Hui Xin Wang

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Influence of social support on progression of coronary artery disease in women
    Hui Xin Wang
    Department of Public Health Sciences, Karolinska Institute, P O Box 220, 171 77 Stockholm, Sweden
    Soc Sci Med 60:599-607. 2005
  2. ncbi request reprint Vitamin B(12) and folate in relation to the development of Alzheimer's disease
    H X Wang
    Stockholm Gerontology Research Center and Division of Geriatric Medicine, Neurotec, Karolinska Institutet, Stockholm
    Neurology 56:1188-94. 2001
  3. ncbi request reprint Late-life engagement in social and leisure activities is associated with a decreased risk of dementia: a longitudinal study from the Kungsholmen project
    Hui Xin Wang
    Aging Research Center, Division of Geriatric Epidemiology and Medicine, Neurotec, Karolinska Institutet, and Stockholm Gerontology Research Center, Stockholm, Sweden
    Am J Epidemiol 155:1081-7. 2002
  4. doi request reprint How can elderly apolipoprotein E ε4 carriers remain free from dementia?
    Camilla Ferrari
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    Neurobiol Aging 34:13-21. 2013
  5. doi request reprint Accelerated progression from mild cognitive impairment to dementia among APOE ε4ε4 carriers
    Wei Li Xu
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 33:507-15. 2013
  6. doi request reprint An active lifestyle postpones dementia onset by more than one year in very old adults
    Stephanie Paillard-Borg
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 31:835-42. 2012
  7. doi request reprint Psychosocial stress at work is associated with increased dementia risk in late life
    Hui Xin Wang
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Sweden
    Alzheimers Dement 8:114-20. 2012
  8. pmc Lifestyle, social factors, and survival after age 75: population based study
    Debora Rizzuto
    Aging Research Center, Department of Neurobiology, Health Care Sciences and Society, Karolinska Institutet and Stockholm University, 113 30 Stockholm, Sweden
    BMJ 345:e5568. 2012
  9. doi request reprint The obesity related gene, FTO, interacts with APOE, and is associated with Alzheimer's disease risk: a prospective cohort study
    Lina Keller
    Aging Research Center, Department NVS, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 23:461-9. 2011
  10. doi request reprint Mentally stimulating activities at work during midlife and dementia risk after age 75: follow-up study from the Kungsholmen Project
    Anita Karp
    Aging Research Center, Karolinska Institutet, and the Stockholm Gerontology Research Center, Gavlegatan 16, Stockholm, Sweden
    Am J Geriatr Psychiatry 17:227-36. 2009

Detail Information

Publications26

  1. ncbi request reprint Influence of social support on progression of coronary artery disease in women
    Hui Xin Wang
    Department of Public Health Sciences, Karolinska Institute, P O Box 220, 171 77 Stockholm, Sweden
    Soc Sci Med 60:599-607. 2005
    ..The results of our study suggest that lack of emotional support, social isolation, and lack of interpersonal social relations are important risk factors for accelerated progression of coronary atherosclerosis in middle-aged women...
  2. ncbi request reprint Vitamin B(12) and folate in relation to the development of Alzheimer's disease
    H X Wang
    Stockholm Gerontology Research Center and Division of Geriatric Medicine, Neurotec, Karolinska Institutet, Stockholm
    Neurology 56:1188-94. 2001
    ..To explore the associations of low serum levels of vitamin B(12) and folate with AD occurrence...
  3. ncbi request reprint Late-life engagement in social and leisure activities is associated with a decreased risk of dementia: a longitudinal study from the Kungsholmen project
    Hui Xin Wang
    Aging Research Center, Division of Geriatric Epidemiology and Medicine, Neurotec, Karolinska Institutet, and Stockholm Gerontology Research Center, Stockholm, Sweden
    Am J Epidemiol 155:1081-7. 2002
    ....
  4. doi request reprint How can elderly apolipoprotein E ε4 carriers remain free from dementia?
    Camilla Ferrari
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    Neurobiol Aging 34:13-21. 2013
    ..The ε4 carriers with these characteristics appear to have similar dementia-free survival time to non-ε4 carriers...
  5. doi request reprint Accelerated progression from mild cognitive impairment to dementia among APOE ε4ε4 carriers
    Wei Li Xu
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 33:507-15. 2013
    ..The ε4 homozygote substantially accelerates progression from MCI to dementia, and anticipate dementia occurrence by more than 3 years in people with MCI...
  6. doi request reprint An active lifestyle postpones dementia onset by more than one year in very old adults
    Stephanie Paillard-Borg
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 31:835-42. 2012
    ..These findings highlight the relevance of encouraging old adults to have active lifestyles, which could have a great impact on public health...
  7. doi request reprint Psychosocial stress at work is associated with increased dementia risk in late life
    Hui Xin Wang
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Sweden
    Alzheimers Dement 8:114-20. 2012
    ..To test the hypothesis that high job stress during working life might lead to an increased risk of dementia and Alzheimer's disease (AD) in late life...
  8. pmc Lifestyle, social factors, and survival after age 75: population based study
    Debora Rizzuto
    Aging Research Center, Department of Neurobiology, Health Care Sciences and Society, Karolinska Institutet and Stockholm University, 113 30 Stockholm, Sweden
    BMJ 345:e5568. 2012
    ..To identify modifiable factors associated with longevity among adults aged 75 and older...
  9. doi request reprint The obesity related gene, FTO, interacts with APOE, and is associated with Alzheimer's disease risk: a prospective cohort study
    Lina Keller
    Aging Research Center, Department NVS, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 23:461-9. 2011
    ..Our results are in line with the recently reported association between FTO and reduced brain volume in cognitively healthy subjects...
  10. doi request reprint Mentally stimulating activities at work during midlife and dementia risk after age 75: follow-up study from the Kungsholmen Project
    Anita Karp
    Aging Research Center, Karolinska Institutet, and the Stockholm Gerontology Research Center, Gavlegatan 16, Stockholm, Sweden
    Am J Geriatr Psychiatry 17:227-36. 2009
    ..This study aimed to explore the association between work complexity factors at midlife and dementia risk in late life under the hypothesis that high work complexity may modulate the increased dementia risk due to low education...
  11. ncbi request reprint Mental, physical and social components in leisure activities equally contribute to decrease dementia risk
    Anita Karp
    Aging Research Center, Division of Geriatric Epidemiology, Department of Neurotec, Karolinska Institutet, Stockholm, Sweden
    Dement Geriatr Cogn Disord 21:65-73. 2006
    ..Since many activities contain more than one component, we aimed to verify the effect of all three major components on the dementia risk, as well as their combined effect...
  12. pmc Late life leisure activities and risk of cognitive decline
    Hui Xin Wang
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Gavlegatan 16, 113 30 Stockholm, Sweden
    J Gerontol A Biol Sci Med Sci 68:205-13. 2013
    ..This study tests the hypothesis that mental, physical, and social activities have a domain-specific protection against cognitive decline...
  13. ncbi request reprint Brain reserve hypothesis in dementia
    Laura Fratiglioni
    Aging Research Center, Department NVS, Karolinska Institute, and Stockholm Gerontology Research Center, Stockholm, Sweden
    J Alzheimers Dis 12:11-22. 2007
    ..Delaying dementia onset by five years would halve dementia prevalence and substantially decrease the number of dementia cases in the community...
  14. ncbi request reprint Depressive symptoms, social isolation, and progression of coronary artery atherosclerosis: the Stockholm Female Coronary Angiography Study
    Hui Xin Wang
    Division of Preventive Medicine, Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden
    Psychother Psychosom 75:96-102. 2006
    ..Although both depressive symptoms and social isolation in relation to coronary heart disease have been studied previously, few have examined their joint effects on coronary atherosclerosis progression in women...
  15. pmc Accelerated progression from mild cognitive impairment to dementia in people with diabetes
    Weili Xu
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    Diabetes 59:2928-35. 2010
    ..We sought to examine whether diabetes and pre-diabetes are associated with MCI and accelerate the progression from MCI to dementia...
  16. doi request reprint Stress reduction prolongs life in women with coronary disease: the Stockholm Women's Intervention Trial for Coronary Heart Disease (SWITCHD)
    Kristina Orth-Gomer
    Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden
    Circ Cardiovasc Qual Outcomes 2:25-32. 2009
    ..Interventions that counteract women's psychosocial stress have not previously been presented. This study implemented a stress reduction program for women and investigated its ability to improve survival in women coronary patients...
  17. doi request reprint Patterns of chronic multimorbidity in the elderly population
    Alessandra Marengoni
    Aging Research Center, Department of Neurobiology, Karolinska Institutet, Stockholm, Sweden
    J Am Geriatr Soc 57:225-30. 2009
    ..To describe patterns of comorbidity and multimorbidity in elderly people...
  18. doi request reprint Lifestyle change and the prevention of cognitive decline and dementia: what is the evidence?
    Martin Lövdén
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    Curr Opin Psychiatry 26:239-43. 2013
    ..Much recent research has, therefore, adopted an interventional focus. We review this work, highlight some methodological limitations, and provide recommendations for future research...
  19. doi request reprint Education halves the risk of dementia due to apolipoprotein ε4 allele: a collaborative study from the Swedish brain power initiative
    Hui Xin Wang
    Aging Research Center, Department of Neurobiology, Caring Sciences, and Society, Karolinska Institutet, Stockholm, Sweden
    Neurobiol Aging 33:1007.e1-7. 2012
    ....
  20. doi request reprint A functional polymorphism in the HMGCR promoter affects transcriptional activity but not the risk for Alzheimer disease in Swedish populations
    Lina Keller
    Department NVS, KI Alzheimer Disease Research Center, Karolinska Institutet, Huddinge, SE 14157 Stockholm, Sweden
    Brain Res 1344:185-91. 2010
    ..03; 95% CI=0.72-1.48). However, we did find evidence supporting an interaction between the HMGCR A allele, the APOE E4 allele and an altered risk of AD (OR=2.41; 95% CI=0.93-6.22)...
  21. doi request reprint APOE-related mortality: effect of dementia, cardiovascular disease and gender
    Lina Rosvall
    Aging Research Center, Karolinska Institutet and Stockholm Gerontology Research Center, SE 11330, Stockholm, Sweden
    Neurobiol Aging 30:1545-51. 2009
    ..These findings suggest different roles for the APOE alleles in survival by gender in old age...
  22. doi request reprint Leisure activities, cognition and dementia
    Hui Xin Wang
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Gavlegatan 16, 113 30 Stockholm, Sweden
    Biochim Biophys Acta 1822:482-91. 2012
    ..Further, well designed studies with long follow-up times are necessary. This article is part of a Special Issue entitled: Imaging Brain Aging and Neurodegenerative disease...
  23. doi request reprint Leisure activities in late life in relation to dementia risk: principal component analysis
    Stephanie Paillard-Borg
    Aging Research Center ARC, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
    Dement Geriatr Cogn Disord 28:136-44. 2009
    ..To explore the underlying dimensions of a set of interrelated lifestyle factors and test the hypothesis that an active lifestyle may protect against dementia...
  24. ncbi request reprint [Who can manage until the age of 65? Not the women--more than a half of all women stop working prematurely]
    Kristina Orth-Gomer
    Institutionen för folkhälsovetenskap, Karolinska Institutet, Stockholm
    Lakartidningen 102:2296-9, 2301, 2302-3. 2005
    ..To stop working before the age of 65, with or without economic compensation, may be interpreted as an effective "coping-mechanism" available to well educated women, in order to avoid life-threatening illness...
  25. pmc Is Midlife Occupational Physical Activity Related to Disability in Old Age? The SNAC-Kungsholmen Study
    Elisabeth Rydwik
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden Research and Development Unit, Jakobsbergs Hospital, Stockholm County Council, Järfälla, Sweden
    PLoS ONE 8:e70471. 2013
    ....
  26. ncbi request reprint Differential evolution of cognitive impairment in nondemented older persons: results from the Kungsholmen Project
    Katie Palmer
    Stockholm Gerontology Research Center and Division of Geriatric Epidemiology, Department of Clinical Neuroscience, Occupational Therapy and Elderly Care Research, Uppsala University, Sweden
    Am J Psychiatry 159:436-42. 2002
    ..This study was a prospective, population-based examination of the evolution of cognitive impairment, no dementia (CIND)...