Research Topics
Species | Hui Xin WangSummaryAffiliation: Karolinska Institutet Country: Sweden Publications
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Detail Information
Publications
Influence of social support on progression of coronary artery disease in womenHui Xin Wang
Department of Public Health Sciences, Karolinska Institute, P O Box 220, 171 77 Stockholm, Sweden
Soc Sci Med 60:599-607. 2005..The results of our study suggest that lack of emotional support, social isolation, and lack of interpersonal social relations are important risk factors for accelerated progression of coronary atherosclerosis in middle-aged women...- Vitamin B(12) and folate in relation to the development of Alzheimer's diseaseH X Wang
Stockholm Gerontology Research Center and Division of Geriatric Medicine, Neurotec, Karolinska Institutet, Stockholm
Neurology 56:1188-94. 2001..To explore the associations of low serum levels of vitamin B(12) and folate with AD occurrence... - Late-life engagement in social and leisure activities is associated with a decreased risk of dementia: a longitudinal study from the Kungsholmen projectHui Xin Wang
Aging Research Center, Division of Geriatric Epidemiology and Medicine, Neurotec, Karolinska Institutet, and Stockholm Gerontology Research Center, Stockholm, Sweden
Am J Epidemiol 155:1081-7. 2002.... 
Lifestyle, social factors, and survival after age 75: population based studyDebora Rizzuto
Aging Research Center, Department of Neurobiology, Health Care Sciences and Society, Karolinska Institutet and Stockholm University, 113 30 Stockholm, Sweden
BMJ 345:e5568. 2012..To identify modifiable factors associated with longevity among adults aged 75 and older...
Psychosocial stress at work is associated with increased dementia risk in late lifeHui Xin Wang
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Sweden
Alzheimers Dement 8:114-20. 2012..To test the hypothesis that high job stress during working life might lead to an increased risk of dementia and Alzheimer's disease (AD) in late life...- Mental, physical and social components in leisure activities equally contribute to decrease dementia riskAnita Karp
Aging Research Center, Division of Geriatric Epidemiology, Department of Neurotec, Karolinska Institutet, Stockholm, Sweden
Dement Geriatr Cogn Disord 21:65-73. 2006..Since many activities contain more than one component, we aimed to verify the effect of all three major components on the dementia risk, as well as their combined effect... - The obesity related gene, FTO, interacts with APOE, and is associated with Alzheimer's disease risk: a prospective cohort studyLina Keller
Aging Research Center, Department NVS, Karolinska Institutet and Stockholm University, Stockholm, Sweden
J Alzheimers Dis 23:461-9. 2011..Our results are in line with the recently reported association between FTO and reduced brain volume in cognitively healthy subjects... - Mentally stimulating activities at work during midlife and dementia risk after age 75: follow-up study from the Kungsholmen ProjectAnita Karp
Aging Research Center, Karolinska Institutet, and the Stockholm Gerontology Research Center, Gavlegatan 16, Stockholm, Sweden
Am J Geriatr Psychiatry 17:227-36. 2009..This study aimed to explore the association between work complexity factors at midlife and dementia risk in late life under the hypothesis that high work complexity may modulate the increased dementia risk due to low education... - Brain reserve hypothesis in dementiaLaura Fratiglioni
Aging Research Center, Department NVS, Karolinska Institute, and Stockholm Gerontology Research Center, Stockholm, Sweden
J Alzheimers Dis 12:11-22. 2007..Delaying dementia onset by five years would halve dementia prevalence and substantially decrease the number of dementia cases in the community... - Accelerated progression from mild cognitive impairment to dementia in people with diabetesWeili Xu
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
Diabetes 59:2928-35. 2010..We sought to examine whether diabetes and pre-diabetes are associated with MCI and accelerate the progression from MCI to dementia... - Patterns of chronic multimorbidity in the elderly populationAlessandra Marengoni
Aging Research Center, Department of Neurobiology, Karolinska Institutet, Stockholm, Sweden
J Am Geriatr Soc 57:225-30. 2009..To describe patterns of comorbidity and multimorbidity in elderly people... - Stress reduction prolongs life in women with coronary disease: the Stockholm Women's Intervention Trial for Coronary Heart Disease (SWITCHD)Kristina Orth-Gomer
Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden
Circ Cardiovasc Qual Outcomes 2:25-32. 2009..Interventions that counteract women's psychosocial stress have not previously been presented. This study implemented a stress reduction program for women and investigated its ability to improve survival in women coronary patients... - Education halves the risk of dementia due to apolipoprotein ε4 allele: a collaborative study from the Swedish brain power initiativeHui Xin Wang
Aging Research Center, Department of Neurobiology, Caring Sciences, and Society, Karolinska Institutet, Stockholm, Sweden
Neurobiol Aging 33:1007.e1-7. 2012.... - APOE-related mortality: effect of dementia, cardiovascular disease and genderLina Rosvall
Aging Research Center, Karolinska Institutet and Stockholm Gerontology Research Center, SE 11330, Stockholm, Sweden
Neurobiol Aging 30:1545-51. 2009..These findings suggest different roles for the APOE alleles in survival by gender in old age... - A functional polymorphism in the HMGCR promoter affects transcriptional activity but not the risk for Alzheimer disease in Swedish populationsLina Keller
Department NVS, KI Alzheimer Disease Research Center, Karolinska Institutet, Huddinge, SE 14157 Stockholm, Sweden
Brain Res 1344:185-91. 2010..03; 95% CI=0.72-1.48). However, we did find evidence supporting an interaction between the HMGCR A allele, the APOE E4 allele and an altered risk of AD (OR=2.41; 95% CI=0.93-6.22)... - Accelerated Progression from Mild Cognitive Impairment to Dementia Among APOE ε4ε4 CarriersWei Li Xu
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden Department of Epidemiology, Tianjin Medical University, Tianjin, China
J Alzheimers Dis 33:507-15. 2013..The ε4 homozygote substantially accelerates progression from MCI to dementia, and anticipate dementia occurrence by more than 3 years in people with MCI... - An active lifestyle postpones dementia onset by more than one year in very old adultsStephanie Paillard-Borg
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
J Alzheimers Dis 31:835-42. 2012..These findings highlight the relevance of encouraging old adults to have active lifestyles, which could have a great impact on public health... - Leisure activities, cognition and dementiaHui Xin Wang
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Gavlegatan 16, 113 30 Stockholm, Sweden
Biochim Biophys Acta 1822:482-91. 2012..Further, well designed studies with long follow-up times are necessary. This article is part of a Special Issue entitled: Imaging Brain Aging and Neurodegenerative disease... - [Who can manage until the age of 65? Not the women--more than a half of all women stop working prematurely]Kristina Orth-Gomer
Institutionen för folkhälsovetenskap, Karolinska Institutet, Stockholm
Lakartidningen 102:2296-9, 2301, 2302-3. 2005..To stop working before the age of 65, with or without economic compensation, may be interpreted as an effective "coping-mechanism" available to well educated women, in order to avoid life-threatening illness... - Leisure activities in late life in relation to dementia risk: principal component analysisStephanie Paillard-Borg
Aging Research Center ARC, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
Dement Geriatr Cogn Disord 28:136-44. 2009..To explore the underlying dimensions of a set of interrelated lifestyle factors and test the hypothesis that an active lifestyle may protect against dementia... - How can elderly apolipoprotein E ε4 carriers remain free from dementia?Camilla Ferrari
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden Department of Neurological and Psychiatric Sciences, University of Florence, Florence, Italy
Neurobiol Aging 34:13-21. 2013..The ε4 carriers with these characteristics appear to have similar dementia-free survival time to non-ε4 carriers... - Depressive symptoms, social isolation, and progression of coronary artery atherosclerosis: the Stockholm Female Coronary Angiography StudyHui-Xin Wang
Division of Preventive Medicine, Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden
Psychother Psychosom 75:96-102. 2006..These findings provide an additional opportunity for therapeutic and preventive efforts against progression of coronary disease in women... - Differential evolution of cognitive impairment in nondemented older persons: results from the Kungsholmen ProjectKatie Palmer
Stockholm Gerontology Research Center and Division of Geriatric Epidemiology, Department of Clinical Neuroscience, Occupational Therapy and Elderly Care Research, Uppsala University, Sweden
Am J Psychiatry 159:436-42. 2002..This study was a prospective, population-based examination of the evolution of cognitive impairment, no dementia (CIND)...