E Severinson

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Regulation of adhesion and motility in B lymphocytes
    E Severinson
    Department of Cell and Molecular Biology, Karolinska Institutet, Box 285, SE 171 77 Stockholm, Sweden
    Scand J Immunol 58:139-44. 2003
  2. ncbi request reprint HS1,2 enhancer regulation of germline epsilon and gamma2b promoters in murine B lymphocytes: evidence for specific promoter-enhancer interactions
    J Laurencikiene
    Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
    J Immunol 167:3257-65. 2001
  3. ncbi request reprint Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes
    L Westerberg
    Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
    Blood 98:1086-94. 2001
  4. ncbi request reprint CD2: a functional adhesion molecule on murine B cells, involved in interleukin-4-induced aggregation
    C Elenström-Magnusson
    Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden
    Eur J Immunol 23:888-92. 1993
  5. ncbi request reprint STAT6 is required for the regulation of IL-4-induced cytoskeletal events in B cells
    E J Davey
    Department of Cell and Molecular Biology, Box 285, Karolinska Institutet, 171 77 Stockholm, Sweden
    Int Immunol 12:995-1003. 2000
  6. ncbi request reprint Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site
    M Lundgren
    Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden
    J Immunol 153:2983-95. 1994
  7. ncbi request reprint Differential activation of signal transducer and activator of transcription 6 in B cells from allergic children and their non-allergic siblings
    V Deveikaite
    Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
    Clin Exp Allergy 34:576-82. 2004
  8. ncbi request reprint IgG1 induction factor: a single molecular entity with multiple biological functions
    P Sideras
    Adv Exp Med Biol 213:227-36. 1987
  9. ncbi request reprint Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II
    T Kinashi
    Nature 324:70-3. 1986
  10. ncbi request reprint Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter
    Y Noma
    Nature 319:640-6. 1986

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Regulation of adhesion and motility in B lymphocytes
    E Severinson
    Department of Cell and Molecular Biology, Karolinska Institutet, Box 285, SE 171 77 Stockholm, Sweden
    Scand J Immunol 58:139-44. 2003
    ..In this review, we summarize our own research in this area. We give evidence for involvement of different adhesion and signalling molecules, and by the end, we speculate on the in vivo significance of our findings...
  2. ncbi request reprint HS1,2 enhancer regulation of germline epsilon and gamma2b promoters in murine B lymphocytes: evidence for specific promoter-enhancer interactions
    J Laurencikiene
    Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
    J Immunol 167:3257-65. 2001
    ..Our findings indicate that different sites in HS1,2 might selectively interact with the GL epsilon and gamma2b promoters. We also provide evidence that B cell-specific activator protein is not an absolute suppressor of HS1,2 activity...
  3. ncbi request reprint Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes
    L Westerberg
    Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
    Blood 98:1086-94. 2001
    ..Aberrations in WASP-deficient B lymphocytes, described here, provide further evidence that WAS is a cytoskeletal disease of hematopoietic cells. (Blood. 2001;98:1086-1094)..
  4. ncbi request reprint CD2: a functional adhesion molecule on murine B cells, involved in interleukin-4-induced aggregation
    C Elenström-Magnusson
    Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden
    Eur J Immunol 23:888-92. 1993
    ..We also report that interleukin 4-induced B cell homotypic adhesion involves CD2-mediated cell binding, since the antibodies specific for mouse, CD2, inhibited interleukin-4-induced cell aggregation...
  5. ncbi request reprint STAT6 is required for the regulation of IL-4-induced cytoskeletal events in B cells
    E J Davey
    Department of Cell and Molecular Biology, Box 285, Karolinska Institutet, 171 77 Stockholm, Sweden
    Int Immunol 12:995-1003. 2000
    ..A possible interpretation of our results is that STAT6-dependent expression of a specific gene or genes is required for IL-4 to affect changes in B cell morphology...
  6. ncbi request reprint Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site
    M Lundgren
    Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden
    J Immunol 153:2983-95. 1994
    ..The -125/-101 segment previously has been shown to be required for transcriptional activation. We discuss these findings in relation to the presence of consensus C/EBP binding sites in other IL-4-regulated promoters...
  7. ncbi request reprint Differential activation of signal transducer and activator of transcription 6 in B cells from allergic children and their non-allergic siblings
    V Deveikaite
    Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
    Clin Exp Allergy 34:576-82. 2004
    ..IL-4-induced gene expression is largely mediated through activation of latent transcription factor STAT6 (signal transducer and activator of transcription 6)...
  8. ncbi request reprint IgG1 induction factor: a single molecular entity with multiple biological functions
    P Sideras
    Adv Exp Med Biol 213:227-36. 1987
    ....
  9. ncbi request reprint Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II
    T Kinashi
    Nature 324:70-3. 1986
    ..To elucidate the molecular properties of TRF we isolated cDNA encoding TRF from the 2.19 T-cell line and report here the structure and multiple activities of this lymphokine...
  10. ncbi request reprint Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter
    Y Noma
    Nature 319:640-6. 1986
    ..The lymphokine synthesized by the direction of this cloned cDNA has many other functions, such as production of B-cell growth factor-1 and induction of Ia on B cells...