Mita M Thapar

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint In vitro recrudescence of Plasmodium falciparum parasites suppressed to dormant state by atovaquone alone and in combination with proguanil
    Mita M Thapar
    Department of Medicine, Infectious Diseases Unit, Malaria Research Laboratory, M9 02, Karolinska University Hospital, Karolinska Institute, SE 171 76 Stockholm, Sweden
    Trans R Soc Trop Med Hyg 99:62-70. 2005
  2. ncbi request reprint Pharmacodynamic interactions among atovaquone, proguanil and cycloguanil against Plasmodium falciparum in vitro
    Mita M Thapar
    Unit of Infectious Diseases, Department of Medicine, Karolinska Hospital, Stockholm, Sweden
    Trans R Soc Trop Med Hyg 97:331-7. 2003
  3. pmc Evidence of Plasmodium falciparum malaria resistant to atovaquone and proguanil hydrochloride: case reports
    Anna Farnert
    Department of Medicine, Division of Infectious Diseases, Karolinska Institute, Karolinska Hospital, S 171 76 Stockholm, Sweden
    BMJ 326:628-9. 2003
  4. ncbi request reprint Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (Malarone) when taken as chemoprophylaxis
    Mita M Thapar
    Department of Infectious Diseases, Malaria Research Laboratory, L7 03, Karolinska Hospital, Stockholm 17176, Sweden
    Eur J Clin Pharmacol 58:19-27. 2002

Detail Information

Publications4

  1. ncbi request reprint In vitro recrudescence of Plasmodium falciparum parasites suppressed to dormant state by atovaquone alone and in combination with proguanil
    Mita M Thapar
    Department of Medicine, Infectious Diseases Unit, Malaria Research Laboratory, M9 02, Karolinska University Hospital, Karolinska Institute, SE 171 76 Stockholm, Sweden
    Trans R Soc Trop Med Hyg 99:62-70. 2005
    ..The baseline susceptibilities of the parasites to individual drugs were similar before and after recrudescence in all experiments...
  2. ncbi request reprint Pharmacodynamic interactions among atovaquone, proguanil and cycloguanil against Plasmodium falciparum in vitro
    Mita M Thapar
    Unit of Infectious Diseases, Department of Medicine, Karolinska Hospital, Stockholm, Sweden
    Trans R Soc Trop Med Hyg 97:331-7. 2003
    ..We conclude that the effectiveness of Malarone is due to the synergism between atovaquone and proguanil and may not require the presence of cycloguanil...
  3. pmc Evidence of Plasmodium falciparum malaria resistant to atovaquone and proguanil hydrochloride: case reports
    Anna Farnert
    Department of Medicine, Division of Infectious Diseases, Karolinska Institute, Karolinska Hospital, S 171 76 Stockholm, Sweden
    BMJ 326:628-9. 2003
  4. ncbi request reprint Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (Malarone) when taken as chemoprophylaxis
    Mita M Thapar
    Department of Infectious Diseases, Malaria Research Laboratory, L7 03, Karolinska Hospital, Stockholm 17176, Sweden
    Eur J Clin Pharmacol 58:19-27. 2002
    ..To determine the pharmacokinetic profiles of atovaquone (ATO), proguanil (PROG) and its active metabolite cycloguanil (CYCLO) with respect to possible accumulation and kinetic interaction upon repeated dosing with Malarone...