Ivanka Savic

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. pmc Long-term occupational stress is associated with regional reductions in brain tissue volumes
    Eva Blix
    Stockholm Brain Institute, Department of Women s and Children s Health, Division of Pediatric Neurology, Karolinska Institute, Stockholm, Sweden
    PLoS ONE 8:e64065. 2013
  2. doi Advances in research on the neurological and neuropsychiatric phenotype of Klinefelter syndrome
    Ivanka Savic
    Department of Clinical Neuroscience, Karolinska Institute, Solna, Stockholm, Sweden
    Curr Opin Neurol 25:138-43. 2012
  3. doi Sex dimorphism of the brain in male-to-female transsexuals
    Ivanka Savic
    Stockholm Brain Institute, Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    Cereb Cortex 21:2525-33. 2011
  4. pmc Androstenol--a steroid derived odor activates the hypothalamus in women
    Ivanka Savic
    Stockholm Brain Institute, Karolinska Institutet, Department of Clinical Neuroscience, Stockholm, Sweden
    PLoS ONE 5:e8651. 2010
  5. doi Pheromone signal transduction in humans: what can be learned from olfactory loss
    Ivanka Savic
    Stockholm Brain Institute, Department of Clinical Neuroscience, Karolinska University Hospital, MR Centre, Sweden
    Hum Brain Mapp 30:3057-65. 2009
  6. pmc PET and MRI show differences in cerebral asymmetry and functional connectivity between homo- and heterosexual subjects
    Ivanka Savic
    Stockholm Brain Institute, Department of Clinical Neuroscience, Karolinska Institute, 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 105:9403-8. 2008
  7. ncbi Imaging of odor perception delineates functional disintegration of the limbic circuits in mesial temporal lobe epilepsy
    Carolina Ciumas
    Department of Clinical Neuroscience, Division of Neurology, Karolinska University Hospital, Karolinska Institutet, Sweden
    Neuroimage 39:578-92. 2008
  8. ncbi Passive perception of odors and semantic circuits
    Ivanka Savic
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Hum Brain Mapp 21:271-8. 2004
  9. pmc Brain response to putative pheromones in lesbian women
    Hans Berglund
    Department of Medicine, and Stockholm Brain Institute, Karolinska University Hospital, Karolinska Institutet, 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 103:8269-74. 2006
  10. pmc Women with multiple chemical sensitivity have increased harm avoidance and reduced 5-HT(1A) receptor binding potential in the anterior cingulate and amygdala
    Lena Hillert
    Department of Public Health Sciences, Division of Occupational and Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e54781. 2013

Collaborators

Detail Information

Publications24

  1. pmc Long-term occupational stress is associated with regional reductions in brain tissue volumes
    Eva Blix
    Stockholm Brain Institute, Department of Women s and Children s Health, Division of Pediatric Neurology, Karolinska Institute, Stockholm, Sweden
    PLoS ONE 8:e64065. 2013
    ..The present findings of morphological changes in these regions confirm our previous conclusion that symptoms from occupational stress merit careful investigations and targeted treatment...
  2. doi Advances in research on the neurological and neuropsychiatric phenotype of Klinefelter syndrome
    Ivanka Savic
    Department of Clinical Neuroscience, Karolinska Institute, Solna, Stockholm, Sweden
    Curr Opin Neurol 25:138-43. 2012
    ..The aim of this review is to combine available brain imaging and behavioral data to provide an overview of what we have learned about the neural underpinnings of cognitive, emotional and behavioral dysunctions in Klinefelter syndrome...
  3. doi Sex dimorphism of the brain in male-to-female transsexuals
    Ivanka Savic
    Stockholm Brain Institute, Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    Cereb Cortex 21:2525-33. 2011
    ..The present data do not support the notion that brains of MtF-TR are feminized. The observed changes in MtF-TR bring attention to the networks inferred in processing of body perception...
  4. pmc Androstenol--a steroid derived odor activates the hypothalamus in women
    Ivanka Savic
    Stockholm Brain Institute, Karolinska Institutet, Department of Clinical Neuroscience, Stockholm, Sweden
    PLoS ONE 5:e8651. 2010
    ..A further issue was to evaluate whether the pattern of activation resembles the pattern of common odors...
  5. doi Pheromone signal transduction in humans: what can be learned from olfactory loss
    Ivanka Savic
    Stockholm Brain Institute, Department of Clinical Neuroscience, Karolinska University Hospital, MR Centre, Sweden
    Hum Brain Mapp 30:3057-65. 2009
    ..The anosmics inability to activate the hypothalamus with EST, therefore, suggests that in healthy men EST signals were primarily transmitted via the olfactory system...
  6. pmc PET and MRI show differences in cerebral asymmetry and functional connectivity between homo- and heterosexual subjects
    Ivanka Savic
    Stockholm Brain Institute, Department of Clinical Neuroscience, Karolinska Institute, 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 105:9403-8. 2008
    ..The present study shows sex-atypical cerebral asymmetry and functional connections in homosexual subjects. The results cannot be primarily ascribed to learned effects, and they suggest a linkage to neurobiological entities...
  7. ncbi Imaging of odor perception delineates functional disintegration of the limbic circuits in mesial temporal lobe epilepsy
    Carolina Ciumas
    Department of Clinical Neuroscience, Division of Neurology, Karolinska University Hospital, Karolinska Institutet, Sweden
    Neuroimage 39:578-92. 2008
    ..It shows an altered response in several regions, which may underlie some interictal behavioral problems associated with this condition...
  8. ncbi Passive perception of odors and semantic circuits
    Ivanka Savic
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Hum Brain Mapp 21:271-8. 2004
    ..Already the most elemental form of odor processing, passive perception thus seems to engage semantic circuits. This is achieved by the ability of odorants to immediately elicit associations and judgments of odor characteristics...
  9. pmc Brain response to putative pheromones in lesbian women
    Hans Berglund
    Department of Medicine, and Stockholm Brain Institute, Karolinska University Hospital, Karolinska Institutet, 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 103:8269-74. 2006
    ..These data support our previous results about differentiated processing of pheromone-like stimuli in humans and further strengthen the notion of a coupling between hypothalamic neuronal circuits and sexual preferences...
  10. pmc Women with multiple chemical sensitivity have increased harm avoidance and reduced 5-HT(1A) receptor binding potential in the anterior cingulate and amygdala
    Lena Hillert
    Department of Public Health Sciences, Division of Occupational and Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e54781. 2013
    ....
  11. ncbi Odor processing in multiple chemical sensitivity
    Lena Hillert
    Department of Public Health Sciences, Division of Occupational Medicine, Karolinska Institutet, Stockholm, Sweden
    Hum Brain Mapp 28:172-82. 2007
    ..One possible explanation for the observed pattern of activation in MCS is a top-down regulation of odor-response via cingulate cortex...
  12. ncbi Brain imaging studies of the functional organization of human olfaction
    Ivanka Savic
    Department of Neuroscience, Division of Human Brain Mapping, Karolinska Institute, Stockholm, Sweden
    Chem Senses 30:i222-3. 2005
  13. ncbi Imaging of brain activation by odorants in humans
    Ivanka Savic
    Department of Neuroscience, Karolinska Institute, Retziusvag 8, 17177, Stockholm, Sweden
    Curr Opin Neurobiol 12:455-61. 2002
    ....
  14. doi The dopamine system in idiopathic generalized epilepsies: identification of syndrome-related changes
    Carolina Ciumas
    Stockholm Brain Institute, and Department of Clinical Neuroscience, Karolinska Institutet, Sweden
    Neuroimage 51:606-15. 2010
    ..The present data suggest that the two forms of IGE have different neuronal substrates...
  15. pmc Brain response to putative pheromones in homosexual men
    Ivanka Savic
    Department of Clinical Neuroscience, Karolinska University Hospital, 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 102:7356-61. 2005
    ..These findings show that our brain reacts differently to the two putative pheromones compared with common odors, and suggest a link between sexual orientation and hypothalamic neuronal processes...
  16. doi Quantitative PET analyses of regional [11C]PE2I binding to the dopamine transporter--application to juvenile myoclonic epilepsy
    Ikuo Odano
    Psychiatric Section, Department of Clinical Neuroscience Karolinska Institutet, Stockholm, Sweden
    Neuroimage 59:3582-93. 2012
    ..The reference tissue models should be applied with better understanding of the biochemical nature of the radioligand and the reliability of these approaches...
  17. ncbi Odorant differentiated pattern of cerebral activation: comparison of acetone and vanillin
    Ivanka Savic
    Division of Human Brain Research, Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Hum Brain Mapp 17:17-27. 2002
    ..Acetone's limited activation of the olfactory cortex may result from a cross-modal interaction, with inhibition of acetone's odor component by its trigeminal component...
  18. doi Sexual differentiation of the human brain in relation to gender identity and sexual orientation
    Ivanka Savic
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    Prog Brain Res 186:41-62. 2010
    ....
  19. doi Migraine and olfactory stimuli
    Christina Sjöstrand
    Headache Research Centre, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Curr Pain Headache Rep 14:244-51. 2010
    ..Migraine pathophysiology likely explains this particular vulnerability. We discuss these pathophysiologic mechanisms and hypotheses relating odour intolerances and migraine...
  20. ncbi Brain imaging studies of the functional organization of human olfaction
    Ivanka Savic
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Neuroscientist 8:204-11. 2002
    ..New data from brain imaging studies suggest that this is not the case and that the specific characteristics of the sense of smell can be attributed to the engagement of limbic structures at an early stage in the signal processing...
  21. ncbi Regional reductions in serotonin 1A receptor binding in juvenile myoclonic epilepsy
    Anna Meschaks
    Division of Neurology, Neurotec, Stockholm, Sweden
    Arch Neurol 62:946-50. 2005
    ..Animal data and the high incidence of myoclonic seizures in serotonin-intoxicated patients suggest that the serotonin system may be disturbed in JME...
  22. ncbi Structural changes in patients with primary generalized tonic and clonic seizures
    Carolina Ciumas
    Department of Clinical Neuroscience, Division of Neurology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
    Neurology 67:683-6. 2006
    ..The thalamus and cerebellum also showed reduced volumes, as did the caudate and putamen. Contrary to current diagnostic criteria, regional tissue abnormalities may be present in IGE...
  23. ncbi Preparation of highly specific radioactivity [18F]flumazenil and its evaluation in cynomolgus monkey by positron emission tomography
    Nikolaj N Ryzhikov
    Institute of Human Brain, Russian Academy of Science, 9, Pavlov str, 197376, Saint Petersburg, Russia
    Nucl Med Biol 32:109-16. 2005
    ..In blocking experiments, almost all radioactivity was inhibited by the addition of unlabeled flumazenil. [18F]Flumazenil is a suitable radioligand for PET assessment of the BZR...
  24. ncbi Functional neuroimaging in multiple sclerosis with radiolabelled glia markers: preliminary comparative PET studies with [11C]vinpocetine and [11C]PK11195 in patients
    Adám Vas
    Chemical Works of Gedeon Richter Ltd, Gyomroi ut 19 21, H 1103 Budapest, Hungary
    J Neurol Sci 264:9-17. 2008
    ..The comparative analysis of the two ligands indicate that [(11)C]vinpocetine shows a number of characteristics favourable in comparison with [(11)C]PK11195...