Research Topics
| Leif SvenssonSummaryAffiliation: Karolinska Institutet Country: Sweden Publications
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Detail Information
Publications
Early identification and delay to treatment in myocardial infarction and stroke: differences and similaritiesJohan Herlitz
Institute of Medicine, Department of Molecular and Clinical Medicine, Sahlgrenska University Hospital, SE 413 45 Goteborg, Sweden
Scand J Trauma Resusc Emerg Med 18:48. 2010..This article aims to describe differences and similarities with regard to the way patients, bystanders and health care providers act in the acute phase of the two diseases with the emphasis on the pre-hospital phase...
[Mobile intensive care teams--a great deal remains to be proved]Leif Svensson
Lakartidningen 104:252-3; discussion 253-5. 2007
Comparison of very early treatment with either fibrinolysis or percutaneous coronary intervention facilitated with abciximab with respect to ST recovery and infarct-related artery epicardial flow in patients with acute ST-segment elevation myocardial infaLeif Svensson
Stockholm South Hospital, Stockholm, Sweden
Am Heart J 151:798.e1-7. 2006....
Compression-only CPR or standard CPR in out-of-hospital cardiac arrestLeif Svensson
Department of Clinical Science and Education, Karolinska Institutet at Södersjukhuset, Stockholm, Sweden
N Engl J Med 363:434-42. 2010..That study, however, was not powered to assess a possible difference in survival. The aim of this prospective, randomized study was to evaluate the possible superiority of compression-only CPR over standard CPR with respect to survival...
Out of hospital cardiac arrest outside home in Sweden, change in characteristics, outcome and availability for public access defibrillationMattias Ringh
Department of Cardiology, Karolinska Institutet, South Hospital, Stockholm, Sweden
Scand J Trauma Resusc Emerg Med 17:18. 2009..We describe the change in characteristics and outcome among these candidates in a 14 years perspective in Sweden...
Survival is similar after standard treatment and chest compression only in out-of-hospital bystander cardiopulmonary resuscitationKatarina Bohm
Department of Cardiology and Stockholm Prehospital Centre, Karolinska Institute, South General Hospital, Stockholm, Sweden
Circulation 116:2908-12. 2007....
Cost and health outcome of primary percutaneous coronary intervention versus thrombolysis in acute ST-segment elevation myocardial infarction-Results of the Swedish Early Decision reperfusion Study (SWEDES) trialMikael Aasa
Department of Clinical Science and Education, Karolinska Institutet, Sodersjukhuset, Stockholm, Sweden
Am Heart J 160:322-8. 2010..The aim of the study was to compare costs, clinical outcome, and quality-adjusted survival between primary PCI and thrombolysis...
Risk reduction for cardiac events after primary coronary intervention compared with thrombolysis for acute ST-elevation myocardial infarction (five-year results of the Swedish early decision reperfusion strategy [SWEDES] trial)Mikael Aasa
Karolinska Institutet, Sodersjukhuset, Stockholm, Sweden
Am J Cardiol 106:1685-91. 2010..Prehospital thrombolysis may, however, match PPCI in long-term outcome...
Temporal changes in TIMI myocardial perfusion grade in relation to epicardial flow, ST-resolution and left ventricular function after primary percutaneous coronary interventionMikael Aasa
South Stockholm General Hospital Karolinska Institute, Stockholm, Sweden
Coron Artery Dis 18:513-8. 2007..The aim of this analysis was to study the evolution of TMPG within the first week following primary percutaneous coronary intervention (PCI) and its association with ECG-derived ST-segment resolution (STRES) and recovery of LV function...
Implementation of prehospital thrombolysis in Sweden: components of delay until delivery of treatment and examination of treatment feasibilityLeif Svensson
Division of Cardiology, South Hospital, Stockholm, Sweden
Int J Cardiol 88:247-56. 2003..To evaluate the feasibility of prehospital thrombolysis in Sweden in terms of safety and to examine the various components of the delay between onset of symptoms and start of treatment...
Dispatcher-assisted telephone-guided cardiopulmonary resuscitation: an underused lifesaving systemKatarina Bohm
Department of Cardiology, Department of Clinical Science and Education Karolinska Institutet, Södersjukhuset bSOS Alarm, Swedish
Eur J Emerg Med 14:256-9. 2007....
Dual dispatch early defibrillation in out-of-hospital cardiac arrest: the SALSA-pilotJacob Hollenberg
Department of Cardiology, Karolinska Institute, South Hospital, SE 118 83 Stockholm, Sweden
Eur Heart J 30:1781-9. 2009..Out-of-hospital cardiac arrest (OHCA) is a major public health problem. The objective of this study is to explore the effects of a dual dispatch early defibrillation programme...
Improved survival after out-of-hospital cardiac arrest is associated with an increase in proportion of emergency crew--witnessed cases and bystander cardiopulmonary resuscitationJacob Hollenberg
Department of Cardiology, South Hospital, Karolinska Institute, SE 118 83 Stockholm, Sweden
Circulation 118:389-96. 2008..Out-of-hospital cardiac arrest (OHCA) is a major public health problem. We sought to describe changes in 1-month survival after OHCA in patients given cardiopulmonary resuscitation (CPR) during the last 14 years in Sweden...
Intra-arrest transnasal evaporative cooling: a randomized, prehospital, multicenter study (PRINCE: Pre-ROSC IntraNasal Cooling Effectiveness)Maaret Castren
Department of Clinical Science and Education, Karolinska Institutet, Stockholm, Sweden
Circulation 122:729-36. 2010..The aim of this study was to determine the safety, feasibility, and cooling efficacy of prehospital transnasal cooling in humans and to explore its effects on neurologically intact survival to hospital discharge...
Evaluation of medical command and control using performance indicators in a full-scale, major aircraft accident exerciseDan Gryth
Department of Clinical Science and Education, Söderjukhuset, Karolinska Institutet, Stockholm Prehospital Centre, Stockholm, Sweden
Prehosp Disaster Med 25:118-23. 2010..Command and control in disaster medicine organizations can benefit from objective results from disaster exercises to identify areas that must be improved...
Higher prehospital priority level of stroke improves thrombolysis frequency and time to stroke unit: the Hyper Acute STroke Alarm (HASTA) studyAnnika Berglund
Karolinska Institutet, Department of Clinical Science and Education, Sodersjukhuset, 118 83 Stockholm, Sweden
Stroke 43:2666-70. 2012....
Differentiating frailty in older people using the Swedish ambulance service: A retrospective auditVeronica Vicente
Karolinska Institutet, Department of Clinical Science and Education, Sodersjukhuset, Stockholm, Sweden Karolinska Institutet, Department of Stockholms Prehospital Centre, Sodersjukhuset, Stockholm, Sweden Electronic address
Int Emerg Nurs 20:228-35. 2012..Furthermore, the concept of frailty ought to be included in "The International Statistical Classification of Diseases and Related Health Problems" (ICD-10)...
Tricuspid annular velocity assessed by doppler tissue imaging as a marker of right ventricular involvement in the acute and late phase after a first ST elevation myocardial infarctionNils Witt
Department of Cardiology, Karolinska Institute at South Hospital Södersjukhuset, Stockholm, Sweden
Echocardiography 27:139-45. 2010..The aim of this study was to evaluate the use of tricuspid annular velocity assessed by Doppler tissue imaging (DTI) as a marker of RV involvement in patients with a first STEMI...
Parallel imaging: is GRAPPA a useful acquisition tool for MR imaging intended for volumetric brain analysis?Terri L Lindholm
Department of Diagnostic Medical Physics, Karolinska University Hospital Huddinge, Stockholm, Sweden
BMC Med Imaging 9:15. 2009..The principle question is, "Can parallel imaging be used to acquire images at 1.5 T of sufficient quality to allow volumetric analysis of patient brains?"..
Characteristics of cardiac arrest and resuscitation by age group: an analysis from the Swedish Cardiac Arrest RegistryJohan Herlitz
Department of Metabolism and Cardiovascular Research, Institute of Internal Medicine, Sahlgrenska University Hospital, SE 413 45 Goteborg, Sweden
Am J Emerg Med 25:1025-31. 2007..The objective of this study was to describe patients who experienced an out-of-hospital cardiac arrest (OHCA) by age group...
Characteristics and outcome among patients suffering out-of-hospital cardiac arrest due to drowningAndreas Claesson
Kungälv Ambulance Service, Kungälv, Sweden
Resuscitation 76:381-7. 2008..To describe the characteristics and outcome among patients with out-of-hospital cardiac arrest (OHCA) caused by drowning as compared with OHCA caused by a cardiac etiology (outside home)...
Is female sex associated with increased survival after out-of-hospital cardiac arrest?Johan Herlitz
Division of Cardiology, Sahlgrenska University Hospital, S 41345 Goteborg, Sweden
Resuscitation 60:197-203. 2004..To evaluate survival after out-of-hospital cardiac arrest in relation to sex...
Quality of out-of-hospital cardiopulmonary resuscitation with real time automated feedback: a prospective interventional studyJo Kramer-Johansen
Institute for Experimental Medical Research, University of Oslo, N 0407 Oslo, Norway
Resuscitation 71:283-92. 2006..To compare quality of CPR during out-of-hospital cardiac arrest with and without automated feedback...
Prehospital identification of acute coronary syndrome/myocardial infarction in relation to ST elevationLeif Svensson
Division of Cardiology, South Hospital, SE 118 83 Stockholm, Sweden
Int J Cardiol 98:237-44. 2005....
Efficacy of bystander CPR: intervention by lay people and by health care professionalsJohan Herlitz
Division of Cardiology, Sahlgrenska University Hospital, SE 413 45 Goteborg, Sweden
Resuscitation 66:291-5. 2005..The aim of this survey was to evaluate the impact on survival of no bystander CPR, lay bystander CPR and professional bystander CPR...
Factors associated with an increased chance of survival among patients suffering from an out-of-hospital cardiac arrest in a national perspective in SwedenJohan Herlitz
Division of Cardiology, Sahlgrenska University Hospital, Goteborg, Sweden
Am Heart J 149:61-6. 2005..To describe factors associated with an increased chance of survival among patients suffering from an out-of-hospital cardiac arrest in Sweden...
Quality of cardiopulmonary resuscitation during out-of-hospital cardiac arrestLars Wik
National Competence Center for Emergency Medicine, Ulleval University Hospital, Oslo, Norway
JAMA 293:299-304. 2005..Electrocardiographic analysis and defibrillation accounted for only small parts of intervals without chest compressions...
Changes in demographic factors and mortality after out-of-hospital cardiac arrest in SwedenJohan Herlitz
Division of Cardiology, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
Coron Artery Dis 16:51-7. 2005..To describe changes between 1992 and 2003 in age, sex, factors at resuscitation and survival among patients suffering from out-of-hospital cardiac arrest in Sweden...
Decrease in the occurrence of ventricular fibrillation as the initially observed arrhythmia after out-of-hospital cardiac arrest during 11 years in SwedenJohan Herlitz
Division of Cardiology, Sahlgrenska University Hospital, S 41345 Goteborg, Sweden
Resuscitation 60:283-90. 2004..To describe the change in the occurrence of ventricular fibrillation as initially observed arrhythmia among patients suffering from out-of-hospital cardiac arrest in Sweden...
A short delay from out of hospital cardiac arrest to call for ambulance increases survivalJohan Herlitz
Division of Cardiology, SU Sahlgrenska, Goteborg, Sweden
Eur Heart J 24:1750-5. 2003..To describe the relative impact on survival of the delay from estimated time of collapse to call for an ambulance among patients who suffer from a bystander witnessed out of hospital cardiac arrest of a cardiac aetiology...
Safety and delay time in prehospital thrombolysis of acute myocardial infarction in urban and rural areas in SwedenLeif Svensson
Division of Cardiology, South Hospital, SE 118 83 Stockholm, Sweden
Am J Emerg Med 21:263-70. 2003..Patients in urban areas had a higher ejection fraction and fewer symptoms of heart failure after 30 days and a lower 1-year mortality...
Prehospital diagnosis and start of treatment reduces time delay and mortality in real-life patients with STEMIErik Bjorklund
Department of Cardiology, University Hospital, Uppsala, Sweden
J Electrocardiol 38:186. 2005
[The Swedish Resuscitation Council's guidelines to increase survival after cardiac arrest]Johan Herlitz
Lakartidningen 104:588-90. 2007
Pre-hospital thrombolysis delivered by paramedics is associated with reduced time delay and mortality in ambulance-transported real-life patients with ST-elevation myocardial infarctionErik Bjorklund
Department of Cardiology, University Hospital of Uppsala, 751 85 Uppsala Sweden
Eur Heart J 27:1146-52. 2006..We therefore evaluated treatment delays and outcome in a large cohort of ambulance-transported real-life patients with ST-elevation myocardial infarction (STEMI) according to PHT delivered by paramedics or in-hospital thrombolysis...
Clinical consequences of the introduction of mechanical chest compression in the EMS system for treatment of out-of-hospital cardiac arrest-a pilot studyChrister Axelsson
Gothenburg EMS system, SE 402 24 Göteborg, Sweden
Resuscitation 71:47-55. 2006....
Predictors of myocardial damage prior to hospital admission among patients with acute chest pain or other symptoms raising a suspicion of acute coronary syndromeLeif Svensson
Division of Cardiology, South Hospital, SE 118 83 Stockholm, Sweden
Coron Artery Dis 14:225-31. 2003..To evaluate factors which, prior to hospital admission, predict the development of acute coronary syndrome or acute myocardial infarction among patients who call for an ambulance due to suspected acute coronary syndrome...
Chest-compression-only or full cardiopulmonary resuscitation?Leif Svensson
Lancet 369:1924-5; author reply 1925. 2007
Prehospital evaluation and treatment of a presumed acute coronary syndrome: what are the options?Johan Herlitz
Division of Cardiology, Sahlgrenska University Hospital, Goteborg, Sweden
Eur J Emerg Med 13:308-12. 2006..We need further studies, however, for most of these treatments including cost-benefit analysis, analysis of various logistic aspects and safety in order to confirm their value...
Health before and after adoption from Eastern EuropeMagnus Landgren
Department of Paediatrics, Skaraborg Hospital, Skovde, Sweden
Acta Paediatr 95:720-5. 2006..A population-based study of pre-adoption, arrival and post-adoption health...
Factors that influence the use of ambulance in acute coronary syndromeMarie Thuresson
Division of Cardiology, Orebro University Hospital, School of Health and Medical Sciences, Orebro, Sweden
Am Heart J 156:170-6. 2008..In spite of this, only 50% to 60% of persons with myocardial infarction initiate care by using the emergency medical service. The aim of this study was to define factors influencing the use of ambulance in ACS...
Thoughts, actions, and factors associated with prehospital delay in patients with acute coronary syndromeMarie Thuresson
Division of Cardiology, Orebro University Hospital, Orebro, Sweden
Heart Lung 36:398-409. 2007....
[Chest pain unit--viable option when risk of cardiac etiology is modest. Multitudinous patient population brought together for structured survey and care at appropriate level]Ake Ohlsson-Onerud
Kardiologiska kliniken, Sodersjukhuset, Stockholm
Lakartidningen 99:4848-53. 2002..During the first year 1424 patients were admitted and spent in median 24 hours at the unit. The main diagnosis at discharge were unspecified chest pain in 36% of the patients, ischemic heart disease (35%) and an other diagnosis (29%)...
[National quality registry for in-hospital cardiac arrest now started]Hohan Herlitz
Sahlgrenska Universitetssjukhuset,
Lakartidningen 104:3361-4. 2007
Early versus periprocedural administration of abciximab for primary angioplasty: a pooled analysis of 6 studiesJochen Gödicke
Eli Lilly and Company, Critical Care Europe, Geneva, Switzerland
Am Heart J 150:1015. 2005..We investigated the potential benefit of early use of abciximab by pooling data from all the available studies...
Symptoms and type of symptom onset in acute coronary syndrome in relation to ST elevation, sex, age, and a history of diabetesMarie Thuresson
Division of Cardiology, Orebro University Hospital, SE 701 85 Orebro, Sweden
Am Heart J 150:234-42. 2005..The aim of this study was therefore to explore the characteristics and severity of symptoms among patients with an ACS in overall terms and in relation to the type of ACS, sex, age, and diabetes...
