Research Topics
Species | Mikael TurunenSummaryAffiliation: Karolinska Institutet Country: Sweden Publications
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Detail Information
Publications
Metabolism and function of coenzyme QMikael Turunen
Department of Biochemistry and Biophysics, Stockholm University, Arrhenius Laboratories for Natural Sciences, SE 106 91 Stockholm, Sweden
Biochim Biophys Acta 1660:171-99. 2004..In this case the extent of disturbances is dependent on the localization and the modified distribution of the lipid at cellular and membrane levels...
Investigation of coenzyme Q biosynthesis in human fibroblast and HepG2 cellsMichael Tekle
Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden
J Biochem Biophys Methods 70:909-17. 2008..Thus, the biochemical characterization of the CoQ biosynthetic system in human cells is restricted to a few reliable analytical procedures...
On-line monitoring of apoptosis in insulin-secreting cellsMartin Kohler
Department of Molecular Medicine, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden
Diabetes 52:2943-50. 2003....
Defect in fatty acid esterification of dolichol in Niemann-Pick type C1 mouse livers in vivoMikael Turunen
Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden
Biochim Biophys Acta 1771:506-13. 2007..This proposal was strengthened by the finding that the amount of dolichol was decreased in an isolated Golgi fraction from npc1(-/-) mice...
Involvement of retinoid X receptor alpha in coenzyme Q metabolismMagnus Bentinger
Department of Biochemistry and Biophysics, Stockholm University, 10391 Stockholm, Sweden
J Mol Biol 326:795-803. 2003..The receptor is not involved in the elevated CoQ biosynthesis during peroxisomal induction...
4-Nitrobenzoate inhibits coenzyme Q biosynthesis in mammalian cell culturesUlrika Forsman
Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden
Nat Chem Biol 6:515-7. 2010..As 4-nitrobenzoate neither interfered with mitochondrial respiration nor induced oxidative stress, it should prove a valuable tool for studies on both Q deficiency and Q supplementation...
beta2-Integrin and lipid modifications indicate a non-antioxidant mechanism for the anti-atherogenic effect of dietary coenzyme Q10Mikael Turunen
Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden
Biochem Biophys Res Commun 296:255-60. 2002..Thus, these results strongly suggest that the anti-atherogenic effects of CoQ be mediated by other mechanisms beside its antioxidant protection...
