Research Topics
| Andrej WeintraubSummaryAffiliation: Karolinska Institutet Country: Sweden Publications
| Collaborators
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Detail Information
Publications
Structural studies of the O-antigenic polysaccharides from the enteroaggregative Escherichia coli strain 522/C1 and the international type strain from Escherichia coli O 178Tara Ali
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S-106 91 Stockholm, Sweden
Carbohydr Res 340:2010-4. 2005..In addition, this pentasaccharide repeating unit is identical to that of the capsular polysaccharide from E. coli O9:K 38, which also contains O-acetyl groups...- Etiology and epidemiology of diarrhea in children in Hanoi, VietnamTrung Vu Nguyen
Department of Medical Microbiology, Hanoi Medical University, Hanoi, Vietnam
Int J Infect Dis 10:298-308. 2006..Epidemiological factors such as lack of fresh water supply, unhygienic septic tank, low family income, lack of health information, and low educational level of parents could contribute to the morbidity of diarrhea in children... - The structures of Escherichia coli O-polysaccharide antigensRoland Stenutz
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden
FEMS Microbiol Rev 30:382-403. 2006..In addition, results pertinent to the biosynthesis of the repeating units of O-antigens are discussed. The ECODAB is accessible to the scientific community at http://www.casper.organ.su.se/ECODAB/... - Enteroaggregative Escherichia coli: epidemiology, virulence and detectionAndrej Weintraub
Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska University Hospital, Huddinge, 14186 Stockholm, Sweden
J Med Microbiol 56:4-8. 2007..In addition, the HEp-2 assay is time consuming, demands a tissue culture lab and trained staff. Several molecular biological assays have been described, however, none show 100 % specificity... - Vibrio cholerae O1 strains are facultative intracellular bacteria, able to survive and multiply symbiotically inside the aquatic free-living amoeba Acanthamoeba castellaniiHadi Abd
Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska Institute, Karolinska University Hospital Huddinge, SE 141 86 Stockholm, Sweden
FEMS Microbiol Ecol 60:33-9. 2007..castellanii. The interaction showed a facultative intracellular behaviour of V. cholerae O1 classical and El Tor strains and a possible role of A. castellanii as an environmental host of V. cholerae species... 
Effect of telavancin on human intestinal microfloraMamun Ur Rashid
Department of Laboratory Medicine, Karolinska University Hospital, Karolinska Institutet, SE 141 86 Stockholm, Sweden
Int J Antimicrob Agents 38:474-9. 2011..Based on the microbiological data, telavancin has no significant ecological impact on the human intestinal microflora...- Intracellular survival and replication of Vibrio cholerae O139 in aquatic free-living amoebaeHadi Abd
Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska University Hospital, Huddinge, SE-141 86 Stockholm, Sweden
Environ Microbiol 7:1003-8. 2005..cholerae contradicting the generally held view, and a role of free-living amoebae as hosts for V. cholerae O139. Taken together, this opens new doors to study the ecology, immunity, epidemiology, and treatment of cholera... - In vitro activity of cadazolid against Clostridium difficile strains isolated from primary and recurrent infections in Stockholm, SwedenMamun Ur Rashid
Department of Laboratory Medicine, Karolinska University Hospital, Karolinska Institutet, SE 141 86 Stockholm, Sweden
Anaerobe 20:32-5. 2013..No association between toxins A, B and binary toxin, ribotypes or the sporulation and the sensitivity to cadazolid could be found. Cadazolid has a potent in vitro activity against C. difficile... - Ecological impact of doxycycline at low dose on normal oropharyngeal and intestinal microfloraMamun Ur Rashid
Department of Laboratory Medicine, Karolinska University Hospital, Karolinska Institutet, SE 141 86 Stockholm, Sweden
Int J Antimicrob Agents 41:352-7. 2013..The anaerobic intestinal microflora in the doxycycline and placebo groups was not changed, and no Clostridium difficile strains were isolated... - Effect of new antimicrobial agents on the ecological balance of human microfloraMamun Ur Rashid
Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
Anaerobe 18:249-53. 2012..In this article, the potential ecological effects of administration of new antimicrobial agents on the intestinal and oropharyngeal microflora are summarized. The review is based on clinical studies published during the past 10 years... - Antibiotic resistance patterns of intestinal Escherichia coli isolates from Nicaraguan childrenErick Amaya
Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska Institutet, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
J Med Microbiol 60:216-22. 2011..coli isolates. The results suggest that E. coli isolates from Nicaraguan children have not reached the high levels of resistance to the most common antibiotics used for diarrhoea treatment as in other countries... - Peptides mimicking Vibrio cholerae O139 capsular polysaccharide elicit protective antibody responseSusanna Falklind-Jerkérus
Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden
Microbes Infect 7:1453-60. 2005..The protective efficacy is both specific and dose-dependent. A PCT (PCT/IT2003/000489) with the publication number WO 2004/056851 has been filed for the sequences of the eight peptides... - Structural determination of the O-antigenic polysaccharide from Escherichia coli O166Tara Ali
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, and Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska University Hospital, S 141 86 Stockholm, Sweden
Carbohydr Res 342:274-8. 2007..Further analysis of these showed that they originate from the terminal part of the polysaccharide, thereby revealing that the repeating unit has a 3-substituted N-acetyl-D-galactosamine residue at its reducing end... - Structural elucidation of the O-antigenic polysaccharide from the enteroaggregative Escherichia coli strain 180/C3 and its immunochemical relationship with E. coli O5 and O65Felipe Urbina
Department of Laboratory Medicine, Division of Clinical Bacteriology, Karolinska Institutet, Karolinska University Hospital, Huddinge, S-141 86 Stockholm, Sweden
Carbohydr Res 340:645-50. 2005..The anti-O65 serum did react with both the 180/C3 and O5 LPS showing a partial cross-reactivity... - Lack of polymorphism in a Vibrio cholerae O139-specific DNA region encoding the somatic antigen in strains isolated during 1993-1998Susanna Falklind-Jerkérus
Karolinska Institute, Department of Microbiology, Pathology and Immunology, Division of Clinical Bacteriology, Huddinge University Hospital, Stockholm, Sweden
Int J Med Microbiol 292:505-11. 2003..The isolates of later years diverged exhibiting different patterns by pulsed-field gel electrophoresis (PFGE), and becoming susceptible to TMP-SMX and O/129, and CAMP-haemolysin negative... - Immunology of bacterial polysaccharide antigensAndrej Weintraub
Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Bacteriology, Huddinge University Hospital, S 141 86 Stockholm, Sweden
Carbohydr Res 338:2539-47. 2003..Another approach to circumvent the T-lymphocyte independent property of polysaccharides is to select peptides mimicking the immunodominant structures. Several examples of such peptides have been described... - Structural studies of the O-antigenic polysaccharides from the enteroaggregative Escherichia coli strain 87/D2 and international type strains from E. coli O128Tara Ali
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, and Karolinska Institute, Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska University Hospital, S 141 86 Stockholm, Sweden
Carbohydr Res 343:695-702. 2008..coli strain 87/D2, whereas the O-acetyl substitution pattern in the E. coli O128ac O-antigen differed slightly. Enzyme immunoassay using specific anti-E. coli O128ab and anti-E. coli O128ac rabbit sera confirmed the results... 
Antibiotic resistance in diarrheagenic Escherichia coli and Shigella strains isolated from children in Hanoi, VietnamTrung Vu Nguyen
Department of Medical Microbiology, Hanoi Medical University, Vietnam
Antimicrob Agents Chemother 49:816-9. 2005..More than 75% of the strains were resistant to ampicillin, chloramphenicol (53.6% of Shigella strains), and trimethoprim-sulfamethoxazole. Multiresistance was detected in 89.5% of E. coli strains and 78.6% of Shigella strains...- Detection and characterization of diarrheagenic Escherichia coli from young children in Hanoi, VietnamTrung Vu Nguyen
Department of Medical Microbiology, Hanoi Medical University, Hanoi, Vietnam
J Clin Microbiol 43:755-60. 2005..2%) with ETEC. Among the 249 age-matched controls, 30 samples were positive for diarrheagenic E. coli. The distribution was 18 samples (7.2%) with EAEC, 11 samples (4.4%) with EPEC, and 1 sample (0.4%) with ETEC... - Structural determination of the O-antigenic polysaccharide from the verocytotoxin-producing Escherichia coli O176Ulrika Olsson
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S 106 91 Stockholm, Sweden
Carbohydr Res 343:805-9. 2008..The repeating unit of the E. coli O176 O-antigen is similar to those from E. coli O17 and O77, thereby explaining the reported cross-reactivities between the strains, and identical to that of Salmonella cerro (O:6, 14, 18)... - Brucellosis vaccines: assessment of Brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and exportDavid Gonzalez
Department of Microbiology and Parasitology, University of Navarra, Pamplona, Spain
PLoS ONE 3:e2760. 2008..Because of this, rough Brucella mutants lacking the O-polysaccharide have been proposed as vaccines... - The O-polysaccharide of Escherichia coli O112ac has the same structure as that of Shigella dysenteriae type 2 but is devoid of O-acetylation: a revision of the S. dysenteriae type 2 O-polysaccharide structureAndrei V Perepelov
N D Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation
Carbohydr Res 343:977-81. 2008..The O-antigen of Escherichia coli O112ac was found to have the same carbohydrate structure but to lack O-acetylation... - Structural studies of the O-antigenic polysaccharides from Shigella dysenteriae type 3 and Escherichia coli O124, a reinvestigationK Hanna M Jonsson
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S-106 91 Stockholm, Sweden
Carbohydr Res 341:2986-9. 2006..The structures of the repeating units also explain the previously observed cross-reactivity between the strains and to E. coli O164, which only differs in the terminal sugar residue that is lacking the (R)-1-carboxyethyl group... - Reemergence of epidemic Vibrio cholerae O139, BangladeshShah M Faruque
International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
Emerg Infect Dis 9:1116-22. 2003..These findings emphasize the need for continuous monitoring of the new epidemic strains... - Structural and immunochemical relationship between the O-antigenic polysaccharides from the enteroaggregative Escherichia coli strain 396/C-1 and Escherichia coli O126E Andreas Larsson
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S-106 91 Stockholm, Sweden
Carbohydr Res 339:1491-6. 2004..coli strain 396/C-1 and the E. coli O126 reference strain, neither in slide agglutination nor in an indirect enzyme immunoassay. Subsequent successful serotyping of the E. coli strain 396/C-1 showed it to be E. coli O126:K+:H27... - Diarrhea caused by rotavirus in children less than 5 years of age in Hanoi, VietnamTrung Vu Nguyen
Department of Medical Microbiology, Hanoi Medical University, Vietnam
J Clin Microbiol 42:5745-50. 2004..Continuous surveillance of diarrhea caused by rotavirus in young children would play an important role in diagnosis, treatment, and prophylaxis in order to improve the health of children in Vietnam... - Structural analysis of the O-antigen polysaccharide from Escherichia coli O152Ulrika Olsson
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S-106 91 Stockholm, Sweden
Carbohydr Res 340:167-71. 2005..coli O173. The cross-reactivity between E. coli O152 and E. coli O3 may be explained by structural similarities in the branching region of their O-antigen polysaccharides... - Reduction in capsular content and enhanced bacterial susceptibility to serum killing of Vibrio cholerae O139 associated with the 2002 cholera epidemic in BangladeshFirdausi Qadri
International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka
Infect Immun 73:6577-83. 2005..cholerae O139. Consequently, this assay may be useful in studies of both O139-infected patients and recipients of O139 vaccines... - Mannan-binding lectin activates C3 and the alternative complement pathway without involvement of C2Barbro Selander
Institute of Laboratory Medicine, Section of Microbiology, Immunology, and Glycobiology, Lund University, Lund, Sweden
J Clin Invest 116:1425-34. 2006..MBL-dependent C2 bypass activation could be particularly important in various inherited and acquired complement deficiency states... - Structural determination of the O-antigenic polysaccharide from the Shiga toxin-producing Escherichia coli O171Tara Ali
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Sweden
Carbohydr Res 341:1878-83. 2006.... - Two msbB genes encoding maximal acylation of lipid A are required for invasive Shigella flexneri to mediate inflammatory rupture and destruction of the intestinal epitheliumShahid Khan
, , Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
J Immunol 168:5240-51. 2002....