyes
  • Roland Möllby
  • Michel Zygmunt
  • Pilar Munoz
  • Ignacio Moriyon
  • Jean Jacques Letesson
  • María Jesús de Miguel
  • Raquel Conde-Alvarez
  • Maite Iriarte
  • Jean Pierre Gorvel
  • Rose May Delrue
  • Maria Jesus Grillo
  • Vilma Arce-Gorvel
  • Jose Maria Blasco
  • Ignacio López-Goñi
  • Clara M Marin
  • Ulla Martensson
  • Eva Holmström
  • Lennart Truedsson
  • Anders G Sjöholm
  • Steffen Thiel
  • Misao Matsushita
  • Jens C Jensenius
  • Chinh Huy Le
  • Eva Lisa Nordmark
  • Ida Pernice
  • Kristina Lycknert
  • Carla Lo Passo
  • Muhammad M Islam
  • Gabriella Garufi
  • Phung Van Le
  • Franco Felici
  • Cristina Cavalieri
  • M Abdus Salam
  • Q Shafi Ahmad
  • M Kamruzzaman
  • Nityananda Chowdhury
  • T Ramamurthy
  • Anders Kussak
  • Philippe J Sansonetti
  • Duncan J Maskell
  • Nicole Wuscher
  • John Mathison
  • Richard J Ulevitch
  • Shahid Khan

Detail Information

Publications31

  1. ncbi request reprint Structural studies of the O-antigenic polysaccharides from the enteroaggregative Escherichia coli strain 522/C1 and the international type strain from Escherichia coli O 178
    Tara Ali
    Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S 106 91 Stockholm, Sweden
    Carbohydr Res 340:2010-4. 2005
    ..In addition, this pentasaccharide repeating unit is identical to that of the capsular polysaccharide from E. coli O9:K 38, which also contains O-acetyl groups...
  2. ncbi request reprint Etiology and epidemiology of diarrhea in children in Hanoi, Vietnam
    Trung Vu Nguyen
    Department of Medical Microbiology, Hanoi Medical University, Hanoi, Vietnam
    Int J Infect Dis 10:298-308. 2006
    ..This paper provides a preliminary picture of diarrhea with regards to etiology, clinical symptoms, and some related epidemiologic factors in children less than five years of age living in Hanoi, Vietnam...
  3. ncbi request reprint The structures of Escherichia coli O-polysaccharide antigens
    Roland Stenutz
    Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden
    FEMS Microbiol Rev 30:382-403. 2006
    ..In addition, results pertinent to the biosynthesis of the repeating units of O-antigens are discussed. The ECODAB is accessible to the scientific community at http://www.casper.organ.su.se/ECODAB/...
  4. ncbi request reprint Enteroaggregative Escherichia coli: epidemiology, virulence and detection
    Andrej Weintraub
    Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska University Hospital, Huddinge, 14186 Stockholm, Sweden
    J Med Microbiol 56:4-8. 2007
    ..In addition, the HEp-2 assay is time consuming, demands a tissue culture lab and trained staff. Several molecular biological assays have been described, however, none show 100 % specificity...
  5. doi request reprint Ecological impact of doxycycline at low dose on normal oropharyngeal and intestinal microflora
    Mamun Ur Rashid
    Department of Laboratory Medicine, Karolinska University Hospital, Karolinska Institutet, SE 141 86 Stockholm, Sweden
    Int J Antimicrob Agents 41:352-7. 2013
    ..The anaerobic intestinal microflora in the doxycycline and placebo groups was not changed, and no Clostridium difficile strains were isolated...
  6. ncbi request reprint Vibrio cholerae O1 strains are facultative intracellular bacteria, able to survive and multiply symbiotically inside the aquatic free-living amoeba Acanthamoeba castellanii
    Hadi Abd
    Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska Institute, Karolinska University Hospital Huddinge, SE 141 86 Stockholm, Sweden
    FEMS Microbiol Ecol 60:33-9. 2007
    ..castellanii. The interaction showed a facultative intracellular behaviour of V. cholerae O1 classical and El Tor strains and a possible role of A. castellanii as an environmental host of V. cholerae species...
  7. doi request reprint In vitro activity of cadazolid against Clostridium difficile strains isolated from primary and recurrent infections in Stockholm, Sweden
    Mamun Ur Rashid
    Department of Laboratory Medicine, Karolinska University Hospital, Karolinska Institutet, SE 141 86 Stockholm, Sweden
    Anaerobe 20:32-5. 2013
    ..No association between toxins A, B and binary toxin, ribotypes or the sporulation and the sensitivity to cadazolid could be found. Cadazolid has a potent in vitro activity against C. difficile...
  8. doi request reprint Effect of telavancin on human intestinal microflora
    Mamun Ur Rashid
    Department of Laboratory Medicine, Karolinska University Hospital, Karolinska Institutet, SE 141 86 Stockholm, Sweden
    Int J Antimicrob Agents 38:474-9. 2011
    ..Based on the microbiological data, telavancin has no significant ecological impact on the human intestinal microflora...
  9. ncbi request reprint Intracellular survival and replication of Vibrio cholerae O139 in aquatic free-living amoebae
    Hadi Abd
    Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
    Environ Microbiol 7:1003-8. 2005
    ..cholerae contradicting the generally held view, and a role of free-living amoebae as hosts for V. cholerae O139. Taken together, this opens new doors to study the ecology, immunity, epidemiology, and treatment of cholera...
  10. doi request reprint Effect of new antimicrobial agents on the ecological balance of human microflora
    Mamun Ur Rashid
    Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
    Anaerobe 18:249-53. 2012
    ..In this article, the potential ecological effects of administration of new antimicrobial agents on the intestinal and oropharyngeal microflora are summarized. The review is based on clinical studies published during the past 10 years...
  11. doi request reprint Antibiotic resistance patterns of intestinal Escherichia coli isolates from Nicaraguan children
    Erick Amaya
    Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska Institutet, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
    J Med Microbiol 60:216-22. 2011
    ..coli isolates. The results suggest that E. coli isolates from Nicaraguan children have not reached the high levels of resistance to the most common antibiotics used for diarrhoea treatment as in other countries...
  12. ncbi request reprint Peptides mimicking Vibrio cholerae O139 capsular polysaccharide elicit protective antibody response
    Susanna Falklind-Jerkérus
    Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden
    Microbes Infect 7:1453-60. 2005
    ..The protective efficacy is both specific and dose-dependent. A PCT (PCT/IT2003/000489) with the publication number WO 2004/056851 has been filed for the sequences of the eight peptides...
  13. ncbi request reprint Structural determination of the O-antigenic polysaccharide from Escherichia coli O166
    Tara Ali
    Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, and Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska University Hospital, S 141 86 Stockholm, Sweden
    Carbohydr Res 342:274-8. 2007
    ..Further analysis of these showed that they originate from the terminal part of the polysaccharide, thereby revealing that the repeating unit has a 3-substituted N-acetyl-D-galactosamine residue at its reducing end...
  14. ncbi request reprint Structural elucidation of the O-antigenic polysaccharide from the enteroaggregative Escherichia coli strain 180/C3 and its immunochemical relationship with E. coli O5 and O65
    Felipe Urbina
    Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska Institutet, Karolinska University Hospital, Huddinge, S 141 86 Stockholm, Sweden
    Carbohydr Res 340:645-50. 2005
    ..The anti-O65 serum did react with both the 180/C3 and O5 LPS showing a partial cross-reactivity...
  15. ncbi request reprint Immunology of bacterial polysaccharide antigens
    Andrej Weintraub
    Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Bacteriology, Huddinge University Hospital, S 141 86 Stockholm, Sweden
    Carbohydr Res 338:2539-47. 2003
    ..Another approach to circumvent the T-lymphocyte independent property of polysaccharides is to select peptides mimicking the immunodominant structures. Several examples of such peptides have been described...
  16. ncbi request reprint Lack of polymorphism in a Vibrio cholerae O139-specific DNA region encoding the somatic antigen in strains isolated during 1993-1998
    Susanna Falklind-Jerkérus
    Karolinska Institute, Department of Microbiology, Pathology and Immunology, Division of Clinical Bacteriology, Huddinge University Hospital, Stockholm, Sweden
    Int J Med Microbiol 292:505-11. 2003
    ..The isolates of later years diverged exhibiting different patterns by pulsed-field gel electrophoresis (PFGE), and becoming susceptible to TMP-SMX and O/129, and CAMP-haemolysin negative...
  17. doi request reprint Structural studies of the O-antigenic polysaccharides from the enteroaggregative Escherichia coli strain 87/D2 and international type strains from E. coli O128
    Tara Ali
    Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, and Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska University Hospital, S 141 86 Stockholm, Sweden
    Carbohydr Res 343:695-702. 2008
    ..coli strain 87/D2, whereas the O-acetyl substitution pattern in the E. coli O128ac O-antigen differed slightly. Enzyme immunoassay using specific anti-E. coli O128ab and anti-E. coli O128ac rabbit sera confirmed the results...
  18. pmc Antibiotic resistance in diarrheagenic Escherichia coli and Shigella strains isolated from children in Hanoi, Vietnam
    Trung Vu Nguyen
    Department of Medical Microbiology, Hanoi Medical University, Vietnam
    Antimicrob Agents Chemother 49:816-9. 2005
    ..More than 75% of the strains were resistant to ampicillin, chloramphenicol (53.6% of Shigella strains), and trimethoprim-sulfamethoxazole. Multiresistance was detected in 89.5% of E. coli strains and 78.6% of Shigella strains...
  19. pmc Detection and characterization of diarrheagenic Escherichia coli from young children in Hanoi, Vietnam
    Trung Vu Nguyen
    Department of Medical Microbiology, Hanoi Medical University, Hanoi, Vietnam
    J Clin Microbiol 43:755-60. 2005
    ..2%) with ETEC. Among the 249 age-matched controls, 30 samples were positive for diarrheagenic E. coli. The distribution was 18 samples (7.2%) with EAEC, 11 samples (4.4%) with EPEC, and 1 sample (0.4%) with ETEC...
  20. doi request reprint Structural determination of the O-antigenic polysaccharide from the verocytotoxin-producing Escherichia coli O176
    Ulrika Olsson
    Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S 106 91 Stockholm, Sweden
    Carbohydr Res 343:805-9. 2008
    ..The repeating unit of the E. coli O176 O-antigen is similar to those from E. coli O17 and O77, thereby explaining the reported cross-reactivities between the strains, and identical to that of Salmonella cerro (O:6, 14, 18)...
  21. pmc Brucellosis vaccines: assessment of Brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export
    David Gonzalez
    Department of Microbiology and Parasitology, University of Navarra, Pamplona, Spain
    PLoS ONE 3:e2760. 2008
    ..Because of this, rough Brucella mutants lacking the O-polysaccharide have been proposed as vaccines...
  22. doi request reprint The O-polysaccharide of Escherichia coli O112ac has the same structure as that of Shigella dysenteriae type 2 but is devoid of O-acetylation: a revision of the S. dysenteriae type 2 O-polysaccharide structure
    Andrei V Perepelov
    N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation
    Carbohydr Res 343:977-81. 2008
    ..The O-antigen of Escherichia coli O112ac was found to have the same carbohydrate structure but to lack O-acetylation...
  23. ncbi request reprint Structural studies of the O-antigenic polysaccharides from Shigella dysenteriae type 3 and Escherichia coli O124, a reinvestigation
    K Hanna M Jonsson
    Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S 106 91 Stockholm, Sweden
    Carbohydr Res 341:2986-9. 2006
    ..The structures of the repeating units also explain the previously observed cross-reactivity between the strains and to E. coli O164, which only differs in the terminal sugar residue that is lacking the (R)-1-carboxyethyl group...
  24. pmc Reemergence of epidemic Vibrio cholerae O139, Bangladesh
    Shah M Faruque
    International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Emerg Infect Dis 9:1116-22. 2003
    ..These findings emphasize the need for continuous monitoring of the new epidemic strains...
  25. ncbi request reprint Structural and immunochemical relationship between the O-antigenic polysaccharides from the enteroaggregative Escherichia coli strain 396/C-1 and Escherichia coli O126
    E Andreas Larsson
    Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S 106 91 Stockholm, Sweden
    Carbohydr Res 339:1491-6. 2004
    ..coli strain 396/C-1 and the E. coli O126 reference strain, neither in slide agglutination nor in an indirect enzyme immunoassay. Subsequent successful serotyping of the E. coli strain 396/C-1 showed it to be E. coli O126:K+:H27...
  26. pmc Diarrhea caused by rotavirus in children less than 5 years of age in Hanoi, Vietnam
    Trung Vu Nguyen
    Department of Medical Microbiology, Hanoi Medical University, Vietnam
    J Clin Microbiol 42:5745-50. 2004
    ..Continuous surveillance of diarrhea caused by rotavirus in young children would play an important role in diagnosis, treatment, and prophylaxis in order to improve the health of children in Vietnam...
  27. ncbi request reprint Structural analysis of the O-antigen polysaccharide from Escherichia coli O152
    Ulrika Olsson
    Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S 106 91 Stockholm, Sweden
    Carbohydr Res 340:167-71. 2005
    ..coli O173. The cross-reactivity between E. coli O152 and E. coli O3 may be explained by structural similarities in the branching region of their O-antigen polysaccharides...
  28. pmc Reduction in capsular content and enhanced bacterial susceptibility to serum killing of Vibrio cholerae O139 associated with the 2002 cholera epidemic in Bangladesh
    Firdausi Qadri
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka
    Infect Immun 73:6577-83. 2005
    ..cholerae O139. Consequently, this assay may be useful in studies of both O139-infected patients and recipients of O139 vaccines...
  29. pmc Mannan-binding lectin activates C3 and the alternative complement pathway without involvement of C2
    Barbro Selander
    Institute of Laboratory Medicine, Section of Microbiology, Immunology, and Glycobiology, Lund University, Lund, Sweden
    J Clin Invest 116:1425-34. 2006
    ..MBL-dependent C2 bypass activation could be particularly important in various inherited and acquired complement deficiency states...
  30. ncbi request reprint Structural determination of the O-antigenic polysaccharide from the Shiga toxin-producing Escherichia coli O171
    Tara Ali
    Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Sweden
    Carbohydr Res 341:1878-83. 2006
    ....
  31. ncbi request reprint Two msbB genes encoding maximal acylation of lipid A are required for invasive Shigella flexneri to mediate inflammatory rupture and destruction of the intestinal epithelium
    Hélène d'Hauteville
    Unité de Pathogénie Microbienne Moléculaire and Institut National de la Santé et de la Recherche Médicale, Unité 389, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
    J Immunol 168:5240-51. 2002
    ....