Nils Wahlgren

Summary

Affiliation: Karolinska University Hospital
Country: Sweden

Publications

  1. doi request reprint Thrombolysis with alteplase 3-4.5 h after acute ischaemic stroke (SITS-ISTR): an observational study
    Nils Wahlgren
    Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden
    Lancet 372:1303-9. 2008
  2. ncbi request reprint Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study
    Nils Wahlgren
    Department of Neurology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
    Lancet 369:275-82. 2007
  3. doi request reprint Systemic thrombolysis in clinical practice: what have we learned after the Safe Implementation of Thrombolysis in Stroke Monitoring Study?
    Nils Wahlgren
    Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden
    Cerebrovasc Dis 27:168-76. 2009
  4. doi request reprint Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST)
    Nils Wahlgren
    Department of Neurology, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, Sweden
    Stroke 39:3316-22. 2008
  5. doi request reprint Predicting the risk of symptomatic intracerebral hemorrhage in ischemic stroke treated with intravenous alteplase: safe Implementation of Treatments in Stroke (SITS) symptomatic intracerebral hemorrhage risk score
    Michael Mazya
    Department of Neurology, Karolinska University Hospital Solna, Karolinska Stroke Research, Stockholm, Sweden
    Stroke 43:1524-31. 2012
  6. doi request reprint Association of admission blood glucose and outcome in patients treated with intravenous thrombolysis: results from the Safe Implementation of Treatments in Stroke International Stroke Thrombolysis Register (SITS-ISTR)
    Niaz Ahmed
    Karolinska Stroke Research Unit, Department of Neurology, Karolinska University Hospital Solna, Stockholm, Sweden
    Arch Neurol 67:1123-30. 2010
  7. doi request reprint Within-day and weekly variations of thrombolysis in acute ischemic stroke: results from safe implementation of treatments in stroke-international stroke thrombolysis register
    Svetlana Lorenzano
    From the Emergency Department Stroke Unit, Department of Neurology and Psychiatry, Policlinico Umberto I Hospital, Sapienza University of Rome, Rome, Italy S L, D T Karolinska Stroke Research Unit, Department of Neurology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden N A, N W Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland T T Acute Stroke Unit, Department of Neuroscience, Hospital Universitari Germas Trias i Pujol, Universidad Autonoma de Barcelona, Barcelona, Spain M G, A D International Clinical Research Center, Neurology Department, St Anne s Hospital, Brno, Czech Republic R M Department of Neurology, University Hospital, Plzen, Czech Republic P S and Department of Neurology and Rehabilitation, Tampere University Hospital, Tampere, Finland J O
    Stroke 45:176-84. 2014
  8. doi request reprint Implementation and outcome of thrombolysis with alteplase 3-4.5 h after an acute stroke: an updated analysis from SITS-ISTR
    Niaz Ahmed
    Department of Neurology, Karolinska University Hospital, and Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden
    Lancet Neurol 9:866-74. 2010
  9. doi request reprint Does sex influence the response to intravenous thrombolysis in ischemic stroke?: answers from safe implementation of treatments in Stroke-International Stroke Thrombolysis Register
    Svetlana Lorenzano
    From the Emergency Department Stroke Unit, Department of Neurology and Psychiatry, Policlinico Umberto I Hospital, Sapienza University of Rome, Rome, Italy S L, A F, D T Karolinska Stroke Research Unit, Department of Neurology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden N A, N W International Clinical Research Center, Neurology Department, St Anne s Hospital, Brno, Czech Republic R M Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland T T and Stroke Research Offices, Royal Infirmary, Keele University, North Staffordshire, United Kingdom C R
    Stroke 44:3401-6. 2013
  10. doi request reprint Importance of cerebral artery recanalization in patients with stroke with and without neurological improvement after intravenous thrombolysis
    Tatiana V Kharitonova
    Department of Neurology, Karolinska University Hospital, Stockholm, Sweden
    Stroke 44:2513-8. 2013

Collaborators

Detail Information

Publications18

  1. doi request reprint Thrombolysis with alteplase 3-4.5 h after acute ischaemic stroke (SITS-ISTR): an observational study
    Nils Wahlgren
    Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden
    Lancet 372:1303-9. 2008
    ..5 h versus those treated within 3 h, who were recorded in the in the Safe Implementation of Treatments in Stroke (SITS), a prospective internet-based audit of the International Stroke Thrombolysis Registry (ISTR)...
  2. ncbi request reprint Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study
    Nils Wahlgren
    Department of Neurology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
    Lancet 369:275-82. 2007
    ..Under European Union regulations, SITS-MOST was required to assess the safety profile of alteplase in clinical practice by comparison with results in randomised controlled trials...
  3. doi request reprint Systemic thrombolysis in clinical practice: what have we learned after the Safe Implementation of Thrombolysis in Stroke Monitoring Study?
    Nils Wahlgren
    Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden
    Cerebrovasc Dis 27:168-76. 2009
    ..Important information is currently collected on the effect on door-to-needle time and safety of a broad implementation of thrombolysis in a later time window...
  4. doi request reprint Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST)
    Nils Wahlgren
    Department of Neurology, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, Sweden
    Stroke 39:3316-22. 2008
    ..We aimed to identify outcome predictors and adjust the outcomes of the SITS-MOST to the baseline characteristics of RCTs...
  5. doi request reprint Predicting the risk of symptomatic intracerebral hemorrhage in ischemic stroke treated with intravenous alteplase: safe Implementation of Treatments in Stroke (SITS) symptomatic intracerebral hemorrhage risk score
    Michael Mazya
    Department of Neurology, Karolinska University Hospital Solna, Karolinska Stroke Research, Stockholm, Sweden
    Stroke 43:1524-31. 2012
    ..Symptomatic intracerebral hemorrhage (SICH) is a serious complication in patients with acute ischemic stroke treated with intravenous thrombolysis. We aimed to develop a clinical score that can easily be applied to predict the risk of SICH...
  6. doi request reprint Association of admission blood glucose and outcome in patients treated with intravenous thrombolysis: results from the Safe Implementation of Treatments in Stroke International Stroke Thrombolysis Register (SITS-ISTR)
    Niaz Ahmed
    Karolinska Stroke Research Unit, Department of Neurology, Karolinska University Hospital Solna, Stockholm, Sweden
    Arch Neurol 67:1123-30. 2010
    ..To determine the association between admission blood glucose and outcome in ischemic stroke patients treated with thrombolysis...
  7. doi request reprint Within-day and weekly variations of thrombolysis in acute ischemic stroke: results from safe implementation of treatments in stroke-international stroke thrombolysis register
    Svetlana Lorenzano
    From the Emergency Department Stroke Unit, Department of Neurology and Psychiatry, Policlinico Umberto I Hospital, Sapienza University of Rome, Rome, Italy S L, D T Karolinska Stroke Research Unit, Department of Neurology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden N A, N W Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland T T Acute Stroke Unit, Department of Neuroscience, Hospital Universitari Germas Trias i Pujol, Universidad Autonoma de Barcelona, Barcelona, Spain M G, A D International Clinical Research Center, Neurology Department, St Anne s Hospital, Brno, Czech Republic R M Department of Neurology, University Hospital, Plzen, Czech Republic P S and Department of Neurology and Rehabilitation, Tampere University Hospital, Tampere, Finland J O
    Stroke 45:176-84. 2014
    ..In this large cohort study, we evaluated whether thrombolytic treatment has a within-day and weekly variability corresponding to circadian and weekly patterns of ischemic stroke onset, and whether these have impact on clinical outcome...
  8. doi request reprint Implementation and outcome of thrombolysis with alteplase 3-4.5 h after an acute stroke: an updated analysis from SITS-ISTR
    Niaz Ahmed
    Department of Neurology, Karolinska University Hospital, and Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden
    Lancet Neurol 9:866-74. 2010
    ..5 h after stroke onset. We aimed to assess the implementation of the wider time window, its effect on the admission-to-treatment time, and safety and functional outcome in patients recorded in SITS-ISTR...
  9. doi request reprint Does sex influence the response to intravenous thrombolysis in ischemic stroke?: answers from safe implementation of treatments in Stroke-International Stroke Thrombolysis Register
    Svetlana Lorenzano
    From the Emergency Department Stroke Unit, Department of Neurology and Psychiatry, Policlinico Umberto I Hospital, Sapienza University of Rome, Rome, Italy S L, A F, D T Karolinska Stroke Research Unit, Department of Neurology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden N A, N W International Clinical Research Center, Neurology Department, St Anne s Hospital, Brno, Czech Republic R M Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland T T and Stroke Research Offices, Royal Infirmary, Keele University, North Staffordshire, United Kingdom C R
    Stroke 44:3401-6. 2013
    ..We aimed to evaluate differences in 3-month outcome between sexes in intravenous tissue-type plasminogen activator-treated patients registered in the Safe Implementation of Treatments in Stroke-International Stroke Thrombolysis Register...
  10. doi request reprint Importance of cerebral artery recanalization in patients with stroke with and without neurological improvement after intravenous thrombolysis
    Tatiana V Kharitonova
    Department of Neurology, Karolinska University Hospital, Stockholm, Sweden
    Stroke 44:2513-8. 2013
    ..We aimed to evaluate the importance of restoration of blood flow at the arterial occlusion site in subgroups of patients with stroke stratified by early NI after IVT...
  11. ncbi request reprint Relationship of blood pressure, antihypertensive therapy, and outcome in ischemic stroke treated with intravenous thrombolysis: retrospective analysis from Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTR
    Niaz Ahmed
    SITS International Coordination Office, Karolinska Stroke Research, Department of Neurology, Karolinska University Hospital Solna, Stockholm, Sweden
    Stroke 40:2442-9. 2009
    ..We determined retrospectively the association of BP and antihypertensive therapy with clinical outcomes after stroke thrombolysis...
  12. doi request reprint Disappearing hyperdense middle cerebral artery sign in ischaemic stroke patients treated with intravenous thrombolysis: clinical course and prognostic significance
    T Kharitonova
    Department of Neurology, Karolinska University Hospital Solna, SE 171 76 Stockholm, Sweden
    J Neurol Neurosurg Psychiatry 80:273-8. 2009
    ..Its disappearance after thrombolytic therapy is poorly described. Taking the rate of HMCAS disappearance as a surrogate for MCA recanalisation, its prognostic value after intravenous thrombolysis was examined...
  13. doi request reprint External validation of the SEDAN score for prediction of intracerebral hemorrhage in stroke thrombolysis
    Michael V Mazya
    Department of Neurology, SITS International Coordination Office, Karolinska Stroke Research, Karolinska University Hospital, Solna, Stockholm 17176, Sweden
    Stroke 44:1595-600. 2013
    ..We assessed the performance of the score in predicting SICH per the ECASS II and Safe Implementation of Treatments in Stroke Monitoring Study (SITS-MOST) definitions in the SITS-International Stroke Thrombolysis Register (SITS-ISTR)...
  14. doi request reprint Association of early National Institutes of Health Stroke Scale improvement with vessel recanalization and functional outcome after intravenous thrombolysis in ischemic stroke
    Tatiana Kharitonova
    Karolinska Stroke Research Unit, Department of Neurology, Karolinska University Hospital, Sweden
    Stroke 42:1638-43. 2011
    ....
  15. ncbi request reprint Safety of intravenous thrombolysis for ischemic stroke in patients treated with warfarin
    Michael V Mazya
    Department of Neurology, Karolinska University Hospital and Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Ann Neurol 74:266-74. 2013
    ..7. The influence of warfarin on symptomatic intracerebral hemorrhage (SICH), arterial recanalization, and long-term functional outcome in stroke thrombolysis remains unclear...
  16. doi request reprint Hyperdense middle cerebral artery sign on admission CT scan--prognostic significance for ischaemic stroke patients treated with intravenous thrombolysis in the safe implementation of thrombolysis in Stroke International Stroke Thrombolysis Register
    Tatiana Kharitonova
    Department of Neurology, Karolinska Stroke Research Unit, SITS International Coordination Office, Karolinska University Hospital Solna, Stockholm, Sweden
    Cerebrovasc Dis 27:51-9. 2009
    ..Hyperdense middle cerebral artery sign (HMCAS) on CT scan before stroke thrombolysis is associated with increased risk for haemorrhage and unfavourable outcome in several small studies...
  17. doi request reprint Face arm speech time test use in the prehospital setting, better in the ambulance than in the emergency medical communication center
    Annika Berglund
    Karolinska Institutet Stroke Research Network at Södersjukhuset, Sodersjukhuset, Stockholm, Sweden
    Cerebrovasc Dis 37:212-6. 2014
    ..This substudy aims to evaluate the implementation of the FAST test in the EMCC and the ambulance service...
  18. ncbi request reprint Higher prehospital priority level of stroke improves thrombolysis frequency and time to stroke unit: the Hyper Acute STroke Alarm (HASTA) study
    Annika Berglund
    Karolinska Institutet, Department of Clinical Science and Education, Sodersjukhuset, 118 83 Stockholm, Sweden
    Stroke 43:2666-70. 2012
    ....