Ilona Silins

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. doi request reprint Data and literature gathering in chemical cancer risk assessment
    Ilona Silins
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Integr Environ Assess Manag 8:412-7. 2012
  2. pmc A comparison and user-based evaluation of models of textual information structure in the context of cancer risk assessment
    Yufan Guo
    Computer Laboratory, University of Cambridge, 15 JJ Thomson Avenue, Cambridge CB30FD, UK
    BMC Bioinformatics 12:69. 2011
  3. pmc The first step in the development of Text Mining technology for Cancer Risk Assessment: identifying and organizing scientific evidence in risk assessment literature
    Anna Korhonen
    Computer Laboratory, University of Cambridge, Cambridge, UK
    BMC Bioinformatics 10:303. 2009
  4. pmc Combined toxic exposures and human health: biomarkers of exposure and effect
    Ilona Silins
    Institute of Environmental Medicine, Karolinska Institutet, Box 210, 171 77 Stockholm, Sweden
    Int J Environ Res Public Health 8:629-47. 2011
  5. ncbi request reprint Induction of preneoplastic rat liver lesions with an attenuated p53 response by low doses of diethylnitrosamine
    Ilona Silins
    Institute of Environmental Medicine, Karolinska Institutet, Box 210, S 171 77 Stockholm, Sweden
    Arch Toxicol 78:540-8. 2004
  6. ncbi request reprint Dietary sphingolipids suppress a subset of preneoplastic rat liver lesions exhibiting high PTEN, low phospho-Akt and high levels of ceramide species
    Ilona Silins
    Occupational Toxicology Group, Institute of Environmental Medicine, Karolinska Institutet, Box 210, S 171 77 Stockholm, Sweden
    Food Chem Toxicol 44:1552-61. 2006
  7. doi request reprint Gender differences in chemical carcinogenesis in National Toxicology Program 2-year bioassays
    Sandeep Kadekar
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Toxicol Pathol 40:1160-8. 2012
  8. pmc Exocrine pancreatic carcinogenesis and autotaxin expression
    Sandeep Kadekar
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 7:e43209. 2012
  9. ncbi request reprint Chemical induced alterations in p53 signaling
    Johan Hogberg
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    EXS 99:181-208. 2009
  10. doi request reprint Active learning-based information structure analysis of full scientific articles and two applications for biomedical literature review
    Yufan Guo
    Computer Laboratory, University of Cambridge, Cambridge, UK
    Bioinformatics 29:1440-7. 2013

Collaborators

Detail Information

Publications12

  1. doi request reprint Data and literature gathering in chemical cancer risk assessment
    Ilona Silins
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Integr Environ Assess Manag 8:412-7. 2012
    ..However, our proposal offers a starting point for improved data and literature gathering that can benefit the whole cancer risk assessment process...
  2. pmc A comparison and user-based evaluation of models of textual information structure in the context of cancer risk assessment
    Yufan Guo
    Computer Laboratory, University of Cambridge, 15 JJ Thomson Avenue, Cambridge CB30FD, UK
    BMC Bioinformatics 12:69. 2011
    ..Some schemes of textual information structure have proved useful for biomedical text mining (BIO-TM) tasks (e.g. automatic summarization). However, user-centered evaluation in the context of real-life tasks has been lacking...
  3. pmc The first step in the development of Text Mining technology for Cancer Risk Assessment: identifying and organizing scientific evidence in risk assessment literature
    Anna Korhonen
    Computer Laboratory, University of Cambridge, Cambridge, UK
    BMC Bioinformatics 10:303. 2009
    ....
  4. pmc Combined toxic exposures and human health: biomarkers of exposure and effect
    Ilona Silins
    Institute of Environmental Medicine, Karolinska Institutet, Box 210, 171 77 Stockholm, Sweden
    Int J Environ Res Public Health 8:629-47. 2011
    ..Solid evidence shows that these groups of chemicals can interact and even produce synergistic effects. They may act during sensitive time windows and biomonitoring their effects in epidemiological studies is a challenging task...
  5. ncbi request reprint Induction of preneoplastic rat liver lesions with an attenuated p53 response by low doses of diethylnitrosamine
    Ilona Silins
    Institute of Environmental Medicine, Karolinska Institutet, Box 210, S 171 77 Stockholm, Sweden
    Arch Toxicol 78:540-8. 2004
    ..Instead, it is suggested that time is an important determinant for its development at low doses and that a delayed type of apoptosis might be important...
  6. ncbi request reprint Dietary sphingolipids suppress a subset of preneoplastic rat liver lesions exhibiting high PTEN, low phospho-Akt and high levels of ceramide species
    Ilona Silins
    Occupational Toxicology Group, Institute of Environmental Medicine, Karolinska Institutet, Box 210, S 171 77 Stockholm, Sweden
    Food Chem Toxicol 44:1552-61. 2006
    ....
  7. doi request reprint Gender differences in chemical carcinogenesis in National Toxicology Program 2-year bioassays
    Sandeep Kadekar
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Toxicol Pathol 40:1160-8. 2012
    ..In conclusion, gender-specific tumors were common. The male dominance is in line with recent human data, and the male susceptibility to carcinogens should be further studied...
  8. pmc Exocrine pancreatic carcinogenesis and autotaxin expression
    Sandeep Kadekar
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 7:e43209. 2012
    ..ATX may interact with hormones or onco- or suppressor-genes often deregulated in exocrine pancreatic cancer. Our data suggest that ATX is a target for chemicals promoting pancreatic tumor development...
  9. ncbi request reprint Chemical induced alterations in p53 signaling
    Johan Hogberg
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    EXS 99:181-208. 2009
    ..In the final section of this chapter we discuss future aspects on how knowledge about p53 can be used in testing of carcinogens and in risk assessment...
  10. doi request reprint Active learning-based information structure analysis of full scientific articles and two applications for biomedical literature review
    Yufan Guo
    Computer Laboratory, University of Cambridge, Cambridge, UK
    Bioinformatics 29:1440-7. 2013
    ..Additionally, we introduce two novel applications that use AZ to support real-life literature review in biomedicine via question answering and summarization...
  11. ncbi request reprint Characterizing the role of MDM2 in diethylnitrosamine induced acute liver damage and development of pre-neoplastic lesions
    Niklas Finnberg
    Occupational Toxicology Group, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE 171 77 Stockholm, Sweden
    Carcinogenesis 25:113-22. 2004
    ..The data support the hypothesis that EAF hepatocytes are initiated via epigenetic mechanisms...
  12. doi request reprint Weakly supervised learning of information structure of scientific abstracts--is it accurate enough to benefit real-world tasks in biomedicine?
    Yufan Guo
    Computer Laboratory, University of Cambridge, Cambridge CB3 0FD, UK
    Bioinformatics 27:3179-85. 2011
    ..These results suggest that weakly supervised learning could be used to improve the practical usefulness of information structure for real-life tasks in biomedicine...