Marie E Vahter

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. pmc Time to re-evaluate the guideline value for manganese in drinking water?
    Karin Ljung
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 115:1533-8. 2007
  2. pmc Nutritional status has marginal influence on the metabolism of inorganic arsenic in pregnant Bangladeshi women
    Li Li
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 116:315-21. 2008
  3. pmc Breast-feeding protects against arsenic exposure in Bangladeshi infants
    Britta Fängström
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 116:963-9. 2008
  4. pmc Impact of smoking and chewing tobacco on arsenic-induced skin lesions
    Anna Lena Lindberg
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 118:533-8. 2010
  5. pmc Elevated manganese concentrations in drinking water may be beneficial for fetal survival
    Syed Moshfiqur Rahman
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    PLoS ONE 8:e74119. 2013
  6. pmc Maternal cadmium exposure during pregnancy and size at birth: a prospective cohort study
    Maria Kippler
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 120:284-9. 2012
  7. pmc Spatial and temporal variations in arsenic exposure via drinking-water in northern Argentina
    Gabriela Concha
    Swedish National Food Administration, Toxicology Division, 75126, Uppsala, Sweden
    J Health Popul Nutr 24:317-26. 2006
  8. pmc Environmental exposure to metals and children's growth to age 5 years: a prospective cohort study
    Renee M Gardner
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Am J Epidemiol 177:1356-67. 2013
  9. pmc Pre- and postnatal arsenic exposure and body size to 2 years of age: a cohort study in rural Bangladesh
    Kuntal K Saha
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    Environ Health Perspect 120:1208-14. 2012
  10. pmc Metals and trace element concentrations in breast milk of first time healthy mothers: a biological monitoring study
    Karin Ljung Björklund
    Institute of Environmental Medicine, Karolinska Institutet, PO Box 210, 171 77, Stockholm, SE, Sweden
    Environ Health 11:92. 2012

Collaborators

Detail Information

Publications51

  1. pmc Time to re-evaluate the guideline value for manganese in drinking water?
    Karin Ljung
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 115:1533-8. 2007
    ..We reviewed the scientific background for the current health-based World Health Organization (WHO) guideline value for manganese in drinking water...
  2. pmc Nutritional status has marginal influence on the metabolism of inorganic arsenic in pregnant Bangladeshi women
    Li Li
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 116:315-21. 2008
    ..The interindividual variation in metabolism of inorganic arsenic (iAs), involving methylation via one-carbon metabolism, has been well documented, but the reasons remain unclear...
  3. pmc Breast-feeding protects against arsenic exposure in Bangladeshi infants
    Britta Fängström
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 116:963-9. 2008
    ..Arsenic readily crosses the placenta, but the few available data on postnatal exposure to arsenic via breast milk are not conclusive...
  4. pmc Impact of smoking and chewing tobacco on arsenic-induced skin lesions
    Anna Lena Lindberg
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 118:533-8. 2010
    ..We recently reported that the main reason for the documented higher prevalence of arsenic-related skin lesions among men than among women is the result of less efficient arsenic metabolism...
  5. pmc Elevated manganese concentrations in drinking water may be beneficial for fetal survival
    Syed Moshfiqur Rahman
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    PLoS ONE 8:e74119. 2013
    ..We assessed the effects of drinking water Mn exposure during pregnancy upon fetal and infant survival...
  6. pmc Maternal cadmium exposure during pregnancy and size at birth: a prospective cohort study
    Maria Kippler
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 120:284-9. 2012
    ..Cadmium (Cd) is an embryotoxic and teratogenic metal in a variety of animal species, but data from humans are limited...
  7. pmc Spatial and temporal variations in arsenic exposure via drinking-water in northern Argentina
    Gabriela Concha
    Swedish National Food Administration, Toxicology Division, 75126, Uppsala, Sweden
    J Health Popul Nutr 24:317-26. 2006
    ..Thus, arsenic concentration in urine seems to be a better marker of individual arsenic exposure than concentrations in drinking-water and hair...
  8. pmc Environmental exposure to metals and children's growth to age 5 years: a prospective cohort study
    Renee M Gardner
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Am J Epidemiol 177:1356-67. 2013
    ..67 kg, 95% CI: -0.82, -0.53) and height (-1.3 cm, 95% CI: -1.7, -0.89)...
  9. pmc Pre- and postnatal arsenic exposure and body size to 2 years of age: a cohort study in rural Bangladesh
    Kuntal K Saha
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    Environ Health Perspect 120:1208-14. 2012
    ..Exposure to arsenic via drinking water has been associated with adverse pregnancy outcomes and infant morbidity and mortality. Little is known, however, about the effects of arsenic on child growth...
  10. pmc Metals and trace element concentrations in breast milk of first time healthy mothers: a biological monitoring study
    Karin Ljung Björklund
    Institute of Environmental Medicine, Karolinska Institutet, PO Box 210, 171 77, Stockholm, SE, Sweden
    Environ Health 11:92. 2012
    ..There is no recent study on a large number of metals and trace elements in breast milk, using a sensitive analytical method for determination of low element concentrations...
  11. pmc Relation between dietary cadmium intake and biomarkers of cadmium exposure in premenopausal women accounting for body iron stores
    Bettina Julin
    Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health 10:105. 2011
    ..We aimed to assess the relationship between dietary cadmium intake assessed by analyses of duplicate food portions and cadmium concentrations in urine and blood, taking the toxicokinetics of cadmium into consideration...
  12. pmc Spatial patterns of fetal loss and infant death in an arsenic-affected area in Bangladesh
    Nazmul Sohel
    Department of Women s and Children s Health, International Maternal and Child Health, Uppsala University, Uppsala, Sweden
    Int J Health Geogr 9:53. 2010
    ....
  13. pmc Inter-individual variations of human mercury exposure biomarkers: a cross-sectional assessment
    Marika Berglund
    Department of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    Environ Health 4:20. 2005
    ..We have evaluated the most frequently used biomarkers and the physiology on which they are based, to explore the inter-individual variations and their suitability for exposure assessment...
  14. ncbi request reprint Interactions between arsenic-induced toxicity and nutrition in early life
    Marie E Vahter
    Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden
    J Nutr 137:2798-804. 2007
    ..A third mode of arsenic-nutrition interaction involves epigenetic effects and fetal programming via DNA methylation...
  15. ncbi request reprint Health effects of early life exposure to arsenic
    Marie Vahter
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Basic Clin Pharmacol Toxicol 102:204-11. 2008
    ....
  16. ncbi request reprint Influence of iron and zinc status on cadmium accumulation in Bangladeshi women
    Maria Kippler
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Toxicol Appl Pharmacol 222:221-6. 2007
    ..In conclusion, low iron stores were associated with increased cadmium accumulation, but only at adequate zinc status...
  17. ncbi request reprint Effects of arsenic on maternal and fetal health
    Marie Vahter
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Annu Rev Nutr 29:381-99. 2009
    ..Early-life exposure may induce changes that will become apparent much later in life...
  18. ncbi request reprint Arsenic exposure in pregnancy: a population-based study in Matlab, Bangladesh
    Marie E Vahter
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    J Health Popul Nutr 24:236-45. 2006
    ..There were marked geographical variations in exposure. The results emphasize the urgent need for efficient mitigation activities and investigations of arsenic-related reproductive effects...
  19. pmc Persistent exposure to arsenic via drinking water in rural Bangladesh despite major mitigation efforts
    Renee Gardner
    Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    Am J Public Health 101:S333-8. 2011
    ..We evaluated the effectiveness of long-term mitigation efforts by longitudinally measuring arsenic exposure in pregnant women and their children, the most susceptible population groups...
  20. pmc Inorganic mercury and methylmercury in placentas of Swedish women
    Karolin Ask
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 110:523-6. 2002
    ..We found no correlations between I-Hg and selenium. This study increases the understanding of Hg, in its different forms, in human placenta and how they are related to maternal and fetal exposure...
  21. ncbi request reprint Urinary arsenic concentration adjustment factors and malnutrition
    Barbro Nermell
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Res 106:212-8. 2008
    ..Furthermore, urinary creatinine was found to be significantly associated with urinary arsenic, which further disqualifies the creatinine adjustment...
  22. ncbi request reprint Maternal and early life exposure to manganese in rural Bangladesh
    Karin S Ljung
    Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77, Stockholm, Sweden
    Environ Sci Technol 43:2595-601. 2009
    ..However, the implications of fetal exposurefrom elevated maternal exposure need further investigation...
  23. ncbi request reprint The risk of arsenic induced skin lesions in Bangladeshi men and women is affected by arsenic metabolism and the age at first exposure
    Anna Lena Lindberg
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Toxicol Appl Pharmacol 230:9-16. 2008
    ..Thus, it can be speculated that this is due to a programming effect of arsenic in utero...
  24. ncbi request reprint Burden of cadmium in early childhood: longitudinal assessment of urinary cadmium in rural Bangladesh
    Maria Kippler
    Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 17177 Stockholm, Sweden
    Toxicol Lett 198:20-5. 2010
    ..Urinary cadmium concentrations were particularly elevated at 3 months of age, indicating limited reabsorption and accumulation of cadmium in the kidneys, known to be the main site of cadmium burden in older children and adults...
  25. ncbi request reprint Impaired arsenic metabolism in children during weaning
    Britta Fängström
    Institute of Environmental Medicine, Karolinska Institutet, Box 210, 17177 Stockholm, Sweden
    Toxicol Appl Pharmacol 239:208-14. 2009
    ..Methylation of inorganic arsenic (iAs) via one-carbon metabolism is a susceptibility factor for a range of arsenic-related health effects, but there is no data on the importance of arsenic metabolism for effects on child development...
  26. ncbi request reprint Skin deposition of nickel, cobalt, and chromium in production of gas turbines and space propulsion components
    Anneli Julander
    Institute of Environmental Medicine, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Ann Occup Hyg 54:340-50. 2010
    ..The skin exposure levels of nickel and cobalt detected are judged capable to induce sensitization and elicit allergic contact dermatitis...
  27. doi request reprint Cadmium interacts with the transport of essential micronutrients in the mammary gland - a study in rural Bangladeshi women
    Maria Kippler
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    Toxicology 257:64-9. 2009
    ..In conclusion, the present study may indicate that cadmium shares common transporters with iron and manganese for transfer to breast milk, but inhibits secretion of calcium to breast milk...
  28. ncbi request reprint Methyl mercury exposure in Swedish women with high fish consumption
    Karolin Ask Björnberg
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77, Stockholm, Sweden
    Sci Total Environ 341:45-52. 2005
    ..1 microg MeHg/kg b.w. per day in 20% of the women. Thus, there seems to be no margin of safety for neurodevelopmental effects in fetus, for women with high fish consumption unless they decrease their intake of certain fish species...
  29. ncbi request reprint Concentrations of biomarkers in spot urine samples need adjustment for variation in dilution--Comment on: "Distribution of urinary selenium and arsenic among pregnant women exposed to arsenic in drinking water" [Environ Res. 2006;100(1):115-122]
    Marie Vahter
    Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    Environ Res 104:312-3; discussion 314. 2007
  30. ncbi request reprint Gender and age differences in the metabolism of inorganic arsenic in a highly exposed population in Bangladesh
    Anna Lena Lindberg
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Res 106:110-20. 2008
    ..Overall, exposure level of arsenic, gender and age explained at most 30% of the variation in the present study, indicating that genetic polymorphisms are the most important factor influencing the metabolism of inorganic arsenic...
  31. ncbi request reprint Neurobehavioural and molecular changes induced by methylmercury exposure during development
    Carolina Johansson
    Division of Toxicology and Neurotoxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Neurotox Res 11:241-60. 2007
    ..This review summarises what is currently known about the neurodevelopmental effects of MeHg and consider the strength of different experimental approaches to study the effects of environmentally relevant exposure in vivo and in vitro...
  32. doi request reprint Arsenic methylation efficiency increases during the first trimester of pregnancy independent of folate status
    Renee M Gardner
    Institute of Environmental Medicine, Karolinska Institute, P O Box 210, 17177 Stockholm, Sweden
    Reprod Toxicol 31:210-8. 2011
    ....
  33. doi request reprint Nickel deposited on the skin-visualization by DMG test
    Anneli Julander
    Division of Occupational and Environmental Dermatology, Institute of Environmental Medicine, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Contact Dermatitis 64:151-7. 2011
    ..Visualization techniques may be powerful in showing exposures. The dimethylglyoxime (DMG) test might be used to establish skin exposure to nickel...
  34. pmc Transport of methylmercury and inorganic mercury to the fetus and breast-fed infant
    Karolin Ask Björnberg
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 113:1381-5. 2005
    ....
  35. pmc Tubular and glomerular kidney effects in Swedish women with low environmental cadmium exposure
    Agneta Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 113:1627-31. 2005
    ..Although the effects were small, they may represent early signs of adverse effects, affecting large segments of the population. Subjects with diabetes seem to be at increased risk...
  36. ncbi request reprint Evaluation of the three most commonly used analytical methods for determination of inorganic arsenic and its metabolites in urine
    Anna Lena Lindberg
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Box 210, SE 171 77, Stockholm, Sweden
    Toxicol Lett 168:310-8. 2007
    ..Because of its considerably lower costs compared to HPLC-HG-ICPMS, it may be a good alternative in laboratories where the high cost of ICPMS is not justified in relation to the intended use of the instrument...
  37. ncbi request reprint Developmental exposure to methylmercury alters learning and induces depression-like behavior in male mice
    Natalia Onishchenko
    Division of Toxicology and Neurotoxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Toxicol Sci 97:428-37. 2007
    ..This study provides novel evidence that the developmental exposure to MeHg can affect not only cognitive functions but also motivation-driven behaviors...
  38. doi request reprint Cadmium-induced bone effect is not mediated via low serum 1,25-dihydroxy vitamin D
    Annette Engström
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    Environ Res 109:188-92. 2009
    ..Hence, decreased circulating levels of 1,25(OH)(2)D are unlikely to be the proposed link between cadmium-induced effects on kidney and bone...
  39. doi request reprint Accumulation of cadmium in human placenta interacts with the transport of micronutrients to the fetus
    Maria Kippler
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Toxicol Lett 192:162-8. 2010
    ..In conclusion, the Cd concentrations in placenta were clearly elevated, which seemed to impair Zn transfer to the fetus. Induction of MT explained the placental accumulation of Cd, but not the impairment of Zn transport...
  40. pmc Cadmium exposure in pregnancy and lactation in relation to iron status
    Agneta Akesson
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Am J Public Health 92:284-7. 2002
    ..The purpose of this study was to determine the impact of iron status on cadmium dose among pregnant women...
  41. ncbi request reprint Intra-individual variation in the metabolism of inorganic arsenic
    Gabriela Concha
    Institute of Environmental Medicine, Karolinska Institute, Box 210, 171 77 Stockholm, Sweden
    Int Arch Occup Environ Health 75:576-80. 2002
    ..Therefore, we determined the variation in the relative amount of urinary arsenic metabolites, i.e., inorganic arsenic, MMA and DMA, over time in women living in an Andean village with elevated arsenic levels in drinking water...
  42. ncbi request reprint Toxic metals and the menopause
    Marie Vahter
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    J Br Menopause Soc 10:60-4. 2004
    ..There is a significant release of bone lead after the menopause, in association with the acceleration of bone resorption. Thus, postmenopausal women may be at increased risk of adverse effects of lead...
  43. ncbi request reprint The effects of methylmercury on motor activity are sex- and age-dependent, and modulated by genetic deletion of adenosine receptors and caffeine administration
    Olga Björklund
    Department of Physiology and Pharmacology, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Toxicology 241:119-33. 2007
    ..Thus, the consequences of MeHg toxicity during gestation and lactation can be reduced by adenosine A(1) and A(2A) receptor inactivation, either via their genetic deletion or by treatment with their antagonist caffeine...
  44. doi request reprint Release of nickel from coins and deposition onto skin from coin handling--comparing euro coins and SEK
    Carola Liden
    Occupational and Environmental Dermatology, Department of Medicine in Solna, Karolinska Institutet, Stockholm, Sweden
    Contact Dermatitis 59:31-7. 2008
    ..Nickel exposure is the most common cause of contact allergy. The role of contact with nickel-containing coins has been controversial...
  45. ncbi request reprint Arsenic exposure in Hungary, Romania and Slovakia
    Anna Lena Lindberg
    Institute of Environmental Medicine, Karolinska Institute, Box 210, SE 171 77 Stockholm, Sweden
    J Environ Monit 8:203-8. 2006
    ..Exposure to arsenic from food, mainly as DMA, and cigarette smoke, mainly as inorganic arsenic, are major determinants of arsenic exposure at very low concentrations of arsenic in drinking water...
  46. ncbi request reprint Implications of gender differences for human health risk assessment and toxicology
    Marie Vahter
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    Environ Res 104:70-84. 2007
    ..Wherever possible and feasible, toxicologic and environmental epidemiological studies should be designed and have sufficient statistical power to quantify differential gender-based exposures and outcomes...
  47. pmc Cadmium-induced effects on bone in a population-based study of women
    Agneta Akesson
    Division of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 114:830-4. 2006
    ..Key words: biochemical bone markers, bone mineral density, cadmium, lead, osteoporosis, women...
  48. doi request reprint Benchmark dose for cadmium-induced osteoporosis in women
    Yasushi Suwazono
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Toxicol Lett 197:123-7. 2010
    ..Our results provide additional scientific support for the low tolerably weekly intake (TWI) of cadmium set by the European Food Safety Authority in 2009...
  49. pmc Benchmark dose for cadmium-induced renal effects in humans
    Yasushi Suwazono
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Environ Health Perspect 114:1072-6. 2006
    ..Our goal in this study was to explore the use of a hybrid approach to calculate benchmark doses (BMDs) and their 95% lower confidence bounds (BMDLs) for renal effects of cadmium in a population with low environmental exposure...
  50. doi request reprint Highly active dimeric and low-activity tetrameric forms of selenium-containing rat thioredoxin reductase 1
    Olle Rengby
    Division of Biochemistry, Medical Nobel Institute for Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Free Radic Biol Med 46:893-904. 2009
    ..The tetrameric forms of the protein could represent hitherto unknown regulatory states of the enzyme...
  51. pmc Metabolism of low-dose inorganic arsenic in a central European population: influence of sex and genetic polymorphisms
    Anna Lena Lindberg
    Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    Environ Health Perspect 115:1081-6. 2007
    ..Arsenic is metabolized by reduction and methylation reactions, catalyzed by reductases and methyltransferases...