Research Topics
| Marie E VahterSummaryAffiliation: Karolinska Institutet Country: Sweden Publications
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Detail Information
Publications
Relation between dietary cadmium intake and biomarkers of cadmium exposure in premenopausal women accounting for body iron storesBettina Julin
Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Environ Health 10:105. 2011..We aimed to assess the relationship between dietary cadmium intake assessed by analyses of duplicate food portions and cadmium concentrations in urine and blood, taking the toxicokinetics of cadmium into consideration...- Spatial patterns of fetal loss and infant death in an arsenic-affected area in BangladeshNazmul Sohel
Department of Women s and Children s Health, International Maternal and Child Health, Uppsala University, Uppsala, Sweden
Int J Health Geogr 9:53. 2010.... - Inter-individual variations of human mercury exposure biomarkers: a cross-sectional assessmentMarika Berglund
Department of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
Environ Health 4:20. 2005..We have evaluated the most frequently used biomarkers and the physiology on which they are based, to explore the inter-individual variations and their suitability for exposure assessment... 
Arsenic exposure in pregnancy: a population-based study in Matlab, BangladeshMarie E Vahter
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
J Health Popul Nutr 24:236-45. 2006..There were marked geographical variations in exposure. The results emphasize the urgent need for efficient mitigation activities and investigations of arsenic-related reproductive effects...- Interactions between arsenic-induced toxicity and nutrition in early lifeMarie E Vahter
Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden
J Nutr 137:2798-804. 2007..A third mode of arsenic-nutrition interaction involves epigenetic effects and fetal programming via DNA methylation... 
Health effects of early life exposure to arsenicMarie Vahter
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Basic Clin Pharmacol Toxicol 102:204-11. 2008....- Influence of iron and zinc status on cadmium accumulation in Bangladeshi womenMaria Kippler
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Toxicol Appl Pharmacol 222:221-6. 2007..In conclusion, low iron stores were associated with increased cadmium accumulation, but only at adequate zinc status... - Persistent exposure to arsenic via drinking water in rural Bangladesh despite major mitigation effortsRenee Gardner
Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
Am J Public Health 101:S333-8. 2011..We evaluated the effectiveness of long-term mitigation efforts by longitudinally measuring arsenic exposure in pregnant women and their children, the most susceptible population groups... - Effects of arsenic on maternal and fetal healthMarie Vahter
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Annu Rev Nutr 29:381-99. 2009..Early-life exposure may induce changes that will become apparent much later in life... - Breast-feeding protects against arsenic exposure in Bangladeshi infantsBritta Fängström
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Environ Health Perspect 116:963-9. 2008..Arsenic readily crosses the placenta, but the few available data on postnatal exposure to arsenic via breast milk are not conclusive... - Inorganic mercury and methylmercury in placentas of Swedish womenKarolin Ask
Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Environ Health Perspect 110:523-6. 2002..We found no correlations between I-Hg and selenium. This study increases the understanding of Hg, in its different forms, in human placenta and how they are related to maternal and fetal exposure... - Urinary arsenic concentration adjustment factors and malnutritionBarbro Nermell
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Environ Res 106:212-8. 2008..Furthermore, urinary creatinine was found to be significantly associated with urinary arsenic, which further disqualifies the creatinine adjustment... - Impaired arsenic metabolism in children during weaningBritta Fängström
Institute of Environmental Medicine, Karolinska Institutet, Box 210, 17177 Stockholm, Sweden
Toxicol Appl Pharmacol 239:208-14. 2009..Methylation of inorganic arsenic (iAs) via one-carbon metabolism is a susceptibility factor for a range of arsenic-related health effects, but there is no data on the importance of arsenic metabolism for effects on child development... - Nutritional status has marginal influence on the metabolism of inorganic arsenic in pregnant Bangladeshi womenLi Li
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Environ Health Perspect 116:315-21. 2008..The interindividual variation in metabolism of inorganic arsenic (iAs), involving methylation via one-carbon metabolism, has been well documented, but the reasons remain unclear... - Gender and age differences in the metabolism of inorganic arsenic in a highly exposed population in BangladeshAnna Lena Lindberg
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Environ Res 106:110-20. 2008..Overall, exposure level of arsenic, gender and age explained at most 30% of the variation in the present study, indicating that genetic polymorphisms are the most important factor influencing the metabolism of inorganic arsenic... - The risk of arsenic induced skin lesions in Bangladeshi men and women is affected by arsenic metabolism and the age at first exposureAnna Lena Lindberg
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Toxicol Appl Pharmacol 230:9-16. 2008..Thus, it can be speculated that this is due to a programming effect of arsenic in utero... - Neurobehavioural and molecular changes induced by methylmercury exposure during developmentCarolina Johansson
Division of Toxicology and Neurotoxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Neurotox Res 11:241-60. 2007..This review summarises what is currently known about the neurodevelopmental effects of MeHg and consider the strength of different experimental approaches to study the effects of environmentally relevant exposure in vivo and in vitro... - Concentrations of biomarkers in spot urine samples need adjustment for variation in dilution--Comment on: "Distribution of urinary selenium and arsenic among pregnant women exposed to arsenic in drinking water" [Environ Res. 2006;100(1):115-122]Marie Vahter
Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE-171 77 Stockholm, Sweden
Environ Res 104:312-3; discussion 314. 2007 - Methyl mercury exposure in Swedish women with high fish consumptionKarolin Ask Björnberg
Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77, Stockholm, Sweden
Sci Total Environ 341:45-52. 2005..1 microg MeHg/kg b.w. per day in 20% of the women. Thus, there seems to be no margin of safety for neurodevelopmental effects in fetus, for women with high fish consumption unless they decrease their intake of certain fish species... - Cadmium interacts with the transport of essential micronutrients in the mammary gland - a study in rural Bangladeshi womenMaria Kippler
Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
Toxicology 257:64-9. 2009..In conclusion, the present study may indicate that cadmium shares common transporters with iron and manganese for transfer to breast milk, but inhibits secretion of calcium to breast milk... - Burden of cadmium in early childhood: longitudinal assessment of urinary cadmium in rural BangladeshMaria Kippler
Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 17177 Stockholm, Sweden
Toxicol Lett 198:20-5. 2010..Urinary cadmium concentrations were particularly elevated at 3 months of age, indicating limited reabsorption and accumulation of cadmium in the kidneys, known to be the main site of cadmium burden in older children and adults... - Skin deposition of nickel, cobalt, and chromium in production of gas turbines and space propulsion componentsAnneli Julander
Institute of Environmental Medicine, Karolinska Institutet, SE 171 77 Stockholm, Sweden
Ann Occup Hyg 54:340-50. 2010..The skin exposure levels of nickel and cobalt detected are judged capable to induce sensitization and elicit allergic contact dermatitis... - Nickel deposited on the skin-visualization by DMG testAnneli Julander
Division of Occupational and Environmental Dermatology, Institute of Environmental Medicine, Karolinska Institutet, SE 171 77 Stockholm, Sweden
Contact Dermatitis 64:151-7. 2011..Visualization techniques may be powerful in showing exposures. The dimethylglyoxime (DMG) test might be used to establish skin exposure to nickel... - Arsenic methylation efficiency increases during the first trimester of pregnancy independent of folate statusRenee M Gardner
Institute of Environmental Medicine, Karolinska Institute, P O Box 210, 17177 Stockholm, Sweden
Reprod Toxicol 31:210-8. 2011.... - Evaluation of the three most commonly used analytical methods for determination of inorganic arsenic and its metabolites in urineAnna Lena Lindberg
Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Box 210, SE 171 77, Stockholm, Sweden
Toxicol Lett 168:310-8. 2007..Because of its considerably lower costs compared to HPLC-HG-ICPMS, it may be a good alternative in laboratories where the high cost of ICPMS is not justified in relation to the intended use of the instrument... - Developmental exposure to methylmercury alters learning and induces depression-like behavior in male miceNatalia Onishchenko
Division of Toxicology and Neurotoxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Toxicol Sci 97:428-37. 2007..This study provides novel evidence that the developmental exposure to MeHg can affect not only cognitive functions but also motivation-driven behaviors... - Tubular and glomerular kidney effects in Swedish women with low environmental cadmium exposureAgneta Akesson
Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
Environ Health Perspect 113:1627-31. 2005..Although the effects were small, they may represent early signs of adverse effects, affecting large segments of the population. Subjects with diabetes seem to be at increased risk... - Transport of methylmercury and inorganic mercury to the fetus and breast-fed infantKarolin Ask Björnberg
Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Environ Health Perspect 113:1381-5. 2005.... - Cadmium-induced bone effect is not mediated via low serum 1,25-dihydroxy vitamin DAnnette Engström
Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
Environ Res 109:188-92. 2009..Hence, decreased circulating levels of 1,25(OH)(2)D are unlikely to be the proposed link between cadmium-induced effects on kidney and bone... - Maternal and early life exposure to manganese in rural BangladeshKarin S Ljung
Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77, Stockholm, Sweden
Environ Sci Technol 43:2595-601. 2009..However, the implications of fetal exposurefrom elevated maternal exposure need further investigation... - Accumulation of cadmium in human placenta interacts with the transport of micronutrients to the fetusMaria Kippler
Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
Toxicol Lett 192:162-8. 2010..In conclusion, the Cd concentrations in placenta were clearly elevated, which seemed to impair Zn transfer to the fetus. Induction of MT explained the placental accumulation of Cd, but not the impairment of Zn transport... - Intra-individual variation in the metabolism of inorganic arsenicGabriela Concha
Institute of Environmental Medicine, Karolinska Institute, Box 210, 171 77 Stockholm, Sweden
Int Arch Occup Environ Health 75:576-80. 2002..No within-day variation in the percentage of MMA was observed. CONCLUSION: The arsenic methylation efficiency of an individual is remarkably stable over time... - Cadmium exposure in pregnancy and lactation in relation to iron statusAgneta Akesson
Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
Am J Public Health 92:284-7. 2002..The purpose of this study was to determine the impact of iron status on cadmium dose among pregnant women... - The effects of methylmercury on motor activity are sex- and age-dependent, and modulated by genetic deletion of adenosine receptors and caffeine administrationOlga Björklund
Department of Physiology and Pharmacology, Karolinska Institutet, S 171 77 Stockholm, Sweden
Toxicology 241:119-33. 2007..Thus, the consequences of MeHg toxicity during gestation and lactation can be reduced by adenosine A(1) and A(2A) receptor inactivation, either via their genetic deletion or by treatment with their antagonist caffeine... - Toxic metals and the menopauseMarie Vahter
Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE-171 77 Stockholm, Sweden
J Br Menopause Soc 10:60-4. 2004..There is a significant release of bone lead after the menopause, in association with the acceleration of bone resorption. Thus, postmenopausal women may be at increased risk of adverse effects of lead... - Benchmark dose for cadmium-induced osteoporosis in womenYasushi Suwazono
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Toxicol Lett 197:123-7. 2010..Our results provide additional scientific support for the low tolerably weekly intake (TWI) of cadmium set by the European Food Safety Authority in 2009... - Arsenic exposure in Hungary, Romania and SlovakiaAnna-Lena Lindberg
Institute of Environmental Medicine, Karolinska Institute, Box 210, SE-171 77 Stockholm, Sweden
J Environ Monit 8:203-8. 2006..Exposure to arsenic from food, mainly as DMA, and cigarette smoke, mainly as inorganic arsenic, are major determinants of arsenic exposure at very low concentrations of arsenic in drinking water... - Cadmium-induced effects on bone in a population-based study of womenAgneta Akesson
Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Environ Health Perspect 114:830-4. 2006..Key words: biochemical bone markers, bone mineral density, cadmium, lead, osteoporosis, women... - Time to re-evaluate the guideline value for manganese in drinking water?Karin Ljung
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Environ Health Perspect 115:1533-8. 2007..We reviewed the scientific background for the current health-based World Health Organization (WHO) guideline value for manganese in drinking water... - Benchmark dose for cadmium-induced renal effects in humansYasushi Suwazono
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Environ Health Perspect 114:1072-6. 2006..We suggest that the hybrid approach is more appropriate for estimation of the critical U-Cd concentration, because the choice of cutoff values in logistic models largely influenced the obtained critical U-Cd... - Implications of gender differences for human health risk assessment and toxicologyMarie Vahter
Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
Environ Res 104:70-84. 2007..Wherever possible and feasible, toxicologic and environmental epidemiological studies should be designed and have sufficient statistical power to quantify differential gender-based exposures and outcomes... - Release of nickel from coins and deposition onto skin from coin handling--comparing euro coins and SEKCarola Liden
Occupational and Environmental Dermatology, Department of Medicine in Solna, Karolinska Institutet, Stockholm, Sweden
Contact Dermatitis 59:31-7. 2008..Nickel exposure is the most common cause of contact allergy. The role of contact with nickel-containing coins has been controversial... - Impact of smoking and chewing tobacco on arsenic-induced skin lesionsAnna Lena Lindberg
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Environ Health Perspect 118:533-8. 2010..We recently reported that the main reason for the documented higher prevalence of arsenic-related skin lesions among men than among women is the result of less efficient arsenic metabolism... - Metabolism of low-dose inorganic arsenic in a central European population: influence of sex and genetic polymorphismsAnna Lena Lindberg
Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
Environ Health Perspect 115:1081-6. 2007..Arsenic is metabolized by reduction and methylation reactions, catalyzed by reductases and methyltransferases... - Highly active dimeric and low-activity tetrameric forms of selenium-containing rat thioredoxin reductase 1Olle Rengby
Division of Biochemistry, Medical Nobel Institute for Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 171 77 Stockholm, Sweden
Free Radic Biol Med 46:893-904. 2009..The tetrameric forms of the protein could represent hitherto unknown regulatory states of the enzyme...