M Warner

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi Cytochrome P450 in the breast and brain: role in tissue-specific activation of xenobiotics
    M Warner
    Center for Nutrition and Toxicology, Karolinska Institute, Huddinge, Sweden
    Mutat Res 376:79-85. 1997
  2. ncbi Estrogen receptor beta in the breast: role in estrogen responsiveness and development of breast cancer
    J A Gustafsson
    Department of Medical Nutrition, Novum, Karolinska Institute, Huddinge University Hospital, S 141 86, Huddinge, Sweden
    J Steroid Biochem Mol Biol 74:245-8. 2000
  3. ncbi Mechanisms of estrogen action
    S Nilsson
    KaroBio AB and Department of Biosciences, Karolinska Institute, Novum, Huddinge, Sweden
    Physiol Rev 81:1535-65. 2001
  4. pmc Estrogen receptors alpha and beta in the rodent mammary gland
    S Saji
    Department of Medical Nutrition, Karolinska Institute, Novum, S 141 86 Huddinge, Sweden
    Proc Natl Acad Sci U S A 97:337-42. 2000
  5. ncbi Quantitative analysis of estrogen receptor proteins in rat mammary gland
    S Saji
    Department of Medical Nutrition, Karolinska Institute, Novum, S141-86 Huddinge, Sweden
    Endocrinology 142:3177-86. 2001
  6. ncbi Mechanism of oestrogen signalling with particular reference to the role of ER beta in the central nervous system
    E Treuter
    Karolinska Institutet, Department of Biosciences at Novum, Huddinge, Sweden
    Novartis Found Symp 230:7-14; discussion 15-9. 2000
  7. doi Spatiotemporal dynamics of the expression of estrogen receptors in the postnatal mouse brain
    N Sugiyama
    Department of Biosciences and Nutrition, Karolinska Institute, Novum, Huddinge, Sweden
    Mol Psychiatry 14:223-32, 117. 2009
  8. ncbi Identification of CYP2A3 as a major cytochrome P450 enzyme in the female peripubertal rat breast
    H Hellmold
    Department of Medical Nutrition, Karolinska Institute, Novum, S 141 86 Huddinge, Sweden
    Mol Pharmacol 53:475-82. 1998
  9. pmc Estrogen receptors and proliferation markers in primary and recurrent breast cancer
    E V Jensen
    Departments of Medical Nutrition and Biosciences, Karolinska Institute, Novum, S-141 86 Huddinge, Sweden
    Proc Natl Acad Sci U S A 98:15197-202. 2001
  10. doi Biological functions and clinical implications of oestrogen receptors alfa and beta in epithelial tissues
    A Morani
    From the Departments of Biosciences and Nutrition, Karolinska Institutet, Novum, Huddinge, Sweden
    J Intern Med 264:128-42. 2008

Collaborators

Detail Information

Publications12

  1. ncbi Cytochrome P450 in the breast and brain: role in tissue-specific activation of xenobiotics
    M Warner
    Center for Nutrition and Toxicology, Karolinska Institute, Huddinge, Sweden
    Mutat Res 376:79-85. 1997
    ..The cells in which this activation can occur remain to be identified...
  2. ncbi Estrogen receptor beta in the breast: role in estrogen responsiveness and development of breast cancer
    J A Gustafsson
    Department of Medical Nutrition, Novum, Karolinska Institute, Huddinge University Hospital, S 141 86, Huddinge, Sweden
    J Steroid Biochem Mol Biol 74:245-8. 2000
    ..Studies of the breasts of ERbeta knock out mice (BERKO) revealed abnormal epithelial growth, overexpression of Ki67 and severe cystic breast disease as mice age...
  3. ncbi Mechanisms of estrogen action
    S Nilsson
    KaroBio AB and Department of Biosciences, Karolinska Institute, Novum, Huddinge, Sweden
    Physiol Rev 81:1535-65. 2001
    ....
  4. pmc Estrogen receptors alpha and beta in the rodent mammary gland
    S Saji
    Department of Medical Nutrition, Karolinska Institute, Novum, S 141 86 Huddinge, Sweden
    Proc Natl Acad Sci U S A 97:337-42. 2000
    ....
  5. ncbi Quantitative analysis of estrogen receptor proteins in rat mammary gland
    S Saji
    Department of Medical Nutrition, Karolinska Institute, Novum, S141-86 Huddinge, Sweden
    Endocrinology 142:3177-86. 2001
    ....
  6. ncbi Mechanism of oestrogen signalling with particular reference to the role of ER beta in the central nervous system
    E Treuter
    Karolinska Institutet, Department of Biosciences at Novum, Huddinge, Sweden
    Novartis Found Symp 230:7-14; discussion 15-9. 2000
    ..The CNS contains both ER alpha and ER beta and it is conceivable that they may have specific and individual roles in oestrogen signalling in the brain...
  7. doi Spatiotemporal dynamics of the expression of estrogen receptors in the postnatal mouse brain
    N Sugiyama
    Department of Biosciences and Nutrition, Karolinska Institute, Novum, Huddinge, Sweden
    Mol Psychiatry 14:223-32, 117. 2009
    ..In addition, the importance of aromatase has to be reconsidered as the alternative estrogen, 3betaAdiol, is important in neuronal function in the postnatal brain...
  8. ncbi Identification of CYP2A3 as a major cytochrome P450 enzyme in the female peripubertal rat breast
    H Hellmold
    Department of Medical Nutrition, Karolinska Institute, Novum, S 141 86 Huddinge, Sweden
    Mol Pharmacol 53:475-82. 1998
    ..The peripubertal period seems to be a window in time when the breast may be more sensitive to procarcinogens that are substrates for CYP2A3...
  9. pmc Estrogen receptors and proliferation markers in primary and recurrent breast cancer
    E V Jensen
    Departments of Medical Nutrition and Biosciences, Karolinska Institute, Novum, S-141 86 Huddinge, Sweden
    Proc Natl Acad Sci U S A 98:15197-202. 2001
    ..Thus, appropriate ERbeta-specific ligands, perhaps in combination with tamoxifen, may be useful in improving the treatment of breast cancers...
  10. doi Biological functions and clinical implications of oestrogen receptors alfa and beta in epithelial tissues
    A Morani
    From the Departments of Biosciences and Nutrition, Karolinska Institutet, Novum, Huddinge, Sweden
    J Intern Med 264:128-42. 2008
    ..These pharmaceuticals are likely to be of clinical importance in the prevention or treatment of various diseases...
  11. ncbi Regional distribution of cytochrome P-450 in the rat brain: spectral quantitation and contribution of P-450b,e, and P-450c,d
    M Warner
    Department of Medical Nutrition, Karolinska Institute, Huddinge University Hospital, Sweden
    J Neurochem 50:1057-65. 1988
    ..There was no staining of Purkinje cells. In the thalamus, anti-P-450b gave weak staining of certain astroglia, but with anti-P-450c, there was intense staining of neuronal somata.(ABSTRACT TRUNCATED AT 250 WORDS)..
  12. ncbi The normal and malignant mammary gland: a fresh look with ER beta onboard
    M Warner
    Department of Bioscience, Karolinska Institute, Novum, Huddinge, Sweden
    J Mammary Gland Biol Neoplasia 5:289-94. 2000
    ..In many cell systems ER beta has actions which are opposite to those of ER alpha and this finding has raised questions about the role of ER beta in the development and treatment of breast cancer...