G Steineck

..Acceptance of this model has implications for ascertaining the degree to which a study effectively evaluates the effects of cancer treatment (level of scientific evidence)...

..We evaluated symptoms and self-assessments of quality of life in men with localized prostate cancer who participated in a randomized comparison between radical prostatectomy and watchful waiting...

..We undertook a study to assess whether these substances are related to the risks of cancer in the large bowel and urinary tract...

..A time period describes symptom duration. The relevance of a symptom to emotions and social activities, sometimes cited as the associated symptom-induced distress, is a separate issue from symptom occurrence, intensity, and duration...

..The increased risk of "persistent' delayed nausea and vomiting seen in older patients with large tumour burden may have important clinical implications and warrants further attention...

..In the light of a report suggesting that insulin glargine may increase cancer occurrence, the EASD asked us to perform this study...

..We wanted to determine whether male spouses of cancer patients who died from their disease had received information that the illness was incurable and to determine their preferences of disclosure. Participants and..

..These data indicate that radical prostatectomy is associated with self-perceived penile shortening and suggests that erectile function is a key factor in penile shortening...

..We aimed to study care-related determinants of when parents gain awareness of their child's impending death to cancer, and whether the duration of this awareness affects the parents' long-term morbidity...

..We studied the relation between unrelieved symptoms in terminally ill children and the psychological well-being in the bereaved parents 4-9 years after their loss...

..The findings stress the nonepidemiological data concerning the potential carcinogenicity of acetaminophen and may be a foundation for future research of some other drugs and diseases...

..To investigate if a cancer patient's unrelieved symptoms during the last 3 months of life increase the risk of long-term psychological morbidity in the surviving widower...

..Loss of a child to malignancy is associated with long-term morbidity among surviving parents. This study aims to identify particular sources of stress among parents of children with severe malignancy...

..We suggest that bereaved parents of children undergoing HSCT may be at greater risk of decreased psychological well-being than other bereaved parents of children with cancer...

..We surveyed the occurrence of physical symptoms among long-term gynaecological cancer survivors after pelvic radiation therapy, and compared with population-based control women...

..A decline in sexual functions was the most common cause of disease-specific distress in men with prostate cancer...

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..7, 95% CI: 1.5, 21.4) at follow-up. These results show that to improve the long-term psychological well-being of widowers, it may be fruitful to identify care-related facilitators and inhibitors of preparedness...

..CONCLUSIONS: Well-being and subjective quality of life in patients after radical cystectomy and orthotopic bladder substitution were similar to those in a matched control population...

..To investigate to what extent prostate cancer patients confide their emotional concerns, and whether having no one to confide in affects well-being...

..However, most patients are in spite of this unwilling to compromise survival...

..At follow-up visits these issues can be attended to through information, with specific suggestions including advice about topical estrogen and dilators, to alleviate possible long-term sequelae...

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..1; 95% CI = 0.7-1.8; p for trend = 0.8). The results of this study are in line with the 2 previous studies examining dietary acrylamide and suggest there is no association between dietary acrylamide and risk of renal cell cancer...

..Diagnosis and treatment of cervical cancer may be improved by recognition of a sexual abuse history...

..We investigated parental risk of anxiety and depression 4-9 years after the loss of a child owing to a malignancy...

..To make a comprehensive, detailed inventory of gastrointestinal symptoms reported by gynaecological cancer survivors and control women from the general population...

..We conducted a population-based, nationwide study addressing this issue, focusing on potential care-related stressors in parents losing a child to cancer...

..Feelings of guilt are common after bereavement. We investigated whether feelings of guilt after the loss of a husband to cancer are associated with the health care provided at the time close to and at the moment of death...

..The authors investigated whether becoming a widow after the death of a husband from cancer results in long-term psychological or physical morbidity...

..We investigated the predictors and long-term consequences of awareness time - the length of time a woman is aware of her husband's impending death from cancer...

..The FHIT gene locus showed a relatively high frequency of LOH even in Ta tumours...

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..Among symptoms, long-term fecal leakage was the one fewest men were willing to accept to gain survival...

..In order to avoid a detrimental bias in a study on bereavement, psychological morbidity is probably best measured first in such a questionnaire...

..Parental feelings of guilt can be a serious problem after the death of a child to a malignancy. This study identified predictors of feelings of guilt in parents during the year after a child's death...

..Fecal incontinence is a symptom reported by cancer survivors after pelvic radiotherapy and is recognized to be one of the most troubling symptom-induced sources of distress to patients...

..4% who did not receive the information). Prevalence of children's unrelieved pain was 11.6% for those receiving home care and 15.3% for those receiving care outside the home...

..This error dilutes assessed associations with, for example, decreased quality of life. Nevertheless, the test-retest reliability for anal sphincter, large bowel and urinary symptoms indicates that surveys yield meaningful information...

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..We investigated the prevalence and predictors of access to bereavement interventions during the first 6 months after the loss of a husband/male partner to prostate or urinary bladder cancer...

..It is possible that patient care and clinical research can be made more effective by focusing on important sources of symptom-induced distress...

..CONCLUSIONS: The observed symptoms are distressful and should, if one focuses on patient satisfaction, be given priority...

..Understanding which symptoms affect children in the terminal phase of disease is crucial to improve palliative care...

..We conclude that the choice of three or four fields may imply a contrasting risk scenario for defecation urgency or diarrhoea in comparison with faecal leakage...

..Although the numerical data cannot be directly translated to ethical conclusions, they can provide guidance for future ethical decisions...

..Avoiding to induce long-term lymphedema or bladder-emptying difficulties would probably improve quality of life after radical hysterectomy (to cure cervical cancer). Few women want to compromise survival to avoid long-term symptoms...

..The rate ratio for men smoking a pipe/cigars, but not cigarettes, was 3.3 (95% confidence interval 1.5-7.4)...

..Our findings indicate that the C-->T and the T-->G changes occur simultaneously and belong to the same allelotype...

..If we can learn how to increase preparedness before the death of a loved one, we can possibly decrease the next-of-kin's long-term morbidity...

..Actions taken after a stillbirth can affect long-term psychological morbidity. Our objective was to study how infant bonding and maternal actions after stillbirth are associated with ensuing depressive symptoms...

..However, the high negative predictive value and the low positive predictive value suggest that the visual- digital scales mainly detect the absence of the symptoms...

..An orchidectomy may result in long-lasting feelings of loss and uneasiness or shame in some men; offering a testicular prosthesis may hinder this experience...

..In a European setting, we know little about the use of dietary supplements among men with prostate cancer (PCa) and to what extent lifestyle, disease or other factors influence such use...

..Vomiting was not consistently related to the excretion of either catecholamine. The results indicate that noradrenaline modulates delayed nausea resulting from chemotherapy...

..Antibodies to interferon developed frequently in patients receiving high dose oligomeric interferon therapy but rarely in patients receiving low dose monomeric interferon treatment...

..In epidemiological studies researchers use logistic regression as an analytical tool to study the association of a binary outcome to a set of possible exposures...

..Radical prostatectomy is associated with specific complications that can affect outcome results in patients...

..The prevalence of sexual dysfunction was lower than after cystectomy and the prevalence of distress from the gastrointestinal tract was comparable...

..Therefore, we investigated nocturnal urinary disturbances and quality of life in individuals who have undergone cystectomy with urinary diversion for bladder cancer...

..This study aims to determine the predictors for the symptomatic prostate cancer patient's delays in seeking care...

..To evaluate risk factors - notably drugs - for developing acute pancreatitis...

..In the present series, TaG1 tumours behaved benignly. The disease-specific mortality rate was low for initial TaG2 tumours, intermediate for initial TaG3 and T1 tumours and high for initial T2+ tumours...

..Future studies should pay more attention to the anal-sphincter region and help to more rigorously define its radiotherapeutic tolerance...

..Data directly addressing the long-term fracture risk in men diagnosed with prostate cancer are limited...

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..To define the characteristics of prostate cancer patients who use the Internet...

..To study how social support is associated with ensuing maternal depression following stillbirth...

..Variability in interviewers' ability to ascertain information is a possible source of bias in interview-based case-control studies when "blinding" cannot be achieved...

..Given the dearth of epidemiological data regarding these cancers and the lack of established biological mechanisms, confirmatory data are needed...

..Also, the validity of the relative seriality model for this clinical case needs to be examined by associating the clinical follow-up results with the predicted complication rates...

..However, delayed nausea and vomiting is still a major problem and the underlying mechanism is obscure...

..The A683C polymorphism did not cosegregate with other TNFRSF10A polymorphisms previously described. Thus screening for 683A-->C nucleotide exchanges may become important in diagnosis and/or treatment of these malignancies...

..61, CI 0.82-26.04). No significant associations were found for the NAT2 gene. Our results suggest that impaired glutathione conjugation may affect the mutation spectrum in critical target genes...

..To evaluate risk factors, notably drugs, for acute pancreatitis...

..Further, the results indicate, a role for the 3' UTR polymorphisms in the CDKN2A gene in tumor invasiveness...

..The results support the use of cytotoxic drugs in the relapsed setting and definitive trials are ongoing to prove any benefit to survival...

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..To evaluate the effect of lower urinary tract symptoms (LUTS) on self-assessed health, sadness and happiness of men...