Research Topics
| Nils WahlgrenSummaryAffiliation: Karolinska University Hospital Country: Sweden Publications
| Collaborators
|
Detail Information
Publications
Thrombolysis with alteplase 3-4.5 h after acute ischaemic stroke (SITS-ISTR): an observational studyNils Wahlgren
Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden
Lancet 372:1303-9. 2008..5 h versus those treated within 3 h, who were recorded in the in the Safe Implementation of Treatments in Stroke (SITS), a prospective internet-based audit of the International Stroke Thrombolysis Registry (ISTR)...
Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational studyNils Wahlgren
Department of Neurology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
Lancet 369:275-82. 2007..Under European Union regulations, SITS-MOST was required to assess the safety profile of alteplase in clinical practice by comparison with results in randomised controlled trials...
Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST)Nils Wahlgren
Department of Neurology, Karolinska University Hospital Solna, Karolinska Institutet, Stockholm, Sweden
Stroke 39:3316-22. 2008..We aimed to identify outcome predictors and adjust the outcomes of the SITS-MOST to the baseline characteristics of RCTs...
Systemic thrombolysis in clinical practice: what have we learned after the Safe Implementation of Thrombolysis in Stroke Monitoring Study?Nils Wahlgren
Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden
Cerebrovasc Dis 27:168-76. 2009..Important information is currently collected on the effect on door-to-needle time and safety of a broad implementation of thrombolysis in a later time window...
Predicting the risk of symptomatic intracerebral hemorrhage in ischemic stroke treated with intravenous alteplase: safe Implementation of Treatments in Stroke (SITS) symptomatic intracerebral hemorrhage risk scoreMichael Mazya
Department of Neurology, Karolinska University Hospital Solna, Karolinska Stroke Research, Stockholm, Sweden
Stroke 43:1524-31. 2012..Symptomatic intracerebral hemorrhage (SICH) is a serious complication in patients with acute ischemic stroke treated with intravenous thrombolysis. We aimed to develop a clinical score that can easily be applied to predict the risk of SICH...
Association of admission blood glucose and outcome in patients treated with intravenous thrombolysis: results from the Safe Implementation of Treatments in Stroke International Stroke Thrombolysis Register (SITS-ISTR)Niaz Ahmed
Karolinska Stroke Research Unit, Department of Neurology, Karolinska University Hospital Solna, Stockholm, Sweden
Arch Neurol 67:1123-30. 2010..To determine the association between admission blood glucose and outcome in ischemic stroke patients treated with thrombolysis...
Implementation and outcome of thrombolysis with alteplase 3-4.5 h after an acute stroke: an updated analysis from SITS-ISTRNiaz Ahmed
Department of Neurology, Karolinska University Hospital, and Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden
Lancet Neurol 9:866-74. 2010..5 h after stroke onset. We aimed to assess the implementation of the wider time window, its effect on the admission-to-treatment time, and safety and functional outcome in patients recorded in SITS-ISTR...
Relationship of blood pressure, antihypertensive therapy, and outcome in ischemic stroke treated with intravenous thrombolysis: retrospective analysis from Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTRNiaz Ahmed
SITS International Coordination Office, Karolinska Stroke Research, Department of Neurology, Karolinska University Hospital Solna, Stockholm, Sweden
Stroke 40:2442-9. 2009..We determined retrospectively the association of BP and antihypertensive therapy with clinical outcomes after stroke thrombolysis...
Disappearing hyperdense middle cerebral artery sign in ischaemic stroke patients treated with intravenous thrombolysis: clinical course and prognostic significanceT Kharitonova
Department of Neurology, Karolinska University Hospital Solna, SE 171 76 Stockholm, Sweden
J Neurol Neurosurg Psychiatry 80:273-8. 2009..Its disappearance after thrombolytic therapy is poorly described. Taking the rate of HMCAS disappearance as a surrogate for MCA recanalisation, its prognostic value after intravenous thrombolysis was examined...
Association of early National Institutes of Health Stroke Scale improvement with vessel recanalization and functional outcome after intravenous thrombolysis in ischemic strokeTatiana Kharitonova
Karolinska Stroke Research Unit, Department of Neurology, Karolinska University Hospital, Sweden
Stroke 42:1638-43. 2011....
Hyperdense middle cerebral artery sign on admission CT scan--prognostic significance for ischaemic stroke patients treated with intravenous thrombolysis in the safe implementation of thrombolysis in Stroke International Stroke Thrombolysis RegisterTatiana Kharitonova
Department of Neurology, Karolinska Stroke Research Unit, SITS International Coordination Office, Karolinska University Hospital Solna, Stockholm, Sweden
Cerebrovasc Dis 27:51-9. 2009..Hyperdense middle cerebral artery sign (HMCAS) on CT scan before stroke thrombolysis is associated with increased risk for haemorrhage and unfavourable outcome in several small studies...
Higher prehospital priority level of stroke improves thrombolysis frequency and time to stroke unit: the Hyper Acute STroke Alarm (HASTA) studyAnnika Berglund
Karolinska Institutet, Department of Clinical Science and Education, Sodersjukhuset, 118 83 Stockholm, Sweden
Stroke 43:2666-70. 2012....
