Research Topics
| Jonas SpaakSummaryAffiliation: Karolinska Institutet Country: Sweden Publications
| Collaborators
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Detail Information
Publications
Dose-related effects of red wine and alcohol on hemodynamics, sympathetic nerve activity, and arterial diameterJonas Spaak
University Health Network, Mount Sinai Hospital, Division of Cardiology, Department of Medicine, University of Toronto, Ontario, Canada
Am J Physiol Heart Circ Physiol 294:H605-12. 2008..These acute effects, which exhibit a narrow dose response, are not modified by red wine polyphenols...
Dose-related effects of red wine and alcohol on heart rate variabilityJonas Spaak
University Health Network and Mount Sinai Hospital Division of Cardiology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Am J Physiol Heart Circ Physiol 298:H2226-31. 2010..When compared with respective baselines, two alcoholic drinks increased HR by diminished vagal and augmented sympathetic HR modulation. Thus alcohol exerts dose-dependent HRV responses, with RW and EtOH having a similar effect...
Muscle sympathetic nerve activity during wakefulness in heart failure patients with and without sleep apneaJonas Spaak
University Health Network, Mount Sinai Hospital, Division of Cardiology, Department of Medicine, University of Toronto, Ontario, Canada
Hypertension 46:1327-32. 2005..This additional stimulus to central sympathetic outflow may accelerate the progression of HF; its attenuation by treatment of sleep apnea represents a novel nonpharmacological opportunity...
Comparison of muscle sympathetic activity in ischemic and nonischemic heart failureCatherine F Notarius
Toronto General Research Institute, Toronto, Ontario, Canada
J Card Fail 13:470-5. 2007....
Inhibition of awake sympathetic nerve activity of heart failure patients with obstructive sleep apnea by nocturnal continuous positive airway pressureKengo Usui
University Health Network, University of Toronto, 600 University Avenue, Toronto, Ontario M5G 1XS, Canada
J Am Coll Cardiol 45:2008-11. 2005..Inhibition of increased central sympathetic vasoconstrictor outflow is one mechanism by which nocturnal CPAP reduces awake BP in HF patients with moderate to severe OSA...
Long-term bed rest-induced reductions in stroke volume during rest and exercise: cardiac dysfunction vs. volume depletionJonas Spaak
Sect of Environmental Physiology, Dept of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
J Appl Physiol 98:648-54. 2005..However, the ability to maintain blood pressure and to perform sustained low levels of dynamic exercise is not influenced by HDT...
