Detail Information
Publications
Polyunsaturated eicosapentaenoic acid displaces proteins from membrane rafts by altering raft lipid compositionT M Stulnig
Department of Internal Medicine III, University of Vienna, A 1090 Vienna, Austria
J Biol Chem 276:37335-40. 2001..In conclusion, these data provide strong evidence that displacement of acylated proteins from rafts in PUFA-treated T cells is predominantly due to altered raft lipid composition...
Polyunsaturated fatty acids inhibit T cell signal transduction by modification of detergent-insoluble membrane domainsT M Stulnig
Department of Internal Medicine III, University of Vienna, A 1090 Vienna, Austria
J Cell Biol 143:637-44. 1998..In conclusion, PUFA enrichment selectively modifies the cytoplasmic layer of DRMs and this alteration could underlie the inhibition of T cell signal transduction by PUFAs...
Signal transduction via glycosyl phosphatidylinositol-anchored proteins in T cells is inhibited by lowering cellular cholesterolT M Stulnig
Department of Internal Medicine III, University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
J Biol Chem 272:19242-7. 1997..These results suggest that cellular cholesterol is an important prerequisite for signal transduction via GPI-anchored proteins beyond formation of membrane domains...
Elevated serum free fatty acid concentrations inhibit T lymphocyte signalingT M Stulnig
Department of Internal Medicine III, University of Vienna, Austria
FASEB J 14:939-47. 2000..In conclusion, our data emphasize that serum FFA elevation is able to exert immunosuppressive effects in vivo...
