Irina Svechnikova

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi p21waf1/Cip1 partially mediates apoptosis in hepatocellular carcinoma cells
    Irina Svechnikova
    Department of Woman and Child Health, Pediatric Endocrinology Unit, Karolinska Institute and University Hospital, Q2 08, SE 171 76 Stockholm, Sweden
    Biochem Biophys Res Commun 354:466-71. 2007
  2. ncbi The influence of di-(2-ethylhexyl) phthalate on steroidogenesis by the ovarian granulosa cells of immature female rats
    I Svechnikova
    Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute and University Hospital, Q2 08, 171 76 Stockholm, Sweden
    J Endocrinol 194:603-9. 2007
  3. ncbi HDAC inhibitors effectively induce cell type-specific differentiation in human glioblastoma cell lines of different origin
    Irina Svechnikova
    Department of Woman and Child Health, Karolinska Institutet, Pediatric Endocrinology Unit, Q2 08, Karolinska University and Hospital, S 171 76 Stockholm, Sweden
    Int J Oncol 32:821-7. 2008
  4. ncbi Effects of resveratrol analogs on steroidogenesis and mitochondrial function in rat Leydig cells in vitro
    Konstantin Svechnikov
    Department of Woman and Child Health, Pediatric Endocrinology Unit, Q2 08, Karolinska Institute and University Hospital, SE 17176 Stockholm, Sweden
    J Appl Toxicol 29:673-80. 2009
  5. ncbi Inhibitory effects of mono-ethylhexyl phthalate on steroidogenesis in immature and adult rat Leydig cells in vitro
    Konstantin Svechnikov
    Department of Woman and Child Health, Pediatric Endocrinology Unit, Q2 08, Karolinska Institute and University Hospital, SE 17176 Stockholm, Sweden
    Reprod Toxicol 25:485-90. 2008
  6. ncbi Gender-Specific Adverse Effects of Mono-Ethylhexyl Phthalate on Steroidogenesis in Immature Granulosa Cells and Rat Leydig cell Progenitors in vitro
    Konstantin Svechnikova
    Department of Woman and Child Health, Pediatric Endocrinology Unit, Karolinska Institute and University Hospital Stockholm, Sweden
    Front Endocrinol (Lausanne) 2:9. 2011
  7. ncbi Apoptosis and tumor remission in liver tumor xenografts by 4-phenylbutyrate
    Irina Svechnikova
    Department of Clinical Neuroscience, Experimental Alcohol and Drug Addiction Research Section, Karolinska Hospital, CMM, L8:01, S-171 76 Stockholm, Sweden
    Int J Oncol 22:579-88. 2003

Collaborators

Detail Information

Publications7

  1. ncbi p21waf1/Cip1 partially mediates apoptosis in hepatocellular carcinoma cells
    Irina Svechnikova
    Department of Woman and Child Health, Pediatric Endocrinology Unit, Karolinska Institute and University Hospital, Q2 08, SE 171 76 Stockholm, Sweden
    Biochem Biophys Res Commun 354:466-71. 2007
    ..The results show that the p21 anti-sense construct prevents apoptosis, induced by HDAC inhibitors in Hep3B cells. The obtained results suggest an important role for p21 in mediating the apoptotic effect of HDACi...
  2. ncbi The influence of di-(2-ethylhexyl) phthalate on steroidogenesis by the ovarian granulosa cells of immature female rats
    I Svechnikova
    Pediatric Endocrinology Unit, Department of Woman and Child Health, Karolinska Institute and University Hospital, Q2 08, 171 76 Stockholm, Sweden
    J Endocrinol 194:603-9. 2007
    ..Together, these data indicate that DEHP exerts dual effects on the pituitary-gonadal axis, stimulating the hormonal function of the pituitary and, at the same time, by inhibiting steroidogenesis by GCs...
  3. ncbi HDAC inhibitors effectively induce cell type-specific differentiation in human glioblastoma cell lines of different origin
    Irina Svechnikova
    Department of Woman and Child Health, Karolinska Institutet, Pediatric Endocrinology Unit, Q2 08, Karolinska University and Hospital, S 171 76 Stockholm, Sweden
    Int J Oncol 32:821-7. 2008
    ..In summary, our results showed that these three glioblastoma cell lines display unique phenotypes and differentiation patterns in response to HDACi...
  4. ncbi Effects of resveratrol analogs on steroidogenesis and mitochondrial function in rat Leydig cells in vitro
    Konstantin Svechnikov
    Department of Woman and Child Health, Pediatric Endocrinology Unit, Q2 08, Karolinska Institute and University Hospital, SE 17176 Stockholm, Sweden
    J Appl Toxicol 29:673-80. 2009
    ....
  5. ncbi Inhibitory effects of mono-ethylhexyl phthalate on steroidogenesis in immature and adult rat Leydig cells in vitro
    Konstantin Svechnikov
    Department of Woman and Child Health, Pediatric Endocrinology Unit, Q2 08, Karolinska Institute and University Hospital, SE 17176 Stockholm, Sweden
    Reprod Toxicol 25:485-90. 2008
    ..This may partly explain the anti-androgenic effects of DEHP in vivo and indicate a higher susceptibility in younger subjects...
  6. ncbi Gender-Specific Adverse Effects of Mono-Ethylhexyl Phthalate on Steroidogenesis in Immature Granulosa Cells and Rat Leydig cell Progenitors in vitro
    Konstantin Svechnikova
    Department of Woman and Child Health, Pediatric Endocrinology Unit, Karolinska Institute and University Hospital Stockholm, Sweden
    Front Endocrinol (Lausanne) 2:9. 2011
    ..This may be involved in the development of pathological conditions including disorders of prenatal sex development that may attenuate future reproductive health...
  7. ncbi Apoptosis and tumor remission in liver tumor xenografts by 4-phenylbutyrate
    Irina Svechnikova
    Department of Clinical Neuroscience, Experimental Alcohol and Drug Addiction Research Section, Karolinska Hospital, CMM, L8:01, S-171 76 Stockholm, Sweden
    Int J Oncol 22:579-88. 2003
    ..Reduction in expression of alpha-fetoprotein was found both in Hep3B cells and xenografts, suggesting also a differentiation effect by PB...