Birgitta Sander

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. doi request reprint The reliability of immunohistochemical analysis of the tumor microenvironment in follicular lymphoma: a validation study from the Lunenburg Lymphoma Biomarker Consortium
    Birgitta Sander
    Haematologica 99:715-25. 2014
  2. pmc High expression of 5-lipoxygenase in normal and malignant mantle zone B lymphocytes
    Yilmaz Mahshid
    Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
    BMC Immunol 10:2. 2009
  3. ncbi request reprint Mantle cell lymphoma: recent insights into pathogenesis, clinical variability, and new diagnostic markers
    Birgitta Sander
    Division of Pathology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Semin Diagn Pathol 28:245-55. 2011
  4. ncbi request reprint Characterization of genetic changes in MCL by interphase FISH on tissue sections
    Birgitta Sander
    Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet and Karolinska University Hospital Huddinge, Stockholm, Sweden
    Leuk Lymphoma 48:1344-52. 2007
  5. doi request reprint The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma: correlation to overall survival
    Xiao Wang
    Division of Pathology, Department of Laboratory Medicine, Karolinska Institutet and Karolinska University Hospital Huddinge, Stockholm, Sweden
    Br J Haematol 143:248-52. 2008
  6. doi request reprint Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: growth inhibition by receptor activation
    Kristin Gustafsson
    Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet and Karolinska University Hospital Huddinge, F 46, SE 14186 Stockholm, Sweden
    Int J Cancer 123:1025-33. 2008
  7. ncbi request reprint Mantle cell lymphomas with low levels of cyclin D1 long mRNA transcripts are highly proliferative and can be discriminated by elevated cyclin A2 and cyclin B1
    Birgitta Sander
    Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden
    Int J Cancer 117:418-30. 2005
  8. doi request reprint Late-onset neutropenia associated with rituximab therapy: evidence for a maturation arrest at the (pro)myelocyte stage of granulopoiesis
    Daniel Tesfa
    Department of Medicine and Hematology Center, Karolinska Institutet at Karolinska University Hospital Huddinge, Stockholm, 14186, Sweden
    Med Oncol 25:374-9. 2008
  9. ncbi request reprint CD8+ T-cell content in diagnostic lymph nodes measured by flow cytometry is a predictor of survival in follicular lymphoma
    Björn Engelbrekt Wahlin
    Division of Hematology, Department of Internal Medicine at Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 86 Stockholm, Sweden
    Clin Cancer Res 13:388-97. 2007
  10. ncbi request reprint Cannabinoid receptor-mediated apoptosis induced by R(+)-methanandamide and Win55,212-2 is associated with ceramide accumulation and p38 activation in mantle cell lymphoma
    Kristin Gustafsson
    Department of Laboratory Medicine, Division of Pathology, Karolinska University Hospital Huddinge, F 46, SE 14186 Stockholm, Sweden
    Mol Pharmacol 70:1612-20. 2006

Collaborators

Detail Information

Publications15

  1. doi request reprint The reliability of immunohistochemical analysis of the tumor microenvironment in follicular lymphoma: a validation study from the Lunenburg Lymphoma Biomarker Consortium
    Birgitta Sander
    Haematologica 99:715-25. 2014
    ..We recommend a more objective measurement, such as computer-assisted scoring, in future studies of the prognostic impact of microenvironment in follicular lymphoma patients. ..
  2. pmc High expression of 5-lipoxygenase in normal and malignant mantle zone B lymphocytes
    Yilmaz Mahshid
    Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
    BMC Immunol 10:2. 2009
    ..In order to better understand and define the role of 5-LO in B cells, we investigated the expression of 5-LO mRNA and protein in subsets of B cells from human tonsils and different types of B cell lymphoma...
  3. ncbi request reprint Mantle cell lymphoma: recent insights into pathogenesis, clinical variability, and new diagnostic markers
    Birgitta Sander
    Division of Pathology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Semin Diagn Pathol 28:245-55. 2011
    ..In situ MCL, MCL with an indolent clinical course, and cyclin D1-negative MCL are other topics of this review...
  4. ncbi request reprint Characterization of genetic changes in MCL by interphase FISH on tissue sections
    Birgitta Sander
    Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet and Karolinska University Hospital Huddinge, Stockholm, Sweden
    Leuk Lymphoma 48:1344-52. 2007
    ..One fourth of MCL had none of the investigated additional aberrations and these tumours were in general less proliferative and some of these patients had a very long survival...
  5. doi request reprint The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma: correlation to overall survival
    Xiao Wang
    Division of Pathology, Department of Laboratory Medicine, Karolinska Institutet and Karolinska University Hospital Huddinge, Stockholm, Sweden
    Br J Haematol 143:248-52. 2008
    ..These results suggest sox11 expression as a new diagnostic marker in MCL that could be related to the clinical and biological behaviour of MCL...
  6. doi request reprint Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: growth inhibition by receptor activation
    Kristin Gustafsson
    Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet and Karolinska University Hospital Huddinge, F 46, SE 14186 Stockholm, Sweden
    Int J Cancer 123:1025-33. 2008
    ..Together, our results suggest that therapies using cannabinoid receptor ligands will have efficiency in reducing tumor burden in malignant lymphoma overexpressing CB1 and CB2...
  7. ncbi request reprint Mantle cell lymphomas with low levels of cyclin D1 long mRNA transcripts are highly proliferative and can be discriminated by elevated cyclin A2 and cyclin B1
    Birgitta Sander
    Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden
    Int J Cancer 117:418-30. 2005
    ..Several of the upregulated genes, such as TOP2A, AURORA A and RRM2 may influence a response to therapy. Identification of MCL with low cyclin D1 3'UTR is important because it seems to be associated with shorter overall survival...
  8. doi request reprint Late-onset neutropenia associated with rituximab therapy: evidence for a maturation arrest at the (pro)myelocyte stage of granulopoiesis
    Daniel Tesfa
    Department of Medicine and Hematology Center, Karolinska Institutet at Karolinska University Hospital Huddinge, Stockholm, 14186, Sweden
    Med Oncol 25:374-9. 2008
    ..Nevertheless, our data suggest that rituximab-related LON and congenital neutropenia might share similar neutropenia-causing mechanisms resulting in maturation arrest...
  9. ncbi request reprint CD8+ T-cell content in diagnostic lymph nodes measured by flow cytometry is a predictor of survival in follicular lymphoma
    Björn Engelbrekt Wahlin
    Division of Hematology, Department of Internal Medicine at Huddinge, Karolinska Institutet, Karolinska University Hospital, 141 86 Stockholm, Sweden
    Clin Cancer Res 13:388-97. 2007
    ..Follicular lymphoma is a heterogeneous disease with variable prognosis and clinical course. We hypothesized that the presence of nonmalignant T cells in the microenvironment of the tumor may affect the outcome...
  10. ncbi request reprint Cannabinoid receptor-mediated apoptosis induced by R(+)-methanandamide and Win55,212-2 is associated with ceramide accumulation and p38 activation in mantle cell lymphoma
    Kristin Gustafsson
    Department of Laboratory Medicine, Division of Pathology, Karolinska University Hospital Huddinge, F 46, SE 14186 Stockholm, Sweden
    Mol Pharmacol 70:1612-20. 2006
    ..The present data suggest that targeting CB(1)/CB(2) may have therapeutic potential for the treatment of mantle cell lymphoma...
  11. doi request reprint Expression of PTEN and SHP1, investigated from tissue microarrays in pediatric acute lymphoblastic, leukemia
    Fredrika Gauffin
    Department of Clinical Science, Intervention and Technology CLINTEC, Division of Pediatrics, Karolinska Institutet, Stockholm, Sweden
    Pediatr Hematol Oncol 26:48-56. 2009
    ..Both proteins showed a significant difference in expression compared to nonmalignant controls. The roles of PTEN and SHP1 are not well investigated in pediatric leukemia and could in the future play a role as prognostic factors...
  12. pmc Potentiation of cannabinoid-induced cytotoxicity in mantle cell lymphoma through modulation of ceramide metabolism
    Kristin Gustafsson
    Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet and Karolinska University Hospital Huddinge, Stockholm, Sweden
    Mol Cancer Res 7:1086-98. 2009
    ..Furthermore, this is the first study were the cytotoxic effect of a cannabinoid is enhanced by modulation of ceramide metabolism...
  13. doi request reprint Expression of VEGF and VEGF receptors in childhood precursor B-cell acute lymphoblastic leukemia evaluated by immunohistochemistry
    Eva Diffner
    Department of Laboratory Medicine, Clinical Research Center, Lund University, Sweden
    J Pediatr Hematol Oncol 31:696-701. 2009
    ..These novel findings suggest that VEGFR-1 may have clinical importance in childhood pre-B ALL...
  14. doi request reprint A unifying microenvironment model in follicular lymphoma: outcome is predicted by programmed death-1--positive, regulatory, cytotoxic, and helper T cells and macrophages
    Björn Engelbrekt Wahlin
    Division of Hematology, Department of Internal Medicine, Karolinska Institutet, Stockholm, Sweden
    Clin Cancer Res 16:637-50. 2010
    ..Our hypothesis was that several immune cell subsets are important for disease outcome and their individual prognostic importance should be demonstrable in the same analysis and in competition with clinical factors...
  15. ncbi request reprint Cannabinoid receptor ligands mediate growth inhibition and cell death in mantle cell lymphoma
    Jenny Flygare
    Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet, Karolinska University Hospital Huddinge, F 46, SE 141 86 Stockholm, Sweden
    FEBS Lett 579:6885-9. 2005
    ..Induction of apoptosis, as measured by FACS/Annexin V-FITC, contributed to the growth suppressive effect of Win-55,212-2. Our data suggest that cannabinoid receptors may be considered as potential therapeutic targets in MCL...